Abstract: It has been found that an inhibitor of the renin-angiotensin system is useful for the treatment or prevention of a condition associated with hypoxia or impaired metabolic function or efficiency. In particular, it may be used in connection with therapy of stroke or its recurrence, the acute treatment of myocardial infarction, and the treatment or prevention of wasting or cachexia, and is thus useful in treatment of the symptoms and signs of ageing. It may also be used to enhance function in healthy subjects.

Abstract: Inbound packets received by a physical network adapter of a processing device are routed by evaluating an inbound frame to determine if an inbound frame destination MAC address is associated with the processing device and determining whether the inbound frame should be routed to a corresponding logical interface or to drop the inbound frame if the inbound frame destination MAC address is equal to a virtual MAC address supported by the processing device. If it is determined that the inbound frame should be routed to the corresponding logical interface, then any necessary layer 3 functions are performed and the inbound frame is routed to the corresponding logical interface, thereby combining both layer 2 and layer 3 routing into a single logical function.

Abstract: Testing and evaluating a directory service of a distributed computing environment. Information related to the directory service is collected and a ruleset is executed to identify one or more problem issues as a function of the collected information. The identified problem issue includes a corresponding solution that may be applied to the directory service. A report representative of the identified problem issue and corresponding solution is generated and provided to a directory service administrator or a service engineer.

Abstract: An apparatus (10) for use in boring is described, the apparatus including a rotatable drive shaft (12), a cam member (20) and followers (16) for converting rotational motion into reciprocal motion, and a shroud (24) having a cutting edge (26) driven by the cam member and followers. The shroud may be selectively engageable with the cam member and followers, allowing the drive shaft to be removed through the shroud. A fluid circulation arrangement (31), (13) allows air to be injected into loose drilling substrate, so assisting removal of drill cuttings from the boring apparatus. Also described is a drill string incorporating a similar arrangement, allowing the drill string to be reciprocated within a bore. The drill string may further include casing sections, which may have intumescent coatings to allow the sections to be fixed in a wellbore.

Abstract: A plurality of embodiments of improved ergonomic keyboards for interfacing with a user's arms, wrists, hands and fingers in a more natural way, i.e., in ways that are optimally suited to human typing. In various non-limiting embodiments, the invention provides optimal finger pressing angles, provides optimal range(s) for “gable” angling, flattens the outer edges of the gable, thins key patterns of split key arrangements, raises (or lowers) the wrist rest to an optimal position, and/or splits the wrist rest into two (or more) components.

Abstract: An invention is disclosed for coupling a computer/display monitor combination with a dedicated sight recognition sensor that is capable of detecting head and/or eye movement from a user. When a sight recognition sensor for a given computer/display monitor combination detects that user sight is being fixed on the monitor, it relays this information to a switch connecting the sensor with its paired monitor and computer. The switch also automatically links a shared keyboard/mouse combination with the computer that is paired to the selected display monitor in view of the user, in order to allow input(s) to be sent from the keyboard and/or mouse to that computer. This link remains active until another sight recognition sensor detects vision being fixed upon a different monitor.

Abstract: A wellbore system for simultaneously drilling a wellbore into an earth formation and producing hydrocarbon fluid from the wellbore, is provided. The system comprises a production tubing extending into the wellbore and having a hydrocarbon fluid inlet arranged in a first part of the wellbore in fluid communication with a hydrocarbon fluid bearing zone of the earth formation, and a drilling riser extending through the production tubing and having a drilling fluid inlet in fluid communication with a second part of the wellbore, said second wellbore part being scaled from said first wellbore part. A drill string extends through the drilling riser and into said second wellbore part so as to allow further drilling of the wellbore.

Abstract: Systems and methods for associating a device to a peripheral that is communicating to a game console or computing device. The peripheral is initially bound to a port of the game console or computing device. The device binds to the game console or computing device via an automatic or user-initiated sequence and then correlated to the port assigned to the peripheral. Data that is associated with the peripheral is communicated to the device after being correlated. The device and peripheral may also be associated based on a user profile. When the user signs-in to the game console or computing device, the device is associated to the peripheral via a peripheral identifier and configuration information in the profile.

Abstract: It has been found that inhibitors of the renin-angiotensin system are useful for the treatment or prevention of conditions associated with hypoxia or impaired metabolic function or efficiency. In particular, they may be used in connection with therapy of stroke or its recurrence, the acute treatment of myocardial infarction, and the treatment or prevention of wasting or cachexia, and are thus useful in treatment of the symptoms and signs of aging. These inhibitors may also be used to enhance function in healthy subjects.

Abstract: An inhibitor of the renin-angiotensin system is useful for the treatment or prevention of the lipodystrophy syndrome, e.g. in AIDS patients also receiving anti-retroviral therapy.

Abstract: It has been found that inhibitors of the rennin-angiotensin system are useful for the treatment or prevention of conditions associated with hypoxia or impaired metabolic function or efficiency. In particular, they may be used in connection with therapy of stroke or its recurrence, the acute treatment of myocardial infarction, and the treatment or prevention of wasting or cachexia, and are thus useful in treatment of the symptoms and signs of aging. These inhibitors may also be used to enhance function in healthy subjects.

Abstract: An inhibitor of the rennin-angiotensin system is useful for the treatment or prevention of the lipodystrophy syndrome, e.g. in AIDS patients also receiving anti-retroviral therapy.

Abstract: An apparatus (10) for use in boring is described, the apparatus including a rotatable drive shaft (12), a cam member (20) and followers (16) for converting rotational motion into reciprocal motion, and a shroud (24) having a cutting edge (26) driven by the cam member and followers. The shroud may be selectively engageable with the cam member and followers, allowing the drive shaft to be removed through the shroud. A fluid circulation arrangement (31), (13) allows air to be injected into loose drilling substrate, so assisting removal of drill cuttings from the boring apparatus. Also described is a drill string incorporating a similar arrangement, allowing the drill string to be reciprocated within a bore. The drill string may further include casing sections, which may have intumescent coatings to allow the sections to be fixed in a wellbore.

Abstract: A field electron emission material is formed by coating a substrate (221, 230) having an electrically conductive surface with a plurality of electrically conductive particles (223, 231). Each particle has a layer of electrically insulating material (222, 232) disposed either in a first location between the conductive surface of the substrate (221) and the particle (223), or in a second location between the particle (231) and the environment (237) in which the field electron emission material is disposed, but not in both of such first and second locations, so that at least some of the particles (223, 231) form electron emission sites at such first or second locations. A number of field emission devices are disclosed, utilizing such electron emission material.

Abstract: A number of cam-operated devices such as power tools 10 are described, the tools having rotary drive means 24 for rotating a drive shaft 36 having a cylinder cam 42 mounted thereon. A pair of cam followers 54 are located within a cam track 44 provided on the cam member 42, such that rotation of the cam 42 causes axial movement of the cam followers 54, which may be attached to a drive shaft 48 and a tool bit 12.

Abstract: A field electron emission material has a substrate with an electrically conductive surface. Electron emission sites on the conductive surface each include a layer of electrically insulating material to define a primary interface region between the conductive surface and the insulating layer, and a secondary interface region between the insulating layer and the vacuum environment,. Each primary interface region is treated or created so as to enhance the probability of electron injection form the conductive surface into the insulating layer. Each primary interface region after such treatment or creation is either an insulator or graded from conducting adjacent the conductive surface to insulating adjacent the insulating layer.

Abstract: A field electron emission material is formed by coating a substrate (221, 230) having an electrically conductive surface with a plurality of electrically conductive particles (223, 231). Each particle has a layer of electrically insulating material (222, 232) disposed either in a first location between the disposed either in a first location between the conductive surface of the substrate (221) and the particle (223), or in a second location between the particle (231) and the environment (237) in which the field electron emission material is disposed, but not in both of such first and second locations, so that at least some of the particles (223, 231) form electron emission sites at such first or second locations. A number of field emission devices are disclosed, utilising such electron emission material.

Abstract: A power tool (10) is provided having a plastic casing (12) and a scraper blade (14). The blade (14) is caused to reciprocate by an internal low power rotary motor (24) which drives a cylinder cam (28) having a sinusoidal cam track (34). A pair of studs (36) ride in the cam track (34), and drive the reciprocal movement of the blade (14). The tool (10) is substantially sealed against liquid ingress by means of an elastomeric membrane within the casing (12), and may be used as a marine growth remover, for defouling boats and the like.

Abstract: It has been found that inhibitors of the renin-angiotensin system are useful for the treatment or prevention of conditions associated with hypoxia or impaired metabolic function or efficiency. In particular, they may be used in connection with therapy of stroke or its recurrence, the acute treatment of myocardial infarction, and the treatment or prevention of wasting or cachexia, and are thus useful in treatment of the symptoms and signs of aging. These inhibitors may also be used to enhance function in healthy subjects.