Abstract: A method for designing a physical component of a drilling system includes defining input parameters of a first primitive in the drilling system, simulating the first primitive to obtain a performance parameter of the first primitive, designing, based on the performance parameter and to obtain a design, the physical component for the drilling system, and storing the design. The physical component has the input parameters of the first primitive. The input parameters include at least one control relationship between a first control point on the first primitive and a second control point.

Abstract: Biodegradable polymeric microparticle compositions containing one or more active agents, especially those useful for treating or preventing or one or more diseases or disorders of the eye, and methods of making and using thereof, are described. The microsphere compositions release an effective amount of the one or more active agents for a period greater than 14 days in vivo, preferably greater than 60 days in vivo, more preferably up to 73 days in vivo, more preferably greater than 90 days in vivo, even more preferably over 100 days in vivo, and most preferably greater than 107 days in vivo. In a preferred embodiment, the microparticle compositions contain one or more active agents such as AG1478 to induce nerve regeneration, specifically regeneration of the optic nerve useful for managing elevated intraocular pressure (IOP) in the eye.

Abstract: Methods, systems, and apparatus include computer programs encoded on a computer-readable storage medium, including a method for providing content. Search results responsive to a query are identified including a first search result in a top set of search results, the first search result associated with a first entity. A first eligible content item is identified for presentation along with the search results, the first eligible content item associated with the first entity. A combined content item is identified that is a combination of the first search result and first eligible content item and is to be presented as a search result responsive to the query. The combined content item is augmented including: identifying entities related to the first entity, identifying content items that are associated with the related entities, selecting at least one identified content item, and using content from the selected content items to augment the combined content item.

Abstract: A method for controllably producing a hematite-containing Fischer-Tropsch catalyst by combining an iron nitrate solution with a precipitating agent solution at a precipitating temperature and over a precipitation time to form a precipitate comprising iron phases; holding the precipitate from at a hold temperature for a hold time to provide a hematite containing precipitate; and washing the hematite containing precipitate via contact with a wash solution and filtering, to provide a washed hematite containing catalyst. The method may further comprise promoting the washed hematite containing catalyst with a chemical promoter; spray drying the promoted hematite containing catalyst; and calcining the spray dried hematite containing catalyst to provide a calcined hematite-containing Fischer-Tropsch catalyst.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer-readable storage medium, for evaluating a creative. A method includes: identifying one or more selection keywords that are associated with a creative, the selection keywords used in determining when the creative is shown in response to received content requests that include one or more request keywords; identifying matching criteria for comparing the selection keywords and the request keywords, the matching criteria defined by a range from an exact match to a broad match and including a matching threshold, in the range; establishing a bid modifier associated with the matching criteria, the bid modifier modifying a bid associated with the creative based on an extent of a match determined between the selection keywords and the request keywords for a given content request; and evaluating the creative responsive to received content requests based on the matching criteria and the bid modifier.

Abstract: Techniques are described herein that adaptively suppress harmonic distortion in an amplifier utilizing negative gain. The amplifier includes a first amplifier stage and a second amplifier stage, which are coupled in parallel. The first amplifier stage has a positive gain. The second amplifier stage has a negative gain to suppress total harmonic distortion of a system that includes the amplifier. The amplifier further includes shunt-peaking circuitry coupled to the first amplifier stage and the second amplifier stage to increase a maximum operating frequency at which the amplifier is capable of operating.

Abstract: Embodiments of apparatus and methods for voice based user enrollment with video assistance are described. In embodiments, an apparatus may include a face recognition module to identify a user from a first plurality of images and a lip motion detection module to detect the lip motion of the user from a second plurality of images. The apparatus may also include a recording module to activate a recording of the user. The apparatus may further include a user enrollment module, coupled with the recording module and the lip motion detection module, to establish a speaker model of the user based at least in part on the recording and the lip motion of the user. Other embodiments may be described and/or claimed.

Abstract: A communication system may include a number of communication channels operating in accordance with one or more communication standards. The channels may generate data clocks from one or more master clock signals. The phase of the data clocks may be aligned using phase detectors for determining respective phase relationships and using phase interpolators for adjusting respective clock phases. The communication system may include communication channels that operate at different data clock frequencies. These systems may divide their respective data clocks in order to achieve a common clock frequency for use in their phase alignment. The phase detectors and associated circuitry may be disabled to save power when not in use.

Abstract: The present invention provides methods for enhancing the synthesis of isotope labelled native proteins in specific biological pathways for the purpose of protein quantification and qualification. The invention provides reference samples for use in various mass-spectrometry-based methods of protein analysis.

Abstract: The invention provides a method and a composition for enhancing the dissolution and bioavailable properties of propofol (2, 6 diisopropyl phenol) for use as an intravenously administered anesthetic in mammals. The method produces a self-microemulsifyable emulsion base composition that is utilized in the production of a water-based microemulsion preparation. In a preferred two (2) component base composition, the base composition consists of: a surfactant, containing polyethylene glycol; and liquid propofol. The microemulsion is prepared by mixing the base composition with a carrier liquid, which results in the formation of a microemulsion containing concentrations of propofol of up to about 4% by weight of propofol to the volume of the microemulsion. In a four (4) component base composition, the base composition consists of: a surfactant, containing polyethylene glycol; liquid propofol; a water-immiscible solvent; and ethanol.

Abstract: A method and composition are presented for enhancing the dissolution and bioavailable properties of CoQ10 nutritional supplements and/or therapeutic agents for a human being and other mammals. The method includes preparing an anhydrous self-microemulsifying base composition by combining: CoQ10, a water-immiscible, and a non-ionic surfactant, containing polyethylene glycol. For an orally administered CoQ10 nutritional supplement in a capsule formulation, a unit dosage from the composition is added to a dissolvable capsule, preferably a soft gelatin capsule, in order to form the nutritional supplement. When a capsule containing the self-microemulsifying composition enters the digestive tract, the temperature of the body's digestive juices warms the composition, causing any of the CoQ10 that may have re-crystallized out of the composition to become re-dissolved into the composition before the capsule dissolves. The re-dissolution of CoQ10 is bioavailable when the capsule dissolves.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer-readable storage medium, for comparing a request entity to a campaign entity. A method includes: identifying a campaign associated with a content sponsor, the campaign having an associated creative for presentation to users and selection criteria for use in evaluating when to present the creative in response to received requests for content; receiving at least one keyword from the content sponsor to be used as selection criteria; identifying an entity from a plurality of entities to associate with the keyword; storing the identified entity along with the keyword in association with the campaign; and using the keyword and the identified entity when evaluating the received requests for content.

Abstract: Clip-type cable management apparatus and methods are disclosed. In one embodiment, a first jaw and a second jaw having interleaved tines in a predetermined configuration are coupled by a hinge pin around which a torsion spring is disposed to urge said first jaw and said second jaw pivotally toward a close position so as to securely retain a cable being folded or coiled into a bundle of cable segments. Such cable management is further enhanced with additional features, optimized structures, and operating methods.

Abstract: A method of preparing a spray dried catalyst by combining spray dried catalyst particles with wax so the spray dried catalyst particles are coated with wax, yielding wax coated catalyst particles, and shaping the wax coated catalyst to provide shaped wax coated catalyst. A method of activating Fischer-Tropsch catalyst particles containing oxides by contacting the catalyst particles with a reducing gas in an activation vessel to produce an activated catalyst, wherein contacting is performed in the absence of a liquid medium under activation conditions. A system for activating a Fischer-Tropsch catalyst containing an activation reactor configured to introduce an activation gas to a fixed or fluidized bed of the Fischer-Tropsch catalyst in the absence of a liquid medium and at least one separation device configured to separate a gas stream comprising entrained catalyst fines having an average particle size below a desired cutoff size from the activation reactor.

Abstract: Techniques are described herein that adaptively suppress harmonic distortion in an amplifier utilizing negative gain. The amplifier includes a first amplifier stage and a second amplifier stage, which are coupled in parallel. The first amplifier stage has a positive gain. The second amplifier stage has a negative gain to suppress total harmonic distortion of a system that includes the amplifier. The amplifier further includes shunt-peaking circuitry coupled to the first amplifier stage and the second amplifier stage to increase a maximum operating frequency at which the amplifier is capable of operating.

Abstract: Clip-type cable management devices are disclosed. In one embodiment, a first primary jaw (110) and a second primary jaw (112) having interleaved tines are coupled by a hinge pin (114) around which a primary torsion spring (116) is disposed to urge the primary jaws pivotally close. A secondary jaw (118) is disposed on the hinge pin and urged by a secondary torsion spring (120) pivotally toward the second primary jaw. A lever pin (122) is disposable in either a storage position or a working position on the first primary jaw so as to differentiate the pivotal opening of the secondary jaw, which is operable through the primary jaws. Resulting device is compact, quick and easy to operate, and packed with an array of functionalities applicable to cables of various sizes.

Abstract: A method for designing a secondary cutting structure for use in a bottom hole assembly, the method including defining initial design parameters for the secondary cutting structure and analyzing forces acting on the secondary cutting structure. Additionally, the method includes modifying at least one design element of the secondary cutting structure and simulating an effect of the modifying on both the secondary cutting structure and a primary cutting structure to determine if an improved condition is met. Also, a method for designing a drilling tool assembly, the method including defining initial drilling tool assembly design parameters including a primary cutting structure and a secondary cutting structure, and simulating a dynamic response of the drilling tool assembly.

Abstract: A communication system may include a number of communication channels operating in accordance with one or more communication standards. The channels may generate data clocks from one or more master clock signals. The phase of the data clocks may be aligned using phase detectors for determining respective phase relationships and using phase interpolators for adjusting respective clock phases. The communication system may include communication channels that operate at different data clock frequencies. These systems may divide their respective data clocks in order to achieve a common clock frequency for use in their phase alignment. The phase detectors and associated circuitry may be disabled to save power when not in use.

Abstract: Systems and methods for proximity detection between electronic devices are disclosed. One or more electronic devices transmit signals to a proximity server, which determines whether the first electronic device may be proximate the second electronic device. The proximity server transmits a signal to the first electronic device and the second device, and in response to the signal, the first and second electronic devices activate an environmental sensor, collect at least one sample of environmental data, extract at least one feature set of the environmental data, generate a first obscured feature from the feature set, transmit the first and second obscured feature sets to the proximity server. The proximity server uses the first obscured feature set and the second obscured feature set to determine whether the first electronic device and the second electronic device are proximate.