Patents by Inventor Issam Raad
Issam Raad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11896739Abstract: Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.Type: GrantFiled: March 1, 2021Date of Patent: February 13, 2024Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad, Andrew P. Dennis
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Publication number: 20230405191Abstract: Antimicrobial catheters and medical devices are provided. In some aspects, a low durometer aliphatic polyether polyurethane may be impregnated with a first antimicrobial agent (e.g., minocycline and rifampin) and coated with a second antimicrobial agent (e.g., chlorhexidine, gendine, or gardine). The antimicrobial catheters may display improved flexibility and resistance to kinking. Methods of producing the antimicrobial catheters are also provided.Type: ApplicationFiled: August 25, 2023Publication date: December 21, 2023Applicant: Board of Regents, The University of Texas SystemInventors: Joel ROSENBLATT, Issam RAAD
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Patent number: 11826332Abstract: In some aspects, provided herein are antimicrobial compositions comprising partially esterified polygalacturonic acid and certain fatty acids (e.g., caprylic acid). In some embodiments, the antimicrobial composition may be administered (e.g., topically or orally) to a subject, such as a human patient to treat an infection (e.g., an infection comprising a biofilm). In some aspects, improved catheters are provided.Type: GrantFiled: June 28, 2021Date of Patent: November 28, 2023Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad
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Patent number: 11738119Abstract: Antimicrobial catheters and medical devices are provided. In some aspects, a low durometer aliphatic polyether polyurethane may be impregnated with a first antimicrobial agent (e.g., minocycline and rifampin) and coated with a second antimicrobial agent (e.g., chlorhexidine, gendine, or gardine). The antimicrobial catheters may display improved flexibility and resistance to kinking. Methods of producing the antimicrobial catheters are also provided.Type: GrantFiled: July 8, 2020Date of Patent: August 29, 2023Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad
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Publication number: 20220087963Abstract: In some aspects, provided herein are antimicrobial compositions comprising partially esterified polygalacturonic acid and certain fatty acids (e.g., caprylic acid). In some embodiments, the antimicrobial composition may be administered (e.g., topically or orally) to a subject, such as a human patient to treat an infection (e.g., an infection comprising a biofilm). In some aspects, improved catheters are provided.Type: ApplicationFiled: June 28, 2021Publication date: March 24, 2022Applicant: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad
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Patent number: 11065223Abstract: In some aspects, provided herein are antimicrobial compositions comprising partially esterified polygalacturonic acid and certain fatty acids (e.g., caprylic acid). In some embodiments, the antimicrobial composition may be administered (e.g., topically or orally) to a subject, such as a human patient to treat an infection (e.g., an infection comprising a biofilm). In some aspects, improved catheters are provided.Type: GrantFiled: February 21, 2017Date of Patent: July 20, 2021Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad
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Publication number: 20210178023Abstract: Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.Type: ApplicationFiled: March 1, 2021Publication date: June 17, 2021Applicant: Board of Regents, The University of Texas SystemInventors: Joel ROSENBLATT, Issam RAAD, Andrew P. DENNIS
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Patent number: 10953137Abstract: Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.Type: GrantFiled: August 26, 2019Date of Patent: March 23, 2021Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad, Andrew P. Dennis
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Publication number: 20210060213Abstract: Antimicrobial catheters and medical devices are provided. In some aspects, a low durometer aliphatic polyether polyurethane may be impregnated with a first antimicrobial agent (e.g., minocycline and rifampin) and coated with a second antimicrobial agent (e.g., chlorhexidine, gendine, or gardine). The antimicrobial catheters may display improved flexibility and resistance to kinking. Methods of producing the antimicrobial catheters are also provided.Type: ApplicationFiled: July 8, 2020Publication date: March 4, 2021Applicant: Board of Regents, The University of Texas SystemInventors: Joel ROSENBLATT, Issam RAAD
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Patent number: 10744232Abstract: Antimicrobial catheters and medical devices are provided. In some aspects, a low durometer aliphatic polyether polyurethane may be impregnated with a first antimicrobial agent (e.g., minocycline and rifampin) and coated with a second antimicrobial agent (e.g., chlorhexidine, gendine, or gardine). The antimicrobial catheters may display improved flexibility and resistance to kinking. Methods of producing the antimicrobial catheters are also provided.Type: GrantFiled: April 17, 2014Date of Patent: August 18, 2020Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad
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Patent number: 10589003Abstract: Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.Type: GrantFiled: March 14, 2018Date of Patent: March 17, 2020Assignee: The Board of Regents of the University of Texas SystemInventor: Issam Raad
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Publication number: 20190388591Abstract: Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.Type: ApplicationFiled: August 26, 2019Publication date: December 26, 2019Applicant: Board of Regents, The University of Texas SystemInventors: Joel ROSENBLATT, Issam RAAD, Andrew P. DENNIS
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Patent number: 10434221Abstract: Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.Type: GrantFiled: November 21, 2017Date of Patent: October 8, 2019Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad, Andrew P. Dennis
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Publication number: 20190046488Abstract: In some aspects, provided herein are antimicrobial compositions comprising partially esterified polygalacturonic acid and certain fatty acids (e.g., caprylic acid). In some embodiments, the antimicrobial composition may be administered (e.g., topically or orally) to a subject, such as a human patient to treat an infection (e.g., an infection comprising a biofilm). In some aspects, improved catheters are provided.Type: ApplicationFiled: February 21, 2017Publication date: February 14, 2019Applicant: Board of Regents, The University of Texas SystemInventors: Joel ROSENBLATT, Issam RAAD
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Publication number: 20180303977Abstract: Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.Type: ApplicationFiled: March 14, 2018Publication date: October 25, 2018Applicant: The Board of Regents of the University of Texas SystemInventor: Issam RAAD
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Patent number: 10086114Abstract: Provided are antimicrobial solutions, including catheter lock solutions. In some embodiments, the solution contains an antibiotic (e.g., minocycline or trimethoprim), EDTA, and an alcohol (e.g., ethanol), wherein the pH of the solution is adjusted to about 6-8 to reduce precipitation. Methods of using the solutions and kits are also provided.Type: GrantFiled: November 4, 2016Date of Patent: October 2, 2018Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad
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Publication number: 20180093018Abstract: Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.Type: ApplicationFiled: November 21, 2017Publication date: April 5, 2018Applicant: Board of Regents, The University of Texas SystemInventors: Joel ROSENBLATT, Issam RAAD, Andrew P. DENNIS
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Patent number: 9913820Abstract: Provided are antimicrobial solutions comprising a glyceryl nitrate (e.g., glyeryl trinitrate) in combination with a chelator (e.g., citrate), a peroxide, a fatty acid, and/or an alcohol (e.g., ethanol). In various aspects these components may synergistically act to kill or reduce the growth of microbes, such as bacteria or fungi, present in a biofilm.Type: GrantFiled: September 8, 2016Date of Patent: March 13, 2018Assignee: Board of Regents, The University of Texas SystemsInventors: Issam Raad, Joel Rosenblatt
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Patent number: 9849217Abstract: Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.Type: GrantFiled: April 17, 2014Date of Patent: December 26, 2017Assignee: Board of Regents, The University of Texas SystemInventors: Joel Rosenblatt, Issam Raad, Andrew P. Dennis
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Publication number: 20170151373Abstract: Provided are antimicrobial solutions, including catheter lock solutions. In some embodiments, the solution contains an antibiotic (e.g., minocycline or trimethoprim), EDTA, and an alcohol (e.g., ethanol), wherein the pH of the solution is adjusted to about 6-8 to reduce precipitation. Methods of using the solutions and kits are also provided.Type: ApplicationFiled: November 4, 2016Publication date: June 1, 2017Inventors: Joel ROSENBLATT, Issam RAAD