Abstract: The present invention provides a compound having the structure: wherein R1 is —(C2-C12 alkyl), -(alkenyl), -(alkynyl), -(cycloalkyl); R2 is H, halogen, —NO2, —CN, —CF3, —CF2H, —CH2OCH3, —CF2CH3, —CF2OCH3, -(alkyl), -(alkenyl), -(alkynyl), -(cycloalkyl), -(cycloalkylalkyl), -(heteroalkyl), -(heterocycle), -(heterocycloalkyl), -(aryl), -(heteroaryl), -(hydroxyalkyl), -(haloalkyl), -(alkylaryl), —OH, —O-(alkyl), —O-(alkenyl), —O-(alkynyl), —O-(haloalkyl), —O-(aryl), —O-(heteroaryl), —OCF3, SH, —S-(alkyl), —S-(alkenyl), —S-(alkynyl), —S-(aryl), —S-(heteroaryl), —NH2, —NH-(alkyl), —NH-(alkenyl), —NH-(alkynyl), —N-(alkyl)2, NH-(aryl), —NH-(heteroaryl), —CO2H, —CO2-(alkyl), —C(O)—NH2, —C(O)—NH-(alkyl), —C(O)—NH-(aryl), —SO2CH3 or —Si(CH3) 3; R3 is —OCH3, —OCH2CH3, —F or —Cl; and R4 is —OCH3, —OCH2CH3 or —SCH3; wherein when R1 is —CH2CH3, R3 is —OCH3, and R4 is —OCH3, then R2 is other than H, —CH3, —CH2CH3, —CH2CH2CH3, —CH(CH3)2, —CH2CH2CH2CH3, —CH2OH, —CH(OH) CH3, —OH, —OCH2CH3, —OCH2CH2CH3, —OCH(CH3)2, —SCH3,

Abstract: The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity, and/or modulate a gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against target gene expression.

Abstract: A computer system is structured to determine a density of particulate matter in a diesel particulate filter (DPF) sample. The computer system includes a processing circuit having a processor and a memory. The processing circuit is structured to generate a computed tomography (CT) scan-based image of the DPF sample; and, segment the CT scan-based image of the DPF sample into a plurality of regions. For at least one region from the plurality of regions, the processing circuit is structured to determine a density of a portion of the DPF sample corresponding to the at least one region of the CT scan-based image of the DPF sample and cause an electronic display of a user device to display the CT scan-based image including the at least one region and an indication of the density for the at least one region.

Abstract: A system includes a controller for an exhaust aftertreatment system including a SCR catalyst in exhaust gas-receiving communication with an engine and at least one reductant dosing system structured to provide reductant to the exhaust gas. The controller is structured to determine a ratio of NO to NO2 at or proximate an inlet of the SCR catalyst. The controller is further structured to command the at least one reductant dosing system to increase, decrease, or maintain an amount of reductant provided to the exhaust gas based on comparing the ratio of NO to NO2 to a previous NO to NO2 ratio.

Abstract: A method as disclosed herein generates objective projections of aggregate costs from a plurality of providers associated with different aspects of a healthcare procedure. An interface is selectively initiated with a first provider associated with a patient and a respective healthcare procedure. A data module is established for the patient based on projected cost data for aspects associated with the first provider for the procedure. Respective interfaces are selectively initiated between further providers and the hosted platform, wherein each interface receives projected cost data for aspects associated with the respective provider for the procedure. Upon determining a threshold amount of cost data has been received for each of the different aspects of the procedure, the platform enables selective access by the patient to an aggregated cost projection for the procedure, based entirely on the input data received by the hosted platform for the respective healthcare procedure.

Abstract: A system includes an exhaust aftertreatment system coupled to an engine, and a controller including at least one processor coupled to at least one memory device storing instructions that, when executed by the at least one processor, cause the controller to perform certain operations. The operations include estimating an aging of the exhaust aftertreatment system, and adjusting at least one of an entry temperature threshold or an exit temperature threshold for a thermal management mode for the exhaust aftertreatment system based on the aging of the exhaust aftertreatment system.

Abstract: A method for detecting a deviation in a flow meter parameter is provided. The method includes measuring a flow tube temperature in a plurality of locations; and calculating a temperature gradient based on the measured temperatures. The method also includes detecting a deviation in the flow meter parameter if the calculated temperature gradient exceeds a temperature gradient threshold.

Abstract: Interworking between different layer two (L2) medias using network tunnels is provided by receiving, at a virtual gateway network element (GNE), a packet from a first L2 media type network for transmission to a second L2 media type network under the control of a different entities, wherein the first and second L2 media type networks are incompatible for direct packet transmission; removing, at the virtual GNE, ethernet encapsulation from the packet; re-encapsulating, at a network device located between the virtual GNE and a packet network, the packet in a multi-protocol label switching (MPLS) encapsulation; forwarding, over the packet network, the packet from the network device to a digital communication channel (DCC) associated with the second L2 media type network; replacing, at the DCC, the MPLS encapsulation with a link access protocol (LAP) encapsulation; and transmitting the packet encapsulated with the LAP encapsulation to the second L2 media type network.

Abstract: Systems, apparatuses, and methods include a controller for an exhaust aftertreatment system including a SCR catalyst in exhaust gas-receiving communication with an engine and at least one reductant dosing system structured to provide reductant to the exhaust gas. The controller is structured to determine a concentration of one or more of NO and NO2 at or proximate an inlet of the exhaust aftertreatment system and based on a dynamic model of the SCR catalyst, information indicative of a concentration of NOx at or proximate an outlet of the exhaust aftertreatment system, and information indicative of an amount of stored reductant in the SCR catalyst. The controller is further structured to command the at least one reductant doser to increase, decrease, or maintain an amount of reductant provided to the exhaust gas based on the determined concentration of one or more of NO and NO2 in the exhaust gas.

Abstract: Interworking between different layer two (L2) medias using network tunnels is provided by receiving, at a virtual gateway network element (GNE), a packet from a first L2 media type network for transmission to a second L2 media type network under the control of a different entities, wherein the first and second L2 media type networks are incompatible for direct packet transmission; removing, at the virtual GNE, ethernet encapsulation from the packet; re-encapsulating, at a network device located between the virtual GNE and a packet network, the packet in a multi-protocol label switching (MPLS) encapsulation; forwarding, over the packet network, the packet from the network device to a digital communication channel (DCC) associated with the second L2 media type network; replacing, at the DCC, the MPLS encapsulation with a link access protocol (LAP) encapsulation; and transmitting the packet encapsulated with the LAP encapsulation to the second L2 media type network.

Abstract: A platform receives transaction information for an entity, where the transaction information identifies a plurality of transactions associated with the entity, and receives entity information associated with the entity. The platform identifies, using a first model, a selected set of transactions based on the transaction information and the entity information, where the first model outputs information identifying the selected set of transactions based on the selected set of transactions being associated with an event, a theme, or a transaction parameter. The platform determines, using a second model, potential modifications to a document based on the selected set of transactions, where the second model receives the information identifying the selected set of transactions or information identifying the event, the theme, or the transaction parameter, and where the second model outputs information identifying the potential modifications.

Abstract: Methods for asynchronously determining relational data integrity using cryptographic data structures are performed by systems and devices. Changes in current tables of relational databases are reflected in associated history tables. Cryptographic hybrid blockchain ledgers are updated with transaction records, for entry changes in current and history tables, including transaction information and hash values of corresponding entry changes. Hybrid blockchain ledgers also include root hash values of Merkle trees of transaction records in current blocks, and hash values of prior blocks. A current block receipt is asynchronously generated and provided as a single hash value from which the validity states of the tables and ledger are able to be verified. Cryptographic receipts of specific transactions reflected in table entry changes are generated and provide immutable evidence of specific transaction existence for users.

Abstract: A method includes acquiring nitrogen oxide (NOx) data indicative of a first amount of NOx in an exhaust flow exiting an engine and a second amount of NOx in the exhaust flow exiting an exhaust aftertreatment system coupled to the engine where the exhaust aftertreatment system including a selective catalytic reduction (SCR) system including a SCR catalyst; determining a NOx conversion efficiency fault is present within the exhaust aftertreatment system based on the first amount of NOx and the second amount of NOx; monitoring an actual amount of NOx in the exhaust flow downstream of the SCR catalyst; determining an expected amount of NOx downstream of the SCR catalyst; and determining the SCR catalyst is responsible for the NOx conversion efficiency fault in response to the actual amount of NOx differing from the expected amount of NOx by more than a threshold amount.

Abstract: A meter electronics (20) for detecting and identifying a change in a vibratory meter (5) is provided. The meter electronics (20) includes a processing system (202) including a storage system (204) configured to store a central tendency value of a meter verification parameter and dispersion value of the meter verification parameter. The processing system (202) is configured to obtain the central tendency value and the dispersion value from the storage system (204) and determine a probability based on the central tendency value and the dispersion value to detect if the central tendency value is different than a baseline value.

Abstract: A device may configure a browser to permit cash payments for online transactions. The device may monitor a browser session of the browser. The device may detect, during the browser session, navigation of the browser to a transaction page of a website. The transaction page may be configured to facilitate an online transaction with the website. The device may determine, based on detecting the navigation of the browser to the transaction page, that a cash payment is to be provided. The device may cause a validation code to be generated. The device may cause, based on the validation code being processed, a virtual transaction card to be generated. The device may facilitate, using virtual card information associated with the virtual transaction card, execution of the online transaction.

Abstract: An aftertreatment system for reducing constituents of an exhaust gas having a sulfur content includes: an oxidation catalyst; a filter disposed downstream of the oxidation catalyst; and a controller configured, in response to determining that the filter is to be regenerated and a desulfation condition being satisfied, to: cause a temperature of the oxidation catalyst to increase to a first regeneration temperature that is greater than or equal to 400 degrees Celsius and less than 550 degrees Celsius; cause the temperature of the oxidation catalyst to be maintained at the first regeneration temperature for a first time period; and after the first time period, cause the temperature of the oxidation catalyst to increase to a second regeneration temperature equal to or greater than 550 degrees Celsius.

Abstract: A platform receives transaction information for an entity, where the transaction information identifies a plurality of transactions associated with the entity, and receives entity information associated with the entity. The platform identifies, using a first model, a selected set of transactions based on the transaction information and the entity information, where the first model outputs information identifying the selected set of transactions based on the selected set of transactions being associated with an event, a theme, or a transaction parameter. The platform determines, using a second model, potential modifications to a document based on the selected set of transactions, where the second model receives the information identifying the selected set of transactions or information identifying the event, the theme, or the transaction parameter, and where the second model outputs information identifying the potential modifications.

Abstract: Vehicle inspection systems and methods are disclosed. A system disclosed includes a drone vehicle configured to fly in a vicinity of the damaged vehicle at an accident scene. The drone includes at least one camera for taking imagery of the damaged vehicle at an accident scene in support of a damage assessment and a frame coupling the drone vehicle and the at least one camera. A computing device is in communication with the at least one camera to receive the imagery from the at least one camera for purposes of damage assessment.

Abstract: A meter electronics (20) and a method for detecting and identifying a change in a vibratory meter (5) is provided. The meter electronics (20) includes an interface (201) configured to receive sensor signals (100) from a meter assembly (10) and provide information based on the sensor signals (100) and a processing system (202) communicatively coupled to the interface (201). The processing system (202) is configured to use the information to determine a first stiffness change (244) associated with a first location of a conduit (130, 130?) of the vibratory meter (5), determine a second stiffness change (254) associated with a second location of the conduit (130, 130?) of the vibratory meter (5), and determine a condition of the conduit (130, 130?) based on the first stiffness change and the second stiffness change.

Abstract: Methods for asynchronously determining relational data integrity using cryptographic data structures are performed by systems and devices. Changes in current tables of relational databases are reflected in associated history tables. Cryptographic hybrid blockchain ledgers are updated with transaction records, for entry changes in current and history tables, including transaction information and hash values of corresponding entry changes. Hybrid blockchain ledgers also include root hash values of Merkle trees of transaction records in current blocks, and hash values of prior blocks. A current block receipt is asynchronously generated and provided as a single hash value from which the validity states of the tables and ledger are able to be verified. Cryptographic receipts of specific transactions reflected in table entry changes are generated and provide immutable evidence of specific transaction existence for users.