Abstract: A mechanical ventilation device includes at least one electronic controller configured to receive imaging data related to a dimension of a diaphragm of a patient during inspiration and expiration while the patient undergoes mechanical ventilation therapy with an associated mechanical ventilator; calculate a pressure value (Pl, DPl) of a chest of the patient based on at least the imaging data; and when the calculated pressure value (Pl, DPl) does not satisfy an acceptance criterion, at least one of output an alert indicative of the calculated pressure value (Pl, DPl) failing to satisfy the acceptance criterion; and output a recommended adjustment to one or more parameters of the mechanical ventilation therapy delivered to the patient.

Abstract: A diaphragm imaging device includes at least one electronic processor programmed to perform a diaphragm imaging method including receiving ultrasound imaging data of a diaphragm of a patient, the ultrasound imaging data being acquired by an associated ultrasound imaging probe with the probe at a plurality of different observable probe angles (?obs); for each observable probe angle, determining a corresponding apparent thickness (dI) of the diaphragm of the patient from the received ultrasound data acquired at that observable probe angle; and estimating a thickness (dD) of the diaphragm of the patient based at least on the apparent thicknesses (dI).

Abstract: A diaphragm measurement device includes a non-transitory storage medium storing a patient-specific registration model for referencing ultrasound imaging data to a reference frame. At least one electronic processor is programmed to perform a diaphragm measurement method including receiving ultrasound imaging data of a diaphragm of a patient during inspiration and expiration while the patient undergoes mechanical ventilation therapy with a mechanical ventilator; calculating a diaphragm thickness metric based on the received ultrasound imaging data of the diaphragm of the patient referenced to the reference frame using the patient-specific registration model; and displaying, on a display device, a representation of the calculated diaphragm thickness metric.

Abstract: A mechanical ventilation assistance device includes at least one electronic controller configured to receive positional data of a patient; determine a position of an imaging device configured to obtain imaging data of the patient based on the received positional data; and display, on a display device, a representation of the determined position of the imaging device.

Abstract: A diaphragm measurement system (1) includes at least one electronic processor (13) programmed to perform a diaphragm measurement method (100) including receiving ultrasound imaging data (24) of a diaphragm of a patient over a time period encompassing multiple breaths; receiving respiration data of the patient over the time period; calculating a diaphragm thickness metric based on the received ultrasound imaging data of the diaphragm and the received respiration data; and displaying, on a display device (14), a representation (30) of the calculated diaphragm thickness metric.

Abstract: A diaphragm measurement device (1) includes at least one electronic processor (13) programmed to perform a diaphragm measurement method (100) including receiving ultrasound imaging data of a dimension of a diaphragm of a patient during inspiration and expiration while the patient undergoes mechanical ventilation therapy with a mechanical ventilator (2); receiving respiratory data of the patient during inspiration and expiration while the patient undergoes the mechanical ventilation therapy; calculating a diaphragm thickness metric based on the received ultrasound imaging data of the diaphragm of the patient and the received respiratory data; and displaying, on a display device (14), a representation (30) of the calculated diaphragm thickness metric.

Abstract: A medical device for treating an associated patient includes a bronchial sensor device configured to measure fluid pressure in a bronchus of the associated patient; and an electronic controller configured to: receive the fluid pressure data from the bronchial sensor device; and calculate a fluid flow measurement through the bronchus based on the measured fluid pressure.

Abstract: A non-transitory storage medium stores instructions readable and executable by at least one electronic processor to receive clinical data for a current patient (P); search a database of CT scans and/or patient-specific mechanical ventilation models for other patients using the clinical data for the current patient as a search criterion to identify a similar patient in the database and similar patient data (S) comprising a CT scan and/or a patient-specific mechanical ventilation model for the similar patient; determine a patient-specific mechanical ventilation model for the current patient based on the CT scan and/or patient-specific mechanical ventilation model for the similar patient; generate ventilator configuration data for mechanically ventilating the current patient based on the determined patient-specific mechanical ventilation model for the current patient.

Abstract: A medical device for treating an associated patient includes an electronic processing device configured to receive ventilation waveform data during mechanical ventilation of the associated patient and to perform a patient-ventilator asynchrony monitoring method including detecting initial patient-ventilator asynchrony events during a training period of the mechanical ventilation by analysis of measurements of the associated patient acquired during the training period; training a machine learning (ML) component to analyze ventilation waveform data to detect patient-ventilator asynchrony events using the ventilation waveform data received during the training period with labels indicating the initial patient-ventilator asynchrony events; applying the patient-specific ML component to the ventilation waveform data received after the training period to detect patient-ventilator asynchrony events occurring after the training period; and a display device configured to display an indication of patient-ventilator async

Abstract: A respiration monitoring device comprises an electronic controller configured to: receive an audio signal that is acoustically coupled with an airway of a patient receiving mechanical ventilation therapy from a mechanical ventilator; map the audio signal to one or more lung disease or injury condition categories; and at least one of: display the mapped one or more lung disease or injury condition categories on a display device; and determine a recommended adjustment to one or more parameters of the mechanical ventilation therapy delivered to the patient based at least on the mapped lung disease or injury condition categories and displaying the recommended adjustment on the display device.

Abstract: A mechanical ventilation device comprising at least one electronic controller is configured to receive images of lungs of a patient undergoing mechanical ventilation therapy with a mechanical ventilator, the images being acquired over time and having timestamps; process the images to generate timeline images at corresponding discrete time points; and display a timeline of the timeline images on a display device.

Abstract: A mechanical ventilation device comprising at least one electronic controller configured to receive imaging data and transpulmonary pressure data associated with a lung of a patient; perform deformable image registration of the inhalation image and the exhalation image to produce a relative compliance or elasticity map of the lungs; convert the relative compliance or elasticity map of the lungs to a quantitative compliance or elasticity map of the lungs based on the inhale transpulmonary pressure and the exhale transpulmonary pressure; and display the information relating to or derived from the quantitative compliance or elasticity map on a display device.

Abstract: A respiratory monitoring device includes an electronic controller configured to: analyze an audio signal triggered during inspiratory and expiratory phases of a patient receiving mechanical ventilation therapy from a mechanical ventilator, the audio signal being acoustically coupled into the airway of the patient, to determine resonant frequencies of the airway; determine a shift in the resonant frequencies between the inspiratory and expiratory phases to determine a presence of pendelluft inside of a lung of the patient; and output an indication of the presence of pendelluft.

Abstract: A mechanical ventilation device comprises at least one electronic controller configured to: receive ultrasound data related to a thickness of a diaphragm of a patient during inspiration and expiration while the patient undergoes mechanical ventilation therapy with a mechanical ventilator; calculate a diaphragm thickness metric based on at least the ultrasound data; and when the calculated diaphragm thickness metric does not satisfy an acceptance criterion, at least one of: output an alert indicative of the calculated diaphragm thickness metric failing to satisfy the acceptance criterion; and output a recommended adjustment to one or more parameters of the mechanical ventilation therapy delivered to the patient.

Abstract: An intubation assistance device includes an electronic controller configured to: generate a patient respiratory tract geometry model of at least a portion of a human respiratory tract by inputting one or more patient variables into a statistical shape model (SSM) of at least a portion of the human respiratory tract; select a recommended endotracheal tube (ETT) size by modeling at least one ETT model inserted into the patient respiratory tract geometry model to form a virtual fit model and estimating at least one fit parameter based on the virtual fit model; and display the recommended ETT size on a display device.

Abstract: A sensor system for measuring a velocity of a fluid flowing through a channel includes a heating element for heating the fluid. The heating element is provided with a predetermined level of power during operation. The sensor system further includes a primary electronic circuit having a primary resonance frequency which is temperature dependent. The temperature of the primary electronic circuit is determined by heat transferred from the heating element to the fluid flowing through the channel. In addition, the sensor system also includes a transducer arrangement configured to generate a measurement signal indicative of the velocity of the fluid flowing through the channel. The measurement signal is based on the primary resonance frequency.

Abstract: A thermal flow sensor integrated circuit for sensing flow in a channel based on temperature measurements, the integrated circuit having a temperature sensing element (30) on a front side of the integrated circuit arranged to face the channel, and a bond pad (60, 200) coupled electrically to the temperature sensing element, for making electrical contact off the integrated circuit, the bond pad being arranged to face away from the channel. By having the bond pad facing away from the channel, the space needed for the bond pad and any connections to it need not extend beyond the temperature sensing element and get in the way of the channel. Hence the temperature sensing element can be located closer to the channel or in the channel to enable measurements with better response time and sensitivity.

Abstract: A nebulizer comprises a head detachably coupled to a body. The head comprises the nebulizer, an air channel and a flow sensor. A nebulized liquid is released in an air channel that ends in a mouth piece through which a user inhales and exhales. The inhaling and exhaling causes a flow in the air channel which is detected with the flow sensor. The nebulizer is controlled by controls and sensors included in the body.

Abstract: A sensor for detecting bubbles in gas phase present in a liquid flowing through a flow path. The sensor can include a heating element for heating the liquid, which can be provided with a predetermined level of power at least during detecting, and a transducer arrangement arranged for generating a measurement signal indicative for the temperature of the heating element. The sensor furthermore can include a comparator arrangement for comparing a measurement value of the measurement signal with a predetermined threshold level, which can correspond to a reference temperature attainable by the heating element in response to the predetermined level of power and a minimum velocity attainable by the liquid in the flow path. Based on the latter comparison, the comparator arrangement can generate an output signal indicative for a possible presence of bubbles in gas phase.

Abstract: A nebulizer (10) comprises a head detachably coupled to a body. The head comprises nebulizing means (42, 40, 44), an air channel (50) and a flow sensor (52). A nebulized liquid is released in an air channel (50) that ends in a mouth piece 70 through which a user inhales (5) and exhales (7). The inhaling and exhaling causes a flow in the air channel which is detected with the flow sensor (52). The nebulizing means are controlled by control means (60, 62) included in the body.