Patents by Inventor Jacob Mathew

Jacob Mathew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stereospecific synthesis of tetrasubstituted acrylic esters
    Patent number: 5162566
    Abstract: Substantially stereospacific (E)-tetrasubstituted acrylic esters, such as ##STR1## where R is hydrogen alkyl, R.sub.1 is alkyl, aryl or aralkyl, R.sub.2 and R.sub.4 are alkyl, are formed from racemic mixtures of corresponding unsaturated esters and cuprates of the formula (R.sub.3).sub.2 CuX, wherein R.sub.3 is alkyl, aryl or aralkyl, and X is lithium or magnesium halide.
    Type: Grant
    Filed: August 26, 1991
    Date of Patent: November 10, 1992
    Assignee: Mallinckrodt Specialty Chemicals Company
    Inventor: Jacob Mathew
  • Stereospecific synthesis of 2(R)-2-methyl-3-dimethylamino-propiophenone (d-DAMP)
    Patent number: 5132457
    Abstract: In a method for producing 2(R)-2-methyl-3-dimethylamino-propiophenone (d-DAMP), a chiral ester of the formula ##STR1## wherein R is an alkyl of from 1 to about 5 carbon atoms, is provided. The chiral easter of formula (I) is converted into a chiral amino-alcohol of the formula ##STR2## and the chiral amino-alcohol is oxidized so as to form d-DAMP.
    Type: Grant
    Filed: August 26, 1991
    Date of Patent: July 21, 1992
    Assignee: Mallinckrodt Specialty Chemicals Company
    Inventor: Jacob Mathew
  • Alkyl-2-thiosubstituted-3-substituted-2-butenoates and their synthesis
    Patent number: 5089611
    Abstract: An alkyl 2-thiosubstituted-3-substituted-2-butenoate ##STR1## is prepared by reacting an alkyl 2-chloro-3-substituted-3-butenoate with a thio compound under phase transfer conditions.
    Type: Grant
    Filed: March 12, 1990
    Date of Patent: February 18, 1992
    Assignee: Petrolite Corporation
    Inventor: Jacob Mathew
  • Synthesis of 2,3,5-trisubstituted-2-cyclopentenones via base induced cyclization of alpha-chloro unsaturated ketones
    Patent number: 5026918
    Abstract: 2,3,5-trisubstituted-2-cyclopentenones or 2,3-disubstituted-2-cyclopentenones (such as cis-jasmone) are prepared by contacting a 3-chloro-3,4-disubstituted-4-pentene-2-one with a strong base. Methods of preparing the reactants are also disclosed.
    Type: Grant
    Filed: April 27, 1990
    Date of Patent: June 25, 1991
    Assignee: Petrolite Corporation
    Inventor: Jacob Mathew
  • Synthesis of 2,3-disubstituted-2-cyclopentenones via lithiomethylmercapto compounds
    Patent number: 5023382
    Abstract: 2,3-disubstituted-2-cyclopenenones (such as cisjasmone) are prepared by (a) reacting an alkl 2-chloro-2,3-disubstituted-3-butenoate with a lithiomercaptan compound, (b) subjecting that product to reductive dehydrosulfurization. Methods of preparing the reactants are also disclosed.
    Type: Grant
    Filed: January 24, 1990
    Date of Patent: June 11, 1991
    Assignee: Petrolite Corporation
    Inventor: Jacob Mathew
  • Synthesis of N,3,4-trisubstituted-3-azoline-2-ones
    Patent number: 5021587
    Abstract: N,3,4-trisubstituted-3-azoline-2-ones (such as N-benzyl-3,4-dimethyl-3-azoline-2-one) are prepared by the reaction of an alkyl 2-chloro-2,3-disubstituted-3-butenoate (such as ethyl 2-chloro-2,3-dimethyl-3-butenoate) with a primary amine (such as benzyl amine). Methods for preparing the precursor esters are also disclosed.
    Type: Grant
    Filed: January 24, 1990
    Date of Patent: June 4, 1991
    Assignee: Petrolite Corporation
    Inventor: Jacob Mathew
  • Alkaline dishwasher detergent
    Patent number: 4259199
    Abstract: Alkaline dishwasher detergent composition having a specific critical pH; relatively high levels of bleach, reserve alkalinity and surfactant; and, preferably, a specific mixture of alkali metal silicates. The detergent composition is substantially free of highly alkaline materials and organic builders.
    Type: Grant
    Filed: September 18, 1979
    Date of Patent: March 31, 1981
    Assignee: The Procter & Gamble Company
    Inventors: Maria Luz S. Wee, Lawrence A. Gilbert, Jacob Mathew