Abstract: An external rearview device for a vehicle includes a rearview element comprising at least one of a reflective element, a camera, or a display element; a housing configured to be attached to the vehicle and configured to be moveable relative to the vehicle; and a bezel affixed to an opening defined by the housing and surrounding the rearview element. The bezel is coated and a coating of the bezel is at least one of a decorative coating, an advanced surface technology, or a spectrally controlling system, and the rearview element is coupled to at least one of the bezel or the housing.

Abstract: A lottery ticket dispensing unit includes at least one ticket compartment and a separation module that has a drive roller and an opposed idler roller, with a motor geared to the drive roller. An automatic separator device is provided, wherein the drive roller conveys a leading lottery ticket to a separation position such that a line between the leading ticket and an adjacent ticket is presented to the separator device. The separator device includes a shuttle that travels in a linear path along the line, the shuttle having a head that engages and separates the leading ticket from the adjacent ticket along the line. A bi-directional drive mechanism moves the shuttle back and forth along the linear path.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: The invention relates to an optical fiber connector and to a related method for changing the polarity thereof. The connector comprises a ferrule, housing a plurality of terminations of optical fibers, and an inner housing arranged around the ferrule and comprising a rear portion and a front portion configured to be inserted into an optical fiber adapter.

Abstract: A failure of a head is detected, the head reading from and writing to an affected surface of a disk of a disk drive. The failure prevents the head from writing to the affected surface but does not prevent the head from reading from the affected surface. In response to detecting the failure, a remediation is performed. The remediation involves determining spare capacity blocks on other surfaces of the disk drive different than the affected surface, and copying data from the affected surface to the spare capacity blocks via an internal copy function within the disk drive. The spare capacity blocks in place of the affected surface for data storage and retrieval subsequent to the failure.

Abstract: The present invention relates to a compound of the Formula: and pharmaceutically salts thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: Described herein are methods and devices for improved location of any and all underwater structures or equipment installed underwater. In particular, systems are disclosed that combine optical and acoustic metrology for locating objects in underwater environments. The systems allow for relative positions of objects to be determined with great accuracy using optical techniques, and support enhanced location of devices that utilize acoustic location techniques. In addition, location information can be provided by the system even in conditions that make optical metrology techniques impossible or impractical.

Abstract: The disclosed embodiments relate to a system and method which utilizes the benefits of both advertising and bidirectional connections to allow a client/receiving device to receive data, e.g. sensor measurements, from the source/transmitting device during device discovery and connection, thereby minimizing the amount of time during which data, e.g. measurements, are unavailable. The disclosed embodiments may further allow for reduced power consumption by a source device by minimizing data transmission during advertising.

Abstract: Systems, methods, and computer-program products for entity resolution are disclosed. Entity resolution embodiments include receiving tree data from each of a pair of entities, extracting and/or aggregating feature vectors or metric functions therefrom, and generating similarity scores between the pair of entities. The similarity scores may be weighted using machine-learned weights. The weighted similarity scores are used to generate a combinatorial probability score accounting for combined likelihoods of field values between the pair of entities. A classification of the pair of entities is performed based on the combinatorial probability score, with a genealogical database modified based on the classification.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: This invention concerns a laser solidification apparatus for building objects by layerwise solidification of powder material. The apparatus including a build chamber containing a build platform, a device for depositing layers of powder material on to the build platform, an optical unit for directing a laser beam to selectively solidify areas of each powder layer and a spectrometer for detecting characteristic radiation emitted by plasma formed during solidification of the powder by the laser beam. The invention also relates to a spectrometer for detecting characteristic radiation generated by interaction of the metal with the or a further laser beam. The spectra recorded using the spectrometer may be used for feedback control during the solidification process.

Abstract: A carton including: a) a base; b) a lid having a top side and underside; c) a first side; d) a front side, wherein at least a portion of the front side is located adjacent to the first side and there is an arcuate transition between the first side and the front side; e) a second side, wherein at least a portion of the second side is located adjacent to the front side and there is an arcuate transition between the second side and the front side; and f) a back side, wherein a portion of the back side is located adjacent to the first side and a portion of the back side is located adjacent to the second side and the back side has no arcuate transitions between itself, the first side, or the second side.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: Provided herein are IL-2 muteins, IL-2 mutein Fc-fusion molecules, anti-IL-2 antibodies, and complexes comprising an anti IL-2 antibody bound to an IL-2 cytokine that preferentially expand and activate T regulatory cells and are amenable to large scale production. Also provided herein are variant human IgG1 Fc molecules lacking or with highly reduced effector function and high stability despite lacking glycosylation at N297. Also provided herein are linker peptides that are glycosylated when expressed in mammalian cells. Also provided herein are methods of making and using the compositions of the present invention.

Abstract: An aircraft landing gear shock absorber strut including an outer cylinder having a bore defining an opening; an inner cylinder having a first end region movably coupled within the bore and a second end region which projects out of the opening. The inner cylinder being arranged to move along a longitudinal axis of the bore between a first condition and a second condition and is biased by a spring force to assume the second condition. A mechanical outstop is arranged to engage an abutment surface of the inner cylinder to limit extension of the shock absorber strut; and a rotatable member drives the out stop axially to move the inner cylinder from the second condition towards the first condition. The rotatable member is arranged such that the spring force cannot rotate the rotatable member to allow the shock absorber strut to extend.

Abstract: The present invention relates to a compound of the Formula: or a pharmaceutically acceptable salt thereof. The compound of the present invention inhibits Pol?. This novel therapeutic compound is therefore useful for the treatment and/or prevention of diseases and conditions in which Pol? activity is implicated, such as, for example but not limited to, the treatment and/or prevention of cancer. The present invention also relates to pharmaceutical compositions comprising the novel therapeutic compound defined herein, to processes for synthesising the compound and to their use for the treatment of diseases and/or conditions in which Pol? activity is implicated.

Abstract: Perception sensors of a vehicle can be used for various operating functions of the vehicle. A computing device may receive sensor data from the perception sensors, and may calibrate the perception sensors using the sensor data, to enable effective operation of the vehicle. To calibrate the sensors, the computing device may project the sensor data into a voxel space, and determine a voxel score comprising an occupancy score and a residual value for each voxel. The computing device may then adjust an estimated position and/or orientation of the sensors, and associated sensor data, from at least one perception sensor to minimize the voxel score. The computing device may calibrate the sensor using the adjustments corresponding to the minimized voxel score. Additionally, the computing device may be configured to calculate an error in a position associated with the vehicle by calibrating data corresponding to a same point captured at different times.

Abstract: Systems and methods for yield prediction for a field using spatial data representing yield throughout the field and multiple measurements of actual yield obtained from field regions during harvesting of the field. A yield model is generated based on the spatial data and the multiple measurements of actual yield. The yield model is used to determine information related to yield in the field.

Abstract: An internal multi-function rearview device for use with a vehicle includes a rearview element comprising at least one of a reflective element, a camera, or a display element; a housing configured to be attached to the vehicle and configured to be moveable relative to the vehicle; a bezel configured to be affixed to an opening defined by the housing and configured to surround the rearview element; and a foot configured to be fixed to the vehicle and relative to which the housing and bezel is moveable. The bezel is coated and a coating of the bezel is at least one of a decorative coating, an advanced surface technology, or a spectrally controlling system, and the rearview element is coupled to at least one of the bezel or the housing.