Patents by Inventor Ira Spool
Ira Spool has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230386685Abstract: An aspect of the present disclosure includes a fusion reactor including a reactor housing extending in an axial direction from a first end to a second end, wherein the reactor housing includes a first port, a second port, a fluid communication port, and a charged particle source delivery port, a fuel hopper located within the reactor housing proximal to the first end, an outlet located within the reactor housing proximal to the second end, a plurality of magnetic field generating coils located about the reactor housing, wherein the plurality of magnetic field generating coils are oriented to produce a directional magnetic field within the reactor housing, a plurality of electrodes extending within the reactor housing from the first end to the second end, wherein the plurality of electrodes are configured to generate a plurality time-varying electric fields via an electrical source.Type: ApplicationFiled: February 9, 2023Publication date: November 30, 2023Inventors: Ara KNAIAN, Nathaniel MACFADDEN, Demetrious HARRINGTON, Ira SPOOL
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Patent number: 11660054Abstract: Embodiments related to methods and wearable medical detecting systems for detecting disease states and/or treatment states of a subject are described. In one embodiment, a wearable structure may include one or more radiation detectors use to detect a time varying radiation signal emitted from a labeled compound within a body portion of interest. The radiation signal may be analyzed to determine one or more signal characteristics that may be compared to one or more predetermined standard characteristics associated with known disease and/or treatment states to determine a current disease and/or treatment state of a subject.Type: GrantFiled: November 22, 2017Date of Patent: May 30, 2023Assignee: Biogen MA Inc.Inventors: Ajay Verma, Elliot Greenblatt, Ira Spool, Seth O. Newburg, Guy M. Danner, Ara N. Knaian, Rachel M. Chaney, John W. Hoppin
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Patent number: 11103634Abstract: An assembly for storing both new and used pen needles of an injection apparatus, comprising a plurality of storage units each configured to store a pen needle having a needle fixed to a hub, the plurality of storage units being hingedly connected, and each including a storage end, and a dispensing end having an anti-rotation structure, wherein the anti-rotation structure working in conjunction with the hub of the pen needle to prevent rotation of the pen needle when the pen needle is in a dispensing position.Type: GrantFiled: October 24, 2018Date of Patent: August 31, 2021Assignee: Becton, Dickinson and CompanyInventors: Ira Spool, Cole Constantineau, Ryan Schoonmaker, Sean P. Sullivan, Abhijitsinh Raj, Michel Bruehwiler
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Patent number: 10939989Abstract: The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e).Type: GrantFiled: November 1, 2017Date of Patent: March 9, 2021Assignees: The General Hospital Corporation, The Charles Stark Draper Laboratory, Inc.Inventors: David M. Hoganson, Howard I. Pryor, Ira Spool, Joseph P. Vacanti, Jeffrey T. Borenstein
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Patent number: 10632621Abstract: A robotic grommet installer includes a robotic arm and an installation unit. The installation unit includes a rotary grommet holder rotatively coupled to the robotic arm and an installer coupled to the robotic arm. The rotary grommet holder includes a plurality of grommet chambers spaced circumferentially about a rotational axis of the rotary grommet holder. Each grommet chamber of the plurality of grommet chambers is configured to hold a plurality of grommets. The installer is configured to retrieve a grommet from the rotary grommet holder, wherein the rotary grommet holder is configured to rotate to align the installer with an available grommet positioned within one of the plurality of grommet chambers.Type: GrantFiled: October 11, 2018Date of Patent: April 28, 2020Assignee: TOYOTA RESEARCH INSTITUTE, INC.Inventors: Erik C. Sobel, Calder Phillips-Grafflin, Aimee Goncalves, Guy Danner, Ira Spool, Jonathan Kalow, Nicholas Brennan, Seth Newburg, Joseph Fenton
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Publication number: 20190389598Abstract: Embodiments of systems, devices, and methods are described that relate to module structures for use in forming a cabin interior of an aircraft. Many embodiments relate to a support structure including a lattice configurable to provide a standardizable frame for connection to the interior of the aircraft and to provide a space within the frame in which module fixtures can be positioned and secured to the frame. Embodiments of the support structure can include a floor with a number of structures and devices that can be used to provide support for the module and secure the module to the floor of the aircraft fuselage. Embodiments of transport systems for the modules are also described and such can be integrated with the floor of the module such that the modules transport mechanism, or a significant portion thereof, is contained within the module itself.Type: ApplicationFiled: September 4, 2019Publication date: December 26, 2019Inventors: Jason Lim Chua, Martin Sieben, Angelica Cardona, Guy M. Danner, Joseph Fenton, Demetrious Harrington, Shahriar Khushrushahi, Elena Koukina, Seth Newburg, Ira Spool, Hugo Jamson, Luke Miles, Justin Almeleh, Alex Herpy, Matt O'Brien, Zachary Omohundro, Edward Smith
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Publication number: 20190321982Abstract: A robotic grommet installer includes a robotic arm and an installation unit. The installation unit includes a rotary grommet holder rotatively coupled to the robotic arm and an installer coupled to the robotic arm. The rotary grommet holder includes a plurality of grommet chambers spaced circumferentially about a rotational axis of the rotary grommet holder. Each grommet chamber of the plurality of grommet chambers is configured to hold a plurality of grommets. The installer is configured to retrieve a grommet from the rotary grommet holder, wherein the rotary grommet holder is configured to rotate to align the installer with an available grommet positioned within one of the plurality of grommet chambers.Type: ApplicationFiled: October 11, 2018Publication date: October 24, 2019Applicant: Toyota Research Institute, Inc.Inventors: Erik C. Sobel, Calder Phillips-Grafflin, Aimee Goncalves, Guy Danner, Ira Spool, Jonathan Kalow, Nicholas Brennan, Seth Newburg, Joseph Fenton
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Publication number: 20190320989Abstract: Embodiments related to methods and wearable medical detecting systems for detecting disease states and/or treatment states of a subject are described. In one embodiment, a wearable structure may include one or more radiation detectors use to detect a time varying radiation signal emitted from a labeled compound within a body portion of interest. The radiation signal may be analyzed to determine one or more signal characteristics that may be compared to one or more predetermined standard characteristics associated with known disease and/or treatment states to determine a current disease and/or treatment state of a subject.Type: ApplicationFiled: November 22, 2017Publication date: October 24, 2019Applicant: Biogen MA Inc.Inventors: Ajay Verma, Elliot Greenblatt, Ira Spool, Seth O. Newburg, Guy M. Danner, Ara N. Knaian, Rachel M. Chaney
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Patent number: 10327885Abstract: The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e).Type: GrantFiled: February 6, 2015Date of Patent: June 25, 2019Assignees: The General Hospital Corporation, The Charles Stark Draper LaboratoryInventors: David M. Hoganson, Howard I. Pryor, Ira Spool, Joseph P. Vacanti, Jeffrey T. Borenstein
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Patent number: 10258749Abstract: A dual-chambered drug delivery device, comprising a cartridge having a first chamber for storing a medicament, a second chamber in fluid communication with said first chamber, a dose setting member for setting a medicament dose to be injected at an injection site, a piston disposed in said second chamber, an upward stroke of said piston drawing a portion of the medicament dose into said second chamber and a downward stroke of said piston expelling the portion of the medicament dose, a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site, a drive screw movably connected to said dose setting member such that rotation of said dose setting member moves said drive screw upwardly, and a rack movably connected to said drive screw such that downward movement of said drive screw during the medicament dose injection rotates said rack.Type: GrantFiled: December 8, 2015Date of Patent: April 16, 2019Assignee: Becton, Dickinson and CompanyInventors: Ryan Schoonmaker, Michel Bruehwiler, Ira Spool, Melissa Rosen
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Patent number: 10213553Abstract: A method of delivering high pressure medication injections, the method comprising storing a medicament in a cartridge, engaging a lever gear in a lever assembly to a rack, rotating a lever arm in said lever assembly that is connected to said lever gear, moving said rack to move a stopper through said cartridge upon rotation of said lever arm, expelling a medicament dose from said cartridge via movement of said stopper, and injecting said medicament dose through a needle that communicates with said cartridge.Type: GrantFiled: August 12, 2016Date of Patent: February 26, 2019Assignee: Becton, Dickinson and CompanyInventors: Ira Spool, Michel Bruehwiler, Ryan Schoonmaker, Melissa Rosen
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Publication number: 20190054231Abstract: An assembly for storing both new and used pen needles of an injection apparatus, comprising a plurality of storage units each configured to store a pen needle having a needle fixed to a hub, the plurality of storage units being hingedly connected, and each including a storage end, and a dispensing end having an anti-rotation structure, wherein the anti-rotation structure working in conjunction with the hub of the pen needle to prevent rotation of the pen needle when the pen needle is in a dispensing position.Type: ApplicationFiled: October 24, 2018Publication date: February 21, 2019Applicant: Becton, Dickinson and CompanyInventors: Ira Spool, Cole Constantineau, Ryan Schoonmaker, Sean P. Sullivan, Abhijitsinh Raj, Michel Bruehwiler
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Patent number: 10137238Abstract: A flip-open multi-pack assembly which contains a plurality of new pen needles via a rectangular or tube-shaped, hinged shell housing, wherein new pen needles are stored in a plurality of user accessible openings each having a sterility barrier formed by covers that cover the non-patient end of the openings where the new pen needles are contained. Used pen needles are returned and stored in openings accessible by rotatably opening the shell housing. One or more of the openings within first and second opposite ends of the housing shell include a slidable internal holder configured to releasably secure the inner shield of the new pen needle, and subsequently be pulled forward when the new pen needle is removed and locked at a forward position, to create an interior space, accessible from an opposite end when the hinged housing is opened, for a used pen needle to be inserted and stored.Type: GrantFiled: November 23, 2015Date of Patent: November 27, 2018Assignee: Becton, Dickinson and CompanyInventors: Ira Spool, Cole Constantineau, Ryan Schoonmaker, Sean P. Sullivan, Abhijitsinh Raj, Michel Bruehwiler
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Publication number: 20180256312Abstract: The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e).Type: ApplicationFiled: November 1, 2017Publication date: September 13, 2018Inventors: David M. Hoganson, Howard I. Pryor, Ira Spool, Joseph P. Vacanti, Jeffrey T. Borenstein
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Publication number: 20160346474Abstract: A method of delivering high pressure medication injections, the method comprising storing a medicament in a cartridge, engaging a lever gear in a lever assembly to a rack, rotating a lever arm in said lever assembly that is connected to said lever gear, moving said rack to move a stopper through said cartridge upon rotation of said lever arm, expelling a medicament dose from said cartridge via movement of said stopper, and injecting said medicament dose through a needle that communicates with said cartridge.Type: ApplicationFiled: August 12, 2016Publication date: December 1, 2016Applicant: Becton, Dickinson and CompanyInventors: Ira Spool, Michel Bruehwiler, Ryan Schoonmaker, Melissa Rosen
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Patent number: 9446200Abstract: A drug delivery device includes a cartridge (211) for storing a medicament and a needle (203) communicating with the cartridge (211) for injecting a medicament dose. A rack (241) is movably disposed in the cartridge (211) and is engageable with a stopper (213) for expelling the medicament dose from the cartridge (211). A lever assembly (231) has a lever arm (233) connected to a lever gear (230). The lever gear (232) is engaged with the rack (241) such that rotation of the lever arm (233) rotates the lever gear (232) during injection of the medicament dose, thereby moving the rack (241) and stopper (213) through the cartridge (211) to deliver the medicament dose.Type: GrantFiled: December 8, 2009Date of Patent: September 20, 2016Assignee: Becton, Dickinson and CompanyInventors: Ira Spool, Michel Bruehwiler, Ryan Schoonmaker, Melissa Rosen
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Patent number: 9408980Abstract: A dual-chambered drug delivery device (201) includes a first chamber (205) in which a medicament is stored. A dose setting member (213) is rotated to set a medicament dose. The dose setting member (213) being rotatable to set the medicament dose. The dose setting member (213) is not axially moveable. A second chamber (221) is in fluid communication with the first chamber (205). The medicament dose is transferred to the second chamber (221) from the first chamber (205) prior to injecting the medicament dose. A needle (203) communicates with the second chamber (221) to inject the medicament dose into an injection site.Type: GrantFiled: December 8, 2009Date of Patent: August 9, 2016Assignee: Becton, Dickinson and CompanyInventors: Michel Bruehwiler, Melissa Rosen, Ryan Schoonmaker, Ira Spool
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Publication number: 20160158462Abstract: A dual-chambered drug delivery device, comprising a cartridge having a first chamber for storing a medicament, a second chamber in fluid communication with said first chamber, a dose setting member for setting a medicament dose to be injected at an injection site, a piston disposed in said second chamber, an upward stroke of said piston drawing a portion of the medicament dose into said second chamber and a downward stroke of said piston expelling the portion of the medicament dose, a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site, a drive screw movably connected to said dose setting member such that rotation of said dose setting member moves said drive screw upwardly, and a rack movably connected to said drive screw such that downward movement of said drive screw during the medicament dose injection rotates said rack.Type: ApplicationFiled: December 8, 2015Publication date: June 9, 2016Applicant: Becton, Dickinson and CompanyInventors: Ryan SCHOONMAKER, Michel BRUEHWILER, Ira SPOOL, Melissa ROSEN
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Publication number: 20160074572Abstract: A flip-open multi-pack assembly is provided which can contain a plurality of new pen needles, such as through the provision of a rectangular or tube-shaped shaped, hinged shell housing, wherein new pen needles can be stored in a plurality of user accessible openings each having a sterility barrier formed, for example, by covers that cover the non-patient end of the openings in which the new pen needles are contained. Used pen needles can be returned and stored in openings accessible by rotatably opening the shell housing. One or more of the openings within first and second opposite ends of the housing shell can be provided with a slidable internal holder within the device and are configured to releasably secure the inner shield of the new pen needle, and to then be pulled forward when the new pen needle is removed and lock at a forward position, and thereby create an interior space, accessible from an opposite end when the hinged housing is opened, for a used pen needle to be inserted and stored.Type: ApplicationFiled: November 23, 2015Publication date: March 17, 2016Applicant: Becton, Dickinson and CompanyInventors: Ira Spool, Cole Constantineau, Ryan Schoonmaker, Sean P. Sullivan, Abhijitsinh Raj, Michel Bruehwiler
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Patent number: 9238112Abstract: A dual-chambered drug delivery device (201) includes a cartridge (211) having a first chamber (212) for storing a medicament and a second chamber (211) in fluid communication with the first chamber (212). A dose setting member (241) is used to set a medicament dose to be injected at an injection site. A piston (281) is disposed in the second chamber (221). An upward stroke of the piston (281) draw a portion of the medicament dose into the second chamber (221) and a downward stroke of the piston (281) expels the portion of the medicament dose. A needle (205) communicates with the second chamber (221) for sequentially injecting the portions of the medicament dose into the injection site.Type: GrantFiled: December 8, 2009Date of Patent: January 19, 2016Assignee: Becton, Dickinson and CompanyInventors: Ryan Schoonmaker, Michel Bruehwiler, Ira Spool, Melissa Rosen