Patents by Inventor Jacob Flagle

Jacob Flagle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190346471
    Abstract: A system for analysis of biopsy samples includes a tissue sample transport mechanism linking a biopsy sample excision tool to a tissue sample holder disposed in a staging area of an analysis unit. The tissue sample is automatically transported from the excision tool to the specimen holder, where the tissue sample is analyzed in the staging area of the analysis unit. The transport mechanism may include tubing and a vacuum source. The tissue sample holder may be configured to slow or temporarily stop a tissue sample for individual analysis, or collect multiple tissue samples for analysis as a group. A tissue sample sorting mechanism may be employed that allows separation of specimens that can be correlated to the analysis.
    Type: Application
    Filed: March 14, 2019
    Publication date: November 14, 2019
    Applicant: Hologic, Inc.
    Inventors: Jacob FLAGLE, Chia Yee Ang, Kenneth F. Defrietas, Ian Shaw, John Laviola, Samantha Perkins, Zachary R. Nicoson
  • Patent number: 10226256
    Abstract: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: March 12, 2019
    Assignees: Cook Medical Technologies LLC, Cook Biotech Incorporated
    Inventors: Brian C. Case, Jacob A. Flagle, Michael C. Hiles, Umesh H. Patel, F. Joseph Obermiller
  • Patent number: 10078093
    Abstract: A system for analysis of biopsy samples includes a tissue sample transport mechanism linking a biopsy sample excision tool to a tissue sample holder disposed in a staging area of an analysis unit. The tissue sample is automatically transported from the excision tool to the specimen holder, where the tissue sample is analyzed in the staging area of the analysis unit. The transport mechanism may include tubing and a vacuum source. The tissue sample holder may be configured to slow or temporarily stop a tissue sample for individual analysis, or collect multiple tissue samples for analysis as a group. A tissue sample sorting mechanism may be employed that allows separation of specimens that can be correlated to the analysis.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: September 18, 2018
    Assignee: HOLOGIC, INC.
    Inventors: Jacob Flagle, Chia Yee Ang, Kenneth F. Defrietas, Ian Shaw, John Laviola, Samantha Perkins, Zachary R. Nicoson
  • Patent number: 9980732
    Abstract: Described are devices, methods, and systems for achieving occlusion of vascular vessels. Further described are certain reduced or low profile procedures and devices for the percutaneous occlusion of the saphenous vein, such as in the treatment of a varicose vein condition caused by venous reflux.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: May 29, 2018
    Assignee: Cook Medical Technologies LLC
    Inventors: Ram H. Paul, Jr., Brian C. Case, Jacob A. Flagle
  • Patent number: 9895227
    Abstract: An expandable prosthesis having an imageable structure comprising one or more elements visually distinguishable by an external (e.g., radiographic or ultrasonic) imaging system, the structure being located about a first axis that corresponds to a structural feature of the prosthesis that is configured to perform a specific function particular to that axis. The imageable structure is configured to assist in the rotational orientation of the prosthesis during placement within the implantation site. In one embodiment, the prosthesis comprises a venous valve that includes imageable elements or structure, such as a pair of radiopaque markers, that defines the orifice of the valve structure such that the orifice can be oriented with a particular anatomical feature under imaging, such as to align the orifice with the long axis of the vessel.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: February 20, 2018
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Brian C. Case, Jacob A. Flagle, Michael L. Garrison, Andrew K. Hoffa, Ray Leonard, II
  • Publication number: 20170131311
    Abstract: A system for analysis of biopsy samples includes a tissue sample transport mechanism linking a biopsy sample excision tool to a tissue sample holder disposed in a staging area of an analysis unit. The tissue sample is automatically transported from the excision tool to the specimen holder, where the tissue sample is analyzed in the staging area of the analysis unit. The transport mechanism may include tubing and a vacuum source. The tissue sample holder may be configured to slow or temporarily stop a tissue sample for individual analysis, or collect multiple tissue samples for analysis as a group. A tissue sample sorting mechanism may be employed that allows separation of specimens that can be correlated to the analysis.
    Type: Application
    Filed: January 19, 2017
    Publication date: May 11, 2017
    Inventors: Jacob FLAGLE, Chia Yee ANG, Kenneth F. DEFRIETAS, Ian SHAW, John LAVIOLA, Samantha PERKINS, Zachary R. NICOSON
  • Patent number: 9492130
    Abstract: A system for analysis of biopsy samples includes a tissue sample transport mechanism linking a biopsy sample excision tool to a tissue sample holder disposed in a staging area of an analysis unit. The tissue sample is automatically transported from the excision tool to the specimen holder, where the tissue sample is analyzed in the staging area of the analysis unit. The transport mechanism may include tubing and a vacuum source. The tissue sample holder may be configured to slow or temporarily stop a tissue sample for individual analysis, or collect multiple tissue samples for analysis as a group. A tissue sample sorting mechanism may be employed that allows separation of specimens that can be correlated to the analysis.
    Type: Grant
    Filed: November 24, 2011
    Date of Patent: November 15, 2016
    Assignee: HOLOGIC, INC.
    Inventors: Jacob Flagle, Chia Yee Ang, Kenneth F. DeFreitas, Ian Shaw, John LaViola, Samantha Perkins, Zachary R. Nicoson
  • Patent number: 9421096
    Abstract: An expandable venous valve having a support structure that is configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame sections or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: August 23, 2016
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Brian C. Case, Michael L. Garrison, Andrew Hoffa, Darin G. Schaeffer, Jacob A. Flagle
  • Publication number: 20160213376
    Abstract: Described are devices, methods, and systems for achieving occlusion of vascular vessels. Further described are certain reduced or low profile procedures and devices for the percutaneous occlusion of the saphenous vein, such as in the treatment of a varicose vein condition caused by venous reflux.
    Type: Application
    Filed: April 1, 2016
    Publication date: July 28, 2016
    Inventors: Ram H. Paul, JR., Brian C. Case, Jacob A. Flagle
  • Patent number: 9326871
    Abstract: Implantable frames for use in body passages are provided herein. The implantable frames can include a plurality of hoop members joined by a plurality of longitudinal connecting members to form a tubular frame defining a cylindrical lumen. The plurality of longitudinal connecting members may include first and second longitudinal connecting members joining a first hoop member to a second hoop member such that the first and second longitudinal connecting members extend across an entire space separating the first and second hoop members.
    Type: Grant
    Filed: July 7, 2014
    Date of Patent: May 3, 2016
    Assignee: COOK MEDICAL TECHNOLOGIES LLC
    Inventors: Darin G. Schaeffer, Jacob A. Flagle, Michael L. Garrison, Brian C. Case, Andrew K. Hoffa
  • Patent number: 9307995
    Abstract: Described are devices, methods, and systems for achieving occlusion of vascular vessels. Further described are certain reduced or low profile procedures and devices for the percutaneous occlusion of the saphenous vein, such as in the treatment of a varicose vein condition caused by venous reflux. Devices and procedures can involve an endoluminal delivery device having an atraumatic distal end, that is advancable through a vascular vessel, and an occlusion device received on the endoluminal delivery device. The endoluminal delivery device can have one or more adaptations for releasably receiving the occlusion device. The occlusion device can include a sponge form material. The occlusion device can include a remodelable material or a synthetic material. The occlusion device can include an anchor.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: April 12, 2016
    Assignee: Cook Medical Technologies LLC
    Inventors: Ram H. Paul, Brian C. Case, Jacob A. Flagle
  • Patent number: 9078746
    Abstract: A valve prosthesis, such as an artificial venous valve, is described. The valve prosthesis has a support frame formed from a cannula and an attached covering that defines an opening adapted to move between a first position in which the opening is open to fluid flow and a second position in which the opening is closed to fluid flow. The support frame includes a leaflet support portion and a circumferential centering support element disposed adjacent the leaflet support portion with respect to a lengthwise axis of the support frame and mirroring the leaflet support portion with respect to a transverse axis of the support frame.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: July 14, 2015
    Assignees: COOK MEDICAL TECHNOLOGIES LLC, OREGON HEALTH AND SCIENCE UNIVERSITY
    Inventors: Dusan Pavcnik, Brian C. Case, Jacob A. Flagle, Michael Garrison, Andrew K. Hoffa, Raymond B. Leonard, II, Thomas A. Osborne, Ram H. Paul, Jr., Darin G. Schaeffer, Richard B Sisken
  • Patent number: 9017397
    Abstract: Prosthetic valve devices for implantation in body vessels are provided. The prosthetic valve device includes at least one flexible member that permits fluid flow in a first direction and substantially prevents fluid flow in a second. The valve device also includes an inflatable chamber at least partially attached to the flexible member. The inflatable chamber is adapted to receive inflating media and is adapted to contact the body vessel. A delivery system is also provided that includes a valve device and a delivery apparatus. The delivery apparatus includes a member adapted for filling the chamber of the valve device with inflating media. A related method of making the valve device is also provided.
    Type: Grant
    Filed: June 11, 2012
    Date of Patent: April 28, 2015
    Assignee: Cook Medical Technologies LLC
    Inventors: Thomas A. Osborne, Jacob A. Flagle, John A. Brumleve
  • Publication number: 20140379070
    Abstract: Implantable frames for use in body passages are provided herein. The implantable frames can include a plurality of hoop members joined by a plurality of longitudinal connecting members to form a tubular frame defining a cylindrical lumen. The plurality of longitudinal connecting members may include first and second longitudinal connecting members joining a first hoop member to a second hoop member such that the first and second longitudinal connecting members extend across an entire space separating the first and second hoop members.
    Type: Application
    Filed: July 7, 2014
    Publication date: December 25, 2014
    Inventors: Darin G. Schaeffer, Jacob A. Flagle, Michael L. Garrison, Brian C. Case, Andrew K. Hoffa
  • Patent number: 8858464
    Abstract: A surgical device is disclosed that comprises a cutting element, a biopsy line, a motor line, and a vacuum line. The cutting element includes an outer cannula and an inner cannula. The biopsy line is operatively connected to a control console for moving the inner cannula within the outer cannula to cut tissue cores. The motor line is operatively connected to the control console for operating the surgical device. The vacuum line is operatively connected to the inner cannula. A selectively openable tissue filter is operatively connected to the inner cannula, and is also connected to the vacuum line.
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: October 14, 2014
    Assignee: Suros Surgical Systems, Inc.
    Inventors: Michael Hoffa, Michael E. Miller, Joseph L. Mark, Jacob Flagle, Justin Smith, Jason M. Butcher
  • Patent number: 8834351
    Abstract: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: September 16, 2014
    Assignees: Cook Medical Technologies LLC, Cook Biotech Incorporated
    Inventors: Brian C. Case, Michael C. Hiles, Jacob A. Flagle, F. Joseph Obermiller, Umesh H. Patel
  • Publication number: 20140228933
    Abstract: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
    Type: Application
    Filed: February 4, 2014
    Publication date: August 14, 2014
    Inventors: Brian C. Case, Jacob A. Flagle
  • Patent number: 8771338
    Abstract: Implantable frames for use in body passages are provided herein. The implantable frames can include a plurality of hoop members joined by a plurality of longitudinal connecting members to form a tubular frame defining a cylindrical lumen. The plurality of longitudinal connecting members may include first and second longitudinal connecting members joining a first hoop member to a second hoop member such that the first and second longitudinal connecting members extend across an entire space separating the first and second hoop members.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: July 8, 2014
    Assignee: Cook Medical Technologies LLC
    Inventors: Darin G. Schaeffer, Jacob A. Flagle, Michael L. Garrison, Brian C. Case, Andrew K. Hoffa
  • Patent number: 8641776
    Abstract: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: February 4, 2014
    Assignees: Cook Biotech Incorporated, Cook Medical Technologies LLC
    Inventors: Brian C. Case, Michael C. Hiles, Jacob A. Flagle, F. Joseph Obermiller, Umesh H. Patel
  • Publication number: 20130331732
    Abstract: A surgical device is disclosed that comprises a cutting element, a biopsy line, a motor line, and a vacuum line. The cutting element includes an outer cannula and an inner cannula. The biopsy line is operatively connected to a control console for moving the inner cannula within the outer cannula to cut tissue cores. The motor line is operatively connected to the control console for operating the surgical device. The vacuum line is operatively connected to the inner cannula. A selectively openable tissue filter is operatively connected to the inner cannula, and is also connected to the vacuum line.
    Type: Application
    Filed: August 15, 2013
    Publication date: December 12, 2013
    Applicant: Suros Surgical Systems, Inc.
    Inventors: Michael Hoffa, Michael E. Miller, Joseph L. Mark, Jacob Flagle, Justin Smith, Jason M. Butcher