Abstract: A tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Abstract: An tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Abstract: An tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Abstract: An tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Abstract: An tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Abstract: An tissue interface module has an applicator chamber on a proximal side of the tissue interface module and a tissue acquisition chamber on a distal side of the tissue interface module. The applicator chamber may include: an opening adapted to receive the applicator; an attachment mechanism positioned in the applicator chamber and adapted to attach the tissue interface module to the applicator; a sealing member positioned at a proximal side of the applicator chamber; and a vacuum interface positioned at a proximal side of the applicator chamber and adapted to receive a vacuum inlet positioned on a distal end of the applicator. The invention also includes corresponding methods.

Abstract: Prior applications disclosed power supply transmission voltage resulting in reduced line losses, with further energy conservation via luminous intensity control (dimming) of lamp(s) including LEDs.

Abstract: According to one exemplary embodiment of the present invention, a method for writing an arbitrary, two-dimensional pattern using interferometric lithography and classical techniques includes the steps of: (1) creating a pixel array defined by a number of pixels having specific coordinates; (2) mapping pixel information based on the desired pattern, the pixel information including a list of which pixels are activated to define the desired two-dimensional pattern; (3) controlling a relative strength of each pixel for indicating a feature height of a portion of the desired two-dimensional pattern; and (4) controlling a degree that one pixel is shifted in an x-direction and a y-direction relative to original coordinates of the pixel in order to define the desired two-dimensional pattern pixel by pixel.

Abstract: According to one exemplary embodiment of the present invention, a method for writing an arbitrary, two-dimensional pattern using interferometric lithography and classical techniques includes the steps of: (1) creating a pixel array defined by a number of pixels having specific coordinates; (2) mapping pixel information based on the desired pattern, the pixel information including a list of which pixels are activated to define the desired two-dimensional pattern; (3) controlling a relative strength of each pixel for indicating a feature height of a portion of the desired two-dimensional pattern; and (4) controlling a degree that one pixel is shifted in an x-direction and a y-direction relative to original coordinates of the pixel in order to define the desired two-dimensional pattern pixel by pixel.

Abstract: A switchable thermal circuit breaker (10) has an automatically resettable, current carrying thermostatic disc (14) cantilever mounted in a housing (12) and carries a movable contact (14b) into and out of electrical engagement with a stationary contact (14c). A disc coupling member (16) is pivotally mounted above the disc and has fingers (16e, 16f) to capture opposed sides of the disc so that the disc coupling member pivots concomitantly with movement of the disc. A radially extending blade (18c) of a pivot member is biased by a spring (18k) into engagement with a stop surface (16k) of the disc coupling member when the contacts are in the engaged position and is movable under the stop arm (16g) when the disc moves to the contacts disengaged position to prevent reengagement of the contacts.

Abstract: The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corresponding recombinant expression products of said nucleotide sequences, immunological reagents specifically reactive therewith, and procedures for identifying compounds which modulate the enzymatic activity of such expression products.

Abstract: The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corresponding recombinant expression products of said nucleotide sequences, immunological reagents specifically reactive therewith, and procedures for identifying compounds which modulate the enzymatic activity of such expression products.

Abstract: A thermally compensated circuit breaker has a movable contact assembly (24) which mounts a movable electrical contact (24m) for movement between open and closed contacts positions with a stationary electrical contact (26). The contacts are maintained in the closed circuits position by a latching mechanism (24b, 28g) which prevents opening of the contacts through an opening contacts force provided by a spring (24e). A current carrying trip arm (40a, 44a) deflects upon sufficient I2R heating to transfer motion to the latch to separate the latch (24b) from the latch receiving catch (28g) to trip the circuit breaker. The trip arm (40a, 44a) is part of a pivotably mounted actuator assembly (40, 44) having a movable end portion spaced from the pivot disposed adjacent a motion transfer member (28c). A calibration screw (42a) is located so that the longitudinal axis is in line with a movable end portion of the actuator assembly and the motion transfer member.

Abstract: The present invention relates to novel purified and isolated nucleotide sequences encoding mammalian Ca2+/calmodulin stimulated phosphodiesterases (CaM-PDEs) and cyclic-GMP-stimulated phosphodiesterases (cGS-PDEs). Also provided are the corresponding recombinant expression products of said nucleotide sequences, immunological reagents specifically reactive therewith, and procedures for identifying compounds which modulate the enzymatic activity of such expression products.

Abstract: A method, and corresponding system to implement the method, for managing access to concurrent software licenses at a licensee facility includes the steps of (i) determining whether a user has a valid software license to run a software application using a license management system (or a license server); and (ii) permitting a recognized user to run the software application (optionally with a punishment) if the license server is inaccessible. The permitting step can be performed only if the user has previously been authorized with a license management system. The punishment can be, for example, a time delay imposed between when the user attempts to run the software application and when the recognized user is permitted to run the software application. The time delay can be stored on a local workstation used by the user, as for example, an encrypted code key in a register of the local workstation.

Abstract: An electric circuit breaker (10) has a toggle mechanism (18) having two movable over center joints (3, 4) connected between a push-button (16) and a movable contact mechanism (30). When the push-button is depressed a first link rotates bringing the first movable over center joint (3) across a center position represented by a first imaginary straight line (1) to a stop surface (28). A spring member (36) provides a bias which acts on the second movable over center joint (4) normally maintaining the second movable joint against the stop surface so that with the two movable over center joints biased against the stop surface the movable contact mechanism is moved to a closed contact position when the push-button is depressed.