Abstract: Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.

Abstract: The invention provides combination therapy, wherein one or more other therapeutic agents are administered agents are administered with peptide epoxyketones or a pharmaceutically acceptable salt thereof. Another aspect of the invention relates to treating cancer with a peptide epoxyketone administered in combination with another therapeutic agent.

Abstract: Electronic modules having complex contact structures may be formed by encapsulating panels containing pluralities of electronic modules delineated by cut lines and having conductive interconnects buried within the panel along the cut lines. Holes defining contact regions along the electronic module sidewall may be cut into the panel along the cut lines to expose the buried interconnects. The panel may be metallized, e.g. by a series or processes including plating, on selected surfaces including in the holes to form the contacts and other metal structures followed by cutting the panel along the cut lines to singulate the individual electronic models. The contacts may be located in a conductive grove providing a castellated module.

Abstract: Remote notification of alarms improves security. When an alarm is detected by a security system, a notification message is sent to notify a user or emergency responder. If video data is requested, only certain locations are permitted access to outputs from cameras.

Abstract: This disclosure provides methods of treating a cancer in a patient using a peptide epoxyketone proteasome inhibitor in combination with a PIM kinase inhibitor.

Abstract: A financial analysis system retrieves data from a myriad of public and/or private data sources to develop a financial model that takes into account many life situations that an individual may experience. Together with detailed information regarding the individual such as age, race/ethnic background, marital status, occupation, family information, health data, career data, place of living/work, expected future expenditures, goals, lifestyles, etc. From these, the financial analysis system predicts future financial situations such as savings/assets, cash flow, etc., based upon the individual's data in view of the myriad of data sources that are available, providing a more accurate view of what the future financial situation shall be for that individual.

Abstract: Electronic modules having complex contact structures may be formed by encapsulating panels containing pluralities of electronic modules delineated by cut lines and having conductive interconnects buried within the panel along the cut lines. Holes defining contact regions along the electronic module sidewall may be cut into the panel along the cut lines to expose the buried interconnects. The panel may be metallized, e.g. by a series or processes including plating, on selected surfaces including in the holes to form the contacts and other metal structures followed by cutting the panel along the cut lines to singulate the individual electronic models. The contacts may be located in a conductive grove providing a castellated module.

Abstract: Disclosed herein are latex compositions and asphalt formulations comprising the latex compositions. In some embodiments, the latex compositions include a styrene-butadiene copolymer and polyphosphoric acid represented by the formula, Hn+2PnO3n+1, wherein n is an integer from 2 to 30. The latex composition can be used to prepare polymer-modified asphalt emulsions and hot mix asphalt compositions. The asphalt formulations can be prepared by contacting asphalt with a latex composition as described herein and a sulfur curing agent. Methods of coating a surface comprising applying an asphalt formulation as described herein to the surface are also disclosed.

Abstract: A particular method includes generating, at a device, a first digital identifier of a first software component. The method also includes performing a comparison of the first digital identifier to one or more second digital identifiers in a database. The method further includes generating first data indicating recommended procedures to analyze the first software component based on the comparison.

Abstract: A non-carboxylated styrene-butadiene copolymer, preparation method and use thereof are provided. The non-carboxylated styrene-butadiene copolymer is prepared by hot polymerization in the absence of acid monomers and is used in asphalt-based systems such as asphalt emulsions.

Abstract: The invention provides combination therapy, wherein one or more other therapeutic agents are administered agents are administered with peptide epoxyketones or a pharmaceutically acceptable salt thereof. Another aspect of the invention relates to treating cancer with a peptide epoxyketone administered in combination with another therapeutic agent.

Abstract: A media delivery scheme distributes a stream of media files to a group of users while allowing individual users to request specific media files. In one embodiment, a media server maintains a playlist of media files to broadcast, and requests for media must satisfy certain restrictive criteria to be added to the playlist. In another aspect of a preferred embodiment, the media server schedules requested media so as to comply with provisions of the DMCA.

Abstract: The invention provides combination therapy, wherein one or more other therapeutic agents are administered agents are administered with peptide epoxyketones or a pharmaceutically acceptable salt thereof. Another aspect of the invention relates to treating cancer with a peptide epoxyketone administered in combination with another therapeutic agent.

Abstract: A non-carboxylated styrene-butadiene copolymer, preparation method and use thereof are provided. The non-carboxylated styrene-butadiene copolymer is prepared by hot polymerization in the absence of acid monomers and is used in asphalt-based systems such as asphalt emulsions.

Abstract: This disclosure features modified release pharmaceutical formulations (e.g., extended release pharmaceutical formulations; e.g., solid dosage forms, e.g., tablets) that are useful for the oral administration of oprozomib, or a pharmaceutically acceptable salt thereof, to a human or animal subject as well as methods of making and using the formulations.

Abstract: Methods of treating a tumor in a subject and methods of determining a treatment regimen for a subject with a tumor are provided herein. In exemplary aspects, the methods comprise measuring the level of expression of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof. In exemplary aspects, the subject is a subject from which a sample was obtained, wherein the level of immunoglobulin, FCGR2B, a gene listed in Table 4, or a combination thereof, has been measured from the sample. Related kits, computer readable-storage media, systems, and methods implemented by a processor in a computer are further provided.

Abstract: ABSTRACT The invention provides combination therapy, wherein one or more other therapeutic agents are administered agents are administered with peptide epoxyketones or a pharmaceutically acceptable salt thereof. Another aspect of the invention relates to treating cancer with a peptide epoxyketone administered in combination with another therapeutic agent.