Patents by Inventor Hubert Sturm

Hubert Sturm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of ceftaroline fosamil
    Patent number: 9534004
    Abstract: The present invention relates to novel crystalline forms of ceftaroline fosamil and to methods for their preparation. Furthermore the present invention relates to the use of the novel forms of ceftaroline fosamil for the preparation of an antibiotic medicament. In addition the present invention relates to pharmaceutical compositions comprising an effective amount of the novel forms of ceftaroline fosamil and to methods of preparing the same. Finally the present invention relates to pharmaceutical combinations comprising an effective amount of the novel forms of ceftaroline fosamil and ?-lactamase inhibitors.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: January 3, 2017
    Assignee: SANDOZ AG
    Inventors: Josef Wieser, Hubert Sturm, Arthur Pichler, Andreas Hotter, Nolwenn Martin, Christoph Langes, Ulrich Griesser
  • Process for preparing ceftaroline fosamil
    Patent number: 9481698
    Abstract: The present invention relates to a novel process for preparing ceftaroline fosamil as well as to intermediates of this process.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: November 1, 2016
    Assignee: Sandoz AG
    Inventors: Hubert Sturm, Josef Wieser
  • PREPARATION OF MICAFUNGIN INTERMEDIATES
    Publication number: 20160264628
    Abstract: The present invention relates to the preparation of compounds, in particular to the preparation of compounds of formula (I), which may be used with a compound of formula (VI), or a salt thereof as intermediates for the preparation of antifungal agents, preferably micafungin (MICA) or a salt thereof.
    Type: Application
    Filed: May 23, 2016
    Publication date: September 15, 2016
    Inventors: Roland Barth, Kerstin Knepper, Hubert Sturm
  • NOVEL CRYSTALLINE FORMS OF CEFTAROLINE FOSAMIL
    Publication number: 20160200750
    Abstract: The present invention relates to novel crystalline forms of ceftaroline fosamil and to methods for their preparation. Furthermore the present invention relates to the use of the novel forms of ceftaroline fosamil for the preparation of an antibiotic medicament. In addition the present invention relates to pharmaceutical compositions comprising an effective amount of the novel forms of ceftaroline fosamil and to methods of preparing the same. Finally the present invention relates to pharmaceutical combinations comprising an effective amount of the novel forms of ceftaroline fosamil and ?-lactamase inhibitors.
    Type: Application
    Filed: December 19, 2013
    Publication date: July 14, 2016
    Inventors: Josef Wieser, Hubert Sturm, Arthur Pichler, Andreas Hotter, Nolwenn Martin, Christoph Langes, Ulrich Griesser
  • Process for preparing ceftaroline fosamil
    Patent number: 9382278
    Abstract: The present invention relates to a novel process for preparing ceftaroline fosamil via intermediates of Formulae (1), (3) or (4) of this process.
    Type: Grant
    Filed: September 24, 2015
    Date of Patent: July 5, 2016
    Assignee: Sandoz AG
    Inventors: Peter Kremminger, Hubert Sturm
  • Crystalline form of rivaroxaban dihydrate
    Patent number: 9266868
    Abstract: Provided are a crystalline dihydrate of Rivaroxaban, processes for the preparation thereof, pharmaceutical compositions containing the crystalline dihydrate and processes for preparing and storing the pharmaceutical compositions. Also provided are a crystalline formic acid solvate of Rivaroxaban, processes for the preparation of crystalline Rivaroxaban formic acid solvate and the use of the Rivaroxaban formic acid solvate in the manufacture of the crystalline dihydrate of Rivaroxaban.
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: February 23, 2016
    Assignee: SANDOZ AG
    Inventors: Johannes Ludescher, Hubert Sturm, Ulrich Griesser, Robert E. Ziegert-Knepper, Arthur Pichler, Mairi Haddow
  • NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL
    Publication number: 20160046655
    Abstract: The present invention relates to a novel process for preparing ceftaroline fosamil as well as to intermediates of this process.
    Type: Application
    Filed: September 27, 2013
    Publication date: February 18, 2016
    Inventors: Hubert Sturm, Josef Wieser
  • NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL
    Publication number: 20160009745
    Abstract: The present invention relates to a novel process for preparing ceftaroline fosamil via intermediates of Formulae (1), (3) or (4) of this process.
    Type: Application
    Filed: September 24, 2015
    Publication date: January 14, 2016
    Applicant: Sandoz AG
    Inventors: Peter Kremminger, Hubert Sturm
  • Method for the preparation of substituted oxazolidinones
    Patent number: 9221771
    Abstract: The present invention relates to methods for the preparation of a compound having the formula (X). Individual reaction steps as well as intermediates are additionally claimed.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: December 29, 2015
    Assignee: Sandoz AG
    Inventors: Hubert Sturm, Kerstin Knepper
  • Process for preparing ceftaroline fosamil
    Patent number: 9169239
    Abstract: The present invention relates to a novel process for preparing ceftaroline fosamil as well as to intermediates of Formulae (1), (3) or (4) of this process.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: October 27, 2015
    Assignee: Sandoz AG
    Inventors: Peter Kremminger, Hubert Sturm
  • Method for the production of ceftobiprole medocaril
    Patent number: 9139597
    Abstract: The present invention relates to a method for the production of organic compounds, in particular sodium (6R,7R)-7-[(Z)-2-(5-amino-[1,2,4]thiadiazol-3-yl)-2-hydroxyimino-acetylamino]-8-oxo-3-[(E)-(R)-1?-(5-methyl-2-oxo-[1,3]-dioxol-4-ylmethoxycarbonyl)-2-oxo-[1,3?]bipyrrolidinyl-3-ylidenemethyl]-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate (ceftobiprole medocaril), and compounds of the general formula (1) and of the general formula (2), the compounds themselves and intermediates in the production according to the invention.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: September 22, 2015
    Assignee: SANDOZ AG
    Inventors: Peter Kremminger, Johannes Ludescher, Hubert Sturm
  • Method for the production of ceftobiprole medocaril
    Patent number: 9096610
    Abstract: The present invention relates to a method for the production of organic compounds, in particular sodium (6R,7R)-7-[(Z)-2-(5-amino-[1,2,4]thiadiazol-3-yl)-2-hydroxyimino-acetylamino]-8-oxo-3-[(E)-(R)-1?-(5-methyl-2-oxo-[1,3]-dioxol-4-ylmethoxycarbonyl)-2-oxo-[1,3?]bipyrrolidinyl-3-ylidenemethyl]-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate (ceftobiprole medocaril), and compounds of the general formula (1) and of the general formula (2), the compounds themselves and intermediates in the production according to the invention.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: August 4, 2015
    Assignee: SANDOZ AG
    Inventors: Peter Kremminger, Johannes Ludescher, Hubert Sturm
  • Process for the preparation of chiral triazolones
    Patent number: 9040539
    Abstract: A process for the preparation of a chiral compound, in particular posaconazole, wherein the process comprises mixing and reacting the compounds of formula (I) Y3—NH2; of formula (IIa) 0=C?N—Y0 and/or of formula (IIb) and of formula (III) in a solvent in any order to obtain a reaction mixture containing a chiral compound of formula (IV) and/or formula (V).
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: May 26, 2015
    Assignee: SANDOZ AG
    Inventors: Michael Oberhuber, Joerg Salchenegger, Dominic De Souza, Martin Albert, Thorsten Wilhelm, Martin Langner, Hubert Sturm, Hans-Peter Spitzenstaetter
  • NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL
    Publication number: 20150073138
    Abstract: The present invention relates to a novel process for preparing ceftaroline fosamil as well as to a intermediates of this process.
    Type: Application
    Filed: September 7, 2012
    Publication date: March 12, 2015
    Applicant: Sandoz AG
    Inventors: Peter Kremminger, Hubert Sturm
  • PREPARATION OF MICAFUNGIN INTERMEDIATES
    Publication number: 20140329989
    Abstract: The present invention relates to the preparation of compounds, in particular to the preparation of compounds of formula (I), which may be used with a compound of formula (VI), or a salt thereof as intermediates for the preparation of antifungal agents, preferably micafungin (MICA) or a salt thereof.
    Type: Application
    Filed: September 7, 2012
    Publication date: November 6, 2014
    Applicant: SANDOZ AG
    Inventors: Roland Barth, Kerstin Knepper, Hubert Sturm
  • METHOD FOR THE PREPARATION OF SUBSTITUTED OXAZOLIDINONES
    Publication number: 20140213784
    Abstract: The present invention relates to methods for the preparation of a compound having the formula (X). Individual reaction steps as well as intermediates are additionally claimed.
    Type: Application
    Filed: April 11, 2012
    Publication date: July 31, 2014
    Applicant: SANDOZ AG
    Inventors: Hubert Sturm, Kerstin Knepper
  • Process for the production of bimatoprost
    Patent number: 8772544
    Abstract: The present invention relates to a process for the purification of crude bimatoprost to obtain pure bimatoprost comprising a chromatography, preferably a chromatography using an achiral stationary phase and an eluent comprising an alcohol and an apolar solvent; and crystallization of the product obtained the chromatography to obtain pure bimatoprost.
    Type: Grant
    Filed: June 10, 2009
    Date of Patent: July 8, 2014
    Assignee: Sandoz AG
    Inventors: Dominic De Souza, Martin Albert, Hubert Sturm
  • Method for the preparation of rivoraxaban
    Patent number: 8648189
    Abstract: The present invention relates to the use of a compound having the formula (II) for the preparation of a compound having the formula (V). Methods of preparing the compound having the formula (V) using the compound having the formula (II) are also described. Individual reaction steps as well as intermediates are additionally claimed.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: February 11, 2014
    Assignee: Sandoz AG
    Inventors: Hubert Sturm, Dominic De Souza, Kerstin Knepper, Martin Albert
  • CRYSTALLINE FORM OF RIVAROXABAN DIHYDRATE
    Publication number: 20130245017
    Abstract: The present invention relates to a novel crystalline dihydrate of Rivaroxaban, processes for the preparation thereof, pharmaceutical compositions comprising said crystalline dehydrate and to processes for preparing and storing said pharmaceutical compositions. The invention also relates to a crystalline formic acid solvate of Rivaroxaban, processes for the preparation of crystalline Rivaroxaban formic acid solvate and to the use of said Rivaroxaban formic acid solvate in the manufacture of the crystalline dihydrate of Rivaroxaban.
    Type: Application
    Filed: July 5, 2011
    Publication date: September 19, 2013
    Applicant: SANDOZ AG
    Inventors: Johannes Ludescher, Hubert Sturm, Ulrich Griesser, Robert E. Ziegert-Knepper, Arthur Pichler, Mairl Haddow
  • Process for preparing ceftaroline fosamil
    Patent number: RE47787
    Abstract: The present invention relates to a novel process for preparing ceftaroline fosamil as well as to intermediates of this process.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: December 31, 2019
    Assignee: Sandoz AG
    Inventors: Hubert Sturm, Josef Wieser