Abstract: A mobile X-ray examination apparatus has an instruction receiving device that receives an entered instruction for the mobile X-ray examination apparatus to reach a designated position. A navigation device creates an environment map of an environment of the mobile X-ray examination apparatus, determines a current position of the mobile X-ray examination apparatus according to detected environment profile information, calculates a movement trajectory of the mobile X-ray examination apparatus according to the environment map, the current position and the designated position received by the instruction receiving device, and sends corresponding information to a central control device. The central control device causes the mobile X-ray examination apparatus to reach the designated position along the movement trajectory according to the corresponding information sent by the navigation device.

Abstract: The invention provides lipid A mimics in which one or both of the sugar residues of a natural lipid A disaccharide backbone has been replaced with an aromatic group. These lipid A mimics may further differ from a natural lipid A molecule with respect to other structural characteristics, such as, a different number of phosphate groups present, changes in the number, structure and location of lipid chains and/or changes in the spacing and linkage of the sugar residues (or their aromatic replacements). The lipid A mimics may be lipid A agonists and as such may be useful as immunostimulatory agents in inducing or patenting an antibody and/or cell-mediated immune response, or may be lipid A antagonists and as such may be useful in treating or preventing a lipopolysaccharide (LPS)/lipid A-mediated disease or disorder. Also provided are methods for preparing the lipid A mimics.

Abstract: The method for measuring a time stamp unit of a remote device includes: obtaining m sets of sampled data, m is a positive integer, and m>1; calculating m estimated time stamp units according to the time stamps when packets are transmitted and the time points when the previously transmitted data packets and the subsequently transmitted data packets arrive at the measuring point; selecting, from the m estimated time stamp units, an estimated time stamp unit; and calculating a time stamp unit of the remote device according to the selected estimated time stamp unit.

Abstract: Provided in the present invention are a specific antibody of BCMA and a BCMA-targeting immune effector cell, and also provided are a chimeric antigen receptor-modified T cell prepared using the antibody and the use thereof.

Abstract: Provided are a fusion protein comprising an antibody binding area and an endocytic functional area, the encoding nucleic acid of the protein, an expression vector of same, a host cell thereof, and an immune effector cell expressing the fusion protein or the endocytic functional area or further expressing a chimeric antigen receptors. Also provided are an immunoconjugate comprising a cell-killing part and an antibody conjugate in a specifically-binding immune effector cell or an antibody of the endocytic functional area, a reagent kit and uses of the immunoconjugate, and a method for specifically removing, selecting, or enriching and detecting the immune effector cell.

Abstract: Disclosed are an Object Identifier (OID) configuration, a configuration method, an OID Resolution System (ORS) client, an OID node and a database thereof. The OID configuration method may include: a parent OID node performs Domain Name System (DNS) configuration on a service provided by an OID tree to form a DNS resource record, the OID tree including the parent OID node and at least one child OID node of the parent OID node; and the parent OID node stores the DNS resource record in a DNS database of the parent OID node. Also disclosed is a computer storage medium.

Abstract: Provided in the present invention is an antibody for anti-claudin 18A2 and an immune effector cell targeting claudin 18A2. Also provided are methods for inducing cell death and treating tumours.

Abstract: A wireless power transmission system is provided. The wireless power transmission system includes a transmitting antenna and a receiving antenna. The transmitting antenna is coupled to a power source device, and the transmitting antenna is a Yagi-Uda antenna. The transmitting antenna receives a first power signal provided by the power source device and transmits a power radiation signal toward a first direction. The receiving antenna is coupled to a rectifier, the rectifier is coupled to a power receiver, and the receiving antenna is a Yagi-Uda antenna. The receiving antenna has a predetermined distance from the transmitting antenna. The receiving antenna receives the power radiation signal and converts the power radiation signal into a second power signal. The rectifier converts the second power signal into a third power signal and transmits the third power signal to the power receiver.

Abstract: A computer-implemented method comprises identifying a computer task; determining a hardware exception source associated with the computer task; determining an exception unit associated with the hardware exception source; determining a parallelization factor associated with the hardware exception source; and determining a parallel execution scenario associated with the computer task based on the exception unit and the parallelization factor. A corresponding computer program product and computer system are also disclosed.

Abstract: The present invention discloses a time domain pilot design solution suitable for a single-carrier MIMO system. The design solution comprises a time domain pilot location design and a training sequence design. In the present invention, several identical ZCZ sequences are uniformly inserted into each of the data blocks in the same data stream to serve as training sequences, wherein the training sequences inserted into different data streams are different. In addition, the present invention also discloses a simple algorithm for pilot tracking and phase correction suitable for the time domain pilot design solution for the single-carrier MIMO system. The time domain pilot design solution for a single-carrier MIMO system and the algorithm for pilot tracking and phase correction as disclosed in the present invention can improve the performance of a system.

Abstract: Disclosed herein are methods of treating a subject exhibiting a solid tumor that expresses Glypican-3 (GPC3). The methods typically utilize g GPC3 chimeric antigen receptor immunoresponsive cells to a subject in need thereof to effect killing of tumor cells.

Abstract: A connector (100) is provided. The connector (100) includes a connector body (110) with a connector axis (X), the connector body (110) being comprised of an interface (112) at a first distal end (110a) of the connector body (110), an opening (114) at a second distal end (110b) of the connector body (110), and a conduit (116) extending from the interface (112) to the opening (114) along the connector axis (X). The connector (100) also includes a latch (120) that moves relative to the connector body (110) to selectively engage a plug connector (200), the latch (120) being comprised of a pivot end (122) coupled to the connector body (110), a manually operable end (124), and a latching feature (126) disposed between the pivot end (122) and the manually operable end (124).

Abstract: The present disclosure relates to the field of biological technologies, and discloses a method for expressing and preparing a bivalent bispecific antibody. In the present disclosure, each portion of a bivalent bispecific antibody and an immune hybrid protein thereof is respectively expressed in a suitable prokaryotic or eukaryotic cell system, separated and purified by high-performance affinity chromatography, and then spliced in vitro by trans-splicing reaction mediated by an intein, to prepare the bivalent specific antibody and an immune hybrid protein thereof. The method has high production efficiency and wide scope of application, and facilitates the separation and purification of the products. The product prepared through the present method has bivalent bispecific immune affinity and cytotoxic bioactivity. Therefore, the present disclosure provides a novel method for preparing biological drugs for directionally attacking cancers or other diseases.

Abstract: A nano-composite structure comprises of an amorphous matrix with embedded nano-crystallites. The nano-crystallites are precipitated from the amorphous matrix via heat treatment of a solution mixture of metal salts or metalorganic compounds to an appropriate temperature range and with a suitable duration, or heating of a mixture of non-crystalline compounds. The nano-crystallites are self-assembled in the amorphous matrix without forming agglomerates or distinguished grain boundaries. The nano-composite structure can be used for transparent display, transparent optical ceramics, protection armor, nuclear protection, pulsed power, high voltage electronics, high energy storage system and high power microwave systems.

Abstract: Described herein is an adaptive expert system comprising a computing device having a memory that stores programmatic instructions and a processor that executes the programmatic instructions. The adaptive expert system receives sample data comprising at least one of raw data, optical data, and electropherogram data from a DNA analysis device, said data generated from a sample containing DNA. The adaptive expert system determines at least one characteristic of the sample data. The adaptive expert system utilizes the at least one characteristic to classify the sample data and apply a predefined parameter set to the said sample data to generate an output.

Abstract: The present application provides an in-vitro committed differentiation method for inducing human induced pluripotent stem cells (hiPSCs) into Leydig cells (LCs) by neural crest stem cells (NCSCs). The hiPS-derived LCs is verified by an animal model to have the capacity of regenerating senile or injured LCs, so that a new treatment for supplementing testosterone is provided for patients suffering from hypogonadism, particularly for patients suffering from late-onset hypogonadism (LOH).

Abstract: A compound of Formula (I)) or or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating hearing loss or balance disorder: wherein R1 through R3, and L are as defined herein.

Abstract: An active motor vehicle instrument cluster system with an integrated wearable device sends data of the wearable device to the motor vehicle instrument cluster.

Abstract: Multi-functional antibody polypeptide comprises: (a) a first functional domain, specifically recognizing a cryptic epitope formed by 287th to 302nd amino acid sequence of the EGFR, shown as SEQ ID NO:1, and (b) a second functional domain, specifically recognizing the surface antigen of a human T cell.