Abstract: Disclosed are novel gene therapy constructs containing both HEXA and HEXB genes to treat GM2 gangliosidoses, including Sandhoff disease and Tay-Sach's disease. Also described are co-treatments using chaperone and anti-inflammatory agents to enhance the effects of gene therapy.

Abstract: Provided herein are detect-free solid-state separators which are useful as Li| ion-conducting electrolytes in electro-chemical cells and devices, such as, but not limited to, rechargeable batteries. In some examples, the separators have a Li+ ion-conductivity greater than 1*10?3 S/cm at room temperature.

Abstract: A target communications device receiving from a source communications device a notification that a user communications device is to be handed over from that source communications device, provides the source communications device with multiple component carrier information for use by the user communications device. The multiple component carrier information includes information indicating to the user communications device which of the multiple component carriers is to be used for initial access. The multiple component carrier information may be component carrier indexes. Communication devices may exchange component carrier indexes during a setup or updating procedure such as an X2 setup or updating procedure.

Abstract: A method performed by a base station includes generating a request for resource status information, sending the generated request to a neighboring base station, receiving one or more resource status update messages from the neighboring base station in response to the requested resource status information, and performing load balancing operations in dependence upon the received one or more resource status update messages.

Abstract: A mobile communications system is proposed in which mobile communications devices are arranged to transmit signals to and to receive signals from a base station using one or a subset of available sub-bands, with the base station being configured to move the mobile communications devices between the sub-bands. An anchor sub-band is also provided on which idle mobile communications devices camp until they are moved to one or more other sub-bands in addition to or instead of the anchor sub-band.

Abstract: Set forth herein are processes and materials for sintering dense thin green films comprising lithium-stuffed garnet powder and a binder to obtain sintered lithium-stuffed garnet thin films. Some of the processes, herein, include providing a first setter and a second setter, wherein the first setter and second setter each include at least 5 atomic % lithium (Li) per setter; placing the green film on the first setter; placing the second setter within 2 cm of the green film but not in contact with the green film; and heating the green film to at least 900 C.

Abstract: A communication apparatus is disclosed, which comprises a base station module and an access point module for providing wireless connectivity to a communication network to at least one mobile communication device; an interface for coupling the base station module and the access point module for performing at least one of: a channel restriction operation; a power restriction operation; an intelligent uplink scheduling operation; a carrier frequency reselection operation; and a traffic steering operation; whereby alleviating an interference arising due to coexistence of the base station module and the access point module.

Abstract: A mobile station which communicates with a base station includes a transceiver configured to receive a downlink control channel, and a controller configured to determine whether C-RNTI is included in the downlink control channel. The controller is further configured to determine that resource allocation in the downlink control channel overrides persistent downlink resource allocation for a Transmission Time Interval (TTI) if the C-RNTI is included in the downlink control channel. The transceiver is further configured to receive a Hybrid Automatic Repeat Request (HARQ) transmission by using persistent downlink resources.

Abstract: Provided herein are defect-free solid-state separators which are useful as Li+ ion-conducting electrolytes in electrochemical cells and devices, such as, but not limited to, rechargeable batteries. In some examples, the separators have a Li+ ion-conductivity greater than 1*10?3 S/cm at room temperature.

Abstract: A method performed by a base station includes generating a request for resource status information, sending the generated request to a neighboring base station, receiving one or more resource status update messages from the neighboring base station in response to the requested resource status information, and performing load balancing operations in dependence upon the received one or more resource status update messages.

Abstract: A mobile communications system is proposed in which mobile communications devices are arranged to transmit signals to and to receive signals from a base station using one or a subset of available sub-bands, with the base station being configured to move the mobile communications devices between the sub-bands. An anchor sub-band is also provided on which idle mobile communications devices camp until they are moved to one or more other sub-bands in addition to or instead of the anchor sub-band.

Abstract: A communication apparatus is disclosed, which comprises a base station module and an access point module for providing wireless connectivity to a communication network to at least one mobile communication device; an interface for coupling the base station module and the access point module for performing at least one of: a channel restriction operation; a power restriction operation; an intelligent uplink scheduling operation; a carrier frequency reselection operation; and a traffic steering operation; whereby alleviating an interference arising due to coexistence of the base station module and the access point module.

Abstract: A mobile station which communicates with a base station includes a transceiver configured to receive a downlink control channel, and a controller configured to determine whether C-RNTI is included in the downlink control channel. The controller is further configured to determine that resource allocation in the downlink control channel overrides persistent downlink resource allocation for a Transmission Time Interval (TTI) if the C-RNTI is included in the downlink control channel. The transceiver is further configured to receive a Hybrid Automatic Repeat Request (HARQ) transmission by using persistent downlink resources.

Abstract: A time-to-digital converter obtains a Start signal to indicate the start of an event, and a Stop signal whose assertion indicates the stop of the event. The Stop signal can be asserted multiple times due to false indications of the event stop. The TDC continuously monitors the Stop signal to generate a separate digital value for the duration from the event's starting time to each assertion of the Stop signal. The digital values can be analyzed to select the true duration of the event. Other features and embodiments are also provided.

Abstract: A continuous or semi-continuous process for the preparation of ethylene glycol from a carbohydrate source including: reacting, in a reactor, at a temperature in the range from equal to or more than 170° C. to equal to or less than 270° C., at least a portion of a carbohydrate source in the presence of hydrogen, a solvent, and a catalyst system, to yield ethylene glycol; wherein the catalyst system includes: a homogeneous catalyst, which homogeneous catalyst contains tungsten; and a heterogeneous catalyst, which heterogeneous catalyst contains one or more transition metals from groups 8, 9 and 10 of the Periodic Table of the Elements supported on a carrier; and wherein continuously or periodically additional heterogeneous catalyst is added to the reactor. Further described is a catalyst system that can be used in such a process.

Abstract: Disclosed are novel gene therapy constructs containing both HEXA and HEXB genes to treat GM2 gangliosidoses, including Sandhoff disease and Tay-Sach's disease. Also described are co-treatments using chaperone and anti-inflammatory agents to enhance the effects of gene therapy.

Abstract: A mobile station which communicates with a base station includes a transceiver configured to receive a downlink control channel, and a controller configured to determine whether C-RNTI is included in the downlink control channel. The controller is further configured to determine that resource allocation in the downlink control channel overrides persistent downlink resource allocation for a Transmission Time Interval (TTI) if the C-RNTI is included in the downlink control channel. The transceiver is further configured to receive a Hybrid Automatic Repeat Request (HARQ) transmission by using persistent downlink resources.

Abstract: A process for the production of ethylene glycol including the steps of: (i) providing, to a first reactor, a carbohydrate source, a solvent, hydrogen, a first heterogeneous catalyst, which first heterogeneous catalyst contains one or more transition metals from groups 8, 9 and 10 of the Periodic Table of the Elements, and a homogeneous catalyst, which homogeneous catalyst contains tungsten; (ii) reacting, in the first reactor, at a temperature in the range from equal to or more than 170° C. to equal to or less than 270° C.

Abstract: A process for the production of ethylene glycol including the steps of: (i) providing, to a first reactor, a carbohydrate source, a solvent, hydrogen, a first heterogeneous catalyst, which first heterogeneous catalyst contains one or more transition metals from groups 8, 9 and 10 of the Periodic Table of the Elements, and a homogeneous catalyst, which homogeneous catalyst contains tungsten; (ii) reacting, in the first reactor, at a temperature in the range from equal to or more than 170° C. to equal to or less than 270° C.

Abstract: A continuous or semi-continuous process for the preparation of ethylene glycol from a carbohydrate source including: reacting, in a reactor, at a temperature in the range from equal to or more than 170° C. to equal to or less than 270° C., at least a portion of a carbohydrate source in the presence of hydrogen, a solvent, and a catalyst system, to yield ethylene glycol; wherein the catalyst system includes: a homogeneous catalyst, which homogeneous catalyst contains tungsten; and a heterogeneous catalyst, which heterogeneous catalyst contains one or more transition metals from groups 8, 9 and 10 of the Periodic Table of the Elements supported on a carrier; and wherein continuously or periodically additional heterogeneous catalyst is added to the reactor. Further described is a catalyst system that can be used in such a process.