Abstract: A compact case includes a sealing member opening/closing an upper end of a contents storage part. The sealing member is coupled with screws to a contents storage part, such that an open upper end of the contents storage part can be sealed by the screw combination of the contents storage part and the sealing member when a lower case is rotated. As a result, it is possible not only to improve the internal airtightness of the contents storage portion but also to prevent leakage of contents during the decompression process.

Abstract: The present invention relates to a N2-(2-methoxyphenyl)pyrimidine derivative, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of cancer comprising the same as an active ingredient. The N2-(2-methoxyphenyl)pyrimidine derivative, the optical isomer thereof, or the pharmaceutically acceptable salt thereof of the present invention is very effective in suppressing anaplastic lymphoma kinase (ALK) activity and as a result it can improve the effectiveness of treatment on cancer cells having anaplastic lymphoma kinase (ALK) fusion proteins such as EML4-ALK and NPM-ALK, so that it can be effectively used as a pharmaceutical composition for preventing or treating cancer.

Abstract: Provided is a compound activating ROR? gene, particularly a JC1 compound containing CGP52608 thiazolidinedione as a lead substance, and a pharmaceutically acceptable salt thereof. The compound is a lipid accumulation inhibitor and applicable to the treatment of metabolic diseases or inflammatory diseases.

Abstract: A compact container using magnets, and has a middle case and an upper case that are rotatably coupled through screw coupling, thereby improving the air-tightness of the interior thereof. When the screw coupling between the upper case and the middle case is released, the upper case is fixed to the upper end of the middle case while forming with at least 90 degrees of angle to the middle case via the magnet such that the above configuration can reduce assembly time by avoiding the traditional hinge structure and improve productivity.

Abstract: The present invention relates to a novel use of a thiourea derivative and, more specifically, to a pharmaceutical composition for preventing or treating autoimmune diseases comprising a thiourea derivative as an active ingredient. The thiourea derivative according to the present invention can inhibit the transcription of inflammatory genes such as TNF-?, IL-1?, NOS2 and IL-6, and also can inhibit the activity or production of Th17 and increase the activity or production of a regulatory T cell (Treg). Thus, it is expected that the thiourea derivative may be usefully used in a pharmaceutical composition, a health food composition, etc. for the prevention, improvement or treatment of various autoimmune diseases including rheumatoid arthritis.

Abstract: The present invention relates to a pyrimidine-2,4-diamine derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition for prevention or treatment of cancer comprising the same as an effective ingredient. A compound according to the present invention has the good effect of inhibiting anaplastic lymphoma kinase (ALK) activity, whereby a therapeutic effect on cancer cells having an anaplastic lymphoma kinase (ALK) fusion protein such as EML4-ALK, NPM-ALK, etc. can be enhanced and it is expected that a recurrence of cancer will be effectively inhibited. As such, the compound can be effectively used in a pharmaceutical composition for prevention or treatment of cancer.

Abstract: A liquid contents discharge container includes an absorption member configured in a way that when a rotation body rotates, liquid contents are discharged in an extrusion manner while a piston is ascending, and are absorbed into an absorption member to be used, such that it is possible to provide the same usability as a solid lipstick product which is familiar with users and to improve wearability of liquid contents, and by equipping a nozzle which opens only when contents are discharged, to prevent air from flowing into the interior of the container body when not in use.

Abstract: The present invention relates to a N2-(2-methoxyphenyl)pyrimidine derivative, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of cancer comprising the same as an active ingredient. The N2-(2-methoxyphenyl)pyrimidine derivative, the optical isomer thereof, or the pharmaceutically acceptable salt thereof of the present invention is very effective in suppressing anaplastic lymphoma kinase (ALK) activity and as a result it can improve the effectiveness of treatment on cancer cells having anaplastic lymphoma kinase (ALK) fusion proteins such as EML4-ALK and NPM-ALK, so that it can be effectively used as a pharmaceutical composition for preventing or treating cancer.

Abstract: The present invention relates to a 4-(2-amino-tetrahydronaphthaleneyl)pyrimidine derivative, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of cancer comprising the same as an active ingredient. The 4-(2-amino-tetrahydronaphthaleneyl)pyrimidine derivative, the optical isomer thereof, or the pharmaceutically acceptable salt thereof of the present invention is very effective in suppressing anaplastic lymphoma kinase (ALK) activity and as a result it can improve the effectiveness of treatment on cancer cells having anaplastic lymphoma kinase (ALK) fusion proteins such as EML4-ALK and NPM-ALK, so that it can be effectively used as a pharmaceutical composition for preventing or treating cancer.

Abstract: A cosmetic powder container that, when softly pressurized, as rubbing upward a lower surface of a rubber container where contents are stored in a state of an upper case being opened, the rubber container is deformed and thereby contents are discharged in an extrusive manner, therefore making it possible to discharge contents as needed while checking the contents being discharged with user's eyes.

Abstract: A cosmetic container having an absorption member impregnated with liquid contents, is characterized in that the absorption member, made of a porous material and impregnated with liquid contents, is compressed when a piston ascends with the rotation of a rotation body, whereby the impregnated liquid contents are withdrawn to an upper portion thereof for being used, thereby providing the same usability as solid lip stick products which are familiar to users and improving spreading properties.