Patents by Inventor Hua Miao

Hua Miao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7312375
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a reproduction protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the reproduction protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the reproduction protein in a transformed host cell. The invention also provides isolated transcriptional regulatory elements and polynucleotides associated therewith.
    Type: Grant
    Filed: October 18, 2004
    Date of Patent: December 25, 2007
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Karlene H. Butler, Olga Danilevskaya, Guo-Hua Miao, Michele Morgante, Hajime Sakai, Carl R. Simmons, Zude Weng, Omolayo O. Famodu, Sabine Hantke
  • Publication number: 20070261135
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a disease resistance factor. The invention also relates to the construction of a chimeric gene encoding all or a substantial portion of the disease resistance factor, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the disease resistance factor in a transformed host cell.
    Type: Application
    Filed: January 18, 2007
    Publication date: November 8, 2007
    Inventors: Perry Caimi, Omolayo Famodu, Jian-Ming Lee, Guo-Hua Miao, Carl Maxwell
  • Patent number: 7262343
    Abstract: Brassicaceae plants are disclosed that contain a mutation in a delta-12 fatty acid desaturase gene and that have altered fatty acid composition in seeds. In one embodiment, a Brassicaceae plant contains a mutation in a region having the conserved motif His-Xaa-Xaa-Xaa-His, found in delta-12 and delta-15 fatty acid desaturases. A preferred motif has the sequence His-Glu-Cys-Gly-His. A preferred mutation in this motif has the amino acid sequence His-Lys-Cys-Gly-His.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: August 28, 2007
    Assignee: Cargill, Incorporated
    Inventors: Lorin R DeBonte, Guo-Hua Miao, Zhegong Fan
  • Publication number: 20070163002
    Abstract: Seeds, plants and oils are provided having high oleic acid; low linoleic acid; and low linoleic acid plus linolenic acid; and advantageous functional or nutritional properties. Plants are disclosed that contain a mutation in a delta-12 or delta-15 fatty acid desaturase gene. Preferred plants are rapeseed and sunflower plants. Plants carrying such mutant genes have altered fatty acid composition in seeds. In one embodiment, a plant contains a mutation in a region having the conserved motif His-Xaa-Xaa-Xaa-His, found in delta-12 and delta-15 fatty acid desaturases. A preferred motif has the sequence His-Glu-Cys-Gly-His. A preferred mutation in this motif has the amino acid sequence His-Lys-Cys-Gly-His. Nucleic acid fragments are disclosed that comprise a mutant delta-12 or delta-15 fatty acid desaturase gene sequence.
    Type: Application
    Filed: January 15, 2004
    Publication date: July 12, 2007
    Inventors: Lorin DeBonte, Zhegong Fan, Guo-Hua Miao
  • Patent number: 7238781
    Abstract: This invention relates to plant defensin polypeptides, nucleic acids encoding them, and methods of use thereof. The invention also relates to a chimeric protein containing all or a portion of the plant defensin.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: July 3, 2007
    Assignee: E. I. DuPont de Nemours and Company
    Inventors: Omolayo O. Famodu, Rafael Herrmann, Albert L. Lu, Billy Fred McCutchen, Guo-Hua Miao, James K. Presnail, Zude Weng
  • Patent number: 7183457
    Abstract: This invention relates to an isolated nucleic acid fragment encoding an Mlo homolog. The invention also relates to the construction of a chimeric gene encoding all or a portion of the Mlo homolog, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the Mlo homolog in a transformed host cell.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: February 27, 2007
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: J. Antoni Rafalski, Guo-Hua Miao
  • Publication number: 20070028328
    Abstract: The preparation and use of nucleic acid fragments encoding fatty acid desaturase enzymes are described. The invention permits alteration of plant lipid composition. Chimeric genes incorporating such nucleic acid fragments with suitable regulatory sequences may be used to create transgenic plants with altered levels of unsaturated fatty acids.
    Type: Application
    Filed: September 18, 2006
    Publication date: February 1, 2007
    Inventors: Richard Brogie, Lorin Debonte, William Hitz, Guo-Hua Miao, Robert Reiter
  • Publication number: 20060277626
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a farnesyltransferase subunit. The invention also relates to the construction of a chimeric gene encoding all or a portion of the farnesyltransferase subunit, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the farnesyltransferase subunit in a transformed host cell.
    Type: Application
    Filed: August 16, 2006
    Publication date: December 7, 2006
    Inventors: Rebecca Cahoon, Timothy Helentjaris, Guo-Hua Miao
  • Patent number: 7135614
    Abstract: Plants are disclosed that contain a mutation in a delta-12 or delta-15 fatty acid desaturase gene. Preferred plants are rapeseed and sunflower plants. Plants carrying such mutant genes have altered fatty acid composition in seeds. In one embodiment, a plant contains a mutation in a region having the conserved motif His-Xaa-Xaa-His, found in delta-12 and delta-15 fatty acid desaturases. A preferred motif has the sequence His-Glu-Cys-Gly-His. A preferred mutation in this motif has the amino acid sequence His-Lys-Cys-Gly-His. Nucleic acid fragments are disclosed that comprise a sequence of at least 20 nucleotides from a mutant delta-12 or delta-15 fatty acid desaturase gene.
    Type: Grant
    Filed: December 14, 1995
    Date of Patent: November 14, 2006
    Assignee: Cargill, Incorporated
    Inventors: Lorin R. DeBonte, Zhegong Fan, Guo-Hua Miao
  • Publication number: 20060242729
    Abstract: The invention provides isolated YABBY transcription factor nucleic acids and their encoded polypeptides. The present invention provides methods and compositions relating to altering YABBY transcription factor levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Application
    Filed: December 13, 2005
    Publication date: October 26, 2006
    Inventors: Edgar Cahoon, Rebecca Cahoon, Saverio Falco, Yiwen Fang, Jian-Ming Lee, Guo-Hua Miao, Michele Morgante, Joan Odell, J. Rafalski, Hajime Sakai, Quinn Zhu, Sabine Hantke, Xiping Niu, Zheng Peizhong, Zhongsen Li
  • Patent number: 7109391
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a farnesyltransferase subunit. The invention also relates to the construction of a chimeric gene encoding all or a portion of the farnesyltransferase subunit, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the farnesyltransferase subunit in a transformed host cell.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: September 19, 2006
    Assignees: E. I. du Pont de Nemours and Company, Pioneer Hi-Bred International, Inc.
    Inventors: Rebecca E. Cahoon, Timothy George Helentjaris, Guo-Hua Miao
  • Patent number: 7109392
    Abstract: The preparation and use of nucleic acid fragments encoding fatty acid desaturase enzymes are described. The invention permits alteration of plant lipid composition. Chimeric genes incorporating mutant delta-12 fatty acid desaturase nucleic acid fragments with suitable regulatory sequences may be used to create transgenic plants with altered levels of unsaturated fatty acids.
    Type: Grant
    Filed: August 22, 2000
    Date of Patent: September 19, 2006
    Assignee: Cargill, Incorporated
    Inventors: Richard Martin Broglie, Lorin Roger DeBonte, William Dean Hitz, Guo-Hua Miao, Robert Stefan Reiter
  • Publication number: 20060037097
    Abstract: This invention relates to an isolated nucleic acid fragment encoding an Mlo homolog. The invention also relates to the construction of a chimeric gene encoding all or a portion of the Mlo homolog, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the Mlo homolog in a transformed host cell.
    Type: Application
    Filed: December 15, 2004
    Publication date: February 16, 2006
    Inventors: Rebecca Cahoon, Yiwen Fang, Graziana Taramino, Hajime Sakai, J. Rafalski, Guo-Hua Miao
  • Publication number: 20060031959
    Abstract: The invention provides isolated peptide-methionine sulfoxide reductase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering peptide-methionine sulfoxide reductase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Application
    Filed: January 7, 2005
    Publication date: February 9, 2006
    Inventors: Saverio Falco, Omolayo Famodu, Blake Meyers, Guo-Hua Miao, Joan Odell, J. Rafalski, Catherine Thorpe, Hajime Sakai, Zude Weng
  • Patent number: 6967243
    Abstract: Seeds, plants and oils are provided having high oleic acid; low linoleic acid; and low linoleic acid plus linolenic acid; and advantageous functional or nutritional properties. Plants are disclosed that contain a mutation in a delta-12 or delta-15 fatty acid desaturase gene. Preferred plants are rapeseed and sunflower plants. Plants carrying such mutant genes have altered fatty acid composition in seeds. In one embodiment, a plant contains a mutation in a region having the conserved motif His-Xaa-Xaa-Xaa-His, found in delta-12 and delta-15 fatty acid desaturases. A preferred motif has the sequence His-Glu-Cys-Gly-His. A preferred mutation in this motif has the amino acid sequence His-Lys-Cys-Gly-His. Nucleic acid fragments are disclosed that comprise a mutant delta-12 or delta-15 fatty acid desaturase gene sequence.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: November 22, 2005
    Assignee: Cargill, Incorporated
    Inventors: Lorin R. Debonte, Zhegong Fan, Guo-Hua Miao
  • Publication number: 20050229268
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a carbon catabolite repression polypeptide. The invention also relates to the construction of a chimeric gene encoding all or a portion of the carbon catabolite repression polypeptide, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the carbon catabolite repression polypeptide in a transformed host cell.
    Type: Application
    Filed: November 29, 2004
    Publication date: October 13, 2005
    Inventors: Stephen Allen, Guo-Hua Miao, Elmer Heppard, Daniel Macool, Timothy Helentjaris, Jonathan Lightner, J. Rafalski, Zude Weng, Hajime Sakai
  • Publication number: 20050216974
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a reproduction protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the reproduction protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the reproduction protein in a transformed host cell. The invention also provides isolated transcriptional regulatory elements and polynucleotides associated therewith.
    Type: Application
    Filed: October 18, 2004
    Publication date: September 29, 2005
    Inventors: Karlene Butler, Olga Danilevskaya, Guo-Hua Miao, Michele Morgante, Hajime Sakai, Carl Simmons, Zude Weng, Omolayo Famodu, Sabine Hantke
  • Publication number: 20050216973
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a vitamin E biosynthtetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the vitamin E biosynthtetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the vitamin E biosynthtetic enzyme in a transformed host cell.
    Type: Application
    Filed: May 31, 2005
    Publication date: September 29, 2005
    Inventors: Rebecca Cahoon, Sean Coughlan, Guo-Hua Miao, J. Rafalski
  • Publication number: 20050216968
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a reproduction protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the reproduction protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the reproduction protein in a transformed host cell. The invention also provides isolated transcriptional regulatory elements and polynucleotides associated therewith.
    Type: Application
    Filed: October 14, 2004
    Publication date: September 29, 2005
    Inventors: Karlene Butler, Olga Danilevskaya, Guo-Hua Miao, Michele Morgante, Hajime Sakai, Carl Simmons, Zude Weng, Omolayo Famodu, Sabine Hantke
  • Publication number: 20050193445
    Abstract: This invention relates to an isolated nucleic acid fragment encoding a vitamin E biosynthtetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the vitamin E biosynthtetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the vitamin E biosynthtetic enzyme in a transformed host cell.
    Type: Application
    Filed: February 4, 2005
    Publication date: September 1, 2005
    Inventors: Rebecca Cahoon, Sean Coughlan, Guo-Hua Miao, J. Rafalski