Abstract: A vapor delivery device includes an induction coil system. The induction coil system can include a coiled fluid tube, a coiled wire, a capsule between the coiled fluid tube and the wire, and a cooling fluid supply configured to force a cooling fluid through the capsule across the coiled wire. The induction coil system can include a closed loop ferrite core, a wire coiled around a first portion of the ferrite core, and a fluid tube coiled around a second portion of the ferrite core. A wire coil can be contained in a cartridge system removably coupleable to a disposable vapor delivery device. The system can include a fluid flow controller and induction power regulation to maintain a specific operating pressure range for vapor within a uterus or other bodily cavity, tract, or duct.

Abstract: Methods, systems, and apparatus for brain tractography by shading fiber bundles. In one aspect, a method includes forwarding patient brain data for presentation to a user; receiving, from the user, a selection of a brain parcel in response to presentation of the patient brain data; forwarding, for display to the user, tract health data comprising i) tract data for tracts connected to the brain parcel and ii) at least one metric for the tracts, the metric reflecting the health of the tracts; and taking an action in response to forwarding the tract health data.

Abstract: Disclosed are techniques for two-way synchronization of infrastructure-as-code templates and instances, including a method comprising detecting changes to a run-time state of a system and, in response to detecting a change, triggering an update of a current run-time state model. The method may further comprise, in response to updating the run-time state model, comparing the updated model to a current model using a template in a local repository instantiated as the current model. The method may further comprise, in response to the comparison determining a structural difference between the updated model and the current model, merging the updated model and the current model into a new model; and updating a local clone of a repository of the template with the new model. The method may further comprise, in response to the comparison determining no structural difference between the updated model and the current model, pushing changes to a remote repository.

Abstract: A tissue collection system for collection a sample from the body. The system includes an outer tubular member having a proximal end region to a distal end region and defining a lumen extending from the proximal end region to the distal end region, an inner tubular member slidably disposed within the lumen of the outer tubular member, the inner tubular member defining a lumen extending from a proximal end region to a distal end region of the inner tubular member, and a tissue collection device disposed adjacent to the distal end region of the inner tubular member.

Abstract: A processor may identify an action of a first device of the IoT devices. The processor may initiate a transfer from the first device to one or more other devices of the IoT devices. The processor may pause each thread being executed by the first device and the one or more other devices. The processor may transfer a unit from the first device to the one or more other devices.

Abstract: A computer-implemented method according to one aspect includes identifying environmental information for a hyper-converged infrastructure (HCI) system; and adjusting one or more resources allocated to one or more applications within the HCI system, based on the environmental information.

Abstract: A vapor delivery device includes an induction coil system. The induction coil system can include a coiled fluid tube, a coiled wire, a capsule between the coiled fluid tube and the wire, and a cooling fluid supply configured to force a cooling fluid through the capsule across the coiled wire. The induction coil system can include a closed loop ferrite core, a wire coiled around a first portion of the ferrite core, and a fluid tube coiled around a second portion of the ferrite core. A wire coil can be contained in a cartridge system removably coupleable to a disposable vapor delivery device. The system can include a fluid flow controller and induction power regulation to maintain a specific operating pressure range for vapor within a uterus or other bodily cavity, tract, or duct.

Abstract: A vapor delivery device includes an induction coil system. The induction coil system can include a coiled fluid tube, a coiled wire, a capsule between the coiled fluid tube and the wire, and a cooling fluid supply configured to force a cooling fluid through the capsule across the coiled wire. The induction coil system can include a closed loop ferrite core, a wire coiled around a first portion of the ferrite core, and a fluid tube coiled around a second portion of the ferrite core. A wire coil can be contained in a cartridge system removably coupleable to a disposable vapor delivery device. The system can include a fluid flow controller and induction power regulation to maintain a specific operating pressure range for vapor within a uterus or other bodily cavity, tract, or duct.

Abstract: A processor may identify an action of a first device of the IoT devices. The processor may initiate a transfer from the first device to one or more other devices of the IoT devices. The processor may pause each thread being executed by the first device and the one or more other devices. The processor may transfer a unit from the first device to the one or more other devices.

Abstract: A vapor delivery device includes an induction coil system. The induction coil system can include a coiled fluid tube, a coiled wire, a capsule between the coiled fluid tube and the wire, and a cooling fluid supply configured to force a cooling fluid through the capsule across the coiled wire. The induction coil system can include a closed loop ferrite core, a wire coiled around a first portion of the ferrite core, and a fluid tube coiled around a second portion of the ferrite core. A wire coil can be contained in a cartridge system removably coupleable to a disposable vapor delivery device. The system can include a fluid flow controller and induction power regulation to maintain a specific operating pressure range for vapor within a uterus or other bodily cavity, tract, or duct.

Abstract: A method and system of providing therapy to a patient's uterus is provided, which can include any number of features. The method can include the steps of inserting a uterine device into the uterus and performing a uterine integrity test to determine that the uterus is intact and not perforated. Systems for performing these methods with monitored flow rate and independent of patient height relative to the pressure source are also disclosed.

Abstract: A method and system of providing therapy to a patient's uterus is provided, which can include any number of features. The method can include the steps of inserting a uterine device into the uterus and performing a uterine integrity test to determine that the uterus is intact and not perforated. Systems for performing these methods with monitored flow rate and independent of patient height relative to the pressure source are also disclosed.

Abstract: A method and system of providing therapy to a patient's uterus. The method can include the steps of inserting a uterine ablation device into the uterus; expanding a distal anchor; inflating a proximal balloon to pull the distal anchor proximally and seat the distal anchor against the internal os of the uterus; inflating a central balloon to seal the cervix; delivering vapor from the uterine ablation device into the uterus; and condensing the vapor on tissue within the uterus. The system can include a cervical collar adapted to place a distal portion of the device within the uterus when the cervical collar contacts an external os of the cervix.

Abstract: A method and system of providing therapy to a patient's uterus is provided, which can include any number of features. The method can include the steps of inserting a uterine device into the uterus and performing a uterine integrity test to determine that the uterus is intact and not perforated. If it is determined that the uterus is not perforated, a patency test can be performed to determine that the uterine device is not clogged or embedded in tissue. If the uterus is intact and the device is not clogged or embedded in tissue, the uterus can be treated with the uterine device, e.g., uterine ablation. Systems for performing these methods are also disclosed.

Abstract: A method and system of providing therapy to a patient's uterus. The method can include the steps of inserting a uterine ablation device into the uterus; expanding a distal anchor; inflating a proximal balloon to pull the distal anchor proximally and seat the distal anchor against the internal os of the uterus; inflating a central balloon to seal the cervix; delivering vapor from the uterine ablation device into the uterus; and condensing the vapor on tissue within the uterus. The system can include a cervical collar adapted to place a distal portion of the device within the uterus when the cervical collar contacts an external os of the cervix.

Abstract: Computer-implemented methods, systems and computer program products that leverage infrastructure code (IaC) to provision applications in a computing environment as virtual resources. A plurality of containers operating parallel to one another process resource provisioning requests. A central application provisioner orchestrates the containerized provisioning of resources using IaC. Application provisioner introspects IaC templates defining the provisioning request and creates a graph of the templates, mapping requested resources to containers based on the specification of the containers available. Application provisioner spins up idle containers and distributes resource provisioning tasks amongst the idle containers. An idle container provisions an assigned resource and outputs individual state information describing the provisioned resource.

Abstract: Computer-implemented methods, systems and computer program products that leverage infrastructure code (IaC) to provision applications in a computing environment as virtual resources. A plurality of containers operating parallel to one another process resource provisioning requests. A central application provisioner orchestrates the containerized provisioning of resources using IaC. Application provisioner introspects IaC templates defining the provisioning request and creates a graph of the templates, mapping requested resources to containers based on the specification of the containers available. Application provisioner spins up idle containers and distributes resource provisioning tasks amongst the idle containers. An idle container provisions an assigned resource and outputs individual state information describing the provisioned resource.

Abstract: Disclosed are methods for polynucleotide sequencing that detect the location of selected nucleobases with greater precision. The methods can be used to determine the location and nature of modified bases in a polynucleotide, that is, non-canonical bases, or to improve accuracy of sequencing of “problem” regions of DNA sequencing such as homopolymers, GC rich areas, etc. The sequencing method exemplified is nanopore sequencing. Nanopore sequencing is used to generate a unique signal at a point in a polynucleotide sequence where an abasic site (AP site, or apurinic or apyrimidinic site) exists. As part of the method, an abasic site is specifically created enzymatically using a DNA glycosylase that recognizes a pre-determined nucleobase species and cleaves the N-glycosidic bond to release only that base, leaving an AP site in its place.

Abstract: Disclosed are methods for polynucleotide sequencing that detect the location of selected nucleobases with greater precision. The methods can be used to determine the location and nature of modified bases in a polynucleotide, that is, non-canonical bases, or to improve accuracy of sequencing of “problem” regions of DNA sequencing such as homopolymers, GC rich areas, etc. The sequencing method exemplified is nanopore sequencing. Nanopore sequencing is used to generate a unique signal at a point in a polynucleotide sequence where an abasic site (AP site, or apurinic or apyrimidinic site) exists. As part of the method, an abasic site is specifically created enzymatically using a DNA glycosylase that recognizes a pre-determined nucleobase species and cleaves the N-glycosidic bond to release only that base, leaving an AP site in its place.

Abstract: Embodiments provide optimized deployment of workloads. A first workload to be deployed in at least one data center of a plurality of data centers is received. A first plurality of candidate data centers is selected from the plurality of data centers, and the first workload is deployed to each of the first plurality of candidate data centers. A first performance metric is collected from each respective data center of the first plurality of candidate data centers based on execution of the first workload deployed at the respective data centers, and a first optimal data center from the first plurality of candidate data centers is identified based on the first performance metrics. The first workload is removed from each of the first plurality of candidate data centers, other than the identified first optimal data center.