Patents by Inventor Jacob Flagle
Jacob Flagle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8641776Abstract: This invention relates in one aspect to the treatment of a vascular vessel with a biomaterial. The biomaterial can be a remodelable material that strengthens and/or supports the vessel walls. Additionally the biomaterial can include a variety of naturally occurring or added bioactive agents and/or viable cellular populations.Type: GrantFiled: March 15, 2011Date of Patent: February 4, 2014Assignees: Cook Biotech Incorporated, Cook Medical Technologies LLCInventors: Brian C. Case, Michael C. Hiles, Jacob A. Flagle, F. Joseph Obermiller, Umesh H. Patel
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Publication number: 20130331732Abstract: A surgical device is disclosed that comprises a cutting element, a biopsy line, a motor line, and a vacuum line. The cutting element includes an outer cannula and an inner cannula. The biopsy line is operatively connected to a control console for moving the inner cannula within the outer cannula to cut tissue cores. The motor line is operatively connected to the control console for operating the surgical device. The vacuum line is operatively connected to the inner cannula. A selectively openable tissue filter is operatively connected to the inner cannula, and is also connected to the vacuum line.Type: ApplicationFiled: August 15, 2013Publication date: December 12, 2013Applicant: Suros Surgical Systems, Inc.Inventors: Michael Hoffa, Michael E. Miller, Joseph L. Mark, Jacob Flagle, Justin Smith, Jason M. Butcher
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Publication number: 20130289706Abstract: Implantable frames for use in body passages are provided herein. The implantable frames can include a plurality of hoop members joined by a plurality of longitudinal connecting members to form a tubular frame defining a cylindrical lumen. The plurality of longitudinal connecting members may include first and second longitudinal connecting members joining a first hoop member to a second hoop member such that the first and second longitudinal connecting members extend across an entire space separating the first and second hoop members.Type: ApplicationFiled: June 24, 2013Publication date: October 31, 2013Inventors: Darin G. Schaeffer, Jacob A. Flagle, Michael L. Garrison, Brian C. Case, Andrew K. Hoffa
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Patent number: 8540760Abstract: Described are devices, methods, and systems useful for deploying one or more occlusive prostheses within the vasculature of a patient. Illustrative devices can include a deployment tube or sheath that contains an occlusive prosthesis, wherein a segment of the sheath is reversible by a user so as to deploy the prosthesis from the sheath lumen within a bodily lumen of a patient.Type: GrantFiled: June 30, 2008Date of Patent: September 24, 2013Assignee: Cook Medical Technologies LLCInventors: Ram H. Paul, Jr., Jacob A. Flagle, Brian C. Case
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Patent number: 8529468Abstract: A surgical device is disclosed that comprises a cutting element, a biopsy line, a motor line, and a vacuum line. The cutting element includes an outer cannula and an inner cannula. The biopsy line is operatively connected to a control console for moving the inner cannula within the outer cannula to cut tissue cores. The motor line is operatively connected to the control console for operating the surgical device. The vacuum line is operatively connected to the inner cannula. A selectively openable tissue filter is operatively connected to the inner cannula, and is also connected to the vacuum line.Type: GrantFiled: July 1, 2009Date of Patent: September 10, 2013Assignee: Suros Surgical Systems, Inc.Inventors: Michael Hoffa, Michael E. Miller, Joseph L. Mark, Jacob Flagle, Justin Smith, Jason M. Butcher
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Publication number: 20130231585Abstract: A system for analysis of biopsy samples includes a tissue sample transport mechanism linking a biopsy sample excision tool to a tissue sample holder disposed in a staging area of an analysis unit. The tissue sample is automatically transported from the excision tool to the specimen holder, where the tissue sample is analyzed in the staging area of the analysis unit. The transport mechanism may include tubing and a vacuum source. The tissue sample holder may be configured to slow or temporarily stop a tissue sample for individual analysis, or collect multiple tissue samples for analysis as a group. A tissue sample sorting mechanism may be employed that allows separation of specimens that can be correlated to the analysis.Type: ApplicationFiled: November 24, 2011Publication date: September 5, 2013Applicant: HOLOGIC INC.Inventors: Jacob Flagle, Chia Yee Ang, Kenneth F. DeFreitas, Ian Shaw, John LaViola, Samantha Perkins, Zachary R. Nicoson
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Publication number: 20130226291Abstract: A valve prosthesis, such as an artificial venous valve, is described. The valve prosthesis has a support frame formed from a cannula and an attached covering that defines an opening adapted to move between a first position in which the opening is open to fluid flow and a second position in which the opening is closed to fluid flow. The support frame includes a leaflet support portion and a circumferential centering support element disposed adjacent the leaflet support portion with respect to a lengthwise axis of the support frame and mirroring the leaflet support portion with respect to a transverse axis of the support frame.Type: ApplicationFiled: February 25, 2013Publication date: August 29, 2013Inventors: DUSAN PAVCNIK, BRIAN C. CASE, JACOB A. FLAGLE, MICHAEL GARRISON, ANDREW K. HOFFA, RAYMOND B. LEONARD, II, THOMAS A. OSBORNE, RAM H. PAUL, JR., DARIN G. SCHAEFFER, RICHARD B. SISKEN
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Patent number: 8518104Abstract: Described are methods, devices, and systems for occluding or ablating vascular vessels. Noninvasive procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous valve insufficiency. Further described is the cooperative use of an angiogenic remodelable material with one or more sclerosing agents to cause closure of a targeted bodily vessel.Type: GrantFiled: August 10, 2011Date of Patent: August 27, 2013Assignee: Cook Medical Technologies LLCInventors: Brian L. Bates, Ram H. Paul, Jacob A. Flagle
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Patent number: 8470020Abstract: Implantable frames for use in body passages are provided herein. The implantable frames can include a plurality of hoop members joined by a plurality of longitudinal connecting members to form a tubular frame defining a cylindrical lumen. The plurality of longitudinal connecting members may include first and second longitudinal connecting members joining a first hoop member to a second hoop member such that the first and second longitudinal connecting members extend across an entire space separating the first and second hoop members.Type: GrantFiled: April 16, 2012Date of Patent: June 25, 2013Assignee: Cook Medical Technologies LLCInventors: Darin G. Schaeffer, Jacob A. Flagle, Michael L. Garrison, Brian C. Case, Andrew K. Hoffa
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Patent number: 8444666Abstract: A filter may have an apical hub and a plurality of divergent legs. A first attachment member may be separate from, but attached to the second end of at least one of the plurality of divergent legs. A second attachment member may be separate from, but attached to a stent. The first and second attachment members may be separate from, but attachable to one another to releasably attach the filter to the stent. One of the first attachment member and the second attachment member may include an attachment wire that is positioned in a lumen of a tubular member or one of the first attachment member and the second attachment member may comprise a cannula. In some implementations, an upward motion applied to the retrieval connection member may disengage at least one attachment wire of the first attachment member from the second attachment member.Type: GrantFiled: September 12, 2003Date of Patent: May 21, 2013Assignee: Cook Medical Technologies LLCInventors: Dusan Pavcnik, Brian C. Case, John A. Kaufman, Michael L. Garrison, Jacob A. Flagle
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Patent number: 8430827Abstract: A biopsy device having a stylet, an outer cannula, and a vacuum chamber is disclosed. The stylet includes a lumen with an open proximal end and a tissue receiving opening near a distal end thereof. The outer cannula is slidably disposed over the stylet and has an open distal end with a cutting edge formed thereon. The vacuum chamber is in communication with the lumen of the stylet. Actuation of the outer cannula causes a vacuum to be delivered to the tissue receiving opening through the lumen of the stylet before the outer cannula advances distally.Type: GrantFiled: September 23, 2011Date of Patent: April 30, 2013Assignee: Suros Surgical Sysytems, Inc.Inventors: Zachary R. Nicoson, Jacob Flagle, Michael E. Miller, Joseph L. Mark
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Patent number: 8398663Abstract: Valvulotome devices and methods are provided. Valvulotome devices include one or more valvulotome arms that have a u-shaped curved body with opposing arms and a base portion that extends between the arms. The valvulotome arm defines a notch open at one end on one of the arms and extending into the base portion of the u-shaped curved body. The notch defines an angled surface that provides a cutting edge. Methods of making valvulotome devices are also described.Type: GrantFiled: May 17, 2010Date of Patent: March 19, 2013Assignee: Cook Medical Technologies LLCInventors: Ram H. Paul, Jr., Brian C. Case, Jacob A. Flagle
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Patent number: 8382822Abstract: A valve prosthesis, such as an artificial venous valve, having a support frame and leaf structure comprising one or more leaflets in which the outer edge of each leaflet engages the inner circumference of the bodily passageway along a serpentine path urged against the passageway by an expandable frame, while the inner edges move in response to fluid to restrict retrograde flow. Optionally, one or more elements can extend from the support frame/leaf structure to provide centering support and/or protection from the leaflet adhering to the vessel wall. In one embodiment, the centering support structure comprises a second or third expandable frames attached to and extending from the proximal and/or distal ends of main valve structure and support frame. In another embodiment, one or more support elements extend outward from the valve support frame to engage the vessel wall to provide greater longitudinal stability.Type: GrantFiled: October 7, 2009Date of Patent: February 26, 2013Assignees: Cook Medical Technologies LLC, Oregon Health & Science UniversityInventors: Dusan Pavcnik, Brian C. Case, Jacob A. Flagle, Michael Garrison, Andrew K. Hoffa, Raymond B. Leonard, II, Thomas A. Osborne, Ram H. Paul, Jr., Darin G. Schaeffer, Richard B Sisken
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Publication number: 20130018453Abstract: An expandable venous valve having a support structure that is configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame sections or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure.Type: ApplicationFiled: July 16, 2012Publication date: January 17, 2013Inventors: Brian C. Case, Michael L. Garrison, Andrew Hoffa, Darin G. Schaeffer, Jacob A. Flagle
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Publication number: 20120253450Abstract: An expandable prosthesis having an imageable structure comprising one or more elements visually distinguishable by an external (e.g., radiographic or ultrasonic) imaging system, the structure being located about a first axis that corresponds to a structural feature of the prosthesis that is configured to perform a specific function particular to that axis. The imageable structure is configured to assist in the rotational orientation of the prosthesis during placement within the implantation site. In one embodiment, the prosthesis comprises a venous valve that includes imageable elements or structure, such as a pair of radiopaque markers, that defines the orifice of the valve structure such that the orifice can be oriented with a particular anatomical feature under imaging, such as to align the orifice with the long axis of the vessel.Type: ApplicationFiled: April 11, 2012Publication date: October 4, 2012Applicant: COOK MEDICAL TECHNOLOGIES LLCInventors: Brian C. Case, Jacob A. Flagle, Michael L. Garrison, Andrew K. Hoffa, Ray Leonard, II
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Publication number: 20120253446Abstract: Prosthetic valve devices for implantation in body vessels are provided. The prosthetic valve device includes at least one flexible member that permits fluid flow in a first direction and substantially prevents fluid flow in a second. The valve device also includes an inflatable chamber at least partially attached to the flexible member. The inflatable chamber is adapted to receive inflating media and is adapted to contact the body vessel. A delivery system is also provided that includes a valve device and a delivery apparatus. The delivery apparatus includes a member adapted for filling the chamber of the valve device with inflating media. A related method of making the valve device is also provided.Type: ApplicationFiled: June 11, 2012Publication date: October 4, 2012Inventors: Thomas A. Osborne, Jacob A. Flagle, John A. Brumleve
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Publication number: 20120203327Abstract: Implantable frames for use in body passages are provided herein. The implantable frames can include a plurality of hoop members joined by a plurality of longitudinal connecting members to form a tubular frame defining a cylindrical lumen. The plurality of longitudinal connecting members may include first and second longitudinal connecting members joining a first hoop member to a second hoop member such that the first and second longitudinal connecting members extend across an entire space separating the first and second hoop members.Type: ApplicationFiled: April 16, 2012Publication date: August 9, 2012Applicant: COOK MEDICAL TECHNOLOGIES LLCInventors: Brian C. Case, Jacob A. Flagle, Andrew K. Hoffa, Darin G. Schaeffer, Michael L. Garrison
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Patent number: 8221492Abstract: An expandable venous valve having a support structure that configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure.Type: GrantFiled: April 21, 2004Date of Patent: July 17, 2012Assignee: Cook Medical TechnologiesInventors: Brian C. Case, Michael L. Garrison, Andrew Hoffa, Darin G. Schaeffer, Jacob A. Flagle
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Patent number: 8197534Abstract: Prosthetic valve devices for implantation in body vessels are provided. The prosthetic valve device includes at least one flexible member that permits fluid flow in a first direction and substantially prevents fluid flow in a second. The valve device also includes an inflatable chamber at least partially attached to the flexible member. The inflatable chamber is adapted to receive inflating media and is adapted to contact the body vessel. A delivery system is also provided that includes a valve device and a delivery apparatus. The delivery apparatus includes a member adapted for filling the chamber of the valve device with inflating media. A related method of making the valve device is also provided.Type: GrantFiled: March 30, 2006Date of Patent: June 12, 2012Assignee: Cook Medical Technologies LLCInventors: Thomas A. Osborne, Jacob A. Flagle, John A. Brumleve
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Patent number: 8177837Abstract: Described are percutaneous vascular valves free of attached support structures and deployment systems and methods for providing attachment of the valves within a vascular vessel.Type: GrantFiled: January 18, 2011Date of Patent: May 15, 2012Assignee: Cook Medical Technologies LLCInventors: Brian C. Case, Charles W. Agnew, Jacob A. Flagle