Abstract: The present invention relates to a multivalent live influenza vaccine platform using a recombinant adenovirus. The present invention is a live attenuated vaccine platform using a recombinant virus and it is easy to inoculate because it is infected with the respiratory tract like influenza virus and exhibits a vaccine action and it is a multivalent vaccine which combines two types into one and it is a highly novel vaccine that does not need to mix viruses compared to vaccines using multiple combinations of one vaccine. The present invention is the first vaccine in which a gene obtained by fusion of two influenza antigen genes into one gene is incorporated into a recombinant virus. Instead of using the entire HA gene of influenza, but using a structurally independent HA1 gene, which is about half of the total HA gene, several types of HA genes could be fused into one.

Abstract: Disclosed are a catalyst for oxidative coupling reaction of methane, a method for preparing the same, and a method for oxidative coupling reaction of methane using the same. The catalyst includes a mixed metal oxide, which is a mixed oxide of metals including sodium (Na), tungsten (W), manganese (Mn), barium (Ba) and titanium (Ti). It is possible to obtain paraffins, such as ethane and propane, and olefins, such as ethylene and propylene, with high efficiency through the method for oxidative coupling reaction of methane using the catalyst.

Abstract: An air conditioner of present invention comprises a housing having an outer panel forming the exterior and an opening formed on the outer panel, a heat exchanger configured to exchange heat with air flowing into the housing, and a door unit configured to open or close the opening by moving forward or backward from the opening through which the heat exchanged air is discharged. Wherein the door unit comprises a door blade configured to open or close the opening, a door operating part configured to move the door blade forward or backward, and a controller configured to control the air discharged from the opening to be moved forward from the opening in a straight line or to be discharged radially from the opening by controlling a distance between the door blade and the opening.

Abstract: There are provided a printing method and a printing apparatus for increasing visibility and printed matter printed using the printing method. The printing apparatus sprays a light-absorbing composition to form a light-absorbing layer on a print medium, and then sprays a color-variable composition on the light-absorbing layer to form a color-variable layer.

Abstract: Systems and methods are disclosed for conducting spinal cord stimulation or other neurostimulation and sensing evoked compound action potential (ECAP) signals. The sensed signals may be processed to isolate ECAP features from noise and/or interfering signals. The isolated ECAP features may be used to control neurostimulation therapy for the patient and/or guide an implant procedure.

Abstract: Disclosed is a methanol and sulfuric acid co-production system capable of producing methanol and sulfuric acid in equal equivalents. Specifically, the system includes an oxidation reaction unit configured to produce methyl bisulfate (CH3OSO3H) by reacting methane gas with an acid solution in the presence of a catalyst, a reactive distillation unit disposed downstream of the oxidation reaction unit and configured to esterify methyl bisulfate (CH3OSO3H) supplied from the oxidation reaction unit with trifluoroacetic acid (CF3COOH) to obtain a product and to separate the product into methyl trifluoroacetate (CF3COOCH3) and sulfuric acid (H2SO4) through thermal distillation, and a hydrolysis reaction unit disposed downstream of the reactive distillation unit and configured to produce methanol by hydrolyzing methyl trifluoroacetate (CF3COOCH3) supplied from the reactive distillation unit, in which the reactive distillation unit recirculates the sulfuric acid resulting from separation to the oxidation reaction unit.

Abstract: Systems and methods are disclosed for conducting spinal cord stimulation or other neurostimulation and sensing evoked compound action potential (ECAP) signals. The sensed signals may be processed to isolate ECAP features from noise and/or interfering signals. The isolated ECAP features may be used to control neurostimulation therapy for the patient and/or guide an implant procedure.

Abstract: Systems and methods are disclosed for conducting spinal cord stimulation or other neurostimulation and sensing evoked compound action potential (ECAP) signals. The sensed signals may be processed to isolate ECAP features from noise and/or interfering signals. The isolated ECAP features may be used to control neurostimulation therapy for the patient and/or guide an implant procedure.

Abstract: Provided are a polyimide-based film, a window cover film, and a display panel including the same. More particularly, a polyimide-based film having excellent visibility, a window cover film using the same, and a display panel including the same are provided.

Abstract: Provided are a polyimide-based film, a window cover film, and a display panel including the same. More particularly, a polyimide-based film having different surface properties of both surfaces is provided.

Abstract: Provided herein are methods for analyzing in vivo a brain circuit. A method of the present disclosure may include using optogenetics to stimulate a first region of a brain of an individual, in conjunction with functional magnetic resonance imaging (fMRI) of different regions of the brain to determine a dynamic functional connection between individual neurons of the first region and a second region of the brain. The method may further include identifying a third region of the brain, the neurons of which region mediate the dynamic functional connection between the first and second regions.

Abstract: A server is disclosed. The server comprises: a communication interface for communicating with a user terminal device and an electronic device; a storage for storing healthcare information corresponding to an avatar of a user; and a processor for acquiring the healthcare information corresponding to the avatar of the user from the storage when information including the avatar of the user and health data is received from the user terminal device, and controlling the communication interface such that guide information for guiding user behavior is transmitted to the user terminal device and/or the electronic device on the basis of the acquired healthcare information and the received health data.

Abstract: The present disclosure provides systems and methods for estimating an orientation of an implanted deep brain stimulation (DBS) lead. Such methods include generating an initial image dataset, down-sampling a respective image or adding noise to images of the subset of the initial image dataset, and re-slicing at least a subset of the modified image dataset along an alternative primary imaging axis, to generate an integrated image dataset. The method also include partitioning the integrated image dataset into a preliminary training image dataset and a testing image dataset, and re-sizing at least a subset of the preliminary training image dataset with a localized field of view around a depicted DBS lead, to generate a training image dataset. The method further includes training a machine-learning model using the training image dataset, and executing the trained machine-learning model to estimate, during a DBS implantation procedure, an orientation of a subject implanted DBS lead.

Abstract: In some embodiments, a method of providing a neurostimulation therapy to a patient, comprises: generating electrical pulses, by an implantable pulse generator (IPG), comprising respective bursts of a plurality of anodic pulses with each anodic pulse being separated by a time gap, wherein (1) the plurality of anodic pulses comprise successively increasing charge; (2) the plurality of anodic pulses are charge limited to be sub-threshold; (3) each burst of anodic pulses is followed by a discharge phase of intermittent time periods to discharge charge build up from the anodic pulses; and (4) each successive intermittent time period increases in time through the discharge phase to avoid action potential (AP) generation; and applying the generated electrical pulses to neural tissue of the patient to inhibit neural activity of the patient.

Abstract: The present disclosure relates to a board connector comprising a plurality of RF contacts; an insulation unit; a plurality of transmit contacts and a plurality of second RF contacts, so that the first and second RF contacts are spaced apart along a first axial direction; a ground housing; a first ground contact coupled to the insulation unit, and providing shielding between the first RF contacts and the transmit contacts, with respect to the first axial direction; and a second ground contact coupled to the insulation unit, and providing shielding between the second RF contacts and the transmit contacts, with respect to the first axial direction, wherein the first ground contact provides shielding between the first RF contacts and the transmit contacts, with respect to the first axial direction, and provides shielding between the first RF contacts with respect to a second axial direction perpendicular to the first axial direction.

Abstract: In some embodiments, a method of providing a neurostimulation therapy to a patient, comprises: generating a noise pulse pattern defining a pulse train of pulses to be generated according to a noise profile in an external device; communicated the generated noise pulse pattern to an implantable pulse generator (IPG) of a patient; generating, by the IPG, a series of pulses in sequence for noise stimulation of the patient using the noise pulse pattern from the external device, wherein the IPG applies one or more randomization operations to the pulse pattern from the external device without expanding memory storage for the pulse pattern while maintaining the noise profile of the pulse pattern from the external device; and applying the series of pulses in sequence to neural tissue of the patient using one or more electrodes of one or more stimulation leads.

Abstract: An operation method of a nonvolatile memory device includes performing a 1-stage program step and a 1-stage verify step on a first word line, storing a first time stamp, performing the 1-stage program step and the 1-stage verify step on a second word line, storing a second time stamp, calculating a delay time based on the first time stamp and the second time stamp, determining whether the delay time is greater than a threshold value, adjusting at least one 2-stage verify voltage associated with the first word line from a first voltage level to a second voltage level based on the delay time, and performing a 2-stage program step and a 2-stage verify step on the first word line. A level of the at least one 1-stage verify voltage is lower than the second voltage level, and the second voltage level is lower than the first voltage level.

Abstract: This disclosure relates to a printing device for printing or dispensing a curable printing composition which is capable of changing color in response to the application of a magnetic field in the non-cured state. The printing device may be a handheld device such as a portable pen. The present disclosure further relates to curable compositions, cartridges and methods which may be used in combination with the aforementioned printing devices or in other applications.

Abstract: A display apparatus, a terminal apparatus, and controlling methods are provided. The display apparatus includes: a communicator to communicate with a terminal apparatus or a relay server in order to receive collected status information about at least one peripheral device from the terminal apparatus, a display unit to display a user interface (UI) screen; and a controller to generate a control UI for controlling the at least one peripheral device or a security UI for monitoring a peripheral space through the at least one peripheral device based on the status information about the at least one peripheral device and based on whether a communication with the terminal apparatus is possible, thereby controlling a home device t in real time according to a communication status with the terminal apparatus.

Abstract: The present disclosure pertains to a board connector comprising a plurality of RF contacts; an insulating part; a plurality of transmission contacts coupled to the insulating part between a first RF contact and a second RF contact, such that the RF contacts are spaced from each other in a first axial direction; and a ground housing to which the insulating part is coupled, the ground housing comprising a ground inner wall, a ground outer wall, and a ground connection wall coupled to each of the ground inner and outer walls, wherein the ground inner and outer walls are double-shielding walls surrounding the side of an inner space, the RF contacts are located in the inner space surrounded by the double-shielding walls, and each of the ground inner and outer walls contacts the ground housing of a counter connector inserted into the inner space.