Patents by Inventor Ian David

Ian David has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxadiazole derivatives active on sphingosine-1-phosphate (S1P)
    Patent number: 8222245
    Abstract: The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: July 17, 2012
    Assignee: Glaxo Group Limited
    Inventors: Emmanuel Hubert Demont, Jag Paul Heer, John Skidmore, Ian David Wall, Jason Witherington, Thomas Daniel Heightman, David Nigel Hurst, Christopher Norbert Johnson
  • MASS SPECTROMETER SYSTEM
    Publication number: 20120168621
    Abstract: The invention provides a mass spectrometer system (10) comprising a mass spectrometer (12) comprising a plurality of mass spectrometer stages (16, 18, 20, 44) in fluid communication from a low vacuum stage (16) to a higher vacuum stage (44). A split flow multi-stage pump (14) evacuates the mass spectrometer stages. The pump comprises a pump envelope (28) in which a plurality of pumping stages (20, 32, 34) are supported for rotation about an axis X generally parallel to the direction of flow in the mass spectrometer stages for pumping fluid from a main pump inlet (36) to a main pump outlet (38). At least part of a higher vacuum stage (44) is located within the pump envelope at the main pump inlet.
    Type: Application
    Filed: September 13, 2010
    Publication date: July 5, 2012
    Applicant: EDWARDS LIMITED
    Inventor: Ian David Stones
  • 5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRAZINE DERIVATIVES AS P2X7 MODULATORS
    Publication number: 20120172366
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein A is hydrogen, C1-4alkyl, C3-6cycloalkyl, C1-3alkoxy, C1-3alkoxy C1-4alkyl, C1-2fluoroalkyl, halogen, NR6R7, optionally substituted heteroaryl, or optionally substituted phenyl, and R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The compounds or salts are thought to modulate P2X7 receptor function and to be capable of antagonizing the effects of ATP at the P2X7 receptor. The invention also provides the use of the compound or salt in the treatment or prophylaxis of, for example, inflammatory pain, neuropathic pain, visceral pain, rheumatoid arthritis or osteoarthritis or neurodegenerative disorders.
    Type: Application
    Filed: April 28, 2010
    Publication date: July 5, 2012
    Inventors: David Kenneth Dean, Jorge Munoz-Muriedas, Mairi Sime, Jon Graham Anthony Steadman, Rachel Elizabeth Anne Thewlis, Giancarlo Trani, Ian David Wall, Daryl Simon Walter
  • Systems and methods of reducing heat loss from a gas turbine during shutdown
    Patent number: 8210801
    Abstract: A method operates a gas turbine that includes a compressor section, a turbine section and an extraction cooling system. The method includes monitoring an operation of the gas turbine, directing a cooling air flow through the extraction cooling system from the compressor section to the turbine section in response to normal operation of the gas turbine, and directing a warming air flow through the extraction cooling system to the compressor section and the turbine section in response to shutdown of the gas turbine.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: July 3, 2012
    Assignee: General Electric Company
    Inventors: Henry G. Ballard, Jr., Ian David Wilson, Stephen Christopher Chieco, Andrew Ray Kneeland, Bradley James Miller, Kenneth David Black, Raymond Goetze
  • Method and apparatus for turbine engines
    Patent number: 8210813
    Abstract: A method for sealing a gas turbine engine includes coupling a turbine bucket to a rotor wheel and forming an interface region therebetween. A cooling air passage is defined in a portion of the rotor wheel and a cooling air manifold is defined in a portion of the turbine bucket. The method also includes inserting a seal tube within at least a portion of the cooling air passage. The method further includes coupling the cooling air passage, the seal tube, and the cooling air manifold in flow communication to at least partially define a turbine bucket cooling system. The method also includes operating the gas turbine engine such that the rotor wheel and the turbine bucket are rotated, thereby inducing a pressure on the seal tube to substantially decrease air flow discharged from the turbine bucket cooling system through the interface region.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: July 3, 2012
    Assignee: General Electric Company
    Inventor: Ian David Wilson
  • Vacuum pump
    Patent number: 8206081
    Abstract: A vacuum pump (100) comprises a pumping mechanism having an annular pumping chamber (112, 114, 116) extending about a longitudinal axis (107) and through which fluid is pumped by the pumping mechanism. A plenum (126) located remote from the pumping mechanism has an inlet (128) for receiving fluid to be pumped by the pumping mechanism and a plurality of outlets (132) arranged about the longitudinal axis (107) for supplying fluid to the annular chamber.
    Type: Grant
    Filed: October 19, 2005
    Date of Patent: June 26, 2012
    Assignee: Edwards Limited
    Inventor: Ian David Stones
  • SCROLL PUMP
    Publication number: 20120141311
    Abstract: The present application relates to a scroll compressor comprising a scroll pumping mechanism which comprises an orbiting scroll (20) having an orbiting scroll wall (34) extending axially from an orbiting scroll plate (36) towards a fixed scroll (22) and a fixed scroll having an fixed scroll wall (28) extending axially from a fixed scroll plate (30) towards the orbiting scroll. The compressor further comprises an axially extending drive shaft (14) having an eccentric shaft portion (16) so that rotation of the eccentric shaft portion imparts an orbiting motion to the orbiting scroll relative to the fixed scroll for pumping fluid from an inlet (24) to an outlet (26) of the pumping mechanism.
    Type: Application
    Filed: June 30, 2010
    Publication date: June 7, 2012
    Applicant: EDWARDS LIMITED
    Inventors: Miles Geoffery Hockliffe, Ian David Stones, Alan Ernest Kinnaird Holbrook
  • SCROLL PUMP
    Publication number: 20120134862
    Abstract: The present invention relates to a scroll pump (10) comprising two scrolls (20, 22) which are co-operable for pumping fluid from an inlet (24) to an outlet (26) on relative orbiting motion of the scrolls. Each scroll comprises a scroll base (30, 36) from which a spiral scroll wall (28, 34) extends generally axially towards the base of the opposing scroll. The pump comprises a tip seal arrangement comprising an axial end portion of one or both of the scroll walls which locates a tip seal (508) for resisting the passage of pumped fluid across the or both scroll walls between the or both scroll walls and the scroll base of the opposing scroll. The tip seal arrangement limits axial movement of the tip seal towards the scroll base of the opposing scroll along a first spiral region (507) of the or both scrolls between the inlet and the outlet.
    Type: Application
    Filed: April 9, 2010
    Publication date: May 31, 2012
    Applicant: EDWARDS LIMITED
    Inventors: Miles Geoffery Hockliffe, Ian David Stones, Alan Ernest Kinnaird Holbrook
  • MACHINE FOR BINDING REINFORCEMENT BARS
    Publication number: 20120132088
    Abstract: An apparatus for tying a wire around one or more objects such as concrete reinforcing bars is disclosed. It comprises means for passing the wire in a loop around the bars and a rotatable head for twisting the ends of the loop together. The head has at least one clamping member for clamping the wire. The clamping member provides a higher clamping force when tension in the wire is increases.
    Type: Application
    Filed: May 11, 2010
    Publication date: May 31, 2012
    Applicant: TYMATIC LIMITED
    Inventors: Graham Frank Barnes, Ian David Coles
  • VACUUM SYSTEM
    Publication number: 20120132800
    Abstract: The invention provides a vacuum system (12) comprising a plurality of vacuum chambers (14, 16, 18, 20) connected in series and a vacuum pumping arrangement (10) for differential pumping the chambers. The vacuum pumping arrangement comprises a primary pump (22) having an inlet (23) connected for pumping a first vacuum chamber (14) and an outlet (25) for exhausting at or around atmosphere, a booster pump (24) having an inlet (27) connected for pumping a second vacuum chamber (16) and an outlet (29) connected to the inlet (23) of the primary pump; and a secondary pump (26, 28) having an inlet (31, 33) connected for pumping a third vacuum chamber (18, 20) and an outlet (35, 37) connected to the inlet (27) of the booster pump.
    Type: Application
    Filed: March 30, 2010
    Publication date: May 31, 2012
    Applicant: EDWARDS LIMITED
    Inventor: Ian David Stones
  • Method and apparatus for turbine interstage seal ring
    Patent number: 8177495
    Abstract: A seal assembly for a gas turbine engine including a seal member and an interstage seal ring including an axially forward member coupled to a first radially inward surface of a first disk and an axially aft member coupled to a second radially inward surface of a second disk, wherein the seal ring is configured to move in an axial direction while the upstream and downstream arms are coupled to the first and second disk respectively.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: May 15, 2012
    Assignee: General Electric Company
    Inventors: Christopher Sean Bowes, Ian David Wilson
  • MACHINE FOR BINDING REINFORCEMENT BARS
    Publication number: 20120111206
    Abstract: A machine for forming a two-stage wire tie around a pair of bars to bind the bars together, said machine comprising means for passing said wire in a loop around the bars and a twisting head for twisting the ends of said loop together, said twisting head comprising means for gripping the ends of the wire and a tie plate through which the ends of the wire pass, and said head being resiliently mounted relative to the bars so as to allow the tie plate to move through a predetermined amount of travel towards the bars, to thereby define the length of a first stage of the tie, the machine being adapted thereafter to release the ends of the wire and continue twisting these to form a second stage of the tie.
    Type: Application
    Filed: May 5, 2010
    Publication date: May 10, 2012
    Applicant: TYMATIC LIMITED
    Inventors: Graham Frank Barnes, Ian David Coles
  • Method for congestion management of a network, a signalling protocol, a switch, an end station and a network
    Patent number: 8174978
    Abstract: A method of congestion management within a switch or network of connected switches is provided, wherein the or each of the switches has a plurality of ingress ports and a plurality of egress ports. The method involves, when congestion is detected at a first ingress or egress port, sending a message to an upstream port connected to the first ingress or egress port indicating that congestion has occurred at a particular port and requesting storage at the upstream port of data packets destined for that port; and, in dependence on the amount of data packets destined for the congested port stored at the upstream port, sending from the upstream port to a further upstream port a message informing the further upstream port of the congestion at the congested port, the further upstream port storing at the further upstream port data packets destined for the congested port.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: May 8, 2012
    Assignee: Xyratex Technology Limited
    Inventors: Finbar Naven, Ian David Johnson, Jose Duato, Jose Flich
  • METHOD FOR REDUCING METHOXYPYRAZINES IN GRAPES AND GRAPE PRODUCTS
    Publication number: 20120107467
    Abstract: The present application described a method of reducing methoxypyrazines (MPs) in grapes or grape products comprising: (a) contacting the grape or grape product with a protein that binds to MPs at a pH of about 3 to about 4 to form a protein-MP complex; and (b) removing the protein-MP complex from the grape or grape product. Also described is a method of removing MPs from samples comprising contacting the sample with a polyethersulfone membrane.
    Type: Application
    Filed: April 14, 2010
    Publication date: May 3, 2012
    Applicant: BROCK UNIVERSITY
    Inventors: Debra Inglis, Ai Lin Beh, Ian David Brindle, Gary Pickering, Eric Fabian Humes
  • Recirculating fluidic network and methods for using the same
    Patent number: 8168139
    Abstract: The present invention provides a variety of microfluidic devices and methods for conducting assays and syntheses. The devices include a solid substrate layer having a surface that is capable of attaching ligand and or anti-ligand, and an elastomeric layer attached to said surface. Preferred embodiments have deflectable membrane valves and pumps, for example, rotary pumps associated therewith.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: May 1, 2012
    Assignee: Fluidigm Corporation
    Inventors: Ian David Manger, Joseph W. Barco, Hany Ramez Nassef
  • SCROLL COMPRESSOR
    Publication number: 20120100026
    Abstract: A scroll compressor comprises two scrolls (40, 46) having respective scroll plates (42, 48) and respective scroll walls (44, 50). The scroll walls intermesh so that on relative orbital movement of the scrolls a volume (52, 54) of gas is trapped between the scrolls and pumped from an inlet (31) to an outlet (33). The axial extent (A) of said trapped volume between said scroll plates is less along a first portion (62) of a flow path (56) between the inlet and the outlet than the axial extent (B) of said trapped volume along a second portion (64) of the flow path, and wherein the first portion is closer to the inlet than the second portion along the flow path.
    Type: Application
    Filed: June 23, 2010
    Publication date: April 26, 2012
    Applicant: EDWARDS LIMITED
    Inventors: Ian David Stones, Alan Ernest Kinnaird Holbrook
  • APPARATUS AND METHOD FOR ALIGNING A TURBINE CASING
    Publication number: 20120093639
    Abstract: A casing includes an inner shell and an outer shell that surrounds the inner shell and comprises a plurality of inflection points. An annular flange is between the inner shell and the outer shell, and a plurality of joints attach the inner shell to the annular flange. A connector is between the annular flange and the outer shell at each of the plurality of inflection points. A method for assembling a casing includes joining a plurality of curved sections to one another to generally define an arcuate inner shell and surrounding the arcuate inner shell with an outer shell. The method further includes attaching the arcuate inner shell to an annular flange at first attachment points and connecting the annular flange to the outer shell at second attachment points spaced approximately equidistantly from the first attachment points.
    Type: Application
    Filed: October 13, 2010
    Publication date: April 19, 2012
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Henry Grady Ballard, JR., Ian David Wilson, Martel Alexander McCallum, Stephen Christopher Chieco, Kenneth Damon Black, Christopher Paul Cox
  • Driving and steering of motor vehicles
    Patent number: 8157030
    Abstract: An arrangement and a method are disclosed for driving and steering an engine driven vehicle of the type m which left and right hand wheels 120L, 120R are respectively driven from the engine through left and right hand transmissions 122L, 122R and a steering effect is exerted by changing the ratio of one transmission relative to the other. According to the invention a follower is operatively coupled to at least one of the transmissions and is movable circumferentially about an axis by means of a driver actuable steering control to change the relative speeds of the two driven wheels and radially with respect to the axis by means of a driver actuable speed control to increase/decrease the speeds of the two driven wheels in unison.
    Type: Grant
    Filed: August 18, 2006
    Date of Patent: April 17, 2012
    Assignee: MTD Products Inc
    Inventors: Christopher John Greenwood, Ian David Cornwell
  • Ball piston steering devices and methods of use
    Patent number: 8157024
    Abstract: Embodiments include ball piston steering devices and methods for use of ball piston devices. In one aspect a ball piston steering device includes a sleeve in fluid communication with a fluid source and a ball received within the sleeve. The ball is movable within the sleeve between a recessed position and an extended position.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: April 17, 2012
    Assignee: Schlumberger Technology Corporation
    Inventors: Fabio de Paula Neves, Alexander Slocum, Ian David Thomas
  • MEDICAL SECURING DEVICE
    Publication number: 20120085352
    Abstract: A medical securing device (1) comprising a flexible strap (2) including a longitudinal slot (4) proximal to a transversely narrow bridge section (3) disposed between distal end portions (6, 7), wherein the end portions are connectable to a medical neckband.
    Type: Application
    Filed: June 18, 2009
    Publication date: April 12, 2012
    Applicant: Kapitex Healthcare Limited
    Inventor: Ian David Worthington