Patents by Inventor Issam Raad
Issam Raad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9565857Abstract: The present invention provides antimicrobial solutions that in certain cases comprise a biguanide and a glycol ether and, in some cases, optionally also includes combinations of at least one an alcohol, at least one chelator, glycerol, deoxycholate, and/or at least one alkylpolyglucoside. In certain aspects the invention comprises a biguanide and deoxycholate or a combination of chelator, ethanol, and alkylpolyglucoside. Also provided are methods for rapidly killing and/or reducing bacteria, fungi, or virus from surfaces, for example, including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as medical equipment, pipelines etc.Type: GrantFiled: September 9, 2011Date of Patent: February 14, 2017Assignee: Board of Regents, The University of Texas SystemInventors: Issam Raad, George Abiaad
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Publication number: 20160374978Abstract: Provided are antimicrobial solutions comprising a glyceryl nitrate (e.g., glyeryl trinitrate) in combination with a chelator (e.g., citrate), a peroxide, a fatty acid, and/or an alcohol (e.g., ethanol). In various aspects these components may synergistically act to kill or reduce the growth of microbes, such as bacteria or fungi, present in a biofilm.Type: ApplicationFiled: September 8, 2016Publication date: December 29, 2016Applicant: Board of Regents, The University of Texas SystemInventors: Issam RAAD, Joel ROSENBLATT
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Patent number: 9457002Abstract: Provided are antimicrobial solutions comprising a glyceryl nitrate (e.g., glyeryl trinitrate) in combination with a chelator (e.g., citrate), a peroxide, a fatty acid, and/or an alcohol (e.g., ethanol). In various aspects these components may synergistically act to kill or reduce the growth of microbes, such as bacteria or fungi, present in a biofilm.Type: GrantFiled: August 8, 2013Date of Patent: October 4, 2016Assignee: Board of Regents, The University of Texas SystemInventors: Issam Raad, Joel Rosenblatt
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Publication number: 20160074560Abstract: Antimicrobial catheters and medical devices are provided. In some aspects, a low durometer aliphatic polyether polyurethane may be impregnated with a first antimicrobial agent (e.g., minocycline and rifampin) and coated with a second antimicrobial agent (e.g., chlorhexidine, gendine, or gardine). The antimicrobial catheters may display improved flexibility and resistance to kinking. Methods of producing the antimicrobial catheters are also provided.Type: ApplicationFiled: April 17, 2014Publication date: March 17, 2016Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Joel ROSENBLATT, Issam RAAD
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Publication number: 20160074559Abstract: Biodegradable antimicrobial films are provided that are solid at room temperature and substantially liquefy in situ after implantation into a mammal, such as a human patient. Methods of using the films to cover a medical device, such as a breast implant, prior to insertion into a subject are also provided.Type: ApplicationFiled: April 17, 2014Publication date: March 17, 2016Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Joel ROSENBLATT, Issam RAAD, Andrew P. DENNIS
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Publication number: 20150359945Abstract: Provided are polymer-based surfaces (e.g., gloves) with an antimicrobial coating, e.g., comprising chlorhexidine and a partially hydrolyzed polyvinyl acetate copolymer, or a biguanide and a silicone. Methods of coating polymer-based surfaces with antimicrobial compositions are also provided.Type: ApplicationFiled: January 9, 2014Publication date: December 17, 2015Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Joel ROSENBLATT, Issam RAAD
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Publication number: 20150196523Abstract: Provided are antimicrobial solutions comprising a glyceryl nitrate (e.g., glyeryl trinitrate) in combination with a chelator (e.g., citrate), a peroxide, a fatty acid, and/or an alcohol (e.g., ethanol). In various aspects these components may synergistically act to kill or reduce the growth of microbes, such as bacteria or fungi, present in a biofilm.Type: ApplicationFiled: August 8, 2013Publication date: July 16, 2015Applicant: Board of Regents, The University of Texas SystemInventors: Issam Raad, Joel Rosenblatt
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Patent number: 9078441Abstract: The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as hospital equipment, pipelines etc.Type: GrantFiled: April 15, 2014Date of Patent: July 14, 2015Assignee: Board of Regents, The University of Texas SystemInventor: Issam Raad
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Publication number: 20140228327Abstract: The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as hospital equipment, pipelines etc.Type: ApplicationFiled: April 15, 2014Publication date: August 14, 2014Applicant: Board of Regents, The University of Texas SystemInventor: Issam RAAD
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Patent number: 8709342Abstract: The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as hospital equipment, pipelines etc.Type: GrantFiled: September 17, 2012Date of Patent: April 29, 2014Assignee: Board of Regents, The University of Texas SystemInventor: Issam Raad
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Publication number: 20130231302Abstract: The present invention provides antimicrobial solutions that in certain cases comprise a biguanide and a glycol ether and, in some cases, optionally also includes combinations of at least one an alcohol, at least one chelator, glycerol, deoxycholate, and/or at least one alkylpolyglucoside. In certain aspects the invention comprises a biguanide and deoxycholate or a combination of chelator, ethanol, and alkylpolyglucoside. Also provided are methods for rapidly killing and/or reducing bacteria, fungi, or virus from surfaces, for example, including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as medical equipment, pipelines etc.Type: ApplicationFiled: September 9, 2011Publication date: September 5, 2013Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Issam Raad, George Abiaad
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Publication number: 20130164363Abstract: The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as hospital equipment, pipelines etc.Type: ApplicationFiled: September 17, 2012Publication date: June 27, 2013Applicant: Board of Regents, The University of Texas SystemInventor: Issam RAAD
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Patent number: 8426044Abstract: A method for imparting broad spectrum antimicrobial activity to a medical device. The medical device is sequentially contacted with a first antimicrobial component, such as an antiseptic, and thereafter with a second antimicrobial component, such as a mixture of antibiotics. The first component may be a guanidium compound, such as chlorhexidine. The second component may be a mixture of a tetracycline, such as minocycline, and a rifamycin, such as rifampin.Type: GrantFiled: March 18, 2010Date of Patent: April 23, 2013Assignee: Board of Regents, The University of Texas SystemInventor: Issam Raad
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Publication number: 20120064372Abstract: A method for imparting broad spectrum antimicrobial activity to a medical device. The medical device is sequentially contacted with a first antimicrobial component, such as an antiseptic, and thereafter with a second antimicrobial component, such as a mixture of antibiotics. The first component may be a guanidium compound, such as chlorhexidine. The second component may be a mixture of a tetracycline, such as minocycline, and a rifamycin, such as rifampin.Type: ApplicationFiled: March 18, 2010Publication date: March 15, 2012Applicant: The Board of Regents of the University of Texas SystemInventor: Issam Raad
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Publication number: 20110201692Abstract: The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as hospital equipment, pipelines etc.Type: ApplicationFiled: April 27, 2011Publication date: August 18, 2011Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventor: Issam Raad
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Patent number: 7713472Abstract: The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially in-dwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.Type: GrantFiled: January 11, 2002Date of Patent: May 11, 2010Assignee: Board of Regents, The University of Texas SystemInventors: Issam Raad, Hend A. Hanna, Nabeel Nabulsi
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Publication number: 20100055086Abstract: The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as hospital equipment, pipelines etc.Type: ApplicationFiled: September 15, 2009Publication date: March 4, 2010Inventor: Issam Raad
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Patent number: 7651661Abstract: The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially indwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.Type: GrantFiled: October 19, 2007Date of Patent: January 26, 2010Assignee: Board of Regents, the University of Texas SystemInventors: Issam Raad, Hend A. Hanna, Nabeel Nabulsi
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Patent number: 7601731Abstract: The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as hospital equipment, pipelines etc.Type: GrantFiled: June 7, 2004Date of Patent: October 13, 2009Assignee: Board of Regents, the University of Texas SystemInventor: Issam Raad
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Publication number: 20080183152Abstract: The present invention provides novel broad spectrum antiseptic compounds that further have properties that allow them to be coated/impregnated into polymer surfaces. Methods for coating these antiseptic compounds onto medical devices especially indwelling medical devices to prevent the growth of pathogens in such devices and hence, to prevent infection to patients via such devices are provided. The invention also provides antiseptics that are useful as general surface disinfectants and sterilizers, fluid disinfectants and biocide preservatives.Type: ApplicationFiled: October 19, 2007Publication date: July 31, 2008Inventors: Issam Raad, Hend A. Hanna, Nabeel Nabulsi