Patents by Inventor Ish KUMAR

Ish KUMAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Endoglucanase variants
    Patent number: 8906689
    Abstract: The present invention relates to variant endoglucanases having improved thermoactivity, improved thermostability, and improved viscosity reduction activity over wild-type M. thermophila endoglucanase.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: December 9, 2014
    Assignee: Codexis, Inc.
    Inventors: Xiyun Zhang, Sachin Patil, Jie Yang, Ish Kumar Dhawan
  • NOVEL BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS
    Publication number: 20140134235
    Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Application
    Filed: October 14, 2013
    Publication date: May 15, 2014
    Applicant: DR. REDDY'S LABORATORIES LTD.
    Inventors: Anima BARUAH, Dibyendu DE, Ish Kumar KHANNA, Sivaram PILLARISETTI, Santanu MAITRA, Christopher W. ALEXANDER, Jennepalli SREENU, Indu Dagar, Shanavas Alikunju
  • Endoglucanases
    Patent number: 8663960
    Abstract: The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: March 4, 2014
    Assignee: Codexis, Inc.
    Inventors: Jie Yang, Andrew Shaw, Ish Kumar Dhawan, Onorato Campopiano, Kripa Rao
  • COMPOSITIONS AND METHODS FOR PRODUCTION OF FERMENTABLE SUGARS
    Publication number: 20130344541
    Abstract: The present application provides genetically modified fungal organisms that produce enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to glucose, enzyme mixtures produced by the genetically modified fungal organisms, and processes for producing glucose from cellulose using such enzyme mixtures.
    Type: Application
    Filed: November 1, 2011
    Publication date: December 26, 2013
    Applicant: CODEXIS, INC.
    Inventors: Ish Kumar Dhawan, Dipnath Baidyaroy, Andrew Shaw, Oleh Tanchak, Christopher Hill, Chengsong Liu, Amala Chokshi, Brian R. Scott
  • Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
    Patent number: 8604055
    Abstract: The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: December 10, 2013
    Assignee: Dr. Reddy's Laboratories Ltd.
    Inventors: Anima Baruah, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti, Santanu Maitra, Christopher W. Alexander, Jennepalli Sreenu, Indu Dagar, Shanavas Alikunju
  • KAPPA OPIOID RECEPTOR AGONISTS
    Publication number: 20130303525
    Abstract: The present invention relates to a series of substituted compounds having the general formula (I), including their stereoisomers and/or their pharmaceutically acceptable salts. (I) Wherein A, m, R1s, R2, R3, R4 are as defined herein. This invention also relates to methods of making these compounds including intermediates. The compounds of this invention are effective at the kappa (?) opioid receptor (KOR) site. Therefore, the compounds of this invention are useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of central nervous system disorders (CNS), including but not limited to acute and chronic pain, and associated disorders, particularly functioning peripherally at the CNS.
    Type: Application
    Filed: July 19, 2011
    Publication date: November 14, 2013
    Applicants: DR. REDDY'S LABORATORIES, INC., DR. REDDY;S LABORATORIES LTD.
    Inventors: Pradip Kumar Sasmal, Vamsee Krishna Chintakunta, Vijay Potluri, Ish Kumar Khanna, Ashok Tehim, Mahaboobi Jaleel, Thomas Hogberg, Oystein Rist, Lisbeth Elster, Thomas Michael Frimurer, Lars-Ole Gerlach
  • Transaminase polypeptides
    Patent number: 8470564
    Abstract: The present disclosure provides engineered transaminase enzymes having improved properties as compared to a naturally occurring wild-type transaminase enzyme. Also provided are polynucleotides encoding the engineered transaminase enzymes, host cells capable of expressing the engineered transaminase enzymes, and methods of using the engineered transaminase enzymes to synthesize a variety of chiral compounds.
    Type: Grant
    Filed: January 8, 2010
    Date of Patent: June 25, 2013
    Assignee: Codexis, Inc.
    Inventors: Ish Kumar Dhawan, Gregory Miller, Xiyun Zhang
  • ENDOGLUCANASES
    Publication number: 20120315676
    Abstract: The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
    Type: Application
    Filed: June 11, 2012
    Publication date: December 13, 2012
    Applicant: Codexis, Inc.
    Inventors: Jie YANG, Andrew Shaw, Ish Kumar Dhawan, Onorato Campopiano, Kripa Rao
  • Compositions and methods for production of fermentable sugars
    Patent number: 8309328
    Abstract: The present application provides genetically modified fungal organisms that produce enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to glucose, enzyme mixtures produced by the genetically modified fungal organisms, and processes for producing glucose from cellulose using such enzyme mixtures.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: November 13, 2012
    Assignee: Codexis, Inc.
    Inventors: Ish Kumar Dhawan, Dipnath Baidyaroy, Andrew Shaw, Oleh Tanchak, Christopher Hill, Chengsong Liu, Amala Chokshi, Brian R. Scott
  • COMPOSITIONS AND METHODS FOR PRODUCTION OF FERMENTABLE SUGARS
    Publication number: 20120270278
    Abstract: The present application provides genetically modified fungal organisms that produce enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to glucose, enzyme mixtures produced by the genetically modified fungal organisms, and processes for producing glucose from cellulose using such enzyme mixtures.
    Type: Application
    Filed: July 2, 2012
    Publication date: October 25, 2012
    Applicant: CODEXIS, INC.
    Inventors: ISH KUMAR DHAWAN, DIPNATH BAIDYAROY, ANDREW SHAW, OLEH TANCHAK, CHRISTOPHER HILL, CHENGSONG LIU, AMALA CHOKSHI, BRIAN R. SCOTT
  • ENDOGLUCANASE VARIANTS
    Publication number: 20120208235
    Abstract: The present invention relates to variant endoglucanases having improved thermoactivity, improved thermostability, and improved viscosity reduction activity over wild-type M. thermophila endoglucanase.
    Type: Application
    Filed: December 20, 2011
    Publication date: August 16, 2012
    Applicant: Codexis, Inc.
    Inventors: Xiyun Zhang, Sachin Patil, Jie Yang, Ish Kumar Dhawan
  • Compositions and methods for production of fermentable sugars
    Patent number: 8236551
    Abstract: The present application provides genetically modified fungal organisms that produce enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to glucose, enzyme mixtures produced by the genetically modified fungal organisms, and processes for producing glucose from cellulose using such enzyme mixtures.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: August 7, 2012
    Assignee: Codexis, Inc.
    Inventors: Ish Kumar Dhawan, Dipnath Baidyaroy, Andrew Shaw, Oleh Tanchak, Christopher Hill, Chengsong Liu, Amala Chokshi, Brian R. Scott
  • ENDOGLUCANASES
    Publication number: 20120178132
    Abstract: The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
    Type: Application
    Filed: December 12, 2011
    Publication date: July 12, 2012
    Applicant: Codexis, Inc.
    Inventors: Jie Yang, Andrew Shaw, Ish Kumar Dhawan, Onorato Campopiano, Kripa Rao
  • Endoglucanases
    Patent number: 8206960
    Abstract: The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
    Type: Grant
    Filed: December 12, 2011
    Date of Patent: June 26, 2012
    Assignee: Codexis, Inc.
    Inventors: Jie Yang, Andrew Shaw, Ish Kumar Dhawan, Onorato Campopiano, Kripa Rao
  • FUNGAL STRAINS
    Publication number: 20120107880
    Abstract: The present invention provides improved fungal strains. In some embodiments, the improved fungal strains find use in hydrolyzing cellulosic material to glucose.
    Type: Application
    Filed: November 1, 2011
    Publication date: May 3, 2012
    Applicant: CODEXIS, INC.
    Inventors: Dipnath Baidyaroy, Ish Kumar Dhawan
  • COMPOSITIONS AND METHODS FOR PRODUCTION OF FERMENTABLE SUGARS
    Publication number: 20120107881
    Abstract: The present application provides genetically modified fungal organisms that produce enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to glucose, enzyme mixtures produced by the genetically modified fungal organisms, and processes for producing glucose from cellulose using such enzyme mixtures.
    Type: Application
    Filed: November 1, 2011
    Publication date: May 3, 2012
    Applicant: CODEXIS, INC.
    Inventors: Ish Kumar Dhawan, Dipnath Baidyaroy, Andrew Shaw, Oleh Tanchak, Christopher Hill, Chengsong Liu, Amala Chokshi, Brian R. Scott
  • MODIFIED RELEASE NIACIN PHARMACEUTICAL FORMULATIONS
    Publication number: 20120064161
    Abstract: Pharmaceutical formulations comprising niacin in a matrix comprising a hydrophobic polymer that modifies release of niacin.
    Type: Application
    Filed: November 18, 2011
    Publication date: March 15, 2012
    Applicants: DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
    Inventors: Rajesh Vooturi, Dhananjay Singare, Shantanu Yeshwant Damle, Pradeep Jairao Karatgi, Sesha Sai Marella, Harshal Prabhakar Bhagwatwar, Ish Kumar Khanna, Raviraj Sukumar Pillai, Sivaram Pillarisetti
  • VARIANT ENDOGLUCANASES AND RELATED POLYNUCLEOTIDES
    Publication number: 20120009631
    Abstract: The invention provides variants of the Clostridium thermocellum endoglucanase (CeIG) that have improved endoglucanase activity compared to the wild type enzyme. Also provided are related polynucleotides, compositions, vectors, host cells, and methods of use.
    Type: Application
    Filed: March 10, 2010
    Publication date: January 12, 2012
    Applicant: CODEXIS, INC.
    Inventors: Jie Yang, Xiyun Zhang, Ish Kumar Dhawan, Andrew Shaw
  • Endoglucanases
    Patent number: 8088608
    Abstract: The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: January 3, 2012
    Assignee: Codexis, Inc.
    Inventors: Jie Yang, Andrew Shaw, Ish Kumar Dhawan, Onorato Campopiano, Kripa Rao
  • Biccyclic compounds as GATA modulators
    Patent number: 7989463
    Abstract: Novel bicyclic compounds of the formula (I), stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided. Additionally, methods of forming novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided: wherein R1, R2, m, and n are defined herein.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: August 2, 2011
    Assignee: Dr. Reddy's Laboratories Limited
    Inventors: Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti