Abstract: A light emitting module including a substrate having an insulating region and including a conductive pattern, a light source disposed on an upper surface of the substrate and electrically connected to the conductive pattern, a lens including a lower surface, a light incident region, a light exit surface, a leg protruding from the lower surface of the lens, and an adhesion material coupling the leg to the upper surface of the substrate, in which the light incident region has a central axis, the light incident region includes a protrusion facet, the protrusion facet having a first end and a second end opposite to the first end, and the protrusion facet is protruded toward the central axis with respect to an imaginary linear line connecting the first end and the second end of the protrusion facet.

Abstract: A lens for dispersing light emitted from a light emitting device, the lens including a lower surface, a light incident portion having a concave shape from the lower surface, the light incident portion having a light incident surface, and a light exit portion through which light having entered the lens through the light incident portion exits the lens to an outside of the lens, in which the light incident surface includes at least one protruding light incident facet.

Abstract: A lens including a light entering part having a concave shape in a lower region of the lens, and on which light emitted from a light emitting device is to be incident, and a light exiting part through which the incident light is emitted to an outside of the lens, in which each of the light entering part and the light exiting part has a major axis and a minor axis in plan view, and the major axis of the light entering part is orthogonal to the major axis of the light exiting part, the light entering part includes a light incident vertical surface extending from a lower surface of the lens, and a light incident inclined surface extending upward from the light incident vertical surface, and the light incident vertical surface surrounds the light emitting device.

Abstract: A lens including a light entering part having a concave shape in a lower region of the lens, and on which light emitted from a light emitting device is to be incident, and a light exiting part through which the incident light is emitted to an outside of the lens, in which each of the light entering part and the light exiting part has a major axis and a minor axis in plan view, and the major axis of the light entering part is orthogonal to the major axis of the light exiting part, the light entering part includes a light incident vertical surface extending from a lower surface of the lens, and a light incident inclined surface extending upward from the light incident vertical surface, and the light incident vertical surface surrounds the light emitting device.

Abstract: Mechanisms are provided to implement a privacy enhanced location service for determining a granularity of location information to return to a requestor computing device. The privacy enhanced location service receives, from a requestor computing device, a location query requesting location information for a subject. The privacy enhanced location service retrieves a selected subject privacy policy data structure, selected from a set of subject privacy policy data structures corresponding to the subject identified in the location query. The privacy enhanced location service applies the selected subject privacy policy data structure to location information associated with the subject to generate modified location information having a granularity of location information specified in the selected subject privacy policy data structure. The privacy enhanced location service transmits the modified location information to the requestor computing device.

Abstract: Techniques regarding generating an ensemble of quantum kernel-based learners for one or more quantum machine learning models are provided. For example, one or more embodiments described herein can comprise a system, which can comprise a memory that can store computer executable components. The system can also comprise a processor, operably coupled to the memory, and that can execute the computer executable components stored in the memory. The computer executable components can comprise an ensemble component that can generate an ensemble of quantum kernel-based learners by selecting a quantum kernel at multiple iterations of a boosting procedure that analyzes a range of feature maps employable by a quantum machine learning model.

Abstract: A light emitting module including a substrate, a light emitting device disposed on the substrate, and a lens disposed above the light emitting device to disperse light, the lens including a light incident portion through which light emitted from the light emitting device enters the lens and a light exit portion through which the light exits the lens, in which each of the light incident portion and the light exit portion has a major axis and a minor axis in plan view, the major axis of the light incident portion is disposed at a right angle with respect to the major axis of the light exit portion, the lens includes a plurality of legs formed on a lower surface of the lens to support the lens, and at least one of the legs includes a leg protrusion protruding downwards from a lower surface thereof.

Abstract: Provided are an anti-B7-H3 antibody binding specifically to B7-H3 and a use thereof and, more particularly, are an anti-B7-H3 antibody or an antigen binding fragment thereof, a nucleic acid encoding the same, a vector carrying the nucleic acid, a cell transformed with the vector, a method for preparing the same, an antibody-drug conjugate or a multi-specific antibody comprising the same, and a pharmaceutical composition for preventing or treating cancer, autoimmune disease, or inflammatory disease, or a diagnostic composition, each composition comprising the same. The anti-B7-H3 antibody or antigen binding fragment thereof can bind to human and non-human B7-H3 at high affinity and can be endocytosized after binding thereto. Thus, the anti-B7-H3 antibody or antigen binding fragment thereof, or the antibody-drug conjugate or the multi-specific antibody comprising the same can be advantageously used for preventing, treating, or diagnosing cancer or tumor, autoimmune disease, or inflammatory disease.

Abstract: The present invention relates to new antibody-drug conjugates (ADCs) targeting DLK1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of diseases, more specifically, uses for such ADCs in producing drugs for treatment and/or prevention of proliferative and/or angiogenetic diseases, for example, cancer. More particularly, the present invention relates to an antibody-drug conjugate comprising an antibody binding with DLK1 or an antigen-binding fragment thereof, and a pharmaceutical composition comprising the same.

Abstract: New anti-VSIG4 (V-set Ig domain-containing 4) antibodies or an antigen-binding fragments are disclosed. Uses of these antibodies, including methods of treatment, are also provided.

Abstract: A lens for dispersing light emitted from a light emitting device, the lens including a lower surface, a light incident portion having a concave shape from the lower surface, the light incident portion having a light incident surface, and a light exit portion through which light having entered the lens through the light incident portion exits the lens to an outside of the lens, in which the light incident surface includes at least one protruding light incident facet.

Abstract: Embodiments herein describe a return network simulation system that can simulate changes in a retailer's return network to determine the impact of those changes. Advantageously, being able to accurately simulate the retailer's return network means changes can be evaluated without first making those adjustments in the physical return network. Doing so avoids the cost of implementing the changes on the return network without first being able to predict whether the changes will have a net positive result (e.g., a positive result that offsets any negative results). A retailer can first simulate the change on the return network, review how the change affects one or more KPIs, and then decide whether to implement the change in the actual return network. As a result, the retailer has a reliable indicator whether the changes will result in a desired effect.

Abstract: The present invention relates to an antibody against delta-like 1 homolog (Drosophila) (DLK1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector comprising the nucleic acid, a cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, an antibody drug conjugate (ADC) comprising the same, a pharmaceutical composition for treating cancer, a composition for diagnosing cancer, and a chimeric antigen receptor (CAR) and a T-cell engager comprising the same.

Abstract: A lens including a light entering part having a concave shape in a lower region of the lens, and on which light emitted from a light emitting device is to be incident, and a light exiting part through which the incident light is emitted to an outside of the lens, in which each of the light entering part and the light exiting part has a major axis and a minor axis in plan view, and the major axis of the light entering part is orthogonal to the major axis of the light exiting part, the light entering part includes a light incident vertical surface extending from a lower surface of the lens, and a light incident inclined surface extending upward from the light incident vertical surface, and the light incident vertical surface surrounds the light emitting device.

Abstract: The present disclosure relates to antibody-drug conjugates (ADCs) wherein one or more active agents are conjugated to an anti-B7-H3 antibody through a linker. The linker may comprise a unit that covalently links active agents to the antibody. The disclosure further relates to monoclonal antibodies and antigen binding fragments, variants, multimeric versions, or bispecifics thereof that specifically bind B7-H3, as well as methods of making and using these anti-B7-H3 antibodies and antigen-binding fragments thereof in a variety of therapeutic, diagnostic and prophylactic indications.

Abstract: Disclosed are an antibody to human programmed cell death 1 (PD-1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector including the nucleic acid, an isolated cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, and a composition for preventing or treating cancer containing the same. The novel antibody binding to PD-1 or an antigen-binding fragment thereof can bind to PD-1 and inhibit the activity of PD-1, thus being useful for the development of immunotherapeutic agents for various diseases associated with PD-1.

Abstract: A lens including a light entering part having a concave shape in a lower region of the lens, and on which light emitted from a light emitting device is to be incident, and a light exiting part through which the incident light is emitted to the outside, in which each of the light entering part and the light exiting part has a major axis and a minor axis in plan view, and the major axis of the light entering part is orthogonal to the major axis of the light exiting part, and the light entering part includes a light incident vertical surface extending from a lower surface of the lens and a light incident inclined surface extending upward from the light incident vertical surface.

Abstract: A computer-implemented method for a machine learning based design framework includes receiving input data, generating a design proposal based on the input data using a machine learning model, receiving feedback for the design proposal from a designated reviewer of the design proposal, updating a user preference profile associated with the designated reviewer using data generated by a different machine learning model based on the feedback for the design proposal, updating the design proposal to replace the candidate design with a new candidate design based on the user preference profile, and generating a final design based on the design proposal. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Techniques for a machine learning based tiered graphical user interface (GUI) are described herein. Aspects of the invention include receiving a set of offered products. The set of offered products is sorted into a plurality of tiers, and an initial tiered GUI is generated based on the sorting. Based on receiving customer feedback via the tiered GUI, the sorting of the set of offered products into the plurality of tiers is updated, and an updated tiered GUI is generated based on the updated sorting.

Abstract: A hypergraph is constructed based on historical shopping cart data. A node of the hypergraph corresponds to a shopping basket, and a hyperedge of the hypergraph corresponds to a unique product, the hyperedge connecting all nodes of the hypergraph representing baskets containing the unique product. A hypergraph partition algorithm identifies a cluster of shopping baskets represented in the hypergraph and determined to be similar to a given basket. Based on the cluster of shopping baskets a dual-level return prediction is performed. The dual-level return prediction includes predicting whether the given basket will be returned, and based on predicting that the given basket will be returned, predicting a probability that a product in the given basket will be returned. Based on predicting that the given basket will be returned, an ameliorative action is performed to reduce the probability.