Patents by Inventor Ira Spool

Ira Spool has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230386685
    Abstract: An aspect of the present disclosure includes a fusion reactor including a reactor housing extending in an axial direction from a first end to a second end, wherein the reactor housing includes a first port, a second port, a fluid communication port, and a charged particle source delivery port, a fuel hopper located within the reactor housing proximal to the first end, an outlet located within the reactor housing proximal to the second end, a plurality of magnetic field generating coils located about the reactor housing, wherein the plurality of magnetic field generating coils are oriented to produce a directional magnetic field within the reactor housing, a plurality of electrodes extending within the reactor housing from the first end to the second end, wherein the plurality of electrodes are configured to generate a plurality time-varying electric fields via an electrical source.
    Type: Application
    Filed: February 9, 2023
    Publication date: November 30, 2023
    Inventors: Ara KNAIAN, Nathaniel MACFADDEN, Demetrious HARRINGTON, Ira SPOOL
  • Patent number: 11660054
    Abstract: Embodiments related to methods and wearable medical detecting systems for detecting disease states and/or treatment states of a subject are described. In one embodiment, a wearable structure may include one or more radiation detectors use to detect a time varying radiation signal emitted from a labeled compound within a body portion of interest. The radiation signal may be analyzed to determine one or more signal characteristics that may be compared to one or more predetermined standard characteristics associated with known disease and/or treatment states to determine a current disease and/or treatment state of a subject.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: May 30, 2023
    Assignee: Biogen MA Inc.
    Inventors: Ajay Verma, Elliot Greenblatt, Ira Spool, Seth O. Newburg, Guy M. Danner, Ara N. Knaian, Rachel M. Chaney, John W. Hoppin
  • Patent number: 11103634
    Abstract: An assembly for storing both new and used pen needles of an injection apparatus, comprising a plurality of storage units each configured to store a pen needle having a needle fixed to a hub, the plurality of storage units being hingedly connected, and each including a storage end, and a dispensing end having an anti-rotation structure, wherein the anti-rotation structure working in conjunction with the hub of the pen needle to prevent rotation of the pen needle when the pen needle is in a dispensing position.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: August 31, 2021
    Assignee: Becton, Dickinson and Company
    Inventors: Ira Spool, Cole Constantineau, Ryan Schoonmaker, Sean P. Sullivan, Abhijitsinh Raj, Michel Bruehwiler
  • Patent number: 10939989
    Abstract: The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e).
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: March 9, 2021
    Assignees: The General Hospital Corporation, The Charles Stark Draper Laboratory, Inc.
    Inventors: David M. Hoganson, Howard I. Pryor, Ira Spool, Joseph P. Vacanti, Jeffrey T. Borenstein
  • Patent number: 10632621
    Abstract: A robotic grommet installer includes a robotic arm and an installation unit. The installation unit includes a rotary grommet holder rotatively coupled to the robotic arm and an installer coupled to the robotic arm. The rotary grommet holder includes a plurality of grommet chambers spaced circumferentially about a rotational axis of the rotary grommet holder. Each grommet chamber of the plurality of grommet chambers is configured to hold a plurality of grommets. The installer is configured to retrieve a grommet from the rotary grommet holder, wherein the rotary grommet holder is configured to rotate to align the installer with an available grommet positioned within one of the plurality of grommet chambers.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: April 28, 2020
    Assignee: TOYOTA RESEARCH INSTITUTE, INC.
    Inventors: Erik C. Sobel, Calder Phillips-Grafflin, Aimee Goncalves, Guy Danner, Ira Spool, Jonathan Kalow, Nicholas Brennan, Seth Newburg, Joseph Fenton
  • Publication number: 20190389598
    Abstract: Embodiments of systems, devices, and methods are described that relate to module structures for use in forming a cabin interior of an aircraft. Many embodiments relate to a support structure including a lattice configurable to provide a standardizable frame for connection to the interior of the aircraft and to provide a space within the frame in which module fixtures can be positioned and secured to the frame. Embodiments of the support structure can include a floor with a number of structures and devices that can be used to provide support for the module and secure the module to the floor of the aircraft fuselage. Embodiments of transport systems for the modules are also described and such can be integrated with the floor of the module such that the modules transport mechanism, or a significant portion thereof, is contained within the module itself.
    Type: Application
    Filed: September 4, 2019
    Publication date: December 26, 2019
    Inventors: Jason Lim Chua, Martin Sieben, Angelica Cardona, Guy M. Danner, Joseph Fenton, Demetrious Harrington, Shahriar Khushrushahi, Elena Koukina, Seth Newburg, Ira Spool, Hugo Jamson, Luke Miles, Justin Almeleh, Alex Herpy, Matt O'Brien, Zachary Omohundro, Edward Smith
  • Publication number: 20190321982
    Abstract: A robotic grommet installer includes a robotic arm and an installation unit. The installation unit includes a rotary grommet holder rotatively coupled to the robotic arm and an installer coupled to the robotic arm. The rotary grommet holder includes a plurality of grommet chambers spaced circumferentially about a rotational axis of the rotary grommet holder. Each grommet chamber of the plurality of grommet chambers is configured to hold a plurality of grommets. The installer is configured to retrieve a grommet from the rotary grommet holder, wherein the rotary grommet holder is configured to rotate to align the installer with an available grommet positioned within one of the plurality of grommet chambers.
    Type: Application
    Filed: October 11, 2018
    Publication date: October 24, 2019
    Applicant: Toyota Research Institute, Inc.
    Inventors: Erik C. Sobel, Calder Phillips-Grafflin, Aimee Goncalves, Guy Danner, Ira Spool, Jonathan Kalow, Nicholas Brennan, Seth Newburg, Joseph Fenton
  • Publication number: 20190320989
    Abstract: Embodiments related to methods and wearable medical detecting systems for detecting disease states and/or treatment states of a subject are described. In one embodiment, a wearable structure may include one or more radiation detectors use to detect a time varying radiation signal emitted from a labeled compound within a body portion of interest. The radiation signal may be analyzed to determine one or more signal characteristics that may be compared to one or more predetermined standard characteristics associated with known disease and/or treatment states to determine a current disease and/or treatment state of a subject.
    Type: Application
    Filed: November 22, 2017
    Publication date: October 24, 2019
    Applicant: Biogen MA Inc.
    Inventors: Ajay Verma, Elliot Greenblatt, Ira Spool, Seth O. Newburg, Guy M. Danner, Ara N. Knaian, Rachel M. Chaney
  • Patent number: 10327885
    Abstract: The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e).
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: June 25, 2019
    Assignees: The General Hospital Corporation, The Charles Stark Draper Laboratory
    Inventors: David M. Hoganson, Howard I. Pryor, Ira Spool, Joseph P. Vacanti, Jeffrey T. Borenstein
  • Patent number: 10258749
    Abstract: A dual-chambered drug delivery device, comprising a cartridge having a first chamber for storing a medicament, a second chamber in fluid communication with said first chamber, a dose setting member for setting a medicament dose to be injected at an injection site, a piston disposed in said second chamber, an upward stroke of said piston drawing a portion of the medicament dose into said second chamber and a downward stroke of said piston expelling the portion of the medicament dose, a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site, a drive screw movably connected to said dose setting member such that rotation of said dose setting member moves said drive screw upwardly, and a rack movably connected to said drive screw such that downward movement of said drive screw during the medicament dose injection rotates said rack.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: April 16, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Ryan Schoonmaker, Michel Bruehwiler, Ira Spool, Melissa Rosen
  • Patent number: 10213553
    Abstract: A method of delivering high pressure medication injections, the method comprising storing a medicament in a cartridge, engaging a lever gear in a lever assembly to a rack, rotating a lever arm in said lever assembly that is connected to said lever gear, moving said rack to move a stopper through said cartridge upon rotation of said lever arm, expelling a medicament dose from said cartridge via movement of said stopper, and injecting said medicament dose through a needle that communicates with said cartridge.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: February 26, 2019
    Assignee: Becton, Dickinson and Company
    Inventors: Ira Spool, Michel Bruehwiler, Ryan Schoonmaker, Melissa Rosen
  • Publication number: 20190054231
    Abstract: An assembly for storing both new and used pen needles of an injection apparatus, comprising a plurality of storage units each configured to store a pen needle having a needle fixed to a hub, the plurality of storage units being hingedly connected, and each including a storage end, and a dispensing end having an anti-rotation structure, wherein the anti-rotation structure working in conjunction with the hub of the pen needle to prevent rotation of the pen needle when the pen needle is in a dispensing position.
    Type: Application
    Filed: October 24, 2018
    Publication date: February 21, 2019
    Applicant: Becton, Dickinson and Company
    Inventors: Ira Spool, Cole Constantineau, Ryan Schoonmaker, Sean P. Sullivan, Abhijitsinh Raj, Michel Bruehwiler
  • Patent number: 10137238
    Abstract: A flip-open multi-pack assembly which contains a plurality of new pen needles via a rectangular or tube-shaped, hinged shell housing, wherein new pen needles are stored in a plurality of user accessible openings each having a sterility barrier formed by covers that cover the non-patient end of the openings where the new pen needles are contained. Used pen needles are returned and stored in openings accessible by rotatably opening the shell housing. One or more of the openings within first and second opposite ends of the housing shell include a slidable internal holder configured to releasably secure the inner shield of the new pen needle, and subsequently be pulled forward when the new pen needle is removed and locked at a forward position, to create an interior space, accessible from an opposite end when the hinged housing is opened, for a used pen needle to be inserted and stored.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: November 27, 2018
    Assignee: Becton, Dickinson and Company
    Inventors: Ira Spool, Cole Constantineau, Ryan Schoonmaker, Sean P. Sullivan, Abhijitsinh Raj, Michel Bruehwiler
  • Publication number: 20180256312
    Abstract: The invention provides method of fabricating a scaffold comprising a fluidic network, including the steps of: (a) generating an initial vascular layer for enclosing the chamber and providing fluid to the cells, the initial vascular layer having a network of channels for fluid; (b) translating the initial vascular layer into a model for fluid dynamics analysis; (c) analyzing the initial vascular layer based on desired parameters selected from the group consisting of a characteristic of a specific fluid, an input pressure, an output pressure, an overall flow rate and combinations thereof to determine sheer stress and velocity within the network of channels; (d) measuring the sheer stress and the velocity and comparing the obtained values to predetermined values; (e) determining if either of the shear stress or the velocity are greater than or less than the predetermined values, and (f) optionally modifying the initial vascular layer and repeating steps (b)-(e).
    Type: Application
    Filed: November 1, 2017
    Publication date: September 13, 2018
    Inventors: David M. Hoganson, Howard I. Pryor, Ira Spool, Joseph P. Vacanti, Jeffrey T. Borenstein
  • Publication number: 20160346474
    Abstract: A method of delivering high pressure medication injections, the method comprising storing a medicament in a cartridge, engaging a lever gear in a lever assembly to a rack, rotating a lever arm in said lever assembly that is connected to said lever gear, moving said rack to move a stopper through said cartridge upon rotation of said lever arm, expelling a medicament dose from said cartridge via movement of said stopper, and injecting said medicament dose through a needle that communicates with said cartridge.
    Type: Application
    Filed: August 12, 2016
    Publication date: December 1, 2016
    Applicant: Becton, Dickinson and Company
    Inventors: Ira Spool, Michel Bruehwiler, Ryan Schoonmaker, Melissa Rosen
  • Patent number: 9446200
    Abstract: A drug delivery device includes a cartridge (211) for storing a medicament and a needle (203) communicating with the cartridge (211) for injecting a medicament dose. A rack (241) is movably disposed in the cartridge (211) and is engageable with a stopper (213) for expelling the medicament dose from the cartridge (211). A lever assembly (231) has a lever arm (233) connected to a lever gear (230). The lever gear (232) is engaged with the rack (241) such that rotation of the lever arm (233) rotates the lever gear (232) during injection of the medicament dose, thereby moving the rack (241) and stopper (213) through the cartridge (211) to deliver the medicament dose.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: September 20, 2016
    Assignee: Becton, Dickinson and Company
    Inventors: Ira Spool, Michel Bruehwiler, Ryan Schoonmaker, Melissa Rosen
  • Patent number: 9408980
    Abstract: A dual-chambered drug delivery device (201) includes a first chamber (205) in which a medicament is stored. A dose setting member (213) is rotated to set a medicament dose. The dose setting member (213) being rotatable to set the medicament dose. The dose setting member (213) is not axially moveable. A second chamber (221) is in fluid communication with the first chamber (205). The medicament dose is transferred to the second chamber (221) from the first chamber (205) prior to injecting the medicament dose. A needle (203) communicates with the second chamber (221) to inject the medicament dose into an injection site.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: August 9, 2016
    Assignee: Becton, Dickinson and Company
    Inventors: Michel Bruehwiler, Melissa Rosen, Ryan Schoonmaker, Ira Spool
  • Publication number: 20160158462
    Abstract: A dual-chambered drug delivery device, comprising a cartridge having a first chamber for storing a medicament, a second chamber in fluid communication with said first chamber, a dose setting member for setting a medicament dose to be injected at an injection site, a piston disposed in said second chamber, an upward stroke of said piston drawing a portion of the medicament dose into said second chamber and a downward stroke of said piston expelling the portion of the medicament dose, a needle communicating with said second chamber for sequentially injecting portions of the medicament dose into the injection site, a drive screw movably connected to said dose setting member such that rotation of said dose setting member moves said drive screw upwardly, and a rack movably connected to said drive screw such that downward movement of said drive screw during the medicament dose injection rotates said rack.
    Type: Application
    Filed: December 8, 2015
    Publication date: June 9, 2016
    Applicant: Becton, Dickinson and Company
    Inventors: Ryan SCHOONMAKER, Michel BRUEHWILER, Ira SPOOL, Melissa ROSEN
  • Publication number: 20160074572
    Abstract: A flip-open multi-pack assembly is provided which can contain a plurality of new pen needles, such as through the provision of a rectangular or tube-shaped shaped, hinged shell housing, wherein new pen needles can be stored in a plurality of user accessible openings each having a sterility barrier formed, for example, by covers that cover the non-patient end of the openings in which the new pen needles are contained. Used pen needles can be returned and stored in openings accessible by rotatably opening the shell housing. One or more of the openings within first and second opposite ends of the housing shell can be provided with a slidable internal holder within the device and are configured to releasably secure the inner shield of the new pen needle, and to then be pulled forward when the new pen needle is removed and lock at a forward position, and thereby create an interior space, accessible from an opposite end when the hinged housing is opened, for a used pen needle to be inserted and stored.
    Type: Application
    Filed: November 23, 2015
    Publication date: March 17, 2016
    Applicant: Becton, Dickinson and Company
    Inventors: Ira Spool, Cole Constantineau, Ryan Schoonmaker, Sean P. Sullivan, Abhijitsinh Raj, Michel Bruehwiler
  • Patent number: 9238112
    Abstract: A dual-chambered drug delivery device (201) includes a cartridge (211) having a first chamber (212) for storing a medicament and a second chamber (211) in fluid communication with the first chamber (212). A dose setting member (241) is used to set a medicament dose to be injected at an injection site. A piston (281) is disposed in the second chamber (221). An upward stroke of the piston (281) draw a portion of the medicament dose into the second chamber (221) and a downward stroke of the piston (281) expels the portion of the medicament dose. A needle (205) communicates with the second chamber (221) for sequentially injecting the portions of the medicament dose into the injection site.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: January 19, 2016
    Assignee: Becton, Dickinson and Company
    Inventors: Ryan Schoonmaker, Michel Bruehwiler, Ira Spool, Melissa Rosen