Abstract: Integrated chips include first lines, formed on an underlying substrate. Spacers are formed conformally on sidewalls of the plurality of lines. Etch stop remnants are positioned on the sidewalls of the plurality of lines, between the spacers and the underlying substrate. Second lines are formed on the underlying substrate, between respective pairs of adjacent first lines.

Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.

Abstract: Roofing panels with water shedding features may be installed on the roof of a house or other structure in lieu of or as an underlayment for traditional roofing materials. The water shedding features can be built into a base of the roofing panels, as part of a frame for the roofing panels, or formed as part of a waterproofing layer applied to the base of the roofing panels, or which can be configured as a roofing panel. The roofing panels also can be installed in overlapping courses along a roof with water shedding features applied thereto or incorporated along one or more peripheral edges. The water shedding features of adjacent roofing panels will collect and divert water away from the upper surfaces and/or away from headlap and/or sidelap joints defined between the roofing panels.

Abstract: A method to achieve variable properties of a component using a coating free press hardened steel comprises: transferring a blank of a coating free press hardened steel (CFPHS) material having base blank properties into a heating unit having multiple induction heating coils; heating the blank within the heating unit to create a modified blank having differing modified blank properties throughout the modified blank compared to base blank properties; moving the modified blank out of the heating unit into a die; and forming a shaped part by operation of the die creating a finished CFPHS part.

Abstract: Systems and methods are disclosed that allow for providing targeted asset/advertisements for broadcast-wide programming feeds. The systems and methods allow network platforms to select among asset options provided with a content stream and/or replace assets in the content stream. In one arrangement, after selecting an asset, the asset is inserted into the content stream and the content stream is disseminated to subsequent network platforms (e.g., local platforms). At this time, the local platforms may insert local assets into the content stream in predetermined local asset insertion spots.

Abstract: A vehicle chock device includes a first body portion and a stepped-box body integrally formed with the first body portion. The stepped-box body has a lower portion and an upper portion. The stepped-box body transitions from a first generally planar, generally horizontal surface on the lower portion to an intermediate sloped surface to a generally planar, generally vertical surface on the upper portion. The lower portion has a second generally planar, generally horizontal surface configured to engage a supporting surface of a carrier vehicle on which an automobile is disposed. An opposite side of the upper portion that is opposite the generally planar, generally vertical surface defines a tire-contacting surface that is positioned to engage a vehicle tire of the automobile while the second generally planar, generally horizontal surface engages the supporting surface of the carrier vehicle.

Abstract: In some embodiments, methods of inhibiting, ameliorating, reducing the severity of, treating, reducing the likelihood of, or preventing social isolation stress or symptoms thereof in a subject in need thereof are described. In some embodiments, methods of determining a risk of social isolation stress in a subject are described.

Abstract: A tool, such as a tape measure, including a spring-based retraction system is shown. Various spring-based retraction system embodiments are configured to decrease the size occupied by the spring within the tape measure housing, which consequently reduces tape measure housing size providing a more compact tape measure. Various spring-based retraction system embodiments are configured to control retraction of the tape measure in a manner that reduces whip or otherwise controls tape blade retraction. Some retraction system embodiments utilize a reduction gear train, and others utilize a compression spring and a transmission system that converts rotational movement of the tape reel to axial movement, which compresses the spring.

Abstract: A method of picking a predetermined number of fasteners is provided. The method includes placing a fastener handling tool adjacent the predetermined number of fasteners. The fastener handling tool includes a body that includes a holding side, a picking side opposite the holding side, a front wall, a rear wall opposite the front wall and opposite side walls that extend between the holding side and the picking side. The body includes an elongated slot on the picking side that extends between the opposite side walls along a width of the body and an elongated hole on the picking side that is offset from the elongated slot. The elongated slot and the elongated hole extend parallel between the opposite sidewalls providing a gap between the elongated slot and the elongated hole. A magnet is located at the elongated hole. The predetermined number of fasteners are attracted to an edge of the elongated slot using the magnet located at the elongated hole.

Abstract: Crystalline forms of Compound I: pharmaceutically acceptable salts thereof, and solvates and hydrates thereof are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

Abstract: An atomic level deposition for mass functionalization of a cavity filled with a pathogen sensitive antibody reagent to functionalize each biosensor using atomic level vapor phase deposition enables high volume production of this sensor technology. A biosensor has a first substrate and a second substrate with a cavity formed in the first substrate to form a membrane. Holes are formed through the second substrate. An aluminum oxide layer is formed over the cavity and into the holes to form cores. The cavity is filled with a pathogen sensitive antibody reagent. A biofluid sample with the pathogen is deposited over the membrane. The biofluid is drawn through the cores to mix with the antibody reagent. The antibodies combine with the pathogen to change the impedance along the current path. The presence of the pathogen changes the ionic current flow through the biosensor for a positive detection of the pathogen.

Abstract: An electric drive system includes a power electronics module (PEM) having a DC-link capacitor and an inverter. A controller reduces power output of the inverter while a sensed temperature of an inverter power switch, a sensed current of the PEM, such as a sensed ripple current of the DC-link capacitor, and parameter values of the DC-link capacitor are indicative of a predicted temperature of the capacitor being greater than a threshold to maintain capacitor temperature lower than the threshold. The parameter values are obtainable from a thermal model of the DC-link capacitor. The thermal model may be derived from testing a test version of the PEM under different drive cycles in which for each drive cycle a set of information is recorded including a sensed temperature of the inverter power switch test version, a current of the PEM test version, and a sensed temperature of the DC-link capacitor test version.

Abstract: Methods, apparatus, and systems to non-invasively determine intra-luminal placement and patency of a vascular access device. Patency and/or placement are estimated indirectly by measuring a physiological parameter which is indicative of proper patency and/or placement of the vascular access device in a patient. The measurement is compared to a reference value or calibration. If the comparison indicates indication of proper patency and/or placement, a signal is generated. The signal can be used in a number of ways. One example is to give a user-perceivable alarm or indication of proper patency and/or placement. Non-limiting examples include activating a light, an audible buzzer, a vibration, readable displayed text or graphics, or some combination of the same. The user can then have an indirect and at least semi-automatic way of estimating proper patency and/or placement of a vascular access device.

Abstract: A system may include at least one processor configured to: obtain data of an aircraft, the data including and/or associated a flight path vector (FPV) and/or a flight path predictor (FPP); obtain image sensor data output; identify features associated with a runway; determine that the identified features are indicative of the runway; determine a touch down zone on the runway; determine whether the FPV and/or the FPP is in the touch down zone when the aircraft is at a decision altitude and/or is predicted to be in the touch down zone when the aircraft will be at the decision altitude; and (i) output a notification to proceed with a landing procedure, (ii) perform an operation configured to cause the aircraft to proceed with the landing procedure, (iii) output a notification to perform a go-around procedure, and/or (iv) perform an operation configured to cause the aircraft to perform the go-around procedure.

Abstract: A rocker panel for use in a vehicle, the rocker panel includes an outboard plate, an inboard plate, and a reinforcement structure. The reinforcement structure is disposed between the inboard plate and the outboard plate. The reinforcement structure includes one or more discrete steel tubes extending longitudinally between the outboard plate and the inboard plate.

Abstract: A voice-controlled electronic device that includes a device housing having a longitudinal axis bisecting opposing top and bottom surfaces and a side surface extending between the top and bottom surfaces. The device can further include one or more microphones disposed within the device housing and distributed radially around the longitudinal axis; a processor configured to execute computer instructions stored in a computer-readable memory for interacting with a user and processing voice commands received by the one or more microphones and first transducer and second transducers configured to generate sound waves within different frequency ranges.

Abstract: Assets of broadcast network content are targeted to network users of interest based on location information regarding user equipment devices. Asset providers can specify location targeting criteria via a graphical user interface displaying mapping information. This location targeting criteria can then be compared to location information regarding user equipment devices so that assets are delivered to appropriate devices. The comparison of the location targeting criteria to the device location information can be performed at the user equipment devices or at another location. In the latter case, the assets can be addressed to appropriate user equipment devices or appropriate user equipment devices can be directed to select the asset, which is broadcast via the network. In this manner, assets can be targeted to individual network users on a basis independent of network topology.

Abstract: The Internet can be configured to provide communications to a large number of Internet-of-Things (IoT) devices. Devices can be designed to address the need for network layers, from central servers, through gateways, down to edge devices, to grow unhindered, to discover and make accessible connected resources, and to support the ability to hide and compartmentalize connected resources. Network protocols can be part of the fabric supporting human accessible services that operate regardless of location, time, or space. Innovations can include service delivery and associated infrastructure, such as hardware and software. Services may be provided in accordance with specified Quality of Service (QoS) terms. The use of IoT devices and networks can be included in a heterogeneous network of connectivity including wired and wireless technologies.

Abstract: According to one embodiment, a flood vent panel includes a plurality of insulation pieces positioned together, and a panel frame surrounding the plurality of insulation pieces. The flood vent panel is configured to be coupled to a frame positionable on a structure, so as to at least partially block a fluid passageway through an opening in the structure. Each of the plurality of insulation pieces is separate from the other insulation pieces of the plurality of insulation pieces. Each of the plurality of insulation pieces is separate from the panel frame.

Abstract: One or more techniques and/or systems are disclosed for automatically adjusting conditioning rollers of a crimping implement, such as those used to condition hay or other crimped crops, such as cover crops. Adjustments can be made on the fly to rollers, crimpers, or down pressure applicators used to condition the crop based on several factors such as the condition of the crop, the type of crop, and more. Sensors can be used to detect the crops and others' conditions before and after conditioning, and automatic adjustments can be made, such as the distance between conditioning rollers, and/or the pressure applied by the rollers, etc. to meet a desired crop condition for the crimped crop.