Patents by Inventor Jagadish C. Sircar

Jagadish C. Sircar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-substituted-2-hydroxy-.alpha.-oxo-benzeneacetamides and pharmaceutical compositions having activity as modulators of the arachidonic acid cascade
    Patent number: 4939133
    Abstract: The present invention relates to novel N-substituted 2-hydroxybenzamide and N-substituted 2-hydroxy-.alpha.-oxo-benezene acetamide compounds pharmaceutical compositions, and methods of use for therefore for the treatment of diseases in which products having lipoxygenase enzyme activity contribute to the pathological condition. Selected novel intermediates are also the present invention.
    Type: Grant
    Filed: October 1, 1985
    Date of Patent: July 3, 1990
    Assignee: Warner-Lambert Company
    Inventors: David T. Connor, Daniel L. Flynn, Wiaczeslaw A. Cetenko, Jagadish C. Sircar, Charles F. Schwender, Elizabeth A. Johnson, Roderick J. Sorenson, Paul C. Unangst
  • Analogues of pyrrolo[3,2d]pyrimidin-4-ones
    Patent number: 4923872
    Abstract: The present invention is novel derivatives of pyrrolo[3,2-d]pyrimidines and pharmaceutical compositions and methods of use therefor. The derivatives are inhibitors of purine nucleoside phosphorylase selectively cytotoxic to T-cells but not to B-cells in the presence of 2'-deoxyguanosine and, therefore, are for use in the treatment of autoimmune diseases, gout, psoriasis or rejection of transplantation.
    Type: Grant
    Filed: April 10, 1989
    Date of Patent: May 8, 1990
    Assignee: Warner-Lambert Co.
    Inventors: Catherine R. Kostlan, Jagadish C. Sircar
  • 7-deazaguanines as immunomodulators
    Patent number: 4921858
    Abstract: The present invention is various 7-deazaguanines having activity as immunomodulators. Also included are pharmaceutical compositions and methods of use thereof.
    Type: Grant
    Filed: March 13, 1989
    Date of Patent: May 1, 1990
    Assignee: Warner-Lambert Company
    Inventors: Thomas C. Malone, Jagadish C. Sircar
  • Purine derivatives
    Patent number: 4921859
    Abstract: Novel purine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions as well as novel intermediates in the manufacture thereof.
    Type: Grant
    Filed: September 29, 1988
    Date of Patent: May 1, 1990
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Charles F. Schwender, Mark J. Suto
  • Enolamides, pharmaceutical compositions and methods of use thereof for treating inflammation
    Patent number: 4921871
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: November 16, 1987
    Date of Patent: May 1, 1990
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Glycerine derivatives
    Patent number: 4918219
    Abstract: Novel purine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions as well as novel intermediates in the manufacture thereof.
    Type: Grant
    Filed: September 29, 1989
    Date of Patent: April 17, 1990
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Charles F. Schwender, Mark J. Suto
  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4874758
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and method of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 4, 1988
    Date of Patent: October 17, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Centenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Process for preparing guanine derivatives
    Patent number: 4874862
    Abstract: Novel guanine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions thereof.
    Type: Grant
    Filed: October 14, 1987
    Date of Patent: October 17, 1989
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Catherine R. Brungardt, Charles F. Schwender
  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868195
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 7, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868200
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 9, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868199
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 9, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868205
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 11, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Purine derivatives
    Patent number: 4806642
    Abstract: Novel purine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions as well as novel intermediates in the manufacture thereof.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: February 21, 1989
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Charles F. Schwender, Mark J. Suto
  • Purine derivatives
    Patent number: 4772606
    Abstract: Novel purine derivatives, particularly novel guanines and hypoxanthines, are described as agents for treating autoimmune diseases. Also novel methods of manufacture for the derivatives, pharmaceutical compositions thereof, and methods of use therefor are the invention.
    Type: Grant
    Filed: August 22, 1985
    Date of Patent: September 20, 1988
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Garry W. Pinter
  • Enolamides, pharmaceutical compositions and methods for treating inflammation
    Patent number: 4761424
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: October 1, 1985
    Date of Patent: August 2, 1988
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Guanine derivatives
    Patent number: 4748177
    Abstract: Novel guanine derivatives are described as agents for treating autoimmune diseases as well as a method of manufacture and pharmaceutical compositions thereof.
    Type: Grant
    Filed: February 11, 1985
    Date of Patent: May 31, 1988
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Catherine R. Brungardt, Charles F. Schwender
  • 5-substituted-3-aminoisoxazole compounds
    Patent number: 4581458
    Abstract: 4-Hydroxy-N-[5-[(substituted hetero)methyl]-3-isoxazolyl]-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides as agents for treating pain in mammals resulting from inflammation.
    Type: Grant
    Filed: October 12, 1984
    Date of Patent: April 8, 1986
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Thomas Capiris
  • 3-Isoxa-zolyl-2H-1,2-benzothiazine-3-carboxamide, 1,1-dioxides
    Patent number: 4489077
    Abstract: 4-Hydroxy-N-[5-[(substituted hetero)methyl]-3-isoxazolyl]-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides as agents for treating pain in mammals resulting from inflammation.
    Type: Grant
    Filed: February 2, 1984
    Date of Patent: December 18, 1984
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Thomas Capiris
  • 4-Alkyl-pyrazolo[5,1-b]-quinazolin-9(4H)-ones and anti-allergic compositions containing them
    Patent number: 4261997
    Abstract: Certain pyrazolo[5,1-b]quinazolin-9(4H)-ones are disclosed. These compounds prevent the allergic response in mammals.
    Type: Grant
    Filed: January 11, 1980
    Date of Patent: April 14, 1981
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Stephen J. Kesten
  • Pyrazolo[5,1-b]quinazolin-9-(4H)-ones and anti-allergic pharmaceutical compositions containing them
    Patent number: 4261996
    Abstract: Certain pyrazolo[5,1-b]quinazolin-9-(4H)-ones are disclosed. These compounds prevent the allergic response in mammals. Novel alkylthioanthranilic acids, useful as intermediates, are also disclosed.
    Type: Grant
    Filed: January 11, 1980
    Date of Patent: April 14, 1981
    Assignee: Warner-Lambert Company
    Inventors: Jagadish C. Sircar, Thomas Capiris