Abstract: The present application relates to a preparation method for an antibody-drug conjugate and an application, and in particular, to a compound, or a tautomer, mesomer, racemate, enantiomer, and diastereomer, or mixture thereof, or a pharmaceutically acceptable salt, prodrug or solvate thereof, a preparation method for the compound and related antibody-drug conjugates, and a use of the same in the preparation of drugs for the treating cancer.

Abstract: An example method of packet processing in a host cluster of a virtualized computing system includes: receiving traffic at packet processing software of a hypervisor executing on a host of the host cluster; processing the traffic using a network service of the packet processing software in the hypervisor; redirecting the traffic to a service virtual machine (VM) in the host cluster through a virtual network interface card (vNIC) of the service VM; sending metadata from the network service of the packet processing software to the service VM; processing the traffic and the metadata through at least one network service executing in the service VM; returning the traffic from the service VM to the packet processing software of the hypervisor; and forwarding, by the packet processing software, the traffic to a destination.

Abstract: The present invention relates to a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following reaction scheme: wherein LG, A, n, m and p are as defined in the Summary of the Invention.

Abstract: The present application relates to a method for preparing an antibody drug conjugate and an application thereof. Specifically, the present application relates to a compound, or a tautomer, mesomer, racemate, enantiomer, and diastereomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt, prodrug or solvate thereof, as well as a method for preparing the compound and related antibody drug conjugates and use thereof in the preparation of drugs for the treatment of cancers.

Abstract: This application provides a screen casting method, a device, and a storage medium. In a screen casting process, when a sound output device is switched to the screen casting transmit end, whether the screen casting transmit end outputs a sound depends on a current status of an audio status switching control, thereby ensuring that whether the screen casting transmit end outputs a sound can be consistent with an expectation of a user in a screen casting scenario. In addition, in the screen casting method provided in this application, when whether the screen casting transmit end outputs a sound is set based on a click operation performed by the user on the audio status switching control, an icon corresponding to the audio status switching control is dynamically modified based on an audio status (mute or non-mute) corresponding to the audio status switching control.

Abstract: A ray scanning apparatus, including: a conveying device; a ray source assembly including a plurality of ray source modules arranged around the scanning area in a non-enclosed structure opened on one side of the scanning area; and a detector assembly including a plurality of detector sets arranged around the scanning area in a non-enclosed structure opened on one side of the scanning area, where the opening of the non-enclosed structure of the ray source assembly is opposite to the opening of the non-enclosed structure of the detector assembly, the plurality of detector sets are fixed in a same plane perpendicular to the conveying direction of the object under inspection, and the plurality of ray source modules of the ray source assembly are arranged in a plurality of different planes perpendicular to the conveying direction of the object under inspection.

Abstract: This disclosure relates to GLP-1 agonists of Formula (I), including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.

Abstract: A LiS battery includes a heterostructure deposited on a sponge of carbon nanotubes followed by annealing. The heterostructure may be performed by depositing layers of TiN and TiO2, such as TiN followed by TiO2. Following annealing, the TIN and TiO2 may be distributed substantially uniformly in the heterostructure. In some embodiments, the TiN layer has a thickness of 10 nm and the TiO2 layer has a thickness of 5 nm.

Abstract: Embodiments of the present application provides a ray scanning apparatus, which includes: a conveying device for conveying an object under inspection to pass through a scanning region of the ray scanning apparatus; a ray source assembly including a plurality of ray source modules, each of the ray source modules including at least one ray source point emitting a ray beam; and a detector assembly for detecting rays transmitting through the object under inspection during scanning and including a plurality of detector sets.

Abstract: Systems and methods for accessing block storage devices are provided. In particular, a computing device may receive a write request including an uncompressed data and an uncompressed block address associated with the uncompressed data, generate compressed data by compressing the uncompressed data, determine a plurality of mapping candidates of compressed data blocks in the block storage devices based on the uncompressed block address, select a compressed data block from the plurality of mapping candidates that has sufficient capacity to store the compressed data, write the compressed data to the selected compressed data block, update metadata of the selected compressed data block to link the uncompressed block address to a compressed block address of the selected compressed data block, and write the selected compressed data block back to a respective block storage device of the block storage devices.

Abstract: Embodiments of the present disclosure provide a MIMO communication method and system, and a receiver node. The method includes: receiving, by a number of optical detection modules of a receiver node, optical signals transmitted by a number of optical transmission modules of a transmitter node. Different optical detection modules of the receiver node have different orientations, and different optical transmission modules of the transmitter node have different orientations.

Abstract: The present disclosure relates to a computer-implemented method for genetic placement of analog and mix-signal circuit components. Embodiments may include receiving an unplaced layout associated with an electronic circuit design and grouping requirements. Embodiments may also include identifying one or more instances that need to be placed in the unplaced layout and areas of the unplaced layout configured to receive the instances. Embodiments may further include analyzing one or more instances that need to be placed in the unplaced layout and the areas of the unplaced layout configured to receive the instances, wherein analyzing is based upon a row-based data structure. Embodiments may also include determining a location and an orientation for each of the one or more instances based upon the genetic algorithm and generating a placed layout based upon the determined location and orientation for each of the instances.

Abstract: The present application discloses a display method and a display apparatus; and the display apparatus includes a controller configured to determine, on the basis of a schedule list and target program display information corresponding to a target EPG page, whether there is a schedule conflict; if there is a schedule conflict, determining a specified channel and specified time period corresponding to the schedule conflict; obtaining a specified schedule identifier corresponding to the specified channel in the specified time period, and displaying the specified schedule identifier on specified program information.

Abstract: A processor-implemented method including generating a depth-aware feature of an image dependent on image features extracted from image data of the image and generating image data, representing information corresponding to one or more segmentations of the image, based on the depth-aware feature and a depth-aware representation, the depth-aware representation being depth-related information and visual-related information for the image.

Abstract: A preparation method for a hollow fiber inorganic membrane to solve the problem that the existing membrane technology cannot simultaneously have high flux and a high retention rate, including the steps of: adding an inorganic material, a polymer, and a binder into an organic solvent, first performing ball milling, and then vacuumizing to obtain a casting solution; using tap water as an internal coagulant, spinning the casting solution, then using tap water and/or the organic solvent as an external coagulant, putting membrane filaments in the external coagulant, performing phase inversion under 19.5-20.5° C., taking out the membrane filaments, and then drying same to obtain a basement membrane green body; and calcining the basement membrane green body at 800-950° C. to obtain a hollow basement membrane, and preparing a separation layer on the outer surface of the hollow basement membrane to obtain the hollow fiber inorganic membrane.

Abstract: An insert for a vacuum coating machine includes a body having a flow channel. The flow channel has a staging chamber, a delivery channel, and a nozzle. The nozzle includes a two-tier step proximate a nozzle exit that is configured to application a coating out of the flow channel and onto a surface.

Abstract: A mutation site of an ideal brittle culm mutant ibc in rice, a controlling gene IBC, and use thereof are provided. The controlling gene IBC has: (1) a nucleotide sequence shown in SEQ ID NO: 1 or SEQ ID NO: 2; or (2) a nucleotide sequence of a mutant, an allele, or a derivative generated by adding, substituting, inserting or deleting one or more nucleotides. The present disclosure further provides an encoded protein of the controlling gene IBC, a recombinant construct, a recombinant host cell, a method for embrittling culms in a rice ripening stage by using the controlling gene IBC, and use thereof. In a mutant with allelic variation in the gene IBC and loss of gene editing function, culms exhibit a brittle culm phenotype at the late ripening stage, leaves are not brittle, yield traits are excellent, and other agronomic traits are not obviously changed.

Abstract: Provided is a beam-column joint of a prefabricated self-centering RC (Reinforced Concrete) frame based on an SMA (Shape Memory Alloy) material, including an RC precast column, an RC precast beam, and self-centering energy dissipation dampers arranged, and a friction energy dissipation damper. The self-centering energy dissipation damper includes an SMA kernel, an upper restraint cover plate, a lower restraint cover plate, a column-end connection reinforcing plate and a beam-end connection reinforcing plate, and a set energy dissipation gap is reserved between the SMA kernel and the upper restraint cover plate. The friction energy dissipation damper includes an in-column embedded connecting plate and a beam-end embedded connecting plate.

Abstract: The present application relates to a preparation method for and an application of an antibody conjugated drug, in particular to a compound, or a tautomer, mesomer, racemate, enantiomer, diastereomer, or mixture thereof, or a pharmaceutically acceptable salt, prodrug, or solvate thereof, preparation methods of the compound and related antibody conjugated drug, and uses thereof in the preparation of drugs for treating cancers.

Abstract: Disclosed is a decorative gas stove. The decorative gas stove includes a stove body and a viewing platform. A cavity is defined in the stove body. An energy device is provided inside the cavity for storing gaseous fuel. A supply pipe is provided inside the cavity for transporting the gaseous fuel. A water tank is provided on an upper end of the stove body and a bottom of the water tank is defined with a plurality of air outlet holes communicated with the supply pipe. An ignition portion is provided on a side wall of the water tank for igniting the gaseous fuel flowing to a water surface through the air outlet holes when the water tank is stored with water.