Patents by Inventor Ian George
Ian George has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6406878Abstract: A method for identifying an inhibitor of dehydroquinate synthase (DHQS) and/or dehydroquinase (DQ), which method comprises: i) contacting a test substance with DHQS and a substrate for DHQS and contacting the resulting reaction mixture with DQ, or contacting the test substance with DQ and a substrate for DQ; and ii) contacting the resulting reaction mixture with dehydroshikimate dehydratase (DHSD); and iii) determining whether the test substance inhibits the activity of DHQS or DQ.Type: GrantFiled: March 2, 2001Date of Patent: June 18, 2002Assignee: Arrow Therapeutics LimitedInventors: Alastair Robert Hawkins, Heather Kim Lamb, Ian George Charles
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Patent number: 6384788Abstract: An antenna comprises a metal sheet (12), an array of radiator elements (14) on the upper side of the metal sheet, and a stripline feed (20) for the radiator elements on the lower side of the metal sheet. The metal sheet is shaped to have first portions (12.1) which are at a low level, a second portion (12.2) which is at a high level, and intermediate portions (12.3) which join the second portion to the first portions, thereby forming a channel in the underside of the metal sheet, the channel being between a pair of the radiator elements. The stripline feed is in the channel, at a level which is higher than that of the upwardly facing surfaces of the first portions. The first portions form a ground plane for the radiator elements, and the second portion forms an upper ground plane for the stripline feed. The lower ground plane of the stripline feed is formed by a sheet of metal foil (24) which extends across the channel.Type: GrantFiled: April 5, 2001Date of Patent: May 7, 2002Assignee: Omnipless (Proprietary) LimitedInventors: Johannes Arnoldus Pretorius, William Ian George, Marius Du Plessis
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Patent number: 6378559Abstract: A discharge flow control includes a plurality of flexible elongate elements adapted to be supported at one end from a discharge outlet to extend from the outlet in the direction of the discharge and across the flow path of the discharge outlet.Type: GrantFiled: October 13, 2000Date of Patent: April 30, 2002Inventor: Ian George Humphryson
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Patent number: 6372774Abstract: N-Phenylpyrazole derivatives of the formula: wherein R1 represents optionally halogenated alkyl; R2 represents halogen, cyano, nitro, cycloalkyl, alkenyl, thiocyanato, optionally alkyl substituted sulphamoyl, optionally alkyl substituted carbamoyl, alkoxycarbonyl, alkanoyl or optionally halogenated alkyl; and R3 represents a hydrogen atom or a group N″R′″ or a variety of other groupings. These compounds possess arthropodicidal, plant nematocidal, anthelmintic and anti-protozoal properties; their preparation, compositions containing them and their use are described.Type: GrantFiled: July 16, 1999Date of Patent: April 16, 2002Assignee: Rhone-Poulenc Agriculture Ltd.Inventors: Leslie Roy Hatton, Ian George Buntain, David William Hawkins, Edgar William Parnell, Christopher John Pearson, David Alan Roberts
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Publication number: 20020002122Abstract: This invention relates to lubricant compositions comprising a polyalkylene glycol and an ester wherein the polyalkylene glycol has the formula:Type: ApplicationFiled: April 27, 2001Publication date: January 3, 2002Inventors: Mitchell Corner, Peter Timothy Gibb, Steven James Randles, Robert Ian George Thompson
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Publication number: 20010028325Abstract: An antenna comprises a conductive foil layer (16) which forms a ground plane, a conductive foil element (20) spaced from the ground plane, and a dielectric substrate (14) separating the foil element from the ground plane, the dielectric substrate being of an extruded plastics material having a cellular configuration in cross-section. More particularly, the dielectric substrate comprises one or more superimposed substrate sheets of extruded plastics material, with the or each substrate sheet comprising a pair of spaced, parallel skins (38) and webs (40) extending between and separating the skins. A method of applying the foil element to the dielectric substrate and of making the antenna and various component parts thereof are also disclosed.Type: ApplicationFiled: April 5, 2001Publication date: October 11, 2001Inventors: Johannes Arnoldus Pretorius, William Ian George, Marius Du Plessis
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Publication number: 20010028326Abstract: An antenna comprises a metal sheet (12), an array of radiator elements (14) on the upper side of the metal sheet, and a stripline feed (20) for the radiator elements on the lower side of the metal sheet. The metal sheet is shaped to have first portions (12.1) which are at a low level, a second portion (12.2) which is at a high level, and intermediate portions (12.3) which join the second portion to the first portions, thereby forming a channel in the underside of the metal sheet, the channel being between a pair of the radiator elements. The stripline feed is in the channel, at a level which is higher than that of the upwardly facing surfaces of the first portions. The first portions form a ground plane for the radiator elements, and the second portion forms an upper ground plane for the stripline feed. The lower ground plane of the stripline feed is formed by a sheet of metal foil (24) which extends across the channel.Type: ApplicationFiled: April 5, 2001Publication date: October 11, 2001Inventors: Johannes Arnoldus Pretorius, William Ian George, Marius Du Plessis
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Patent number: 6172279Abstract: Male sterility is imparted to a plant by a cascade of gene sequences which expresses a protein which disrupts the biosynthesis of viable pollen. Expression of the disrupter protein is restricted to male parts of the plant by an upstream promoter sequence which is specific to male flowers, the male specific promoter being under control of an operator sequence. The cascade also includes a gene encoding a repressor protein specific for that operator. Expression of the repressor protein is under control of a chemically inducible promoter which is inducible by the application to the plant by, spraying or like process, of an exogenous chemical. In the absence of the exogenous chemical inducer, no repressor protein is expressed, resulting in expression of the disrupter protein and, consequently, male sterility.Type: GrantFiled: November 7, 1995Date of Patent: January 9, 2001Assignee: Zeneca LimitedInventors: Ian George Bridges, Simon William Jonathan Bright, Andrew James Greenland, Wolfgang Walter Schuch
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Patent number: 6162916Abstract: A process for preparing agrochemical intermediates of formula (I), wherein W is (CH.sub.3 O).sub.2 CH.CHCO.sub.2 CH.sub.3 or CH.sub.3 O.CH.dbd.CCO.sub.2 CH.sub.3 ; Z.sup.1 is a halogen atom; and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are independently hydrogen, halogen, C.sub.1-4 alky, C alkoxy, acetoxy or acyl; the process comprising the steps of: (a) reacting a compound of formula (II), wherein X, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined above, with a compound of formula ROCH.sub.3, wherein R is a metal; and, (b) reacting the product of (a) with a compound of formula (III), wherein Z.sup.1 and Z.sup.2 are halogen atoms. A process for the preparation of compounds of formula (II) and compounds of formula (II) themselves. A process for obtaining, in substantially pure form, a compound of formula (11) and compounds of formula (II) themselves. A process for obtaining, in substantially pure form, a compound of formula (11) wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are all hydrogen.Type: GrantFiled: February 16, 1999Date of Patent: December 19, 2000Assignee: Zeneca LimitedInventors: Alan John Whitton, Brian Geoffrey Cox, Gareth Andrew De Boos, Ian Gordon Berry, Ian George Fleming, Raymond Vincent Heavon Jones
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Patent number: 6153750Abstract: A process for preparing (E)-methyl 2-[2-(6-(-cyanophenoxy)pyrimidin-4-yloxy)phenyl]-3-methoxypropenoate comprising contacting (E)-methyl 2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3-methoxypropenoate or methyl 2-[2-(6-chloropyrimidin-4-yloxy)phenyl]-3,3-dimethoxypropanoate with 2-cyanophenate anions, the process being conducted in the absence of copper or a copper salt and in the absence of N,N-dimethylformamide. The 2-cyanophenate anions are generated in situ by reacting 2-cyanophenol with an alkali metal carbonate.Type: GrantFiled: June 10, 1999Date of Patent: November 28, 2000Assignee: ZENECA LimitedInventors: Alan John Whitton, Ian George Fleming, Robert Comgall Ewins, Raymond Vincent Heavon Jones, Samuel McNeish
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Patent number: 6066456Abstract: The chemically-inducible 27 kD subunit of the enzyme glutathione-S-transferase, isoform II (GST-II-27) and sequences encoding it are provided. In particular, a genomic DNA sequence encoding the gene promoter for the GST-II-27 subunit is provided. Then linked to an exogenous gene and introduced into a plant by transformation, and GST-II-27 promoter provides a means for the external regulation of expression of that exogenous gene. Transformation with DNA encoding glutathione-S-transferase polypeptides produces herbicide resistance transgenic plants.Type: GrantFiled: March 26, 1998Date of Patent: May 23, 2000Assignee: Zeneca LimitedInventors: Ian George Bridges, Simon William Jonathan Bright, Andrew James Greenland, David Charles Holt, Ian Jepson, Wolfgang Walter Schuch
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Patent number: 6010887Abstract: Pseudo-operator sequences may be located in (or inserted into) plant genomes and utilized to drive expression of foreign genes. These pseudo-operator sequences are nucleotide sequences which are present at a suitable location in a gene at which repressor binding will lead to inhibitation or enhancement of gene expression. The disclosed technique permits the design of altered specificity repressors, which bind the pseudo-operators.Type: GrantFiled: September 14, 1994Date of Patent: January 4, 2000Assignees: Imperial Chemical Industries PLC, University of LeicesterInventors: Ian George Bridges, Simon William Jonathan Bright, Andrew James Greenland, Wolfgang Walter Schuch, Andrew Merryweather, David Pioli
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Patent number: 5985779Abstract: Disclosed is a quartz glass product of enhanced opacity manufactured by fusion of silica particles, the opacity being enhanced by the reaction of an organosilicon additive in the course of the fusion process. A method of enhancing the opacity of a quart glass product by fusing silica particles in the presence of an organosilicon additive is also disclosed.Type: GrantFiled: August 13, 1998Date of Patent: November 16, 1999Assignee: TSL Group PLCInventors: Ian George Sayce, Peter John Wells
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Patent number: 5980907Abstract: Attenuated microorganism for use in immunoprophylaxis in which the attenuation is brought about by the presence of a mutation in the DNA sequence of the microorganism which encodes, or which regulates the expression of DNA encoding a protein that is produced in response to environmental stress, the microorganism optionally being capable of expressing DNA encoding a heterologous antigen.Type: GrantFiled: June 5, 1995Date of Patent: November 9, 1999Assignee: Glaxo Wellcome Inc.Inventors: Gordan Dougan, Ian George Charles, Carlos Estenio Hormaeche, Kevin Stuart Johnson, Steven Neville Chatfield
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Patent number: 5976544Abstract: A polypeptide for use in a vaccine against Bordetella pertussis, B. parapertussis or B. bronchiseptica contains an epitope selected from (a) the amino acid sequence coded for by nucleotides 1885 to 1902 of the P.69 gene of B. pertussis CN2992; (b) the corresponding amino acid sequence of another strain of B. pertussis or of a strain of B.parapertussis or B. bronchiseptica; and (c) a modified version of sequence (a) or (b) which has substantially the same antigenicity. The polypeptide is no more than 50 amino acid residues long or is a chimaeric protein composed of a carrier protein sequence and a sequence of no more than 50 amino acid residues which contains the required epitope.Type: GrantFiled: June 7, 1995Date of Patent: November 2, 1999Assignee: Medeva Pharma LimitedInventors: Ian George Charles, Neti Fraser Fairweather
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Patent number: 5916618Abstract: N-Phenylpyrazole derivatives of the formula: ##STR1## wherein R.sup.1 represents cyano, nitro, halogen, acetyl or formyl; R.sup.2 represents R.sup.5 SO.sub.2, R.sup.5 SO or R.sup.5 S in which R.sup.5 is optionally halogen substituted alkyl, alkenyl or alkynyl;R.sup.3 represents a hydrogen atom or a group NR.sup.6 R.sup.7 wherein R.sup.6 and R.sup.7 each represent hydrogen, alkyl, alkenylalkyl, alkynylalkyl, formyl, optionally halogen substituted alkanoyl, optionally halogen substituted alkoxycarbonyl, or alkoxymethyleneamino, halogen, or R.sup.6 and R.sup.7 together form a cyclic imide and R.sup.4 represents a substituted phenyl group possess arthropodicidal, plant nematocidal, anthelmintic and anti-protozoal properties; their preparation, compositions containing them and their use are described.Type: GrantFiled: October 7, 1997Date of Patent: June 29, 1999Assignee: Rhone-Poulenc Agriculture Ltd.Inventors: Leslie Roy Hatton, Ian George Buntain, David William Hawkins, Edgar William Parnell, Christopher John Pearson, David Alan Roberts
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Patent number: 5866792Abstract: The chemically-inducible 27 kD subunit of the enzyme glutathione-S-transferase, isoform II (GST-II-27) and sequences encoding it are provided. In particular, a genomic DNA sequence encoding the gene promoter for the GST-II-27 subunit is provided. Then linked to an exogenous gene and introduced into a plant by transformation, and GST-II-27 promoter provides a means for the external regulation of expression of that exogenous gene. Transformation with DNA encoding glutathione-S-transferase polypeptides produces herbicide resistance transgenic plants.Type: GrantFiled: June 17, 1996Date of Patent: February 2, 1999Assignee: Zeneca LimitedInventors: Ian George Bridges, Simon William Jonathan Bright, Andrew James Greenland, David Charles Holt, Ian Jepson, Wolfgang Walter Schuch
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Patent number: 5858375Abstract: A pharmaceutical composition comprises a solution or suspension of a biological agent in a diluent comprising D.sub.2 O, which solution or suspension contains sufficient amounts of a sugar, phosphate, glutamic acid or a physiologically acceptable salt thereof and, optionally, a non-toxic protein, a peptone or a mixture of two or more amino acids besides glutamic acid to enhance the stability of the agent. Typically, the composition is a suspension of a live attenuated poliovirus or an inactivated poliovirus of each of poliovirus types 1, 2 and 3. Preferably the solution or suspension contains stabilising amounts of sucrose, KH.sub.2 PO.sub.4, K.sub.2 HPO.sub.4, L-glutamic acid or sodium glutamate and human serum albumin (SPGA).Type: GrantFiled: May 21, 1997Date of Patent: January 12, 1999Assignee: Medeva Europe LimitedInventors: Ian George Stephen Furminger, Philip James Sizer
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Patent number: 5848385Abstract: Source language text from an input interface is broken down into source language morphemes by a morphological analyzer. A syntactic analyzer converts the morphemes into source language signs labelled with identifiers and data identifying other signs which are grammatically related. A bilingual equivalence transformer transforms the source language signs to target language signs which are combined by a combiner to provide a first attempt at a target language structure. The structure is repeatedly evaluated by an evaluator and transformed by a transformer. The signs of well formed substructures identified by the evaluator are not dissociated from each other by the transformer. This process ends when either the whole target language structure is evaluated as being well formed or all transformations have been unsuccessfully evaluated.Type: GrantFiled: November 27, 1995Date of Patent: December 8, 1998Assignee: Sharp Kabushiki KaishaInventors: Victor Poznanski, John Luis Beaven, Ian George Johnson
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Patent number: D463299Type: GrantFiled: January 18, 2002Date of Patent: September 24, 2002Assignee: Siemens Milltronics Process Instruments Inc.Inventor: Ian George Watson