Abstract: The present invention provides a process for the manufacture of GLP-1 analogues with high yield and purity by fragment condensation on the solid phase. In particular, it describes a convergent synthesis by condensation of a C-terminal pseudoproline fragment A with a fragment B bound to a solid support, followed by deprotection and cleavage from the support and final purification to yield the desired peptide. The invention further provides intermediates useful in the manufacturing process.

Abstract: A material for separating and pumping oxygen is disclosed. The material is a zeolite doped with a chemical element having an electron density of between 30 kJ/mol and 150 kJ/mol. The material is configured for controllable oxygen desorption between 150° C. and 300° C. and pumping the released oxygen into an area having an ambient pressure of less than 100 pascals.

Abstract: This document describes techniques for fine-motion virtual-reality or augmented-reality control using radar. These techniques enable small motions and displacements to be tracked, even in the millimeter or sub-millimeter scale, for user control actions even when those actions are small, fast, or obscured due to darkness or varying light. Further, these techniques enable fine resolution and real-time control, unlike conventional RF-tracking or optical-tracking techniques.

Abstract: An innovative plant (10) for the production with the “spun bonding” technology or similar of a web (V) of non-woven fabric, comprising: a melting station (11) suitable for receiving and melting a polymeric base material (MR), an extrusion bar or head (12) with a plurality of extrusion or drawing nozzles (12a) adapted to receive from the melting station (11) the polymeric material (MR) in the molten state to produce a plurality or bundle of continuous filaments (FF); a conveyor belt (13) adapted to advance along a direction of advancement (A) and to receive from the above the continuous filaments (F), produced by the extrusion nozzles (12a), so as to form a web (V) of non-woven fabric; and consolidation means (14) designed to consolidate the non-woven web (V) formed on the conveyor belt (13); wherein the plant (10) is characterized by a special structure (20) comprising a base platform (21), rotatable (f, f?, f?) around a respective vertical rotation axis (X), and wherein the melting station (11), suitable for

Abstract: The present invention relates to antibodies, and fragments thereof, that bind and inhibit CD73. The invention also relates to cells producing such compounds; methods of making such compounds, and antibodies, fragments, variants, and derivatives thereof; pharmaceutical compositions comprising the same; methods of using the compounds to diagnose, treat or prevent diseases, e.g., cancer.

Abstract: An optoelectronic multiscopic image display and/or capture device, including a support, an array of optoelectronic circuits resting on the support, and lenses covering the optoelectronic circuits. Each optoelectronic circuit includes a number N of photosensors capable of capturing a pixel or pixels of an image of a scene according to different viewpoints and/or number N of display circuits capable of displaying a pixel or pixels of an image of a scene according to the different viewpoints, N being a natural number greater than or equal to 3.

Abstract: The invention relates to a system for displaying information to a user, comprising: an emission device arranged to emit light so as to display information to a user, the emission device being adapted to emit the light in a pulsed manner so that the intensity of the light varies between a high value and a low value, a selective viewing device comprising a panel, the panel being adapted so that the user can view the light which is emitted by the emission device through that panel so as to visually perceive the information being displayed, the panel having a variable transparency which can be varied between a state of high transparency and a state of low transparency, the system being adapted to synchronize the emission device and the selective viewing device so that the states of the emission device emitting light at a high-intensity value and the states of the panel of the selective viewing device of high transparency overlap in time, the emission device being adapted so that the light is emitted in a pulsed m

Abstract: A method, system and/or computer usable program product for managing automated guidance and validation of stacking items including generating a predicted map of an item set stacked onto a handling unit; generating an observed map of the item set stacked onto the handling unit; and comparing the predicted map with the observed map to verify the position and orientation of the item set stacked onto the handling unit.

Abstract: A system for powering a network element of a fiber optic wide area network is disclosed. When communication data is transferred between a central office (CO) and a subscriber terminal using a network element to convert optical to electrical (O-E) and electrical to optical (E-O) signals between a fiber from the central office and twisted wire pair, coaxial cable or Ethernet cable transmission lines from the subscriber terminal, techniques related to local powering of a network element or drop site by the subscriber terminal or subscriber premise remote powering device are provided. Certain advantages and/or benefits are achieved using the present invention, such as freedom from any requirement for additional meter installations or meter connection charges and does not require a separate power network.

Abstract: A distributed computing device generates a gradient descent matrix based on data received by the distributed computing device and a model stored on the distributed computing device. The distributed computing device calculates a sampled gradient descent matrix based on the gradient descent matrix and a random matrix. The distributed computing device iteratively executes a process to determine a consensus gradient descent matrix in conjunction with a plurality of additional distributed computing devices connected by a network to the distributed computing device. The consensus gradient descent matrix is based on the sampled gradient descent matrix and a plurality of additional sampled gradient decent matrices calculated by the plurality of additional distributed computing devices. The distributed computing device updates the model stored on the distributed computing device based on the consensus gradient descent matrix.

Abstract: A band-switching network includes a dual-band balun and a switch network. The dual-band balun includes a first output and a second output. The switch network includes a first switch and a second switch in which an input to the first switch is coupled to the first output and an input to the second switch is coupled to the second balanced output. The dual-band balun further includes a primary coil, a first secondary coil and a second secondary coil in which the first secondary coil is coupled to the first balanced output and the second secondary coil is coupled to the second balanced output. In one embodiment, the primary coil and the first secondary coil are coupled by a first coupling factor k1, and the primary coil and the second secondary coil are coupled by a second coupling factor k2 that is different from the first coupling factor k1.

Abstract: A method of manufacturing a wind turbine blade shell part is described. Fibre mats and a root end insert are laid up in a mould part in a layup procedure by use of an automated layup system. The fibre mats are laid up by use of a buffer so that the fibre mats may continuously be laid up on the mould surface, also during a cutting procedure. The root end insert is prepared in advance and mounted on a mounting plate. The root end insert is lowered onto the mould by use of the mounting plate and a lowering mechanism. After the wind turbine blade shell has been moulded, the mounting plate is removed.

Abstract: A method of operating a magnetic resonance imaging system (10) with regard to acquiring multiple-phase dynamic contrast-enhanced magnetic resonance images, the method comprising steps of acquiring (48) a first set of magnetic resonance image data (xpre) prior to administering a contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (52) a first image of the spatial distribution of fat (Ipre) of at least the portion of the subject of interest (20), acquiring (50) at least a second set of magnetic resonance image data (x2) of at least the portion of the subject of interest (20) after administering the contrast agent to the subject of interest (20), by employing a water/fat magnetic resonance signal separation technique, determining (54) at least a second image of the spatial distribution of fat (I2ph) of at least the portion of the subject of interest (20), applying (56) an image registration method to the second image of the spatial

Abstract: Methods and systems related to speculative resource allocation for routing on an interconnect fabric are disclosed herein. One disclosed method includes speculatively allocating a collection of resources to support a set of paths through an interconnect fabric. The method also includes aggregating a set of responses from the set of paths at a branch node on the set of paths. If a resource contention is detected, the set of responses will include an indicator of a resource contention. The method will then further include transmitting, from the branch node and in response to the indicator of the resource contention, a deallocate message downstream and the indicator of the resource contention upstream, and reallocating resources for the multicast after a hold period.

Abstract: A package which comprises at least one electronic chip, an encapsulant encapsulating at least part of the at least one electronic chip, and a shielding layer on at least part of an external surface of the encapsulant configured for shielding an interior of the package with regard to cooling fluid for removing thermal energy from the at least one electronic chip.

Abstract: Described are circuits and techniques to increase the efficiency of radio-frequency (rf) amplifiers including rf power amplifiers (PAs) through “supply modulation” (also referred to as “drain modulation” or “collector modulation”), in which supply voltages provided to rf amplifiers is adjusted dynamically (“modulated”) overtime depending upon the rf signal being synthesized. For the largest efficiency improvements, a supply voltage can be adjusted among discrete voltage levels or continuously on a short time scale. The supply voltages (or voltage levels) provided to an rf amplifier may also be adapted to accommodate longer-term changes in desired rf envelope such as associated with adapting transmitter output strength to minimize errors in data transfer, for rf “traffic” variations.

Abstract: A system and method for mounting a Closed-Mouth Power Tong on a Well Servicing Rig in order is disclosed. The power tong can be operated remotely when making up or breaking out connections on oilfield tubing. The system utilizes an assembly that can lift and lower the tong to the appropriate height as required to engage the threads on the tubing. The assembly is connected to the blowout preventer or wellhead with a quick connect system that is adjustable for various angles so that the tong can be utilized in various positions to run tubing into, or out from, the well center unhindered.

Abstract: Systems and methods for occupant and guest interaction with a virtual environment are provided. Disclosed systems and methods enable occupants to create an event associated with a particular location in an area within a virtual environment. Graphical interfaces and display methods can display interactive event markers overlaying images of the area within the virtual environment.

Abstract: The subject matter of this specification can be implemented in, among other things, a method that includes storing translator linguistic resources for a personal account and project linguistic resources for a corporate account. The method includes creating a private profile for the personal account in response to the personal account being added to a team for the corporate account or being assigned to a translation project for the corporate account. A graphical user interface provides access to the translator linguistic resources within the translation project for the private profile without providing access to the translator linguistic resources within the translation project for the corporate account. The graphical user interface provides translation suggestions from the project linguistic resources within the translation project for the private profile without providing full access to the project linguistic resources within the translation project for the private profile.

Abstract: The present disclosure provides for a skate sharpening system comprising an operative unit and a base, the operative unit comprising a central body, the central body comprising a skate receiving slot, a skate clamp being positioned adjacent to the skate receiving slot such that a skate can be secured within the skate receiving slot for a sharpening operation, the operative unit further comprising a grinding unit, the grinding unit being configured to translate along a length of the slot such that the grinding unit can conduct the sharpening operation on the skate that is secured within the skate receiving slot, the operative unit being positioned over at least a portion of the base, the base comprising a swarf-receiving cavity, the operative unit and the base being pivotably connected.