Abstract: An aircraft landing gear comprising: an arm mounted to a pivot and carrying one or more wheel assemblies; and a composite leaf spring which is coupled to the arm and arranged to provide a resilient biasing force which opposes rotation of the arm about the pivot. The arm can be made relatively stiff in comparison with the leaf spring, so that load is transferred directly into the pivot without a large amount of bending of the leg. The leaf spring shock absorber typically has a reduced part count compared with a conventional oleo-pneumatic shock absorber. By forming the leaf spring from a composite material, its weight is significantly reduced in comparison with a conventional metal spring, making it suitable for use on a relatively large aircraft.

Abstract: An administering device for administering an active substance from a multi-chamber container comprising a first chamber holding a solid active substance and a second chamber holding a dissolving liquid for the active substance, wherein the administering device comprises a mixing device for mixing the active substance with the dissolving liquid and a housing accommodating the mixing device, the container being moveable relative to the housing, and the administering device further comprising a first indicator for indicating a position of the container relative to the housing upon completion of a mixing step, and a second indicator for indicating a position of the container relative to the housing upon completion of a venting step.

Abstract: The invention relates to point of care diagnostic disposables, devices, methods, and systems for diagnosing or predicting prostate cancer. The present invention employs biomarker specific reagents in disposable cassettes or lab cards for use as analyzers, as well as software to evaluate and report test results. The system promises to improve point of care in vitro diagnostics.

Abstract: An administering device for administering an active substance from a multi-chamber container comprising a first chamber holding a solid active substance and a second chamber holding a dissolving liquid for the active substance, wherein the administering device comprises a mixing device for mixing the active substance with the dissolving liquid and a housing accommodating the mixing device, the container being moveable relative to the housing, and the administering device further comprising a first indicator for indicating a position of the container relative to the housing upon completion of a mixing step, and a second indicator for indicating a position of the container relative to the housing upon completion of a venting step.

Abstract: A method of braked pivot turning an aircraft, the aircraft comprising a fuselage and a landing gear assembly located to one side thereof. The landing gear comprises a bogie with wheels mounted thereon, at least one wheel being located on a first side of the bogie and at least one wheel being located on a second side of the bogie. The method includes the steps of applying thrust (7?) for moving or turning the aircraft, and via the braking of at least one wheel, applying a greater braking force to the first side of the bogie than to the second side. The first side is located closer to the center of turning of the aircraft than the second side. The method thereby generates relatively low torque loads in the landing gear leg, reducing fatigue damage. A brake control system is also provided for selectively braking wheels during a turn.

Abstract: A system is provided for mounting a mixing valve on a support surface to connect the mixing valve (101) to supply pipes (109, 111) projecting from the support surface. The system includes a mounting plate (103) for securing to the support surface so that the supply pipes (109, 111) pass through openings in the mounting plate (103). Sleeves (159, 161) fit over the projecting ends of the supply pipes (109, 111) for reception in inlets of the mixing valve (101) to thereby compress the sleeves (159, 161) to grip and retain the pipes (109, 111) in the inlets. The mixing valve (101) is releasably secured to the mounting plate (103) allowing the mixing valve (101) to be detached and the sleeves (159, 161) and mounting plate (103) to be removed from the pipes (109, 111).

Abstract: An apparatus and method for detecting infected tissue are disclosed. The apparatus comprises a light source for producing a light beam and an optical element having an input end optically coupled to the light source and an output end arranged to direct the light beam as a confocal beam into tissue. The apparatus also comprise a detector optically coupled to the optical element to receive a return beam back from the tissue stimulated by the confocal beam and to generate an output dependent upon the return beam.

Abstract: A multi-lamellar tissue-adhesive sheet comprises a structural layer or laminate conjoined to a tissue-contacting layer. The structural layer or laminate comprises one or more synthetic polymers having film-forming properties, and the tissue-contacting layer of material contains tissue-reactive groups. The synthetic polymers having film-forming properties are preferably biodegradable polyesters, and the tissue-reactive groups are most preferably NHS-ester groups.

Abstract: This invention related to a tissue-adhesive sheet comprising a homogeneous, preformed and cross-linked matrix formed from one or more polymers, and having at least one surface that, in use, is exposed, at least one of said one or more polymers being a synthetic polymer and having appendant functional groups of a first form, cross-linking of said matrix being via a proportion of said functional groups of the first form, and the remainder of said functional groups of the first form being free. The sheet is particularly useful as a tissue adhesive and sealant, and is intended for topical application to internal and external surfaces of the body for therapeutic reasons. The invention further relates to sheets comprising a scaffold material, three-dimensional articles formed from similar material to that of the sheet and to implantable medical devices coated with such material.

Abstract: A method of removing an adhesive resin from a dental tooth which method comprises contacting the dental tooth with a bioactive glass using an air abrasion system.

Abstract: An aircraft landing gear comprising: an arm mounted to a pivot and carrying one or more wheel assemblies; and a composite leaf spring which is coupled to the arm and arranged to provide a resilient biasing force which opposes rotation of the arm about the pivot. The arm can be made relatively stiff in comparison with the leaf spring, so that load is transferred directly into the pivot without a large amount of bending of the leg. The leaf spring shock absorber typically has a reduced part count compared with a conventional oleo-pneumatic shock absorber. By forming the leaf spring from a composite material, its weight is significantly reduced in comparison with a conventional metal spring, making it suitable for use on a relatively large aircraft.

Abstract: An implantable medical device carries on at least part of its external surface a coating. The coating consists essentially of a terpolymer of vinyl pyrrolidone, acrylic acid and activated acrylic acid, and optionally a colouring agent.

Abstract: An injection device for use with a two-chamber ampoule, wherein the device includes a front casing part with which the two-chamber ampoule can be associated, a rear casing part, a threaded drive accommodated by the rear casing part, a piston rod which, during a blending movement, is moved by the threaded drive toward a dispensing end of the device and slaves at least a closing piston of the two-chamber ampoule in the process, wherein a spring element presses the piston rod toward the dispensing end during a delivery movement.

Abstract: This invention involves compositions and methods for protecting animals from pestivirus infection and for treating animals infected with pestivirus. Pharmaceutical compositions containing E2 and NS3 from a pestivirus are used to protect animals or treat animals.

Abstract: An injection device including a housing, a needle guard sleeve displaceable relative to the housing, and a spring coupled to the guard sleeve such that the guard sleeve can be moved by the spring distally from a proximal position to an end position, the spring also being coupled to a forward drive element displaceable relative to the housing in a drive direction wherein the spring is tensioned upon a movement of the forward drive element in the forward drive direction.

Abstract: The present invention provides a composite material comprising lactoferrin and a bioactive glass. The invention also relates to pharmaceutical compositions containing the composite material. Further aspects of the invention relate to the use of the composite material of the for treating a wound, treating or preventing bacterial or viral infections in a wound, preventing viral transmission, regenerating bone, treating osteoporosis, preventing or alleviating bleeding in a wound, sterilising a wound and/or controlling haemorrhaging.

Abstract: The present invention provides a composite material comprising fibrinogen or fibrin, or a mixture thereof, and a bioactive glass. The invention also relates to wound dressings and pharmaceutical compositions containing the composite material. Further aspects of the invention relate to the use of the composite material of the for treating a wound, treating or preventing bacterial infections in a wound, preventing or alleviating bleeding in a wound, sterilising a wound, controlling haemorrhaging, increasing the rate of coagulation of blood and/or activating a coagulation system in a wound.

Abstract: A tissue-adhesive formulation consists of a naturally occurring or synthetic polymerisable and/or cross-linkable material in particulate form, the polymerisable and/or cross-linkable material being in admixture with particulate material comprising tissue-reactive functional groups. The formulation may be used in the preparation of a tissue-adhesive sheet, by applying the formulation to at least one side of a core of a naturally occurring or synthetic polymeric material.

Abstract: An administering device for administering an active substance from a multi-chamber container comprising a first chamber holding a solid active substance and a second chamber holding a dissolving liquid for the active substance, wherein the administering device comprises a mixing device for mixing the active substance with the dissolving liquid and a housing accommodating the mixing device, the container being moveable relative to the housing, and the administering device further comprising a first indicator for indicating a position of the container relative to the housing upon completion of a mixing step, and a second indicator for indicating a position of the container relative to the housing upon completion of a venting step.

Abstract: An apparatus and method for detecting infected tissue are disclosed. The apparatus comprises a light source for producing a light beam and an optical element having an input end optically coupled to the light source and an output end arranged to direct the light beam as a confocal beam into tissue. The apparatus also comprise a detector optically coupled to the optical element to receive a return beam back from the tissue stimulated by the confocal beam and to generate an output dependent upon the return beam. An analyser is arranged to analyse the output of the detector to determine whether the return beam is indicative of infected tissue. The use of a confocal beam allows it to be directed to a specific predetermined point or depth in tissue, such as a tooth, thus eliminating the ‘swamping effect’ of the bulk background tissue. Thus an embodiment of the apparatus is more sensitive at detecting infected tissue.