Patents by Inventor Ian L. Scott

Ian L. Scott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Alkoxy compounds for disease treatment
    Patent number: 7982071
    Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: July 19, 2011
    Assignee: Acucela Inc.
    Inventors: Ian L. Scott, Vladimir A. Kuksa, Mark W. Orme, Thomas Little, Anna Gall, Feng Hong
  • Pharmacology of Visual Cycle Modulators
    Publication number: 20110003895
    Abstract: Described herein are methods for the treatment of an ophthalmic disease or disorder comprising the administration of non-retinoid visual cycle modulators.
    Type: Application
    Filed: July 2, 2010
    Publication date: January 6, 2011
    Applicant: ACUCELA, INC.
    Inventors: Ryo Kubota, Nancy Boman, Claes Bavik, Ian L. Scott
  • Vinorelbine derivatives
    Patent number: 7842802
    Abstract: The present invention relates to novel vinorelbine derivatives. Pharmaceutical compositions containing these compounds as well as processes of preparation and processes of use for treatment of various conditions are also disclosed.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: November 30, 2010
    Assignee: Albany Molecular Research, Inc.
    Inventors: Ian L. Scott, Jeffrey M. Ralph, Matthew E. Voss
  • Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
    Patent number: 7812038
    Abstract: A method for the inhibition of the binding of ?4?1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which ?4?1 is involved.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: October 12, 2010
    Assignee: Encysive Pharmaceuticals, Inc.
    Inventors: Ronald J. Biediger, Qi Chen, E. Radford Decker, George W. Holland, Jamal M. Kassir, Wen Li, Robert V. Market, Ian L. Scott, Chengde Wu, Jian Li
  • Vinca derivatives
    Patent number: 7745619
    Abstract: The present invention relates to derivatives of vinca alkaloids. Pharmaceutical compositions containing these compounds as well as processes of preparation and treatment of various conditions are also disclosed.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: June 29, 2010
    Assignee: Albany Molecular Research, Inc.
    Inventors: Ian L. Scott, Jeffrey M. Ralph, Matthew E. Voss
  • COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
    Publication number: 20100113539
    Abstract: Provided are compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.
    Type: Application
    Filed: October 21, 2009
    Publication date: May 6, 2010
    Applicant: Acucela, Inc.
    Inventors: Ian L. Scott, Vladimir Aleksandrovich Kuksa, Feng Hong, Ryo Kubota, Jennifer Gage
  • SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
    Publication number: 20100093865
    Abstract: Provided are sulphur-linked compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.
    Type: Application
    Filed: September 2, 2009
    Publication date: April 15, 2010
    Applicant: Acucela, Inc.
    Inventors: Ian L. Scott, Vladimir A. Kuksa, Ryo Kubota
  • Alkoxy compounds for disease treatment
    Publication number: 20090326074
    Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.
    Type: Application
    Filed: October 3, 2008
    Publication date: December 31, 2009
    Applicant: Acucela Inc.
    Inventors: Ian L. Scott, Vladimir A. Kuksa, Mark W. Orme, Thomas Little, Anna Gall, Feng Hong
  • Diaryl substituted pyridinones
    Patent number: 7629363
    Abstract: Disclosed are compounds Formula I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3/R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: December 8, 2009
    Assignee: Pfizer Inc
    Inventors: Balekudru Devadas, John Walker, Shaun R. Selness, Terri L. Boehm, Richard C. Durley, Rajesh Devraj, Brian S. Hickory, Paul V. Rucker, Kevin D. Jerome, Heather M. Madsen, Edgardo Alvira, Michele A. Promo, Radhika M. Blevis-Bal, Laura D. Marruto, Jeff Hitchcock, Thomas Owen, Win Naing, Li Xing, Huey S. Shieh, Aruna Sambandam, Shuang Liu, Ian L. Scott, Kevin F. McGee
  • Amine Derivative Compounds for Treating Ophthalmic Diseases and Disorders
    Publication number: 20090281149
    Abstract: Provided are amine derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.
    Type: Application
    Filed: October 22, 2008
    Publication date: November 12, 2009
    Applicant: Acucela, Inc.
    Inventors: Ian L. Scott, Vladimir A. Kuksa, Mark W. Orme, Feng Hong, Thomas L. Little, JR., Ryo Kubota
  • COMPOSITIONS AND METHODS FOR TREATMENT OF OPHTHALMIC DISEASES AND DISORDERS
    Publication number: 20090197967
    Abstract: Provided herein are compositions and methods for treating ophthalmic diseases and disorders. Compositions comprising retinylamine derivative compounds provided herein are useful for treating and preventing ophthalmic diseases and disorders, including diabetic retinopathy diabetic maculopathy, diabetic macular edema, retinal ischemia, ischemia-reperfusion related retinal injury, and metabolic optic neuropathy.
    Type: Application
    Filed: January 26, 2007
    Publication date: August 6, 2009
    Inventors: Ryo Kubota, Ahmad Fawzi, Ian L. Scott, Vladimir A. Kuksa
  • VINORELBINE DERIVATIVES
    Publication number: 20090088568
    Abstract: The present invention relates to novel vinorelbine derivatives. Pharmaceutical compositions containing these compounds as well as processes of preparation and processes of use for treatment of various conditions are also disclosed.
    Type: Application
    Filed: December 10, 2008
    Publication date: April 2, 2009
    Applicant: AMR TECHNOLOGY, INC.
    Inventors: Ian L. Scott, Jeffrey M. Ralph, Matthew E. Voss
  • VINORELBINE DERIVATIVES
    Publication number: 20080125451
    Abstract: The present invention relates to novel vinorelbine derivatives. Pharmaceutical compositions containing these compounds as well as processes of preparation and processes of use for treatment of various conditions are also disclosed.
    Type: Application
    Filed: September 12, 2007
    Publication date: May 29, 2008
    Applicant: AMR TECHNOLOGY, INC.
    Inventors: Mark A. WOLF, Peter R. GUZZO, Ian L. SCOTT
  • VINCA DERIVATIVES
    Publication number: 20080119502
    Abstract: The present invention relates to derivatives of vinca alkaloids. Pharmaceutical compositions containing these compounds as well as processes of preparation and treatment of various conditions are also disclosed.
    Type: Application
    Filed: September 12, 2007
    Publication date: May 22, 2008
    Applicant: AMR TECHNOLOGY, INC.
    Inventors: Mark A. WOLF, Peter R. GUZZO, Ian L. SCOTT
  • Vinca derivatives
    Patent number: 7238704
    Abstract: The present invention relates to derivatives of vinca alkaloids. Pharmaceutical compositions containing these compounds as well as processes of preparation and treatment of various conditions are also disclosed.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: July 3, 2007
    Assignee: AMR Technology, Inc.
    Inventors: Ian L. Scott, Jeffrey M. Ralph, Matthew E. Voss
  • Vinorelbine derivatives
    Patent number: 7235564
    Abstract: The present invention relates to novel vinorelbine derivatives. Pharmaceutical compositions containing these compounds as well as processes of preparation and processes of use for treatment of various conditions are also disclosed.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: June 26, 2007
    Assignee: AMR Technology, Inc.
    Inventors: Ian L. Scott, Jeffrey M. Ralph, Matthew E. Voss
  • Substituted pyridinones
    Patent number: 7067540
    Abstract: Disclosed are compounds Formula I and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: June 27, 2006
    Assignee: Pharmacia Corporation
    Inventors: Balekudru Devadas, John Walker, Shaun R. Selness, Terri L. Boehm, Richard C. Durley, Rajesh Devraj, Brian S. Hickory, Paul V. Rucker, Kevin D. Jerome, Heather M. Madsen, Edgardo Alvira, Michele A. Promo, Radhika M. Blevis-Bal, Laura D. Marruto, Jeff Hitchcock, Thomas Owen, Win Naing, Li Xing, Huey S. Shieh, Aruna Sambandam, Shuang Liu, Ian L. Scott, Kevin F. McGee
  • Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
    Patent number: 6972296
    Abstract: A method for the inhibition of the binding of ?4?1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which ?4?1 is involved.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: December 6, 2005
    Assignee: Encysive Pharmaceuticals Inc.
    Inventors: Ronald J. Biediger, Qi Chen, E. Radford Decker, George W. Holland, Jamal M. Kassir, Wen Li, Robert V. Market, Ian L. Scott, Chengde Wu, Jian Li
  • Propanoic acid derivatives that inhibit the binding of integrins to their receptors
    Patent number: 6723711
    Abstract: A compound of the structure A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1(vascular cell adhesion molecule-1) and fibronectin; pharmaceutically active compositions comprising these compounds; and the use of these compounds for the control or prevention of diseases states in which &agr;4&bgr;1 is involved are also disclosed.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: April 20, 2004
    Assignee: Texas Biotechnology Corporation
    Inventors: Ronald J. Biediger, Brian Dupre, Linda K. Hamaker, George W. Holland, Jamal M. Kassir, Wen Li, Robert V. Market, Noel Nguyen, Ian L. Scott, Chengde Wu, E. Radford Decker
  • Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
    Publication number: 20040063955
    Abstract: A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which &agr;4&bgr;1 is involved.
    Type: Application
    Filed: October 9, 2001
    Publication date: April 1, 2004
    Inventors: Ronald J. Biediger, Qi Chen, E. Radford Decker, George W. Holland, Jamal M. Kassir, Wen Li, Robert V. Market, Ian L. Scott, Chengde Wu, Jian Li