Abstract: A material is excited with light whose intensity is modulated according to a modulation signal. The modulation signal includes multiple transitions between at least two intensity levels, with times of at least a first contiguous sequence of the transitions being selected according to an irregular pattern. A response of the material to the excitation is detected.

Abstract: Electrochemical redox supercapacitor. The supercapacitor includes two thin films of electrically conducting polymer separated by an ion-permeable membrane and including an electrolyte disposed between the two thin films. Electrical contacts are disposed on outer surfaces of the two thin films. The supercapacitor is flexible and may be rolled, folded on itself, or kept substantially flat. A suitable conducting polymer is polypyrrole. In another aspect, the invention is a method for making a redox supercapacitor.

Abstract: A method and apparatus for detecting and removing air from a syringe containing a volume of liquid and a volume of gas is described. The method includes moving a piston in the syringe to expel gas through an orifice of the syringe, sensing a movement of the piston in the syringe, and determining when the volume of gas is expelled from the syringe based on a change in the sensed movement. Moving the piston may include applying oscillating force to the piston using an electromagnetic actuator, and displacement and speed of the piston during each oscillation may be sensed. Determining when the volume of gas is expelled may be based on a change in the sensed movement of the piston during one or more oscillations of the piston or based on a comparison to a given reference value.

Abstract: A method and system for continuous measurement chromatograph involves stochastically modulating a system variable. The sample can be introduced into a chromatography column. The sample introduction can be modulated stochastically. The sample output from the column can be detected and processed with the stochastic input to provide a sample analysis.

Abstract: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.

Abstract: A device for measuring a mechanical property of a tissue includes a probe configured to perturb the tissue with movement relative to a surface of the tissue, an actuator coupled to the probe to move the probe, a detector configured to measure a response of the tissue to the perturbation, and a controller coupled to the actuator and the detector. The controller drives the actuator using a stochastic sequence and determines the mechanical property of the tissue using the measured response received from the detector. The probe can be coupled to the tissue surface. The device can include a reference surface configured to contact the tissue surface. The probe may include a set of interchangeable heads, the set including a head for lateral movement of the probe and a head for perpendicular movement of the probe. The perturbation can include extension of the tissue with the probe or sliding the probe across the tissue surface and may also include indentation of the tissue with the probe.

Abstract: The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber of a plurality of chambers. A plurality of electromagnetic actuators are in communication with the plurality of chambers. The actuators, when activated, generate a pressure within at least the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.

Abstract: The present invention relates to an endoscope having a motorized assembly to control the distal end of an endoscope. Preferred embodiments can include disposable and reusable components. The system reduces the force need to control the tip of the endoscope and thereby reduce the risk of perforation?.

Abstract: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.

Abstract: A miniature, low cost mass spectrometer capable of unit resolution over a mass range of 10 to 50 AMU. The mass spectrometer incorporates several features that enhance the performance of the design over comparable instruments. An efficient ion source enables relatively low power consumption without sacrificing measurement resolution. Variable geometry mechanical filters allow for variable resolution. An onboard ion pump removes the need for an external pumping source. A magnet and magnetic yoke produce magnetic field regions with different flux densities to run the ion pump and a magnetic sector mass analyzer. An onboard digital controller and power conversion circuit inside the vacuum chamber allows a large degree of flexibility over the operation of the mass spectrometer while eliminating the need for high-voltage electrical feedthroughs. The miniature mass spectrometer senses fractions of a percentage of inlet gas and returns mass spectra data to a computer.

Abstract: An electromagnetic actuator including: a core comprising a material having a high magnetic permeability relative to air; an array of coils sequentially arranged on the core, each coil of the array of coils being wound around the longitudinal axis of the core; and a magnet assembly movably mounted along the array of coils, the magnet assembly having a coil side facing the array of coils and an opposite side facing away from the array of coils and including an array of permanent magnets sequentially arranged along the array of coils in a direction parallel to the longitudinal axis, wherein the magnetic moments of the plurality of magnets are selected and arranged to augment the magnetic field produced on the coil side of the magnet assembly and to reduce the magnetic field produced on the opposite side of the magnet assembly.

Abstract: A rotary drive includes: a support structure; and a linear actuator supported by the support structure. The linear actuator includes: a first member; a second member that moves in a linear direction relative to the first member when a drive signal is applied to the linear actuator; and a bearing arrangement supporting the first and second members within the support structure and enabling independent movement of the first member and the second member relative to the support structure. The rotary drive also includes a linear-to-rotary converter to which the second member of the linear actuator is coupled. The linear-to-rotary converter includes an output member having a rotational axis. During operation, the linear-to-rotary converter converts linear reciprocating movement of the second member of the linear actuator to rotary movement of the output member about the rotational axis.

Abstract: A method for injecting a substance through a biological body surface includes providing a needle-free transdermal transport device configured to inject the substance through the surface. The substance is injected into the biological body with the transport device while a parameter of the injection is sensed and a servo-controller is used to dynamically adjust at least one injection characteristic based on the sensed parameter. The substance is injected for (i) a first time period during which a first portion of a volume of the substance is injected at a first injection pressure, and (ii) a second time period during which a remainder of the volume of the substance is injected at a second injection pressure. A viscosity of the substance may be determined, and a pressure calculated for injecting the substance based on the viscosity. The substance may be injected with the transport device by using the calculated pressure.

Abstract: A method for transferring a solid body across a surface of a biological body includes (i) applying an electrical input to a controllable electromagnetic actuator; (ii) producing with the electromagnetic actuator a mechanical force corresponding to the electrical input; and (iii) applying the mechanical force to a reservoir coupled at one end to a nozzle, the mechanical force producing a pressure within the reservoir, a magnitude of the pressure varying with the mechanical force and causing ejection of a fluid from the reservoir to drive the solid body into the biological body. A method for delivering a substance to a target body includes (i) positioning a needle-free injector proximate to a surface of the target body; (ii) injecting the substance into the target body; and (iii) while injecting, moving the needle-free injector along the surface, thereby sweeping the surface.

Abstract: A method of detecting whether a receiver coil is near a transmit coil in a wireless power transfer system (WPTS), the method involving: applying a pseudo-random signal to the transmit coil; while the pseudo-random signal is being applied to the transmit coil, recording one or more signals produced within the WPTS in response to the applied pseudo-random signal; by using the one or more recorded signals, generating a dynamic system model for some aspect of the WPTS; and using the generated dynamic system model in combination with stored training data to determine whether an object having characteristics distinguishing the object as a receiver coil is near the transmit coil.

Abstract: A method of detecting whether a receiver coil is near a transmit coil in a wireless power transfer system (WPTS), the method involving: applying a pseudo-random signal to the transmit coil; while the pseudo-random signal is being applied to the transmit coil, recording one or more signals produced within the WPTS in response to the applied pseudo-random signal; by using the one or more recorded signals, generating a dynamic system model for some aspect of the WPTS; and using the generated dynamic system model in combination with stored training data to determine whether an object having characteristics distinguishing the object as a receiver coil is near the transmit coil.

Abstract: An electric device including: a stator assembly; and an actuator including a coil having an axis, wherein the stator assembly includes: a stator core arranged along a linear axis, the stator core made up of a plurality of magnets each characterized by a magnetic moment, the plurality of magnets arranged in a stack along the linear axis with the magnet moments of the plurality of magnets being co-linearly aligned parallel to the linear axis, wherein the plurality of magnets includes a first magnet and a second magnet positioned adjacent to each other in the stack separated by a gap and with their magnetic moments in opposition to each other, and wherein the actuator is arranged on the stator core with the coil of the actuator encircling the linear axis with the axis of the coil parallel to the linear axis.

Abstract: A device for measuring a mechanical property of a tissue includes a probe configured to perturb the tissue with movement relative to a surface of the tissue, an actuator coupled to the probe to move the probe, a detector configured to measure a response of the tissue to the perturbation, and a controller coupled to the actuator and the detector. The controller drives the actuator using a stochastic sequence and determines the mechanical property of the tissue using the measured response received from the detector. The probe can be coupled to the tissue surface. The device can include a reference surface configured to contact the tissue surface. The probe may include a set of interchangeable heads, the set including a head for lateral movement of the probe and a head for perpendicular movement of the probe. The perturbation can include extension of the tissue with the probe or sliding the probe across the tissue surface and may also include indentation of the tissue with the probe.

Abstract: A method of detecting whether a foreign object is near a transmit coil in a wireless power transfer system (WPTS), the method involving: applying a pseudo-random signal to the transmit coil; while the pseudo-random signal is being applied to the transmit coil, recording one or more signals produced within the WPTS in response to the applied pseudo-random signal; by using the one or more recorded signals, generating a dynamic system model for some aspect of the WPTS; and using the generated dynamic system model in combination with stored training data to determine whether an object having characteristics recognizable from the stored training data as characteristic of the foreign object is near the transmit coil.

Abstract: A method of detecting whether a receiver coil is near a transmit coil in a wireless power transfer system (WPTS), the method involving: applying a pseudo-random signal to the transmit coil; while the pseudo-random signal is being applied to the transmit coil, recording one or more signals produced within the WPTS in response to the applied pseudo-random signal; by using the one or more recorded signals, generating a dynamic system model for some aspect of the WPTS; and using the generated dynamic system model in combination with stored training data to determine whether an object having characteristics distinguishing the object as a receiver coil is near the transmit coil.