Abstract: The present invention relates to an electric oven capable of reducing contaminants, the electric oven comprising: an oven body having a cavity capable of accommodating food therein; and a convection assembly which is installed to protrude from one surface of the cavity and which can suck and remove contaminants generated when cooking the food and can heat the inside of the cavity.

Abstract: Provided is a compound represented by Formula 1 having an inhibitory activity on lysine-specific demethylase-1 (LSD1), an optical isomer, a solvate, a tautomer, or a pharmaceutically acceptable salt thereof, which is effective in preventing or treating a disease caused by abnormal activation of LSD1.

Abstract: A semiconductor substrate includes a main surface inclined by a first off-angle greater than 0° from a first direction parallel to a crystal plane, with respect to the crystal plane, in a first radial direction of the main surface, and a notch disposed toward the first direction, at an edge of the main surface in the first radial direction.

Abstract: The present invention relates to a pharmaceutical composition for preventing, treating or alleviating cancer, containing a PLK1 inhibitor as an active ingredient, and a compound according to the present invention selectively binds to PBD of PLK1, thereby having advantages of high selectivity and binding affinity for PLK1 and low toxicity. Therefore, a PLK inhibitor compound according to the present invention can be effectively used as an anticancer agent by inhibiting the growth of various cancer cells, and can be expected to exhibit synergistic effects with existing developed anticancer agents through co-administration, in addition to individual administration thereof.

Abstract: The present invention relates to a method of screening for a cancer therapeutic agent using Cyclin B1, Cyclin-dependent kinase 1 (CDK1), and retinoic acid receptor responder 1 (RARRES1), and a composition for diagnosing cancer or predicting a prognosis using the same. As a result of having conducted intensive studies to discover molecular mechanisms for diagnosing cancer and predicting a prognosis, the inventors of the present invention confirmed that in cancer-derived samples, according to the degree of mutual binding between RARRES1 and CDK1 or Cyclin B1, the mitosis of cancer cells was arrested, the formation of CDK1-Cyclin B1 complexes was suppressed, and the degradation of these proteins was promoted, and thus RARRES1 was a crucial factor in the diagnosis of cancer, prognosis prediction, and the treatment of cancer.

Abstract: Disclosed herein are a washing machine and a control method thereof. The control method effectively transmits high-concentration wash liquid to laundry, while minimizing the amount of water used, through washing using bubbles, and maximizes the increase in volume of the wash liquid rubbed on the inner circumferential surface of the drum using the generation of bubbles and the rotation of the drum to raise the water level of the wash liquid without additional water.

Abstract: A holder for a vehicle holds various portable devices, such as cell phones and IT goods, by being firmly fixed to a grille of an air blowing hole by enabling four fixing bars to mechanically rotate according to the forward and backward movement of a pressurizing member such that one ends of the four fixing bars gather together or are separated from each other. The holder includes a housing having a through hole formed in the center of a front plate and four fixing bars. Each fixing bar has one end which protrudes to the front surface of the housing through the through hole so that the four fixing bars are inserted into a blowing hole and are supported on an air blowing hole grille, and another end having an arm that outwardly curves so that one side thereof is rotatably coupled to the inside of the front plate.

Abstract: A composition for an organic optoelectronic device, an organic optoelectronic device including the same, and a display device, the composition including a first compound represented by Chemical Formula 1, and a second compound represented by a combination of Chemical Formula 2 and Chemical Formula 3:

Abstract: According to an embodiment of the present invention, the bat exhibition and viewing system for providing habitat-based bat ecological viewing contents includes: a bat detector including an ultrasonic communication module for detecting an ultrasonic signal of a bat and radiating the ultrasonic signal generated therein to the outside, a signal conversion module for converting the ultrasonic signal of the bat into a social call of an audible band, and an interface module communicating with an external information communication terminal to transmit data received from the signal conversion module; and a viewing contents providing unit installed in the information communication terminal, audibly outputting sound of the bat in accordance with the social call, and extracting intention information matching the social call from pre-learned bat species-specific intention information to visually display the intention information.

Abstract: Provided is a polarizing plate for a light-emitting diode and a light-emitting display device including the same, the polarizing plate comprising a polarizing film and a liquid crystal retardation film, wherein the liquid crystal retardation film comprises a laminate made of: a second retardation film having a discotic liquid crystal of which an in-plane retardation Re, in a wavelength of 550 nm, is approximately 220 nm to approximately 280 nm and a biaxial degree (NZ) is approximately 0 to approximately 0.3; and a first retardation film having a nematic liquid crystal of which an in-plane retardation Re, in a wavelength of 550 nm, is approximately 100 nm to approximately 150 nm and a biaxial degree (NZ) is approximately 0.3 to approximately 0.7.

Abstract: The present invention relates to a cosmetic composition for whitening comprising a Caragana sinica root extract, and more specifically relates to a cosmetic composition having an outstanding skin-whitening effect, the composition comprising a Caragana sinica root extract, a fraction thereof or ?-viniferin isolated therefrom. In the present invention, the Caragana sinica root extract, fraction thereof or ?-viniferin isolated therefrom inhibits tyrosinase activity and suppresses melanin production and is therefore effective in skin whitening.

Abstract: The extract of a mixture of cinnamon twig and moutan root bark, cinnamon twig and peony root, or cinnamon twig and poria according to the present invention has been confirmed to inhibit the excessive generation of advanced glycation end-products, which occurs under chronic diabetic conditions, exhibit the effect of fragmentizing a cross-link between the advanced glycation end-products and matrix proteins, have an excellent effect in inhibiting the generation of the advanced glycation end-products in a human retinal pigment epithelial cell line subjected to a hyperglycemic or aging environment, and have excellent effects in delaying, preventing, and treating diabetic complications, muscular degeneration, commotio retinae, and lower extremity edema in various animal models of diabetic complications, macular degeneration, and lower extremity edema, and thus the mixture extract can effectively be used as an active ingredient for a composition for preventing and treating diabetic complications, including diabetic

Abstract: The present invention relates to a biomarker for predicting immunotherapy responsiveness in a patient with lung cancer and a use thereof, and more specifically, to a marker composition for predicting immunotherapy responsiveness in a patient with lung adenocarcinoma, a composition for predicting immunotherapy responsiveness, and a method for providing information for predicting immunotherapy responsiveness, comprising a CXCL13 gene or a protein encoded by the gene, and it was confirmed that CXCL3 was significantly upregulated in a patient administered an immune checkpoint inhibitor using the composition of the present invention, and through this, the CXCL13 gene or the protein encoded by the gene may be usefully used as a marker for predicting anticancer drug therapy responsiveness against lung cancer in related research fields, and is expected to be utilized as an immunotherapeutic adjuvant which enhances the anticancer treatment effect by developing an enhancer.

Abstract: A method of controlling a cooking apparatus includes a cleaning process which includes controlling a temperature in a cooking chamber such that the temperature in the cooking chamber is maintained at a preset first temperature for a preset first time, and controlling a temperature in a cooking chamber such that the temperature in the cooking chamber is maintained at a preset second temperature higher than the first temperature for a preset second time.

Abstract: The present invention relates to a prebiotic composition, a composition for improving gut microorganisms, a composition for improving gut health or gut function, a composition for alleviating, preventing, or treating inflammatory bowel disease or leaky gut syndrome, or a composition for alleviating, preventing, or treating obesity or metabolic disease, which each comprise a molokhia extract or a molokhia polymer fraction as an active ingredient to induce the proliferation of beneficial intestinal bacteria and to improve, prevent, or treat gut heath or gut function. In addition, the composition comprising a molokhia extract or a molokhia polymer fraction as an active ingredient can alleviate, prevent, or treat bowel disease or leaky gut syndrome.

Abstract: The present invention relates to an apicidin composition for inducing differentiation of mesenchymal stem cells into cardiac-committed cells, and a method for inducing differentiation into cardiac-committed cells using the same. The present invention allows mesenchymal stem cells to be specifically induced to differentiate into cardiac-committed cells even when an apicidin is treated for only a very short period of time of 24 hours, thereby being capable of solving the extremely low cardiomyogenic differentiation efficiency of mesenchymal stem cells, high cost, and long-term problems in the conventional art, and thus the present invention can be usefully used for treating heart disease.

Abstract: A urinary incontinence prevention clip for men includes: a clip body having an upper frame positioned so as to correspond to the upper part of male genitalia, a lower frame positioned so as to correspond to the lower part of the male genitalia, and a connection part connected to one side of the upper frame and the lower frame and providing elastic force in a direction, in which the upper frame and the lower frame are spread; cushion parts respectively provided on the inside of the upper frame and the inside of the lower frame; and locking parts formed at both ends of the clip body so as to be fastened to each other, wherein the upper frame is formed so as not to press the blood vessels of the male genitalia and the lower frame is formed so as to press the urethras of the male genitalia.

Abstract: Disclosed is a method for producing soluble CRM197 protein at high yield by overexpressing the protein in the cytoplasm of E. coli. The method includes a step of culturing recombinant E. coli harboring an expression plasmid carrying a gene sequence coding for a recombinant CRM197 protein under a condition suitable for expression of the recombinant CRM197 protein which has a histidine-tag attached to the C-terminus of CRM197 and a maltose-binding protein (MBP) attached to the N-terminus of CRM197. The method further includes a step of purifying after the culturing, wherein the step of purifying comprises a step of treating with tobacco etch virus (TEV) protease to remove the maltose-binding protein and a step of removing the histidine-tag via histidine-tag affinity chromatography.

Abstract: A method of controlling a cooking apparatus, comprising a cleaning process comprising controlling a temperature in a cooking chamber such that the temperature in the cooking chamber is maintained at a preset first temperature for a preset first time, and controlling a temperature in a cooking chamber such that the temperature in the cooking chamber is maintained at a preset second temperature higher than the first temperature for a preset second time. A cooking apparatus comprising, a main body having a cooking chamber formed therein, a convection flow unit comprising a convection heater to heat air in the cooking chamber and a convection fan to circulate the air in the cooking chamber, and a metal foam installed at a periphery of the convection flow unit to collect and decompose cooking gas contained in the air in the cooking chamber.

Abstract: The present disclosure relates to a connecting core for column-beam joint, the connecting core being able to secure excellent rigidity through a simple process without welding. To this end, a connecting core for column-beam joint includes: a closed-section intermediate column; a diaphragm; and internal reinforcing members, in which slit for inserting the internal reinforcing members are formed at the diaphragm, and the internal reinforcing members inserted in the diaphragm are combined with the intermediate column. According to the present disclosure, high rigidity is secured, as compared with the related art, when a closed-section column and a beam are connected. Further, a closed-section column and a beam can be connected without welding, so the process can be shortened, connecting become easy, and quality is also uniform.