Abstract: A projectile detection system, and method of detecting a projectile (for example a bullet), for use on a vehicle (100) (for example a helicopter), the projectile detection system comprising: a radar antenna array (4) arranged to transmit and receive microwave signals so as to provide a plurality of detection segments (40, 42, 44, 46) of a volume of airspace (38); one or more processors (3) arranged to: determine which segments (40, 42, 44, 46) microwave signals reflected by a projectile (10) are received from; determine timing information relating to a time order in which the received microwave signals are received; and determine directional information relating to a direction of travel of the projectile (10) using the determined segments (40, 42, 44, 46) and the determined timing information; wherein the microwave signals have a frequency between 1 GHz and 30 GHz.

Abstract: An antenna system, comprising: a phased array antenna (4); and a dielectric lens arrangement (6), for example a single solid dielectric lens (6) comprising a substantially spherical convex surface (12) and a concave surface (14); wherein the dielectric lens arrangement (6) is arranged to magnify the effective aperture of the phased array antenna (4). The concave surface (14) is positioned within the near field of the phased array antenna (4). The phased array antenna (4) is operated at a frequency greater than or equal to 50 GHz. The antenna system retains some ability to electronically scan the beam. The antenna system may be for transmission and/or reception. The antenna system may be used for example for communication between two vehicles.

Abstract: N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula (I): Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-? expression utilizing compounds of the present invention are also disclosed.

Abstract: Compounds of the formula are disclosed as Mnk2 inhibitors which are useful for the treatment and prevention of metabolic disorders such as obesity and diabetes.

Abstract: A frost protection system is described for a condensate drain pipe for a boiler, air-conditioning unit etc to protect an outdoors run of the pipe. The system comprises an outdoors temperature sensor, a heater, and a controller for activating the heater in dependence upon the temperature sensed by the sensor. The heater is in the form of a flexible line (for example an electrical cable with a resistive filament). The heater (or a connection for it) passes through a fitting in the pipe indoors, and the heater extends along the inside of the outdoors run of the pipe. In cold weather, the controller activates the heater to produce heat inside the drain pipe and thus reduce the risk of the condensate freezing.

Abstract: Compounds of the formula wherein R1 represents optionally substituted C1-C10 alkyl, aryl or heteroaryl, and R3 represents alkoxy-substituted aryl or optionally substituted heteroaryl, are disclosed as Mnk2 inhibitors which are useful for the treatment and prevention of metabolic disorders such as obesity and diabetes.

Abstract: The invention relates to 2-aminobenzimidazoles useful in treating disorders that are mediated by A2a receptor function, including neurodegenerative diseases including Parkinson's disease and inflammation.

Abstract: An antenna is provided, in combination with an associated switch array, the antenna comprising a number of antenna elements mounted above a ground plane for providing coverage over a predetermined range of angles in azimuth using a number of beams. Each of the antenna elements is connected to a switch in the switch array and the switch array is operable to connect selected pairs of the antenna elements to a signal path to thereby generate each of the different beams, at the same time connecting unselected antenna elements to ground.

Abstract: Phased array antennas, in particular highly coupled arrays of dipoles having a vertical electrical feed structure. A phased array antenna including a plurality of antenna elements and a plurality of electrical feed structures, wherein each feed structure serves an antenna element and each electrical feed structure is at least partially substantially surrounded by a ferrite element.

Abstract: Provided herein are Aminopurine Compounds having the following structure: wherein R1, R2 and and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

Abstract: The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.

Abstract: This invention relates to a radiating element 20 for use in array antennas. The radiating element 20 is of simplified design and comprises a front region 26 and a rearward region 28 that are preferably substantially rectangular, which permit higher frequency limits than more conventional Vivaldi elements while maintaining the lower frequency limit. Additionally, by deployment of an array of a plurality of such elements 20 such that no gaps are formed between adjacent elements 20 along the array antenna, very wide bandwidth can be obtained using the array.

Abstract: An antenna is provided, in combination with an associated switch array, the antenna comprising a number of antenna elements mounted above a ground plane for providing coverage over a predetermined range of angles in azimuth using a number of beams. Each of the antenna elements is connected to a switch in the switch array and the switch array is operable to connect selected pairs of the antenna elements to a signal path to thereby generate each of the different beams, at the same time connecting unselected antenna elements to ground.

Abstract: The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.

Abstract: Provided herein are Aminopurine Compounds having the following structure: wherein R1, R2 and and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

Abstract: This invention relates to a radiating element 20 for use in array antennas. The radiating element 20 is of simplified design and comprises a front region 26 and a rearward region 28 that are preferably substantially rectangular, which permit higher frequency limits than more conventional Vivaldi elements while maintaining the lower frequency limit. Additionally, by deployment of an array of a plurality of such elements 20 such that no gaps are formed between adjacent elements 20 along the array antenna, very wide bandwidth can be obtained using the array.

Abstract: The invention relates to purinone derivatives useful in treating disorders that are mediated by adenosine receptor function, including neurodegenerative diseases and inflammation.

Abstract: N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula I: Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-? expression utilizing compounds of the present invention are also disclosed.

Abstract: The invention relates to substituted 2-aminothiazole derivatives useful in treating disorders that are mediated by A2a receptor function, including neurodegenerative diseases including Parkinson's disease and inflammation.

Abstract: CXCR3 inhibitors of formula are disclosed. Inhibition of CXCR3 activation is useful for treating disorders resulting from CXCR3-associated T-cell mediated function, such as inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis and diabetes, as well as in the prevention of allograft rejection. N-ethyl-1,4-diazepane-1-carboxamides in which R1 is substituted or unsubstituted arylalkyl and R3 is substituted or unsubstituted aryl are particularly preferred.