Patents by Inventor Ian Harding

Ian Harding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10288577
    Abstract: A test strip with an incorporated optical waveguide and deflectors punched through the optical waveguide allows light to exit through a layer of the test strip and be detected by a photo detector. Using light and a photodetector, these uniquely coded strips are identified. The waveguide can be constructed by sandwiching two layers of the test strip around a light transmissible layer. This configuration allows light to be transmitted through the test strip and out the other end, as well as allowing some light to escape the deflector. This light is detected by a photodetector mounted in the analyte test meter. The deflectors may be placed in patterns such that detection of this light indicates certain characteristics of the strip, such as non-counterfeit, regional identification, type of analyte tested, and coding information.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: May 14, 2019
    Assignee: AgaMatrix, Inc.
    Inventors: Sridhar Iyengar, Ian Harding, Charles Boiteau, Colin Butters
  • Patent number: 10285633
    Abstract: Correction for initial variation in thickness of a polymer layer and for changes in the coating thickness that occur after implantation of a biosensor and therefore provides substantial increase in the accuracy and lifetime of implantable sensors is done using a factor derived from the decay of potential.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: May 14, 2019
    Assignee: AgaMatrix, Inc.
    Inventors: Sridhar Iyengar, Ian Harding
  • Publication number: 20190113498
    Abstract: A method for obtaining information encoded on an electrochemical test strip is provided. The test strip has two electrodes disposed within a sample space and the information is encoded on the test strip prior to introduction of liquid sample. The method includes the step of introducing sample to the sample space so that the sample is in contact with the two electrodes within the sample space. In another step a value is determined that is representative of the double layer capacitance of the test strip and/or the equivalent capacitance of the test strip. The determined value is then translated into information reflecting a characteristic of the test strip prior to introduction of sample.
    Type: Application
    Filed: December 17, 2018
    Publication date: April 18, 2019
    Applicant: AgaMatrix, Inc.
    Inventors: Sridhar Iyengar, Ian Harding, Richard Williams, Kevin Cai
  • Patent number: 10203298
    Abstract: Electrochemical test cells are made with precision and accuracy by adhering an electrically resistive sheet having a bound opening to a first electrically conductive sheet. A notching opening is then punched through the electrically resistive sheet and the first electrically conductive sheet. The notching opening intersects the first bound opening in the electrically resistive sheet, and transforms the first bound opening into a notch in the electrically resistive sheet. A second electrically conductive sheet is punched to have a notching opening corresponding to that of first electrically conductive sheet, and this is adhered to the other side of the electrically resistive sheet such that the notching openings are aligned. This structure is cleaved from surrounding material to form an electrochemical cell that has a sample space for receiving a sample defined by the first and second conductive sheets and the notch in the electrically resistive sheet.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: February 12, 2019
    Assignee: AgaMatrix, Inc.
    Inventors: Ian Harding, Sridhar G. Iyengar
  • Patent number: 10168313
    Abstract: A method for obtaining information encoded on an electrochemical test strip is provided. The test strip has two electrodes disposed within a sample space and the information is encoded on the test strip prior to introduction of liquid sample. The method includes the step of introducing sample to the sample space so that the sample is in contact with the two electrodes within the sample space. In another step a value is determined that is representative of the double layer capacitance of the test strip and/or the equivalent capacitance of the test strip. The determined value is then translated into information reflecting a characteristic of the test strip prior to introduction of sample.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 1, 2019
    Assignee: AgaMatrix, Inc.
    Inventors: Sridhar Iyengar, Ian Harding, Richard Williams, Kevin Cai
  • Publication number: 20180249938
    Abstract: Correction for initial variation in thickness of a polymer layer and for changes in the coating thickness that occur after implantation of a biosensor and therefore provides substantial increase in the accuracy and lifetime of implantable sensors is done using a factor derived from the decay of potential.
    Type: Application
    Filed: March 2, 2018
    Publication date: September 6, 2018
    Applicant: AgaMatrix, Inc.
    Inventors: Sridhar Iyengar, Ian Harding
  • Publication number: 20180231552
    Abstract: A method and apparatus for electrochemical detection of analyte in a sample makes use of a binding interaction and relies on the discovery that asymmetric distribution of a redox enzyme between two electrodes that occurs when a redox enzyme-containing reagent is immobilized at the surface of one electrode can be detected as a chemical potential gradient arising from an asymmetry in the distribution of oxidized or reduced redox substrate. This chemical potential gradient can be detected potentiometrically by observing the potential difference between the electrodes in an open circuit, or amperometrically by observing the current flow between the electrodes when the circuit is closed. In both cases, the observation of asymmetry can be done without the application of an external potential or current to the electrodes.
    Type: Application
    Filed: April 3, 2018
    Publication date: August 16, 2018
    Applicant: AgaMatrix, Inc.
    Inventors: Ian Harding, Sridhar Iyengar, Richard Williams
  • Patent number: 9939440
    Abstract: A method and apparatus for electrochemical detection of analyte in a sample makes use of a binding interaction and relies on the discovery that asymmetric distribution of a redox enzyme between two electrodes that occurs when a redox enzyme-containing reagent is immobilized at the surface of one electrode can be detected as a chemical potential gradient arising from an asymmetry in the distribution of oxidized or reduced redox substrate. This chemical potential gradient can be detected potentiometrically by observing the potential difference between the electrodes in an open circuit, or amperometrically by observing the current flow between the electrodes when the circuit is closed. In both cases, the observation of asymmetry can be done without the application of an external potential or current to the electrodes.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: April 10, 2018
    Assignee: AgaMatrix, Inc.
    Inventors: Ian Harding, Sridhar Iyengar, Richard Williams
  • Publication number: 20180088071
    Abstract: A test strip and analytical apparatus have pin connections permitting the definition of geographic regions or of particular customers. A test strip made for use in a particular region or for a particular customer will have pin connections matching features of the apparatus made for use in that region or by that customer. Insertion of the strip into the apparatus does not merely turn on the apparatus, but provides the regional or customer coding. Analog switches within the apparatus allow coding of a larger number of distinct regions or customers than would otherwise be possible, all without degrading the quality of the measurements made of the fluid being tested. Conductive paths in the strips permit testing the strips during manufacture so as to detect quality lapses regarding the printing or deposition of the paths.
    Type: Application
    Filed: December 4, 2017
    Publication date: March 29, 2018
    Applicant: AgaMatrix, Inc.
    Inventors: Steven Diamond, Martin Forest, Baoguo Wei, Ian Harding, Sridhar Iyengar
  • Publication number: 20180080895
    Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.
    Type: Application
    Filed: November 29, 2017
    Publication date: March 22, 2018
    Applicant: AgaMatrix, Inc.
    Inventors: Ian Harding, Richard Williams, Sridhar Iyengar
  • Patent number: 9907499
    Abstract: Correction for initial variation in thickness of a polymer layer and for changes in the coating thickness that occur after implantation of a biosensor and therefore provides substantial increase in the accuracy and lifetime of implantable sensors is done using a factor derived from the decay of potential.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: March 6, 2018
    Assignee: AgaMatrix, Inc.
    Inventors: Sridhar Iyengar, Ian Harding
  • Patent number: 9907501
    Abstract: Correction for initial variation in thickness of a polymer layer and for changes in the coating thickness that occur after implantation of a biosensor and therefore provides substantial increase in the accuracy and lifetime of implantable sensors is done using a factor derived from the decay of potential.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: March 6, 2018
    Assignee: AgaMatrix, Inc.
    Inventors: Sridhar Iyengar, Ian Harding
  • Publication number: 20180016624
    Abstract: Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include a preloaded reagent contained in each sample chamber and configured for nucleic acid analysis of a biological sample that enters the substrate and a sealing instrument configured to be placed in contact with the substrate to seal each sample chamber so as to substantially prevent sample contained in each sample chamber from flowing out of each sample chamber. The substrate can be constructed of detection-compatible and assay-compatible materials.
    Type: Application
    Filed: July 24, 2017
    Publication date: January 18, 2018
    Inventors: Min YUE, David M. LIU, Joy ROY, Yuh-Min CHIANG, Joon Mo YANG, Dennis LEHTO, Charles S. VANN, Nigel P. BEARD, Ian A. HARDING, John R. Van Camp, Alexander DROMARETSKY, Sergey V. ERMAKOV, Mark F. OLDHAM, Maryam SHARIATI, Umberto ULMANELLA
  • Patent number: 9857324
    Abstract: The presence of oxygen or red blood cells in a sample applied to an electrochemical test strip that makes use of a reduced mediator is corrected for by an additive correction factor that is determined as a function of the temperature of the sample and a measurement that reflects the oxygen carrying capacity of the sample. The measured oxygen carrying capacity can also be used to determine hematocrit and to distinguish between blood samples and control solutions applied to a test strip.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: January 2, 2018
    Assignee: AgaMatrix, Inc.
    Inventors: Ian Harding, Richard Williams, Sridhar Iyengar
  • Patent number: 9846140
    Abstract: A method is provided for determining analyte concentrations, for example glucose concentrations, that utilizes a dynamic determination of the appropriate time for making a glucose measurement, for example when a current versus time curve substantially conforms to a Cottrell decay, or when the current is established in a plateau region. Dynamic determination of the time to take the measurement allows each strip to operate in the shortest appropriate time frame, thereby avoiding using an average measurement time that may be longer than necessary for some strips and too short for others.
    Type: Grant
    Filed: January 5, 2016
    Date of Patent: December 19, 2017
    Assignee: AgaMatrix, Inc.
    Inventors: Steven Diamond, Ian Harding, Sridhar G. Iyengar, Baoguo Wei
  • Publication number: 20170350847
    Abstract: The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood.
    Type: Application
    Filed: June 15, 2017
    Publication date: December 7, 2017
    Applicant: AgaMatrix, Inc.
    Inventors: Ian Harding, Sridhar G. Iyengar, Baoguo Wei, Steven Diamond, Martin Forest
  • Patent number: 9835577
    Abstract: A test strip and analytical apparatus have pin connections permitting the definition of geographic regions or of particular customers. A test strip made for use in a particular region or for a particular customer will have pin connections matching features of the apparatus made for use in that region or by that customer. Insertion of the strip into the apparatus does not merely turn on the apparatus, but provides the regional or customer coding. Analog switches within the apparatus allow coding of a larger number of distinct regions or customers than would otherwise be possible, all without degrading the quality of the measurements made of the fluid being tested. Conductive paths in the strips permit testing the strips during manufacture so as to detect quality lapses regarding the printing or deposition of the paths.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: December 5, 2017
    Assignee: AgaMatrix, Inc.
    Inventors: Steven Diamond, Martin Forest, Baoguo Wei, Ian Harding, Sridhar Iyengar
  • Patent number: 9714444
    Abstract: Systems and methods for multiple analyte detection include a system for distribution of a biological sample that includes a substrate, wherein the substrate includes a plurality of sample chambers, a sample introduction channel for each sample chamber, and a venting channel for each sample chamber. The system may further include a preloaded reagent contained in each sample chamber and configured for nucleic acid analysis of a biological sample that enters the substrate and a sealing instrument configured to be placed in contact with the substrate to seal each sample chamber so as to substantially prevent sample contained in each sample chamber from flowing out of each sample chamber. The substrate can be constructed of detection-compatible and assay-compatible materials.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: July 25, 2017
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventors: Min Yue, David M. Liu, Joy Roy, Yuh-Min Chiang, Joon Mo Yang, Dennis Lehto, Charles S. Vann, Nigel P. Beard, Ian A. Harding, John R. Van Camp, Alexander Dromaretsky, Sergey V. Ermakov, Mark F. Oldham, Maryam Shariati, Umberto Ulmanella
  • Publication number: 20170205370
    Abstract: A test strip with an incorporated optical waveguide and deflectors punched through the optical waveguide allows light to exit through a layer of the test strip and be detected by a photo detector. Using light and a photodetector, these uniquely coded strips are identified. The waveguide can be constructed by sandwiching two layers of the test strip around a light transmissible layer. This configuration allows light to be transmitted through the test strip and out the other end, as well as allowing some light to escape the deflector. This light is detected by a photodetector mounted in the analyte test meter. The deflectors may be placed in patterns such that detection of this light indicates certain characteristics of the strip, such as non-counterfeit, regional identification, type of analyte tested, and coding information.
    Type: Application
    Filed: April 3, 2017
    Publication date: July 20, 2017
    Applicant: AgaMatrix, Inc.
    Inventors: Sridhar Iyengar, Ian Harding, Charles Boiteau, Colin Butters
  • Patent number: 9709519
    Abstract: The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: July 18, 2017
    Assignee: AgaMatrix, Inc.
    Inventors: Ian Harding, Sridhar G. Iyengar, Baoguo Wei, Steven Diamond, Martin Forest