Abstract: An apparatus and method for indicating treatment site locations for phototherapy to the brain are disclosed. In some embodiments, the apparatus is a headpiece wearable by a patient. The headpiece includes a body adapted to be worn over at least a portion of the patient's scalp and a plurality of position indicators corresponding to a plurality of treatment site locations at the patient's scalp where a light source is to be sequentially positioned such that light from the light source is sequentially applied to irradiate at least a portion of the patient's brain. At least one of the position indicators includes an optically transmissive portion having an area of at least 1 cm2 through which the light propagates.

Abstract: The present invention provides a composition for strengthening glass. The composition may incorporate one or more of a surfactant, a silane, and an adhesive resin. The composition may further incorporate one or more of a water-based solvent, a defoamer, a glycerol, and an alcohol. A strengthened glass laminate may be formed of a glass base and a coating made up of the glass strengthening composition. The strengthened glass laminate may further comprise a film. The coating may adhere the film to the glass. A method for making a strengthened glass laminate may include providing a glass base and spraying the glass strengthening composition on the glass base. The present composition has the combined advantages of both optical clarity, high adhesion to glass, and dimensional stability.

Abstract: The present disclosure is directed toward systems and methods for providing third-party content to users of a social networking system. For example, the disclosed systems and methods receive content associated with an offer from a third party for presentation to a user, display the content associated with the offer in a graphical user interface including a feed of social networking content associated with the user, and detecting an interaction of the user with the displayed content associated with the offer. In response to the interaction of the user, the systems and methods navigate to a website associated with the third party and display a graphical element associated with the offer overlaying a portion of the website.

Abstract: Systems and methods for generating and validating certified electronic credentials are disclosed. A publisher may receive a certified electronic credential order from a credentialer and prepare a plurality of certified electronic credentials. The publisher may associate each credential with authentication information and a credential record, and retain a database of associated authentication information and credential records. The publisher may provide validation services, receiving a validation request through a credentialer's validation portal, and provide a response through the credentialer's portal indicative of the validity, additional information about the credential and/or the credential holder. The credential holder may assign a personal access key to control or limit the validation of a credential. A validating entity may receive credential validation through the credentialer with a heightened degree of confidence in the validation and lack of forgery.

Abstract: A blank for an enclosure for a recessed light fixture in an attic comprises a sheet of a thermally resistant material subdivided into a plurality of square panels by living hinges. The panels are foldable to provide a housing for the recessed light fixture. A package of blanks is constituted by a pair of such sheets, each sheet having a panel pivoted against an adjacent panel of same sheet in a back-to-back relationship when the sheets are juxtaposed relative to one another.

Abstract: A tampon applicator barrel includes an insertion tip at a forward end of the barrel, a main body section that extends from the insertion tip, and a reverse taper section that is joined to the main body section so that the main body section is between the insertion tip and the reverse taper section. The main body section tapers toward the insertion tip section. The reverse taper section tapers in a direction away from the insertion tip section. A finger grip section extends from the reverse taper section to a plunger receiving end of the barrel opposite the forward end. The barrel is straight from the forward end to the plunger receiving end that receives a plunger.

Abstract: Systems and methods for generating and validating certified electronic credentials are disclosed. A certified electronic credential may comprise a computer-readable file representative of a credential bestowed upon a recipient, in which the file is protected with one or more document integrity and document usage security feature. A publisher may receive a certified electronic credential order from a credentialer and prepare a plurality of certified electronic credentials. The publisher may associate each credential with authentication information and a credential record, and retain a database of associated authentication information and credential records. The publisher may provide validation services, receiving a validation request through a credentialer's validation portal, and provide a response through the credentialer's portal indicative of the validity, additional information about the credential, and even an audit trail.

Abstract: A polyaxial bone screw assembly includes a threaded shank body having an upper portion with a capture structure thereon, a retaining and articulating structure, a compression structure and a receiver for holding the capture structure, retaining and articulating structure, compression structure and a rod. The receiver includes arms that define a channel for receiving the rod. The arms have inner surfaces with a discontinuous flange form thereon for mating with a cooperating continuous flange form of a closure structure for capturing the rod within the receiver. The shank capture structure and the retaining and articulating structure are threadably attached and secured to one another with a buttress stop. In operation, the compression structure is disposed within the receiver between the shank upper portion and a rod but presses only upon the retaining and articulating structure.

Abstract: A method for treating a patient's heart is provided. The method includes providing a light source which emits light having an initial power density. The method further includes positioning the light source relative to the patient's heart with intervening tissue of the patient between the light source and the patient's heart. The method further includes directing light onto cardiac tissue of the patient's heart from the light source through the intervening tissue without damaging the intervening tissue. The cardiac tissue is irradiated by an efficacious power density of light for an efficacious period of time.

Abstract: A method for forming a self-healing ceramic matrix composite (CMC) component includes depositing a first self-healing particulate material in a first region of a CMC preform of the CMC component and depositing a second self-healing particulate material having a different chemical composition than the first self-healing particulate material in a second region of the CMC preform distinct from the first region.

Abstract: A casino game having a horse-racing theme. The casino game encompasses a number of playable races. A horseshoe playing surface is provided, which has a plurality of horse positions and a roulette-styled betting area inscribed thereon.

Abstract: A sterilization system includes a vial, a carrier of microorganisms disposed in the vial, and a fluid management system having an output connectable to the vial for delivering a liquid chemical sterilant and a neutralizer thereto. Additionally, a growth medium may be delivered to the vial such that the vial and growth medium may assessed for a change to a visual characteristic indicative of sterilization inefficacy.

Abstract: Disclosed is an advertisement product and method that allows a user of said product to create durable, weatherproof and professional signage and similar type product, more specifically advertisement signage. A single said advertisement product and related methods provide the user with several custom and/or standard signage creation options; whereby signs are created by printing predefined and in some cases customizable data group data to durable sign stock. Another disclosed and said advertisement product and method provides the user with an option of creating custom sized and printed labels for application to specific areas of related third party advertisement products, displays, apparatuses and signage, and in doing so creating a professional looking and legible advertisement display products. Further disclosed is a method and process by which system linked contact information as applied to said created advertisement products make available powerful system services to aid in advertising processes.

Abstract: A colorimetric sensor has a first material deposited on a surface, and sensing particles on a surface of the first material, wherein the sensing particles comprise sensing species dispersed into porous host structures, such that at least a portion of the sensing particles is exposed to an ambient environment, wherein the first material attaches the sensing particles to surface. A method of forming a colorimetric sensor including depositing a first material onto a substrate, providing porous sensing particles, wherein the sensing particles comprise sensing species dispersed into a porous host structure, and embedding the porous sensing particles onto a surface of the deposited first material, wherein the first material attaches the sensing particles to the substrate such that at least a portion of the sensing particles is exposed to an ambient environment.

Abstract: Provided herein are compositions and methods for generating alleles of genes of interest in plants. In some aspects, libraries of plants or seeds are provided that comprise an expression construct comprising a RNA-guided endonuclease (e.g., a Cas9 endonuclease) and multiple different guide RNAs that target regions of the gene of interest, such as regulatory regions.

Abstract: Embodiments relate to enabling a user of data-sharing applications executing on a computing device to indirectly exchange objects between the applications by adding objects from the applications to a journal application that manages a display area. The objects are displayed in the display area. The journal application collects metadata related to the objects and automatically curates lists of the objects according to the metadata. Curation of a list may involve moving objects into a list, merging objects, creating new objects out of content of existing objects, grouping objects according to a commonality thereof, etc. Machine learning services may be invoked to acquire additional metadata about the objects and to make curation decisions.

Abstract: The present application relates to materials and methods for exploiting synthetic lethality and/or chemo-sensitisation in DNA damage response (DDR) pathways. In particular, the application relates to ubiquitin hydrolase protein Ubiquitin Specific Protease 4 (USP4) and its association with DDR pathways. Further, the use of USP4 inhibitors in the treatment of cancer and methods of screening is described, in particular, use of inhibitors of USP4 in the treatment of tumours defective in double-strand break repair (DSBR) and/or tumours resistant to platinum-based chemotherapy, or to sensitise, i.e. chemosensitise or radiosensitise tumours to other therapeutic agents.

Abstract: A point-of-care hygiene compliance module includes a housing that is adapted to be attached to a dispensing container that dispenses material through a dispensing nozzle when actuated. The housing includes a pivoting actuation arm that is configured so as to be placed in operative contact with the dispensing nozzle. Thus, when the actuation arm is actuated, material is dispensed from the dispensing container, and a switch in operative contact with the actuation arm is actuated. The triggering of the switch updates a count value that is maintained by a controller, which may then be displayed or acquired by a remote computer to assess the amount of usage of the dispensing container.

Abstract: A system and method for treatment of thread includes a thread printer that applies colored coatings to thread. A camera is positioned to capture images of the treated thread after it passes through an outlet of the thread printer. The system processes the images to determine whether the location of a selected segment of the treated thread corresponds to an expected location. If the actual location of the selected segment corresponds to the expected location, the system will continue instructing the thread printer to selectively apply the colored coatings to the thread according to the pattern. However, if the actual location does not correspond to the expected location, the system will modify the pattern so that thread printer adjusts the size of one or more segment to automatically account for the misalignment.

Abstract: Methods, systems, and computer programs encoded on computer storage media, for binding service credentials to an application. One example system receives a service bind request for an application in a cloud application platform. The service bind request includes a request to bind a service provided by a service host in the cloud application platform. The service bind request specifies (i) an identifier for the service and (ii) a unique identifier for the application. The system receives, from the service host, credentials for the application to access the service. The system provides the credentials to a secure credential hub installed on the cloud application platform. The secure credential hub stores the credentials in association with a credential location identifier. The system grants, to the unique identifier for the application, read access to the credential location identifier. The system stores the credential location identifier as application metadata for the application.