Patents by Inventor Ian Duncan
Ian Duncan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20250250613Abstract: The subject invention pertains to a method for identifying G-quadruplexes (G4s) in a cell using a G4 fluorescent probe, 2-(2-hydroxy-6-methoxy-3-propionylphenyl)quinazolin-4(3H)-one (HMPQ), which exhibits specific binding affinity to G-quadruplexes (G4s), illuminating these non-canonical nucleic acid structures without altering their conformation. G4s are involved in chromatin organisation, gene regulation, genome stability, and appear to contribute to cancer growth and progression. By utilizing HMPQ's unique fluorescence mechanism through excited-state intramolecular proton transfer, the method allows label-free precise detection of G4 structures in the nucleus of a cell.Type: ApplicationFiled: February 7, 2025Publication date: August 7, 2025Inventors: Pei-Yuan QIAN, Wenkang YE, Ben Zhong TANG, Xinnan WANG, Changdong LIU, Ching SUEN, Guang ZHU, Ian Duncan WILLIAMS, Parvej ALAM
-
Publication number: 20250236149Abstract: A suspension system of a vehicle can provide configurable stiffness and damping characteristics. The system can include a plurality of shock absorbers, one or more valve assemblies, and a plurality of accumulators. The plurality of shock absorbers, which can be synchronous or non-synchronous, each correspond to a respective wheel of a vehicle. The valve assembly is configured for controlling hydraulic fluid in the plurality of shock absorbers to achieve a plurality of suspension modes affecting bounce, pitch, roll, and warp. The valve assemblies can be controlled to manage pitch stiffness of the vehicle in response to detected conditions, such as longitudinal and lateral dynamics, with overrides in response to vertical acceleration and/or damper displacement. Accordingly, the handling improvement provided by varying suspension modes is balanced with a desire to provide improved ride characteristics.Type: ApplicationFiled: January 22, 2024Publication date: July 24, 2025Inventors: Fabio BUSNELLI, Andrea DAMIANI, Ian DUNCAN, JR.
-
Publication number: 20250136577Abstract: The present invention relates to compounds that are MALT1 inhibitors. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with MALT1.Type: ApplicationFiled: February 3, 2023Publication date: May 1, 2025Inventors: Ian Duncan Linney, Nicholas Charles Ray, Martin John Watson, Paul Matthew Blaney, Oliver Thomas Kern, Simon Osborne, Martin Amber, Chido Mpamhanga
-
Publication number: 20250091188Abstract: A power tool includes a housing having a motor housing portion and a handle portion extending therefrom. An electric motor is positioned within the motor housing portion. The power tool also includes trigger switch configured to activate and deactivate the motor. The power tool further includes a non-contact mode selector switch that is separate from the trigger switch and configured to adjust an operational mode of the tool. The non-contact mode selector switch is positioned in a foot of the handle portion opposite the motor housing portion.Type: ApplicationFiled: December 3, 2024Publication date: March 20, 2025Inventors: Maxwell L. Merget, Jingyuan Liang, Michael R. Sande, Michael Halverson, Ian Duncan, Nicholas C. Mantych, Alex Huber
-
Patent number: 12208501Abstract: A rotary power tool includes a housing having a motor housing portion and a handle portion extending therefrom. An electric motor is positioned within the motor housing portion. The rotary power tool further includes a trigger switch configured to activate and deactivate the motor. The rotary power tool further includes a non-contact speed selector switch that is separate from the trigger switch and configured to adjust a rotational speed of the motor. The non-contact speed selector switch is positioned in a foot of the handle portion opposite the motor housing portion.Type: GrantFiled: September 5, 2023Date of Patent: January 28, 2025Assignee: MILWAUKEE ELECTRIC TOOL CORPORATIONInventors: Maxwell L. Merget, Jingyuan Liang, Michael R. Sande, Michael Halverson, Ian Duncan, Nicholas C. Mantych, Alex Huber
-
Publication number: 20240416495Abstract: A power tool includes a drive mechanism including an electric motor, a housing, and a spindle rotatable about a longitudinal axis in response to the drive mechanism. The power tool further includes a lockout mechanism including a plurality of detents asymmetrically positioned around the longitudinal axis, where each of the detents are movable between a locking position and an unlocking position. The power tool also includes a collar rotatably coupled to the housing, the collar including a plurality of recesses asymmetrically positioned around the longitudinal axis, wherein in the unlocking position, each of the detents is received in one of the recesses and the spindle is axially movable within the housing, and wherein in the locking position, at least one of the detents is not received in one of the recesses and axial movement of the spindle is prevented by the lockout mechanism.Type: ApplicationFiled: August 26, 2024Publication date: December 19, 2024Inventors: Ian Duncan, Ryan A. Dedrickson
-
Publication number: 20240414104Abstract: A modular network element includes a plurality of modules each comprising a plurality of faceplate ports connected to fabric circuitry configured to perform Ethernet switching; and a cabled backplane providing connectivity between the plurality of modules, the cabled backplane includes each module of the plurality of modules having a set of the plurality of faceplate ports interconnected to other modules of the plurality of modules.Type: ApplicationFiled: August 20, 2024Publication date: December 12, 2024Applicant: Ciena CorporationInventors: Daniel Rivaud, Ian Duncan, Anthony J. Mayenburg, James Tierney, Simon J. E. Shearman
-
Patent number: 12107775Abstract: A modular network element includes one or more lineboxes which are a hybrid between a rack mounted module and a line module which is inserted in a chassis; one or more linebox carriers which are rack mountable and configured to selectively receive the one or more lineboxes and provide power connectors and data connectors thereto; and a core chassis including one or more switch modules, one or more controller modules, and a set of connectors located at the rear for cabling to the power connectors and the data connectors on the one or more linebox carriers.Type: GrantFiled: April 23, 2018Date of Patent: October 1, 2024Assignee: Ciena CorporationInventors: Daniel Rivaud, Ian Duncan, Anthony J. Mayenburg, James Tierney, Simon J. E. Shearman
-
Patent number: 12083661Abstract: A hammer drill comprises a drive mechanism including a spindle, a first ratchet coupled for co-rotation with the spindle, a second ratchet rotationally fixed to the housing, and a hammer lockout mechanism adjustable between a first mode and a second mode. The hammer drill further comprises a clutch adjustable between a first mode and a second mode. The hammer drill further comprises a detent radially movable between a locking position and an unlocking position, and a collar movable between a first rotational position in which the hammer lockout mechanism is in the first mode and a second rotational position in which the hammer lockout mechanism is in the second mode. In the first mode the detent is positioned such that the spindle is moveable relative to the housing. In the second mode the detent is positioned such that the spindle is prevented from moving relative to the housing.Type: GrantFiled: August 24, 2022Date of Patent: September 10, 2024Assignee: MILWAUKEE ELECTRIC TOOL CORPORATIONInventors: Ian Duncan, Ryan A. Dedrickson
-
Patent number: 11897110Abstract: A rotary power tool includes a housing having a motor housing portion and a handle portion extending therefrom. An electric motor is positioned within the motor housing portion. The rotary power tool further includes a trigger switch configured to activate and deactivate the motor. The rotary power tool further includes a non-contact speed selector switch positioned in the housing. The non-contact speed selector switch is configured to adjust a rotational speed of the motor. The non-contact speed selector switch is separate from the trigger switch.Type: GrantFiled: November 1, 2018Date of Patent: February 13, 2024Assignee: MILWAUKEE ELECTRIC TOOL CORPORATIONInventors: Maxwell L. Merget, Jingyuan Liang, Michael R. Sande, Michael Halverson, Ian Duncan, Nicholas C. Mantych, Alex Huber
-
Publication number: 20230405786Abstract: A rotary power tool includes a housing having a motor housing portion and a handle portion extending therefrom. An electric motor is positioned within the motor housing portion. The rotary power tool further includes a trigger switch configured to activate and deactivate the motor. The rotary power tool further includes a non-contact speed selector switch that is separate from the trigger switch and configured to adjust a rotational speed of the motor. The non-contact speed selector switch is positioned in a foot of the handle portion opposite the motor housing portion.Type: ApplicationFiled: September 5, 2023Publication date: December 21, 2023Inventors: Maxwell L. Merget, Jingyuan Liang, Michael R. Sande, Michael Halverson, Ian Duncan, Nicholas C. Mantych, Alex Huber
-
Patent number: 11583988Abstract: A hammer drill comprises a drive mechanism including a spindle, a first ratchet coupled for co-rotation with the spindle, a second ratchet rotationally fixed to the housing, and a hammer lockout mechanism adjustable between a first mode and a second mode. The hammer drill further comprises a clutch adjustable between a first state and a second state. The hammer drill further comprises a collar rotatably coupled to the housing and movable between a first rotational position in which the hammer lockout mechanism is in the first mode and the clutch is in the first state, a second rotational position in which the hammer lockout mechanism is in the second mode and the clutch is in the first state, and a third rotational position in which the hammer lockout mechanism is in the second mode and the clutch is in the second state.Type: GrantFiled: July 7, 2020Date of Patent: February 21, 2023Assignee: MILWAUKEE ELECTRIC TOOL CORPORATIONInventors: Ian Duncan, Ryan A. Dedrickson
-
Publication number: 20220410359Abstract: A hammer drill comprises a drive mechanism including a spindle, a first ratchet coupled for co-rotation with the spindle, a second ratchet rotationally fixed to the housing, and a hammer lockout mechanism adjustable between a first mode and a second mode. The hammer drill further comprises a clutch adjustable between a first mode and a second mode. The hammer drill further comprises a detent radially movable between a locking position and an unlocking position, and a collar movable between a first rotational position in which the hammer lockout mechanism is in the first mode and a second rotational position in which the hammer lockout mechanism is in the second mode. In the first mode the detent is positioned such that the spindle is moveable relative to the housing. In the second mode the detent is positioned such that the spindle is prevented from moving relative to the housing.Type: ApplicationFiled: August 24, 2022Publication date: December 29, 2022Inventors: Ian Duncan, Ryan A. Dedrickson
-
Patent number: 11469645Abstract: A power tool includes an electric motor having an output shaft, a transmission having a transmission housing, a spindle rotatable in response to receiving torque from the transmission and a pinion coupled to the output shaft. The pinion includes a bushing portion, a toothed portion for driving the transmission, and a cylindrical portion between the bushing portion and the toothed portion. The power tool further comprises a fan coupled to the bushing portion of the pinion and a bearing arranged between the cylindrical portion and the transmission housing for rotatably supporting the pinion and the output shaft.Type: GrantFiled: January 21, 2019Date of Patent: October 11, 2022Assignee: MILWAUKEE ELECTRIC TOOL CORPORATIONInventors: Ryan A. Dedrickson, Ian Duncan, Timothy R. Reichert
-
Patent number: 11426852Abstract: A hammer drill comprises a drive mechanism including a spindle, a first ratchet coupled for co-rotation with the spindle, a second ratchet rotationally fixed to the housing, and a hammer lockout mechanism adjustable between a first mode and a second mode. The hammer drill further comprises a clutch adjustable between a first mode and a second mode. The hammer drill further comprises a detent radially movable between a locking position and an unlocking position, and a collar movable between a first rotational position in which the hammer lockout mechanism is in the first mode and a second rotational position in which the hammer lockout mechanism is in the second mode. In the first mode the detent is positioned such that the spindle is moveable relative to the housing. In the second mode the detent is positioned such that the spindle is prevented from moving relative to the housing.Type: GrantFiled: September 22, 2021Date of Patent: August 30, 2022Assignee: MILWAUKEE ELECTRIC TOOL CORPORATIONInventors: Ian Duncan, Ryan A. Dedrickson
-
Patent number: 11271868Abstract: Programmable switches and routers are described herein for enabling their internal network fabric to be configured with a topology. In one implementation, a programmable switch is arranged in a network having a plurality of switches and an internal fabric. The programmable switch includes a plurality of programmable interfaces and a buffer memory component. Also, the programmable switch includes a processing component configured to establish each of the plurality of programmable interfaces to operate as one of a user-facing interface and a fabric-facing interface. Based on one or more programmable interfaces being established as one or more fabric-facing interfaces, the buffer memory component is configured to store packets received from a user-facing interface of an interconnected switch of the plurality of switches via one or more hops into the internal fabric.Type: GrantFiled: July 28, 2020Date of Patent: March 8, 2022Assignee: Ciena CorporationInventors: Michael Y. Frankel, Vladimir Pelekhaty, Daniel Rivaud, Ian Duncan
-
Publication number: 20220038391Abstract: Programmable switches and routers are described herein for enabling their internal network fabric to be configured with a topology. In one implementation, a programmable switch is arranged in a network having a plurality of switches and an internal fabric. The programmable switch includes a plurality of programmable interfaces and a buffer memory component. Also, the programmable switch includes a processing component configured to establish each of the plurality of programmable interfaces to operate as one of a user-facing interface and a fabric-facing interface. Based on one or more programmable interfaces being established as one or more fabric-facing interfaces, the buffer memory component is configured to store packets received from a user-facing interface of an interconnected switch of the plurality of switches via one or more hops into the internal fabric.Type: ApplicationFiled: July 28, 2020Publication date: February 3, 2022Inventors: Michael Y. Frankel, Vladimir Pelekhaty, Daniel Rivaud, Ian Duncan
-
Publication number: 20220001522Abstract: A hammer drill comprises a drive mechanism including a spindle, a first ratchet coupled for co-rotation with the spindle, a second ratchet rotationally fixed to the housing, and a hammer lockout mechanism adjustable between a first mode and a second mode. The hammer drill further comprises a clutch adjustable between a first mode and a second mode. The hammer drill further comprises a detent radially movable between a locking position and an unlocking position, and a collar movable between a first rotational position in which the hammer lockout mechanism is in the first mode and a second rotational position in which the hammer lockout mechanism is in the second mode. In the first mode the detent is positioned such that the spindle is moveable relative to the housing. In the second mode the detent is positioned such that the spindle is prevented from moving relative to the housing.Type: ApplicationFiled: September 22, 2021Publication date: January 6, 2022Inventors: Ian Duncan, Ryan A. Dedrickson
-
Patent number: 10924324Abstract: Systems and methods of managing a modular network element as a single entity and the modular network element includes a plurality of line modules and zero or more switch modules in a chassis. The plurality of line modules are located separate from the chassis and connected to the chassis and/or to one another via cabling. The method includes operating a management plane between the plurality of line modules and the zero or more switch modules via one or more dedicated links in the cabling; managing the plurality of line modules and the zero or more switch modules as a single network element utilizing a chassis management protocol over the management plane; and designating one of a controller in the chassis and a processor in one of the plurality of line modules operating as a virtual controller as primary for the chassis management protocol.Type: GrantFiled: April 23, 2018Date of Patent: February 16, 2021Assignee: Ciena CorporationInventors: Daniel Rivaud, Ian Duncan, Anthony J. Mayenburg, James Tierney, Simon J. E. Shearman
-
Publication number: 20200331136Abstract: A hammer drill comprises a drive mechanism including a spindle, a first ratchet coupled for co-rotation with the spindle, a second ratchet rotationally fixed to the housing, and a hammer lockout mechanism adjustable between a first mode and a second mode. The hammer drill further comprises a clutch adjustable between a first state and a second state. The hammer drill further comprises a collar rotatably coupled to the housing and movable between a first rotational position in which the hammer lockout mechanism is in the first mode and the clutch is in the first state, a second rotational position in which the hammer lockout mechanism is in the second mode and the clutch is in the first state, and a third rotational position in which the hammer lockout mechanism is in the second mode and the clutch is in the second state.Type: ApplicationFiled: July 7, 2020Publication date: October 22, 2020Inventors: Ian Duncan, Ryan A. Dedrickson