Abstract: The present invention relates to salt forms of the phosphoinositide 3-kinase (PI3K) inhibitor (S)-7-(1-(9H-purin-6-ylamino)ethyl)-6-(3-fluorophenyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, pharmaceutical compositions comprising the same, and methods of using the salts and compositions for the treatment of PI3K-associated diseases such as cancer.

Abstract: The present disclosure relates to a system and method for locating a target subject associated with an X-ray system. The X-ray system may include an X-ray source, a detection component, an arm, and a platform. The X-ray system may also include a first positioning component, a second positioning component, or a third positioning component. The first positioning component may be configured to determine a target point where a region of interest (ROI) of the target subject locates. The second positioning component may be configured to locate the target subject. The third positioning component may be configured to obtain location information of a target device associated with the target subject in real-time.

Abstract: The present disclosure relates to a system and method for locating a target subject associated with an X-ray system. The X-ray system may include an X-ray source, a detection component, an arm, and a platform. The X-ray system may also include a first positioning component, a second positioning component, or a third positioning component. The first positioning component may be configured to determine a target point where a region of interest (ROI) of the target subject locates. The second positioning component may be configured to locate the target subject. The third positioning component may be configured to obtain location information of a target device associated with the target subject in real-time.

Abstract: The present disclosure relates to a system and method for locating a target subject associated with an X-ray system. The X-ray system may include an X-ray source, a detection component, an arm, and a platform. The X-ray system may also include a first positioning component, a second positioning component, or a third positioning component. The first positioning component may be configured to determine a target point where a region of interest (ROI) of the target subject locates. The second positioning component may be configured to locate the target subject. The third positioning component may be configured to obtain location information of a target device associated with the target subject in real-time.

Abstract: The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.

Abstract: The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase 1 (JAK1) and are useful in the treatment of diseases related to the activity of JAK1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.

Abstract: The present invention is related to crystalline forms of (S)-7-(1-(9H-purin-6-ylamino)ethyl)-6-(3-fluorophenyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one which is a PI3K inhibitor useful in the treatment of cancer and other diseases.

Abstract: The present invention is related to crystalline forms of (S)-7-(1-(9H-purin-6-ylamino)ethyl)-6-(3-fluorophenyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one which is a PI3K inhibitor useful in the treatment of cancer and other diseases.

Abstract: The present invention provides salt forms of (R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile that are useful in the modulation of Janus kinase activity and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.

Abstract: A manufacturing method for a polymer stabilized vertical alignment (PS-VA) liquid crystal panel includes: forming a first substrate of PS-VA liquid crystal panel, the first substrate including a common electrode; forming a second substrate of the PS-VA liquid crystal panel, the second substrate including a pixel electrode; forming a liquid crystal layer between the first and second substrates, the liquid crystal layer containing negative liquid crystal molecules and ultraviolet-curable resin; applying an electrical voltage that exceeds a rotation threshold of the liquid crystal layer to the common electrode and the pixel electrode; and reciprocally moving an ultraviolet light source, which is composed of at least two ultraviolet light sources that are distributed parallel to each other in a first direction and respectively extend in a second direction, in such a direction as to have accumulation of ultraviolet light received by the ultraviolet-curable resin of the liquid crystal layer homogenized.

Abstract: The present invention is related to crystalline forms of (S)-7-(1-(9H-purin-6-ylamino) ethyl)-6-(3-fluorophenyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one which is a PI3K inhibitor useful in the treatment of cancer and other diseases.

Abstract: A method comprising allocating one or more detection tones of a sync symbol for crosstalk-free feedback data estimation, wherein the one or more detection tones are a quiet signal; transmitting the one or more detection tones to a computing device, receiving the crosstalk-free feedback data from the computing device, wherein the crosstalk-free feedback data comprises data associated with a background noise detected during the detection tones; determining an optimized PSD based at least in part on the crosstalk-free feedback data; and adjusting a transmission PSD of a plurality of tones based at least in part on the optimized PSD.

Abstract: A method for making integrated circuit (IC) packages includes providing a leadframe strip having a plurality of leadframe units and providing the leadframe strip to an operating station. The operating station is operable to perform one or more tests on the plurality of leadframe units in the making of IC packages. The method includes obtaining a database that has the locations of leadframe units in the leadframe strip stored in the database. The method also includes performing the one or more tests on the plurality of leadframe units and updating the database in response to the results of the testing.

Abstract: A portable power source with removal warning function includes a large battery, a interface, a charging and discharging circuit, a wireless communication module, an alarm module; and a processor. The interface can connect to one of an external power supply and battery (ED battery) of an electronic device. The charging and discharging circuit can charge and allow discharge of the large battery and the charging of an ED battery. The wireless communication module can communicate between the portable power source and the electronic device. The processor can determine whether a distance between the portable power source and the electronic device is within or beyond a preset distance and control the alarm module to sound if the distance is beyond the preset distance.

Abstract: The present disclosure relates to a collimator. The collimator may include a motor, a transmission unit having a first end and a second end, and a leaf unit having a leaf. The first end of the transmission unit may be connected to the motor and the second end of the transmission unit may be connected to the leaf. The present disclosure also relates to a collimator system. The collimator system may include a leaf module having a leaf, a driving module having a motor configured to drive the leaf, and a processing module to generate a movement profile of the leaf. The movement profile of the leaf may include a first speed during a first stage, a second speed of the leaf during a second stage, and a third speed of the leaf during a third stage.

Abstract: The invention relates to a method of synchronizing clocks of at least two devices in a network and a corresponding wireless device for synchronizing its clock with another wireless device. The method comprises steps of: transmitting a synchronization signal to said at least one second device to determine at least one time offset between a clock of the first device and at least one clock associated with said at least one second device; receiving said at least one time offset from said at least one second device; determining a time interval for the first device based on a time offset parameter corresponding to said at least one time offset, after which time interval the first device transmits a next synchronization signal to said at least one second device. With this method, the radio station is able to reduce its power consumption when the time offset between the first device and the second device is small.

Abstract: The present invention provides piperidin-4-yl azetidine derivatives, as well as their compositions and methods of use, that modulate the activity of Janus kinase 1 (JAK1) and are useful in the treatment of diseases related to the activity of JAK1 including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.

Abstract: A method in a radio network node for ranking cells within a group of cells in a cellular network is provided. The radio network node is serving a first cell, in the group of cells. The radio network node receives (201) power level measurements from one or more user equipments. The power level measurements respectively indicate a power level in at least one cell of the group of cells where the respective one or more user equipments is active. The radio network node then ranks (202) importance of the cells in the group of cells, both based on the power level measurements, and on the number, for each cell out of the group of cells, of user equipments whose power level measurements indicate that the respective cell has the highest power level.

Abstract: A manufacturing method for a polymer stabilized vertical alignment (PS-VA) liquid crystal panel includes: forming a first substrate of PS-VA liquid crystal panel, the first substrate including a common electrode; forming a second substrate of the PS-VA liquid crystal panel, the second substrate including a pixel electrode; forming a liquid crystal layer between the first and second substrates, the liquid crystal layer containing negative liquid crystal molecules and ultraviolet-curable resin; applying an electrical voltage that exceeds a rotation threshold of the liquid crystal layer to the common electrode and the pixel electrode; and reciprocally moving an ultraviolet light source, which is composed of at least two ultraviolet light sources that are distributed parallel to each other in a first direction and respectively extend in a second direction, in such a direction as to have accumulation of ultraviolet light received by the ultraviolet-curable resin of the liquid crystal layer homogenized.

Abstract: A multi-chip structure comprises a switch system on chip (switch SOC), a plurality of serializer/deserializer (SerDes) chips positioned around the switch SOC, and a plurality of inter-chip interfaces for connecting the switch SOC to the plurality of SerDes chips, respectively.