Abstract: This invention relates to an apparatus and a method for the production of outwardly ribbed, plastic pipes. The apparatus includes a core around which a plasticized material is pressed from a nozzle. A kernel having an essentially constant diameter is positioned at the terminal end of the core for a smooth inner face of the pipe. The outer face of the pipe is ribbed by grooves of axially displaceable chill moulds. The end zone of the kernel is provided for the cooling of the inner face of the pipe. In known apparatuses the grooves of the chill moulds are often filled incompletely and the inner face of the pipe becomes uneven on account of air bubbles, for instance. These disadvantages are avoided by heating an initial zone of the kernel for heating the inner face of the pipe and by shaping the surface of the initial zone to slightly expand conicallly in the production direction.

Abstract: A method for inducing increased inotropic effects of the human heart without inducing arrhythmogenic effects, but providing an antiarrhythmogenic effect therein. The method is effected by administering to mammals, including man, a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen or ##STR2## wherein R' is selected from the group consisting of straight or branched aliphatic alkyl having 1 to 7 carbon atoms, phenyl, benzyl, and phenylethyl, wherein the phenyl nucleus may be further substituted with alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, alkoxyalkyl having 2 to 8 carbon atoms or halogen, in any position.

Abstract: New amines of the formula ##STR1## wherein the radicals R.sup.1, R.sup.2 and R.sup.3 may be any of a variety of groups described below, several methods for preparing them and the use thereof in the treatment of cardiovascular diseases, particularly in blocking cardial and vascular beta-receptors.

Abstract: The invention concerns peptides having the general formula X--Glu--His--Phe--Arg--Trp--Gly--Lys--Pro--Val--Gly--Lys--Lys--Y--NH.sub.2 wherein X represents alkyloxy carbonyl, aryl alkyloxy carbonyl or D-Ser-Met, and Y represents a residue of n diaminomonocarboxylic acids, n being an integer of 2-4, and a method of producing the same.

Abstract: Compounds having the structure ##STR1## AS WELL AS PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A METHOD OF INHIBITING THE GASTRIC ACID SECRETION BY ADMINISTERING THEM.

Abstract: Compounds having the structural formula ##STR1## PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND THE USE THEREOF FOR AFFECTING GASTRIC ACID SECRETION; INTERMEDIATE PRODUCTS HAVING THE STRUCTURAL FORMULA ##STR2## AND METHODS FOR PREPARING THE SAME.

Abstract: New amines of the formula ##STR1## wherein the radicals R.sup.1, R.sup.2 and R.sup.3 may be any of a variety of groups described below, several methods for preparing them and the use thereof in the treatment of cardiovascular diseases, particularly in blocking cardial and vascular beta-receptors.

Abstract: Para-substituted phenoxy-hydroxypropylamines having the general formula ##STR1## and pharmaceutically acceptable, non-toxic acid addition salts thereof, wherein R' is an isopropyl or tertiarybutyl radical; Z is a member selected from the group consisting of -OR", -SR", and -NHCOOR", R" being a straight or branched lower alkyl radical having 1 to 3 carbon atoms; and n is 1, 2, or 3, are disclosed as are methods for their preparation. Pharmaceutical preparations are prepared whose active ingredients include at least one of the newly discovered phenoxy-hydroxypropylamine compounds. Therapeutically effective doses of these preparations selectively block the .beta.-receptors of the heart making them useful in treating heart diseases in animals including humans.

Abstract: Ortho-para-substituted phenoxy-hydroxypropylamines having the general formula ##STR1## and pharmaceutically acceptable, non-toxic acid addition salts thereof, wherein R.sup.1 is alkyl or hydroxy alkyl, R.sup.2 is alkoxyalkyl, alkylthioalkyl, alkoxycarbonylaminoalkyl, or alkoxyalkoxy, and R.sup.3 is halogen, alkyl, alkenyl, alkinyl, alkoxymethyl, or alkoxy are disclosed as are methods for their preparations;Pharmaceutical preparations are prepared whose active ingredients include at least one of the newly discovered phenoxy-hydroxypropylamine compounds. Therapeutically effective doses of these preparations selectively block the .beta.-receptors of the heart making them useful in treating heart diseases in animals including humans.

Abstract: An apparatus for handling, loading, unloading and transporting containers, load supporting bodies, pallets and like bulky and heavy objects with the use of a transport vehicle and a fork lift type lifting device disposed on the transport vehicle. The fork lift device is pivoted to one end of the transport vehicle in such a way that the frame carrying the fork lift device can be pivoted between a vertical position and a position coplanar with the chassis of the transport vehicle. Coupling means associated with the fork lift device is designed so as to permit being coupled with mating coupling means associated with the end of a load supporting body which is usable as a transportation support for containers and like objects. When the load supporting body is coupled with the fork lift device, the body can be pulled onto and lowered from the transport vehicle under simultaneous pivotment of the frame of the fork lift device and shifting of the fork lift device along the frame thereof.