Abstract: Engineered bispecific antibodies with charge pairs introduced at the interface of CHI and CL alone or in combination with other charge pairs at the interface of VH and VL are described. Also described are anti-CD47/anti-CLDN18.2 and anti-CD3/anti-DLL3 bispecific antibodies and antigen-binding fragments thereof. Also described are nucleic acids encoding the bispecific antibodies, compositions comprising the bispecific antibodies, and methods of producing the bispecific antibodies and using the bispecific antibodies for treating or preventing diseases, such as cancer and/or associated complications.

Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of making and using the same, e.g., for treatment of IL-33 mediated disorders (e.g., ocular disorders such as AMD (e.g., geographic atrophy (GA)).

Abstract: An automated drone security system for surveilling a location includes one or more drones with onboard sensors and an imaging device for measuring surveillance data. The surveillance data may include images, telemetry data, infrared data, or other detectable information of the location. Drones may be capable of executing one or multiple flight operations as well as storing and transmitting the surveillance data to a server assembly operable for coordinating the drone and receiving the surveillance data. A drone dock may be included for drone launching, landing, and/or storing the drones. A user computing device may be in communication with the server assembly and the drone(s), the user computing device being capable of receiving user input and displaying surveillance data from the drone. Flight operations associated with surveilling the location may be automatically and/or manually controlled by the user computing device and/or or the server assembly in connection with the location.

Abstract: A protective face mask may comprise an outer housing including a plurality of ventilation holes, and an inner housing detachably coupled to the outer housing, the inner housing configured to cover a nose and a mouth of a user, the inner housing including a second plurality of ventilation holes. The protective face mask may also include a replaceable filter configured to be received in a space between the inner housing and the outer housing. In some embodiments, the protective face mask includes a dual chamber breathing design configured to reduce moisture collection within the mask.

Abstract: An automated drone security system for surveilling a location includes one or more drones with onboard sensors and an imaging device for measuring surveillance data. The surveillance data may include images, telemetry data, infrared data, or other detectable information of the location. Drones may be capable of executing one or multiple flight operations as well as storing and transmitting the surveillance data to a server assembly operable for coordinating the drone and receiving the surveillance data. A drone dock may be included for drone launching, landing, and/or storing the drones. A user computing device may be in communication with the server assembly and the drone(s), the user computing device being capable of receiving user input and displaying surveillance data from the drone. Flight operations associated with surveilling the location may be automatically and/or manually controlled by the user computing device and/or or the server assembly in connection with the location.

Abstract: An automated drone security system for surveilling a location includes one or more drones with onboard sensors and an imaging device for measuring surveillance data. The surveillance data may include images, telemetry data, infrared data, or other detectable information of the location. Drones may be capable of executing one or multiple flight operations as well as storing and transmitting the surveillance data to a server assembly operable for coordinating the drone and receiving the surveillance data. A drone dock may be included for drone launching, landing, and/or storing the drones. A user computing device may be in communication with the server assembly and the drone(s), the user computing device being capable of receiving user input and displaying surveillance data from the drone. Flight operations associated with surveilling the location may be automatically and/or manually controlled by the user computing device and/or or the server assembly in connection with the location.

Abstract: An automated drone security system for surveilling a location includes one or more drones with onboard sensors and an imaging device for measuring surveillance data. The surveillance data may include images, telemetry data, infrared data, or other detectable information of the location. Drones may be capable of executing one or multiple flight operations as well as storing and transmitting the surveillance data to a server assembly operable for coordinating the drone and receiving the surveillance data. A drone dock may be included for drone launching, landing, and/or storing the drones. A user computing device may be in communication with the server assembly and the drone(s), the user computing device being capable of receiving user input and displaying surveillance data from the drone. Flight operations associated with surveilling the location may be automatically and/or manually controlled by the user computing device and/or or the server assembly in connection with the location.

Abstract: An automated drone security system for surveilling a location includes one or more drones with onboard sensors and an imaging device for measuring surveillance data. The surveillance data may include images, telemetry data, infrared data, or other detectable information of the location. Drones may be capable of executing one or multiple flight operations as well as storing and transmitting the surveillance data to a server assembly operable for coordinating the drone and receiving the surveillance data. A drone dock may be included for drone launching, landing, and/or storing the drones. A user computing device may be in communication with the server assembly and the drone(s), the user computing device being capable of receiving user input and displaying surveillance data from the drone. Flight operations associated with surveilling the location may be automatically and/or manually controlled by the user computing device and/or or the server assembly in connection with the location.

Abstract: A partitioned application environment is disclosed. In various embodiments, a request associated with an application environment in which an application is running is received from the application. A determination is made to fulfill the request at least in part via a call to a node at which application code associated with the application is running in an application environment partition provided at the node. A call associated with the request is sent to the node, based at least in part on the determination.

Abstract: An automated drone security system for surveilling a location includes one or more drones with onboard sensors and an imaging device for measuring surveillance data. The surveillance data may include images, telemetry data, infrared data, or other detectable information of the location. Drones may be capable of executing one or multiple flight operations as well as storing and transmitting the surveillance data to a server assembly operable for coordinating the drone and receiving the surveillance data. A drone dock may be included for drone launching, landing, and/or storing the drones. A user computing device may be in communication with the server assembly and the drone(s), the user computing device being capable of receiving user input and displaying surveillance data from the drone. Flight operations associated with surveilling the location may be automatically and/or manually controlled by the user computing device and/or or the server assembly in connection with the location.

Abstract: A partitioned application environment is disclosed. In various embodiments, a request associated with an application environment in which an application is running is received from the application. A determination is made to fulfill the request at least in part via a call to a node at which application code associated with the application is running in an application environment partition provided at the node. A call associated with the request is sent to the node, based at least in part on the determination.

Abstract: A partitioned application environment is disclosed. In various embodiments, a request associated with an application environment in which an application is running is received from the application. A determination is made to fulfill the request at least in part via a call to a node at which application code associated with the application is running in an application environment partition provided at the node. A call associated with the request is sent to the node, based at least in part on the determination.

Abstract: A method and apparatus for performing complex mathematical calculations. The apparatus includes a multicore processor 10 where the cores 15 are connected 20 into a net with the processors on the periphery 15a primarily dedicated to input/output functions and distribution of tasks to the central processors 15b-h of the net. The central processors 15b-h perform calculations substantially simultaneously, far exceeding the speed of conventional processors. The method 100, which may be implemented by an instruction set to the processor nodes, informs the processor nodes how to divide the work and conduct the calculations. The method includes steps dividing the data into subsets 110 directing the subsets to predetermined nodes 115, performing the calculations 120 and outputting the results 125.

Abstract: A method and apparatus for performing complex mathematical calculations. The apparatus includes a multicore processor 10 where the cores 15 are connected 20 into a net with the processors on the periphery 15a primarily dedicated to input/output functions and distribution of tasks to the central processors 15b-h of the net. The central processors 15b-h perform calculations substantially simultaneously, far exceeding the speed of conventional processors. The method 100, which may be implemented by an instruction set to the processor nodes, informs the processor nodes how to divide the work and conduct the calculations. The method includes steps dividing the data into subsets 110 directing the subsets to predetermined nodes 115, performing the calculations 120 and outputting the results 125.

Abstract: A two-in-one wireless control kit is adapted to plug in a PCMCIA slot on a portable apparatus for storing and moving along with the portable apparatus and use at any time, and includes a transmitter and a receiver removably associated with each other to form one unit. The transmitter is provided at an upper side with related keys and at a lower side with at least a battery compartment for accommodating required batteries and a locating recess for receiving the receiver therein. The receiver includes a front connecting end for connecting to a related connecting port on the portable apparatus, and locating structures located at predetermined positions to removably engage the receiver with the locating recess below the transmitter, such that the associated transmitter and receiver can be plugged in the PCMCIA slot without projecting any part from the slot.

Abstract: A terminal seat includes a cable securing plate (30) and a cable conducting member (40). The cable securing plate (30) has a hole (31), a bend (33) formed on a free side thereof and extending toward the hole (31) and a sharp edge (32) formed on a side face defining the hole (31). The conducting member (40) has two legs (41) and an extension (42) extending oppositely relative to the two legs (41) and into the hole (31) of the cable securing plate (30) so that a cable extended into a gap between the extension (42) and the sharp edge (32) is able to be securely clamped therebetween.

Abstract: A terminal block includes a housing defining at least one bias compartment and at least one terminal compartment. A terminal plate is located within the housing and separates the bias compartment and the terminal compartment, and a bias element is positioned in the bias compartment. The bias element comprises a retainer portion extending through an opening in the terminal plate into the terminal compartment. The bias element is configured to retain a wire terminal to the terminal plate along a first direction and the terminal plate is configured to retain the wire terminal along a second direction when the wire terminal is received in through the retainer portion.

Abstract: An apparatus and method for detecting wireless local area network (WLAN) signals scans an area for radio-wave signals that meet IEEE802.11a, 802.11b, and 802.11g standards, and converts any detected radio-wave signal into a received signal strength indicator (RSSI) data, which is stored, recorded, and compared by a control unit with WLAN properties to determine whether there is a WLAN set up in the scanned area, or bearings and strength of any detected WLAN signal, making the detection highly discriminating and sensitive.

Abstract: A two-in-one wireless control kit is adapted to plug in a PCMCIA slot on a portable apparatus for storing and moving along with the portable apparatus and use at any time, and includes a transmitter and a receiver removably associated with each other to form one unit. The transmitter is provided at an upper side with related keys and at a lower side with at least a battery compartment for accommodating required batteries and a locating recess for receiving the receiver therein. The receiver includes a front connecting end for connecting to a related connecting port on the portable apparatus, and locating structures located at predetermined positions to removably engage the receiver with the locating recess below the transmitter, such that the associated transmitter and receiver can be plugged in the PCMCIA slot without projecting any part from the slot.