Abstract: The present disclosure includes cationic carrier units comprising (i) a water-soluble polymer, (ii) a positively charged carrier, (iii) a hydrophobic moiety, and (iv) a crosslinking moiety, wherein when the cationic carrier unit is mixed with an anionic payload (e.g., an antisense oligonucleotide) that electrostatically interacts with the cationic carrier unit, the resulting composition self-organizes into a micelle encapsulating the anionic payload in its core. The cationic carrier units can also comprise a tissue specific targeting moiety, which would be displayed on the surface of the micelle. The disclosure also includes micelles comprising the cationic carrier units of the disclosure, methods of manufacture of cationic carrier units and micelles, pharmaceutical compositions comprising the micelles, and also methods of treating diseases or conditions comprising administering the micelles to a subject in need thereof.

Abstract: Implementations relate to a sensor assembly for determining rotation about an axis and linear movement parallel to the axis. The sensor assembly comprises a magnetic structure comprising a north pole radially displaced from the axis and a south pole radially displaced from the axis and opposite to the north pole. The north pole and the south pole of the magnet extend radially into the direction of the axis at an axial end of the sensor assembly. The sensor assembly further comprises at least one sensor element sensitive to magnetic fields radially between the north pole and the south pole.

Abstract: An exemplary embodiment of the present disclosure provides a separator for a fuel cell, which is stacked on a reaction layer including a membrane electrode assembly (MEA). The separator includes a plate body stacked on the reaction layer, a wave pattern provided on one surface of the plate body that faces the reaction layer, the wave pattern being configured to define a reaction channel disposed between the reaction layer and the plate body and provided in a first direction in which a reactant gas is supplied, so that the reactant gas flows along the reaction channel, and a land provided along a lateral end of the wave pattern and disposed to be in contact with the reaction layer, thereby obtaining an advantageous effect of improving performance and operational efficiency.

Abstract: An embodiment of the present disclosure provides a thermal processing apparatus and an operation method thereof capable of controlling a heat distribution of a substrate at a low cost in a thermal processing process using a microwave. According to the present disclosure, a thermal processing apparatus includes a chamber that forms a thermal processing space of a substrate, a substrate support unit that is located at a lower portion of the thermal processing space and supports the substrate, and a microwave unit that is located at an upper portion of the thermal processing space and forms an electromagnetic field by the microwave in the thermal processing space.

Abstract: The present disclosure includes cationic carrier units comprising (i) a water soluble polymer, (ii) a positively charged carrier, (iii) a hydrophobic moiety, and (iv) a crosslinking moeity, wherein when the cationic carrier unit is mixed with an anionic payload (e.g., an RNA and/or DNA) that electrostatically interacts with the cationic carrier unit, the resulting composition self-organizes into a micelle encapsulating the anionic payload in its core. The cationic carrier units can also comprise a tissue specific targeting moiety, which would be displayed on the surface of the micelle. The disclosure also includes micelles comprising the cationic carrier units of the disclosure, methods of manufacture of cationic carrier units and micelles, pharmaceutical compositions comprising the micelles, and also methods of treating diseases or conditions comprising administering the micelles to a subject in need thereof.

Abstract: A recombinant vector according to an embodiment is for genome editing without inserting a replicon into the plant genome in a T0 generation plant. The recombinant vector includes a geminivirus-based replicon between the sequence of LB (left border) and sequence of RB (right border) of Ti plasmid. A method of genome editing without inserting a replicon into the plant genome in a T0 generation plant according to an embodiment includes transforming a plant cell by inserting a foreign gene to the aforementioned recombinant vector.

Abstract: A method for configuring an observable object as a digital twin in a digital twin system of any one domain is provided. The method for configuring a digital twin includes defining a purpose for expressing the observable as a digital twin in the domain, organizing data based on a role of the observable object in the domain, configuring the observable object into the digital twin based on the data for the purpose, and synchronizing the observable object and the digital twin.

Abstract: A method for determining a rotation angle of a magnet includes measuring a 3D magnetic field vector of a magnetic field generated by the magnet, wherein the 3D magnetic field vector describes at least a part of an ellipse in 3D space during a rotational movement of the magnet. The method further includes mapping the measured 3D magnetic field vector to a 2D vector based on a compensation mapping, wherein the compensation mapping is configured to map the ellipse in 3D space to a circle in 2D space. The method further includes determining the rotation angle of the magnet based on the 2D vector.

Abstract: Disclosed is a cartridge assembly. The cartridge assembly includes a body part having an upper body opened upwards and downwards, and a lower body opened upwards and downwards, and coupled to the upper body to define an interior space, in which cells are stacked upwards and downwards, together with the upper body, and a cartridge including a cover part having an upper cover that covers an upper opening formed on an upper side of the upper body, and a lower cover that covers a lower opening formed on a lower side of the lower body, a plurality of cartridges are provided, and are stacked in an upward/downward direction, and each of the cartridges includes a connection part fixedly coupled to another cartridge disposed on an upper side or a lower side thereof to be adjacent thereto.

Abstract: A separator for a fuel cell, which is stacked on a gas diffusion layer provided on a membrane electrode assembly (MEA), includes a plate body stacked on the gas diffusion layer and including a flow path part to define a reaction region to react with the membrane electrode assembly and manifold parts spaced apart from the flow path part; through-holes disposed in the plate body to guide target fluids that have passed through the manifold parts to the flow path part; and hole caps disposed on one surface of the plate body that faces the gas diffusion layer to at least partially cover the through-holes, the hole caps defining movement paths through which the target fluids move.

Abstract: In some implementations, a sensing device associated with less than a 360 degree measurement range may obtain a set of signal values. The sensing device may be configured to sense a magnetic field present at the sensing device and collect sensor data based on the magnetic field. The set of signal values may be included in the sensor data collected by the sensing device and may correspond to one or more components of the magnetic field present at the sensing device. The sensing device may determine, based on the set of signal values, a set of calibration points and a set of angular positions. The sensing device may calculate a set of calibration parameters based on the set of calibration points and the set of angular positions. The sensing device may utilize the set of calibration parameters to perform one or more safety checks.

Abstract: A magneto-resistive angle sensor system for measuring a rotational angle of a rotating component in an out-of-shaft configuration. The magneto-resistive angle sensor system including a magnet, which is attached to the rotating component. The magneto-resistive angle sensor system further including a magneto resistive sensor. A sensitive plane of the magneto-resistive sensor is positioned with an offset to the center of the magnet in an offset direction.

Abstract: A bipolar plate for a fuel cell capable of improving the cooling efficiency of a fluid passing through the bipolar plate, and a fuel cell including the same, includes a first plate, a second plate coupled to the first plate to form a channel in which a fluid flows, and a plurality of protrusions disposed apart from each other in the channel in a flow direction of the fluid.

Abstract: Provided are a simultaneous implementation method of 3D subtraction arteriography, 3D subtraction venography, and 4D color angiography through post-processing of image information of 4D magnetic resonance (MR) angiography, and a medical imaging system.

Abstract: A method of determining a position of a first object includes receiving a first component and a second component of a vector field jointly generated by the first object and by a second object. The method further includes using the second component of the vector field to provide a compensation quantity indicating a contribution of the second object to the first component of the vector field. Further, the method includes determining the position of the first object using the first component of the vector field and the compensation quantity.

Abstract: In some implementations, a sensing device associated with less than a 360 degree measurement range may obtain a set of signal values. The sensing device may be configured to sense a magnetic field present at the sensing device and collect sensor data based on the magnetic field. The set of signal values may be included in the sensor data collected by the sensing device and may correspond to one or more components of the magnetic field present at the sensing device. The sensing device may determine, based on the set of signal values, a set of calibration points and a set of angular positions. The sensing device may calculate a set of calibration parameters based on the set of calibration points and the set of angular positions. The sensing device may utilize the set of calibration parameters to perform one or more safety checks.

Abstract: A method for determining a rotation angle of a magnet includes measuring a 3D magnetic field vector of a magnetic field generated by the magnet, wherein the 3D magnetic field vector describes at least a part of an ellipse in 3D space during a rotational movement of the magnet. The method further includes mapping the measured 3D magnetic field vector to a 2D vector based on a compensation mapping, wherein the compensation mapping is configured to map the ellipse in 3D space to a circle in 2D space. The method further includes determining the rotation angle of the magnet based on the 2D vector.

Abstract: A method for increasing the efficiency of homologous recombination-based gene editing in a plant according to an embodiment of the present invention includes optimizing temperature and photoperiod conditions during tissue culture of plant cells, expressing factors required for homology-directed DNA repair (HDR) and factors for increasing the HDR efficiency by using a multiple replicon, or regulating the HDR pathway or non-homologous end joining (NHEJ) pathway.

Abstract: Disclosed are fuel cells including a membrane electrode assembly (MEA), a separator stacked on a surface of the membrane electrode assembly, a beading portion protruding from a first surface of the separator that faces the membrane electrode assembly, and a sealing member disposed between the membrane electrode assembly and the beading portion and being configured to seal a portion between the membrane electrode assembly and the separator, thereby ensuring rigidity and improving safety and reliability of the fuel cell.

Abstract: Implementations relate to a sensor assembly for determining rotation about an axis and linear movement parallel to the axis. The sensor assembly comprises a magnetic structure comprising a north pole radially displaced from the axis and a south pole radially displaced from the axis and opposite to the north pole. The north pole and the south pole of the magnet extend radially into the direction of the axis at an axial end of the sensor assembly. The sensor assembly further comprises at least one sensor element sensitive to magnetic fields radially between the north pole and the south pole.