Abstract: Systems, devices and methods for modulation of sirtuins by neurostimulation. In particular, sirtuins may be modulated by stimulation of the vagus nerve. Further described herein generally are methods, systems and devices, for specifically modulating sirtuins, including sub-sets (types or localized regions) of sirtuins by vagus nerve stimulation (VNS).

Abstract: Described herein are methods and systems for applying extremely low duty-cycle stimulation sufficient to treat chronic inflammation. In particular, described herein are single supra-threshold pulses of electrical stimulation sufficient to result in a long-lasting (e.g., >4 hours, greater than 12 hours, greater than 24 hours, greater than 48 hours) inhibition of pro-inflammatory cytokines and/or effects of chronic inflammation. These methods and devices are particularly of interest in treatment of inflammatory bowel disease (IBD).

Abstract: Methods and devices for the treatment of chronic pain by modulation of the cholinergic anti-inflammatory pathway. In particular, the methods and systems described herein may be used to enhance chronic pain therapies such as spinal cord stimulation (SCS). Thus, the present invention describes devices and methods for modulation of the cytokine pathway by stimulation of the neuronal cholinergic anti-inflammatory pathway (NCAP) to enhance the treatment of chronic pain by SCS. The use of NCAP in conjunction with SCS may potentiate the effects of SCS and/or prevent the desensitization of the patient to SCS.

Abstract: A diagnostic tool for speech recognition applications is provided, which enables a administrator to collect multiple recorded speech sessions. The administrator can then search for various failure points common to one or more of the recorded sessions in order to get a list of all sessions that have the same failure points. The invention allows the administrator to playback the session or replay any portion of the session to see the flow of the application and the recorded utterances. The invention provides the administrator with information about how to maximize the efficiency of the application which enables the administrator to edit the application to avoid future failure points.

Abstract: The present invention provides an interactive telephony interface for a user via a telephony terminal. Upon initiating an interaction with the telephony terminal, a session is provided between the telephony terminal and an interactive control system (ICS), which is capable of responding to commands for requested services from the user and initiating those services. The services can range from initiating a telephone call from the telephony terminal to requesting retrieval of information or triggering any number of actions. The provision of such services may be initiated by accessing service logic from within the ICS or within remote servers accessible by the ICS. The user may request multiple services at any given time, and the ICS will respond by initiating the services during a single telephony interaction. The ICS is also capable of providing unsolicited information, such as advertisements, to the user while waiting for the requested services to be provided.

Abstract: Call-protect systems are arranged, upon an operating failure, to handoff a call in progress and maintain processing of the call without disruption or need to reinitiate. Application processor (AP) nodes are configured to continuously run standby call processing (CP) facilities, in addition to running active call processing facilities engaged in current call processing. As a call is actively processed, call context information, such as caller and account identification and call status, is stored in memory within a call processing subsystem. Upon a failure affecting the AP node processing a call, call handoff is made to the standby CP facility of a different AP node. The capability of maintaining processing of the handoff call without disruption is enhanced by retrieval of the stored call context information for that call.

Abstract: Supported bis-cyclopentadienyl chromium [II] catalysts are modified with compounds having in their structure the moiety ##STR1## in order to improve the toughness and impact strength of the resulting ethylene polymers made therewith.

Abstract: Ethylene polymerization catalysts are prepared by depositing a chromocene compound on a support with a titanium compound and activating the final blend at 300.degree. C. to about 1000.degree. C. A fluoriding agent can be optionally added where a narrower molecular weight distribution of the polyethylene to be obtained is desired. Catalysts with good reproducibility, when prepared by this method, show particular utility in production of polyethylene by a fluid bed process.

Abstract: A catalyst for the preparation of ethylene polymers having higher melt indexes comprises a silyl chromate deposited on a silica support containing both aluminum and titanium.