Patents by Inventor Ish KUMAR

Ish KUMAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED RELEASE NIACIN FORMULATIONS
    Publication number: 20110123575
    Abstract: Modified release pharmaceutical formulations comprising niacin in a non-swellable core, and processes for preparation of the formulations.
    Type: Application
    Filed: June 2, 2009
    Publication date: May 26, 2011
    Applicants: DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
    Inventors: Rajesh Vooturi, Dhanajay Singare, Shantanu Yeshwant Damle, Pradeep Jairao Karatgi, Sesha Sai Marella, Harshal Prabhakar Bhagwatwar, Ish Kumar Khanna, Raviraj Sukumar Pillai
  • NOVEL BISMUTH(III) NSAID COMPOUNDS AND METHODS FOR THEIR USE
    Publication number: 20110086911
    Abstract: The present invention relates to the field of non-specific anti inflammatory drugs (NSAIDs). In particular, the invention relates to bismuth(III) tris-carboxylate complexes having the formula [Bi(III)L3]n including its pharmaceutically acceptable salts and solvates, wherein, L is chosen from the group comprising carboxylato-NSAIDs, their derivatives, prodrugs or metabolytes, and n is ?1. The bismuth(III) tris-carboxylate complexes of the invention may be formulated for use in treatments for a wide range of ailments, particularly those where an anti-microbial activity is advantageous. In a particularly preferred embodiment the bismuth(III) tris-carboxylate complexes of the present invention exhibit activity against bacteria found in the gastrointestinal tract such as Helicobacter pylori, Escherichia coli, Klebsiella pneumoniae, Bacillus pumilus, Staphylococcus aureus and Staphylococcus epidermidis.
    Type: Application
    Filed: October 13, 2009
    Publication date: April 14, 2011
    Applicant: Monash University
    Inventors: Philip Craig ANDREWS, Peter Courtney JUNK, Ish KUMAR, Richard L. FERRERO
  • COMBINATIONS OF NIACIN AND AN OXICAM
    Publication number: 20110086074
    Abstract: Pharmaceutical formulations comprising a combination of niacin and an oxicam NSAID, for oral administration, and methods of preparing the formulations.
    Type: Application
    Filed: June 2, 2009
    Publication date: April 14, 2011
    Applicants: DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
    Inventors: Pradeep Jairao Karatgi, Thilek Kumar Muniyappan, Shantanu Yeshwant Damle, Sesha Sai Marella, Harshal Prabhakar Bhagwatwar, Raviraj Sukumar Pillai, Ish Kumar Khanna
  • ENDOGLUCANASES
    Publication number: 20100267089
    Abstract: The present invention relates to variant endoglucanases and particularly endoglucanases having improved properties over wild-type endoglucanase.
    Type: Application
    Filed: March 31, 2010
    Publication date: October 21, 2010
    Applicant: CODEXIS, INC.
    Inventors: JIE YANG, ANDREW SHAW, ISH KUMAR DHAWAN, ONORATO CAMPOPIANO, KRIPA RAO
  • TRANSAMINASE POLYPEPTIDES
    Publication number: 20100209981
    Abstract: The present disclosure provides engineered transaminase enzymes having improved properties as compared to a naturally occurring wild-type transaminase enzyme. Also provided are polynucleotides encoding the engineered transaminase enzymes, host cells capable of expressing the engineered transaminase enzymes, and methods of using the engineered transaminase enzymes to synthesize a variety of chiral compounds.
    Type: Application
    Filed: January 8, 2010
    Publication date: August 19, 2010
    Applicant: CODEXIS, INC.
    Inventors: ISH KUMAR DHAWAN, GREGORY MILLER, XIYUN ZHANG
  • NOVEL HETEROCYCLIC COMPOUNDS AS GATA MODULATORS
    Publication number: 20100144722
    Abstract: Novel heterocyclic compounds, sstereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided. Additionally, methods of forming novel heterocyclic compounds, stereoisomers thereof and/or pharmaceutically acceptable salts of formula (I) and its stereoisomers are provided.
    Type: Application
    Filed: September 3, 2009
    Publication date: June 10, 2010
    Applicant: Dr. Reddy's Laboratories Ltd.
    Inventors: Christopher W. Alexander, Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti
  • Novel Biccyclic Compounds As GATA Modulators
    Publication number: 20100144731
    Abstract: Novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided. Additionally, methods of forming novel bicyclic compounds, stereoisomers, and/or pharmaceutically acceptable salts of the novel bicyclic compounds, and/or pharmaceutically acceptable salts of the stereoisomers of the novel bicyclic compounds are provided.
    Type: Application
    Filed: September 3, 2009
    Publication date: June 10, 2010
    Applicant: Dr. Reddy's Laboratories Ltd.
    Inventors: Dibyendu De, Ish Kumar Khanna, Sivaram Pillarisetti
  • Heteroarylakanoic acids as intergrin receptor antagonists
    Patent number: 7119098
    Abstract: The present invention relates to a class of compounds represented by formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of Formula (I), and methods of selectively antagonizing the ???3 and/or the ???5 integrin without significantly antagonizing the IIb/IIIa integrin.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: October 10, 2006
    Assignee: Pharmacia Corporation
    Inventors: Srinivasan Raj Nagarajan, Ish Kumar Khanna, Michael B. Tollefson, Scott B. Mohler, Barbara B. Chen, Mark Russell, Balekudru Devadas, Thomas D. Penning, Lori A. Schretzman, Dale P. Spangler, Mark L. Boys, Nizal S. Chandrakumar, Hwang-Fun Lu
  • Cycloalkyl alkanoic acids as integrin receptor antagonists
    Patent number: 6949578
    Abstract: The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the ?v?3 and/or ?v?5 integrin.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: September 27, 2005
    Assignee: Pharmacia Corporation
    Inventors: Ish Kumar Khanna, Michael Clare, Alan F. Gasiecki, Thomas Rogers, Barbara Chen, Mark Russell, Hwang-Fun Lu
  • Heteroarylalkanoic acids as integrin receptor antagonists
    Patent number: 6933304
    Abstract: The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively antagonizing the ?V?3 and/or the ?V?5 integrin without significantly antagonizing the IIb/IIIa or ?V?6 integrin.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: August 23, 2005
    Assignee: Pharmacia Corporation
    Inventors: Srinivasan Raj Nagarajan, Ish Kumar Khanna, Michael B. Tollefson, Scott B. Mohler, Barbara Chen, Mark Russell, Balekudru Devadas, Thomas D. Penning, Lori A. Schretzman, Dale P. Spangler, Mark Laurence Boys, Nizal Samuel Chandrakumar, Hung-Fun Lu
  • Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
    Patent number: 6921767
    Abstract: The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the ?v?3 and/or ?v?5 integrin.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: July 26, 2005
    Assignee: Pharmacia Corporation
    Inventors: Nagarajan R. Srinivasan, Ish Kumar Khanna, Michael Clare, Alan Gasiecki, Thomas Rogers, Barbara Chen, Mark Russell, Hwang-Fun Lu, Yu Yi, Renee M. Huff, Bipinchandra N. Desai, Balekudru Devadas, Mihir D. Parikh, Thomas Penning
  • Cycloalkyl alkanoic acids as integrin receptor antagonists
    Patent number: 6900232
    Abstract: The present invention relates to a class of compounds represented by the Formula I Wherein A1 is a pyridinyl of the formula optionally substituted by one or more Rk selected from the group consisting of hydroxy, alkyl, alkoxy, alkoxyalkyl, thioalkyl, haloalkyl, cyano, amino alkylamino, halogen, acylamino, sulfonamide and —COR; and R is hydroxy, alkoxy, alkyl or amino; and pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the ?v?3 and/or ?v?5 integrin.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: May 31, 2005
    Assignee: Pharmacia Corporation
    Inventors: Ish Kumar Khanna, Michael Clare, Alan F. Gasiecki, Thomas Rogers, Barbara Chen, Mark Russell, Hwang-Fun Lu
  • Cycloalkyl alkanoic acids as integrin receptor antagonists
    Publication number: 20040259869
    Abstract: The present invention relates to a class of compounds represented by the Formula I 1
    Type: Application
    Filed: July 14, 2004
    Publication date: December 23, 2004
    Inventors: Ish Kumar Khanna, Michael Clare, Alan F. Gasiecki, Thomas Rogers, Barbara Chen, Hwang-Fun Lu
  • Dihydrostilbene alkanoic acid derivatives
    Patent number: 6833366
    Abstract: The present invention relates to a class of compounds represented by the Formula 1. or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula 1, and methods of selectively inhibiting or antagonizing the &agr;v&bgr;3 and/or the &agr;v&bgr;5 integrin.
    Type: Grant
    Filed: September 9, 2003
    Date of Patent: December 21, 2004
    Assignee: Pharmacia Corporation
    Inventors: Thomas Rogers, Michael Clare, Hwang-Fun Lu, Mark Russell, James W. Malecha, Ish Kumar Khanna, Thomas Penning, Srinivasan Raj Nagarajan
  • Heteroarylakanoic acids as intergrin receptor antagonists
    Publication number: 20040092497
    Abstract: The present invention relates to a class of compounds represented by formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of Formula (I), and methods of selectively antagonizing the &agr;&ngr;&bgr;3 and/or the &agr;&ngr;&bgr;5 integrin without significantly antagonizing the IIb/IIIa integrin.
    Type: Application
    Filed: September 5, 2003
    Publication date: May 13, 2004
    Inventors: Srinivasan Raj Nagarajan, Ish Kumar Khanna, Michael B. Tollefson, Scott B, Mohler, Barbara B. Chen, Mark Russell, Balekudru Devadas, Thomas D. Penning, Lori A. Schretzman, Dale P. Spangler, Mark L. Boys, Nizal S. Chandrakumar, Hwang-Fun Lu
  • Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
    Publication number: 20040092538
    Abstract: The present invention relates to a class of compounds represented by the Formula I 1
    Type: Application
    Filed: December 20, 2002
    Publication date: May 13, 2004
    Inventors: Srinivasan R. Nagarajan, Ish Kumar Khanna, Michael Clare, Alan Gasiecki, Thomas Rogers, Barbara Chen, Mark Russell, Hwang-Fun Lu, Yu Yi, Renee M. Huff, Bipinchandra N. Desai, Balekudru Devadas, Mihir D. Parikh, Thomas Penning
  • Dihydrostilbene alkanoic acid derivatives
    Patent number: 6720315
    Abstract: The present invention relates to a class of compounds represented by the Formula 1. or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula 1, and methods of selectively inhibiting or antagonizing the &agr;V&bgr;3 and/or the &agr;V&bgr;5 integrin.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: April 13, 2004
    Assignee: Pharmacia Corporation
    Inventors: Thomas Rogers, Michael Clare, Hwang-Fun Lu, Mark Russell, James W. Malecha, Ish Kumar Khanna, Thomas Penning, Srinivasan Raj Nagarajan, Heather Stenmark
  • Compounds containing a bicyclic ring system useful as alpha v beta 3 antagonists
    Publication number: 20040058915
    Abstract: The present invention relates to a class of compounds represented by the Formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the &agr;v&bgr;3 and/or &agr;v&bgr;5 integrin. The ring A-B, is selected from the group consisting of the formula II all optionally substituted and bonded to X and Z1 at any position.
    Type: Application
    Filed: August 18, 2003
    Publication date: March 25, 2004
    Inventors: Ish Kumar Khanna, Yi Yu, Devadas Balekudra, Hwang-Fun Lu, Nizal S. Chandrakumar
  • Gem-substituted alpha v beta 3 antagonists
    Publication number: 20040043994
    Abstract: The present invention relates to a class of compounds represented by the Formula I.
    Type: Application
    Filed: January 21, 2003
    Publication date: March 4, 2004
    Inventors: Ish Kumar Khanna, Yi Yu, Hwang-Fun Lu, Nizal S. Chandrakumar, Renee M. Huff, Mark Russell, Mark L. Boys, Lori A. Schretzman, Barbara B. Chen, Bipinchandra N. Desai, Srinivasan Raj Nagarajan, Alan F. Gasiecki, Thomas D. Penning, Thomas Rogers, John Adam Wendt, Albert Khilevich, Yaping Wang
  • Gem-substituted &agr;v&bgr;3 antagonists
    Patent number: 6531494
    Abstract: The present invention relates to a class of compounds represented by the Formula I. or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the &agr;V&bgr;3 and/or the &agr;V&bgr;5 integrin.
    Type: Grant
    Filed: August 29, 2001
    Date of Patent: March 11, 2003
    Assignee: Pharmacia Corporation
    Inventors: Ish Kumar Khanna, Yi Yu, Balekudru Devadas, Hwang-Fun Lu, Nizal S Chandrakumar, Renee M. Huff, Bipinchandra N. Desai, Srinivasan Raj Nagarajan, Alan F. Gasiecki, Thomas D. Penning, Mark A. Russell, Mark L. Boys, Lori A. Schretzman, Barbara B. Chen, Thomas Rogers, John Adam Wendt, Albert Khilevich, Yaping Wang