Abstract: A method of treating plasma with a pretreatment solution that has a physiologically compatible spray dry stable acidic substance (SDSAS) and an amino acid, prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compositions related to plasma dried by the methods of the present invention.

Abstract: A variable diffuser includes a backing plate, a shroud, a diffuser body between the backing plate and the shroud, a plurality of passages through the diffuser body, and a valve adjacent to the shroud and the diffuser body. The valve movably occludes a portion of the plurality of passages.

Abstract: A device for treatment of a vascular defect within a patient's vasculature includes a self-expanding permeable shell having a proximal end, a distal end, and a longitudinal axis, the shell comprising a plurality of elongate resilient filaments having a braided structure, wherein the filaments are secured at at least one of the proximal end or the distal end of the permeable shell, wherein the permeable shell has a radially constrained elongated state configured for delivery within a microcatheter and has an expanded state with an axially shortened configuration relative to the radially constrained state, the permeable shell having a plurality of openings formed between the braided filaments, wherein the permeable shell in its expanded state comprises a plurality of circumferentially-arrayed lobes.

Abstract: A filter cartridge that includes a canister configured to hold a filter element. The canister has a canister body with an open end and an end closure. The end closure has a central annular element locating feature, and an annular frame portion circumscribing the central annular element locating feature. The canister body and end closure have cooperating geometry for retaining the end closure to the open end of the canister. The cooperating geometry includes an axial retention mechanism for maintaining an attachment between the canister and the end closure. The axial retention mechanism is configured to maintain the attachment solely via mechanical interference.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: Memory having internal processors, and methods of data communication within such a memory are provided. In one embodiment, an internal processor may concurrently access one or more banks on a memory array on a memory device via one or more buffers. The internal processor may be coupled to a buffer capable of accessing more than one bank, or coupled to more than one buffer that may each access a bank, such that data may be retrieved from and stored in different banks concurrently. Further, the memory device may be configured for communication between one or more internal processors through couplings between memory components, such as buffers coupled to each of the internal processors. Therefore, a multi-operation instruction may be performed by different internal processors, and data (such as intermediate results) from one internal processor may be transferred to another internal processor of the memory, enabling parallel execution of an instruction(s).

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: An assembly for use in an aircraft includes a housing having an inlet and an outlet and a flow path for an airflow extends between the inlet and the outlet. The assembly additionally includes a rotatable portion including a rotor mounted within the housing between the inlet and the outlet along the flow path. The rotor has a body including a first side facing the inlet, a second opposite side, and a plurality of impeller blades protruding from the first side. An axial flux electric motor includes a motor rotor having at least one first flux element and a motor stator. The at least one first flux element is integrated into the rotatable portion and the motor stator is remote from the flow path.

Abstract: An air cycle machine for use in environmental control system of an aircraft includes a first wheel having a rotatable portion and a second wheel operably coupled to the rotatable portion of the first wheel. An axial flux electric motor includes a motor rotor having at least one first flux element and a motor stator including at least one second flux element. The at least one first flux element is integrated into the rotatable portion of the first wheel.

Abstract: Disclosed is a cabin air compressor (CAC) of an aircraft environmental control system, the CAC having: a CAC case defining a forward end and an aft end axially spaced apart axially from the forward end, wherein the forward end defines a compressor inlet; and a supplemental cooling passage defined by the CAC case, wherein the supplemental cooling passage is configured to direct a supplemental cooling medium through it.

Abstract: The present disclosure provides absorption refrigeration systems, assemblies and methods utilizing waste heat for climate control and/or cooling (e.g., electric systems cooling; electronics cooling; motor cooling; generator cooling; oil cooling; etc.). More particularly, the present disclosure provides absorption refrigeration systems, assemblies and methods utilizing waste heat (e.g., from aviation/aerospace systems, such as hybrid-electric/electric aircraft/aerospace systems or the like) for climate control and/or cooling (e.g., electronics cooling; motor cooling; generator cooling; oil cooling; electric systems cooling for energy savings on aviation/aerospace systems, such as hybrid-electric/electric aircraft/aerospace systems). In example embodiments, the waste heat utilization provides up to 100% of the energy control system (ECS) input energy, and certain configurations allow for substantially no electric energy input (e.g., allows for gravity flow only).

Abstract: A variable channel diffuser includes a shroud, a backing plate, a channel plate adjacent to the backing plate, a floor plate adjacent to the shroud, standoffs formed on the floor plate, and recessed areas formed in the channel plate. The channel plate is between the shroud and the backing plate. The floor plate is between the shroud and the channel plate and is movable relative to the channel plate. The standoffs and the recessed areas define channels for fluid flow. Each channel has an area which is variable through movement of the floor plate relative to the channel plate.

Abstract: A variable vaneless diffuser includes a shroud, a backing plate, a divider plate adjacent to the backing plate, a floor plate adjacent to the shroud, a plurality of standoffs formed on the divider plate, and a plurality of clearance slots formed in the floor plate. The divider plate is between the shroud and the backing plate. The floor plate is between the shroud and the divider plate and is movable relative to the divider plate. The plurality of standoffs and the plurality of clearance slots define a flow path for fluid flow. The flow path has an area which is variable through movement of the floor plate relative to the divider plate.

Abstract: A seal plate for a rotary machine includes a hub centered on a central axis of the rotary machine, a disk portion extending radially outwards from the hub, and a variable lattice structure in an interior of the seal plate. The variable lattice structure includes a first region of the seal plate having a first lattice structure, and a second region of the seal plate having a second lattice structure. The second lattice structure of the second region is denser than the first lattice structure of the first region. The second region is a deflection region, a stress region, or an energy containment region of the seal plate.

Abstract: A compressor includes a rotor driven by a shaft and configured to compress air and a motor for driving the shaft. At least one bearing facilitates rotation of the shaft. A motor cooling loop is configured to provide motor cooling air to the motor. A bearing cooling loop is configured to provide bearing cooling air to the at least one bearing. A bearing support is configured to support the least one bearing, the bearing support includes an opening. A duct is configured to communicate air from the opening to an inlet of the compressor. A method for cooling a compressor is also disclosed.

Abstract: The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port.

Abstract: An additively manufactured component includes an outer shell, the outer shell enclosing a space therein. An inner lattice structure is in the space of the outer shell. Interspaces are formed in the inner lattice structure. A method of forming an additively manufactured component includes evacuating a chamber in which the additively manufactured component will be formed, and forming in the chamber layer by layer an outer shell enclosing a core. The core includes a lattice structure with interspaces formed in the lattice structure.

Abstract: A rotor blade for a turbomachine includes a base, a tip opposite the base in a spanwise direction, a leading edge, and a trailing edge opposite the leading edge in a chordwise direction. A pressure surface extends from the leading edge to the trailing edge, and extends from the base to the tip. A suction surface extends from the leading edge to the trailing edge, and extends from the base to the tip. The tip includes a tip seal additively manufactured to the rotor blade. The tip seal includes a first portion with a first composition and a second portion with a second composition different from the first composition.

Abstract: A seal plate for a rotary machine includes a hub centered on a central axis of the rotary machine, a disk portion extending radially outwards from the hub, and a variable lattice structure in an interior of the seal plate. The variable lattice structure includes a first region of the seal plate having a first lattice structure, and a second region of the seal plate having a second lattice structure. The second lattice structure of the second region is denser than the first lattice structure of the first region. The second region is a deflection region, a stress region, or an energy containment region of the seal plate.

Abstract: A liquid filter in the form of a filter element or a filter cartridge provides torsion locking relative to a filter head when the housing of such filter is threaded onto a filter head. Many embodiments employ a filter that includes a nipple portion at a top end with the torsion lock detent provided outboard of the nipple portion or integrated into the nipple portion. Many embodiments employ a simplified shoulder transition region at the top end of a torsion locked filter element. Valve actuation and/or filter differentiation is used in some embodiments. Different torsion locking arrangements, deformable thread profiles and other liquid filter features are disclosed.