Abstract: The present invention provides a method for establishing lung cancer cell model having vascular tubes, wherein the lung cancer cell model can be subjected to live cell real-time dynamic image analysis or fixed cell static image analysis. The method comprises: seeding a cell suspension between an upper 3D culture substrate and a lower 3D culture substrate for cultivation into a lung cancer cell model, wherein the upper 3D culture substrate and the lower 3D culture substrate are both growth factor-reduced culture media and volume of the upper 3D culture substrate is larger than volume of the lower 3D culture substrate. The lung cancer model prepared by the aforesaid method can be further applied to patency validation of a 3D-VM by using fluorophore-tagged microsphere, and to establishment of an anti-VM drug screening platform and a screening method therefor.

Abstract: The present application discloses a lithium nickel manganate positive electrode material, a preparation method therefor and an application thereof. The lithium nickel manganate positive electrode material has a molecular formula of Li?Ni?Mn2-?M?O4-?/N, where 0.95???1.1, 0.4???0.6, 0.0005???0.02, 0???0.2, M is a single-crystal dispersing element, and M is at least one of V, Nb, Ta, Mo or W; N represents a coating layer, and the coating layer includes a P compound and/or an Al compound, and a coating amount of N is 500-10000 ppm. By means of adding a small amount of a single-crystal dispersing element (V, Nb, Ta, Mo or W), a high-voltage nickel manganese material having good dispersity of single crystals is prepared. By means of uniformly coating the P compound and/or the Al compound to the lithium nickel manganate positive electrode material, the direct contact between the positive electrode material and an electrolyte, is avoided.

Abstract: Provided are a cannabichromenic acid derivative, a method for preparing same, and a composition for cognitive function improvement comprising same, in which the cannabichromenic acid derivative exhibits acetylcholinesterase inhibitory activity and butyrylcholinesterase inhibitory activity, as well as inhibitory activity against monoamine oxidase B, therefore simultaneously treating a decrease in acetylcholine levels in brain tissue and a decrease in blood butyrylcholine levels, shown in patients with dementia, and providing a more effective cognitive function improvement treatment by preventing brain cell damage.

Abstract: The invention provides novel linkers, linker conjugates, and drug conjugates thereof, as well as methods of preparation and use thereof for treating various diseases and conditions.

Abstract: In various examples, a technique for slot filling includes receiving a natural language sentence from a user and identifying a first mention span included in the natural language sentence. The technique also includes determining, using a first machine learning model, that the first mention span is associated with a first slot class included in a set of slot classes based on a set of slot class descriptions corresponding to the set of slot classes.

Abstract: An electromagnetic interference shielding film includes an insulation layer, a first adhesive layer, a porous metal layer and a conductive adhesive layer including a plurality of conductive particles. The first adhesive layer is located between the insulation layer and the porous metal layer, and the porous metal layer is formed on the first adhesive layer, and making the first adhesive layer locate between the porous metal layer and the insulation layer. The conductive adhesive layer is located on the porous metal layer so that the porous metal layer is located between the first adhesive layer and the conductive adhesive layer. The present invention further provides a preparation method thereof.

Abstract: A semiconductor device includes a substrate, a stiffener ring over the substrate, and an adhesive ring between the substrate and the stiffener ring. The adhesive ring includes a first part, a second part and a third part disposed between the first part and the second part. The first part and the second part have a first thickness, and the third part has a second thickness greater than the first thickness. The third part of the adhesive ring is covered by the stiffener ring.

Abstract: A dual-use automatic document feeder includes a tilted feeding path, a horizontal feeding path, a U-turn feeding path, an upper scanning unit and a movable document guider. The horizontal feeding path includes a front opening and a rear opening. The U-turn feeding path is connected between the tilted feeding path and the horizontal feeding path. The upper scanning unit is positioned between the front opening and the rear opening. The movable document guider is positioned at a junction between the U-turn feeding path and the horizontal feeding path. The movable document guider has a pivot end pivotally connected to the U-turn feeding path, a guiding arm slantwise extended downward and rearward from the pivot end to the horizontal feeding path, a blocking end positioned at a terminal end of the guiding arm, and an actuating end positioned at a terminal end of the blocking end.

Abstract: A semiconductor device according to the present disclosure includes a semiconductor layer, a plurality of metal isolation features disposed in the semiconductor layer, wherein certain of the metal isolation features extend through the substrate to provide for full isolation between adjacent photodetectors and certain of the metal isolation features extend partially through the semiconductor layer to provide partially isolation between adjacent photodetectors.

Abstract: Systems and methods for bending a material to a target resultant bending parameter using a bend forming tool are disclosed. The systems and methods receive values for parameters of properties of the material and of a bending process to be performed by the bend forming tool, creating or retrieving a calibration curve relating input bending parameter and resultant bending parameter based on the values from a database of calibration curves, determining a first springback compensated input bending parameter based on the target resultant bending parameter using the calibration curve, inputting the first springback compensated input bending parameter to the bend forming tool, and in a first step of bending the material, bending the material to the first springback compensated input bending parameter by applying the bending process using the bend forming tool.

Abstract: A method of fabricating a semiconductor chip includes the following steps. A bonding material layer is formed on a first wafer substrate and is patterned to form a first bonding layer having a strength adjustment pattern. A semiconductor component layer and a first interconnect structure layer are formed on a second wafer substrate. The first interconnect structure layer is located. A second bonding layer is formed on the first interconnect structure layer. The second wafer substrate is bonded to the first wafer substrate by contacting the second bonding layer with the first bonding layer. A bonding interface of the second bonding layer and the first bonding layer is smaller than an area of the second bonding layer. A second interconnect structure layer is formed on the semiconductor component layer. A conductor terminal is formed on the second interconnect structure layer.

Abstract: An injection molding method is provided. A molding device is provided and includes a first mold, a second mold over the first mold and a mold cavity defined by the first mold and the second mold. A first mixture is injected into the mold cavity through a first feeding port. A first component is formed from the first mixture. A second mixture is injected into the mold cavity through a second feeding port. A second component is formed from the second mixture. The second component is at least partially contact with the first component, and the first component and the second component have different physical properties.

Abstract: The invention provides novel auristatin analogs and immunoconjugates thereof, as well as pharmaceutical compositions and methods of preparation and use for treating various diseases and disorders (e.g., cancer).

Abstract: The present invention provides a gas processing module, a gas processing method and a gas-phase organic compound processing method. A gas processing module comprises a cavity, a gas input unit, a light source, a photocatalyst, a liquid input unit, a gas discharge unit and a liquid discharge unit. The gas input unit is communicated with the inside of the cavity and used for supplying a to-be-processed gas comprising a gas-phase organic compound into the cavity. The light source is arranged in the cavity and used for providing a first light. The photocatalyst is arranged in the cavity, and at least a portion of the gas-phase organic compound of the to-be-processed gas which comes into contact with the photocatalyst generates an organic compound product under the action of the photocatalyst when irradiated by the first light.

Abstract: A zoom optical system includes a first lens group, a position of which with respect to an imaging plane is adjustable, and including first and second lenses. The zoom optical system also includes a second lens group of which a position with respect to the imaging plane is adjustable and includes third to fifth lenses. The zoom optical system further includes a third lens group including a sixth lens. An object-side surface of the first lens is convex.

Abstract: A coil module is provided, including a second coil mechanism. The second coil mechanism includes a third coil assembly and a second base corresponding to the third coil assembly. The second base has a positioning assembly corresponding to a first coil mechanism.

Abstract: An improved modularized socket structure comprises: a main socket module, first, second and third polar main jacks are formed on a main conductive component of the module; at least one expansion socket module, first, second and third polar expansion jacks are formed on an expansion conductive component of the module; a sub-socket module, first, second and third polar sub-jacks are formed on a sub-conductive component of the module; and an expansion conductive plate set comprising first, second and third conductive plates, the first conductive plate has first extension portions inserted into first polar main jack, first polar expansion jack and first polar sub-jack, the second conductive plate has second extension portions inserted into second polar main jack, second polar expansion jack and second polar sub-jack, and the third conductive plate has third extension portions inserted into third polar main jack, third polar expansion jack and third polar sub-jack.

Abstract: A method of manufacturing a semiconductor device includes forming a photoresist layer over a substrate. A first precursor and a second precursor are combined. The first precursor is an organometallic having a formula: MaRbXc, where M is one or more of Sn, Bi, Sb, In, and Te, R is one or more of a C7-C11 aralkyl group, a C3-C10 cycloalkyl group, a C2-C10 alkoxy group, and a C2-C10 alkylamino group, X is one or more of a halogen, a sulfonate group, and an alkylamino group, and 1?a?2, b?1, c?1, and b+c?4, and the second precursor is one or more of water, an amine, a borane, and a phosphine. The photoresist layer is selectively exposed to actinic radiation to form a latent pattern. The latent pattern is developed by applying a developer to the selectively exposed photoresist layer.

Abstract: A self-shielded and computer controlled system for performing non-invasive stereotactic radiosurgery and precision radiotherapy using a linear accelerator mounted within a two degree-of-freedom radiation shield coupled to a three-degree of freedom patient table is provided. The radiation shield can include an axial shield rotatable about an axial axis and an oblique shield independently rotatable about an oblique axis, thereby providing improved range of trajectories of the therapeutic and diagnostic radiation beams. Such shields can be balanced about their respective axes of rotation and about a common support structure to facilitate ease of movement. Such systems can further include an imaging system to accurately deliver radiation to the treatment target and automatically make corrections needed to maintain the anatomical target at the system isocenter.

Abstract: A system for manufacturing a lithium ion secondary battery includes an unwinder supplying a current collector to be coated to a predetermined position, a coating device coating a coating liquid on the current collector, a drying device drying the coated current collector, and a rewinder winding the coated current collector passing through the drying device at a predetermined position.