Abstract: The present invention relates to a product comprising a solid substrate and a moiety of formula (I) linked thereto: wherein X, X? and R are as defined herein. The product is useful for immobilising target molecules such as molecules of biochemical interest to solid substrates for numerous applications, such as affinity chromatography, ELISA, biotechnological assay techniques and solid phase peptide synthesis.

Abstract: The present invention relates to the use of a compound comprising a moiety of formula (I) as a reagent for protecting a thiol group in a thiol compound wherein X, X? and Y are as defined herein. The protecting group methodology of the present invention allows straightforward and selective protection of thiol groups. Cleaving of the thiol group to regenerate the thiol functional group is also facile and controllable. The present invention further provides an analogous protecting group methodology directed to protection of disulfide groups.

Abstract: The present invention relates to the use of a compound containing a moiety of formula (I) as a reagent for linking a compound of formula R1—H which comprises a first functional moiety of formula F1 to a second functional moiety of formula F2 wherein X, X?, Y, R1, F1 and F2 are as defined herein. The present invention also provides related processes and products. The present invention is useful for creating functional conjugate compounds, and specifically conjugates in which at least one of the constituent molecules carries a thiol group.

Abstract: A protective apparatus for an article, the apparatus including a surrounding sidewall having a first end portion and an opposing second end portion, the sidewall also having a perpendicularly oriented first margin portion and an opposing second margin portion, also with a primary interior. The interior includes a plurality of first and second chambers that are intersticed in position to one another. In addition, included is a plurality of particulate items loosely disposed within each of the first and second chambers and a structure for removable engagement positioned adjacent to the first and second margins. The removable engagement structure facilitates the first and second margins to be removably engaged allowing the surrounding sidewall to envelope the article. The primary interior can be evacuated, thus removing the air spaces between the particulate items and in the interior resulting in rigidifying the surrounding sidewall, thus protecting the article.

Abstract: Apparatus and methods for treating tissue at or near a sphincter provide for transluminal introduction of an energy delivery device. The device includes a tissue compression member to compress target tissue at or near the sphincter. A radiofrequency energy source is coupleable to the delivery device to deliver radiofrequency energy to the target tissue. Energy is delivered to heat the tissue to a desired temperature. The desired temperature is selected to induce an injury-healing response or to inducing shrinkage of collagen fibers in the target tissue to thereby reduce laxity in the target tissue.

Abstract: A team roping training apparatus that comprises a motor having a motor shaft, a spool having a spool shaft, and a switch to selectively energize the motor. The spool is selectively rotatable with the motor shaft such that when rotation of shaft is impeded through a roper's grasping of an attached rope, the spool is disengaged form the motor shaft. According to the preferred embodiment, such selective rotation is accomplished with a clutch mechanically coupling the spool shaft with the motor shaft.

Abstract: Techniques are disclosed for connecting a user to all of his resources (e.g. remote desktop or remote application) in a deployment of server farm(s). The user's client sends a message to the deployment requesting any disconnected resources for the user and/or any active resources communicating with a different client. The deployment determines what those resources are, then strips out redundant information (e.g. two resources are remote applications executing within the same session) and sends a stripped list to the client, which reconnects. The client first reconnects to a resource that is not a VM and stores any user input (e.g. credentials) prompted for during that log in. Then, it reconnects to the other resources in parallel, using in these later reconnections any input received from the client during the first reconnection.

Abstract: Exemplary techniques for enabling single sign-on to an operating system configured to conduct a remote presentation session are disclosed. In an exemplary embodiment, a user credential can be encrypted using an encryption key generated by a remote presentation session server and sent to a client. The client can send the encrypted user credential to the remote presentation session server. The remote presentation session server can decrypt the user credential and use it to log a user into an operating system running on the remote presentation session server. In addition to the foregoing, other techniques are described in the claims, the detailed description, and the figures.

Abstract: A wireless voice recognition control system for controlling the operation of an electric welder power supply by operator voice commands is disclosed. The system includes a remote module carried by the welder and a host module interfaced with the electric welder power supply. The remote module compares voice commands by the welder to preprogrammed voice command templates and operates to generate and broadcast a wireless signal when a spoken voice command matches a voice command template. The host module operates to receive the wireless signal and is configure to operate the electric welder power supply accordingly. In other embodiments, the host module and remote module operate to provide an audible feedback or acknowledgement to the welder. Other embodiments are also disclosed.

Abstract: A device for projecting images from a video generating device such as a computer, television receiver, or similar device onto a screen or other surface is described in this invention. The device uses a rotating disk containing numerous lenses to direct a light beam from a laser or other light source towards the screen. In one embodiment, a pulsed laser light from red, green, and blue lasers are combined into a single light pulse that is transmitted through the rotating disk that transmit each light pulse to a specific location on the screen.

Abstract: Apparatus and methods for treating tissue at or near a sphincter provide for transluminal introduction of an energy delivery device. The device includes a tissue compression member to compress target tissue at or near the sphincter. A radiofrequency energy source is coupleable to the delivery device to deliver radiofrequency energy to the target tissue. Energy is delivered to heat the tissue to a desired temperature. The desired temperature is selected to induce an injury-healing response or to inducing shrinkage of collagen fibers in the target tissue to thereby reduce laxity in the target tissue.

Abstract: A temperature changing container includes a plurality of walls joined to form an enclosure which seals contents of the enclosure within the walls. One of the walls includes a depression extending into the enclosure. Upon activation, chemicals at least partially disposed within the depression change temperature.

Abstract: A pointer assembly includes a guide, a helical drive member supported in the guide, a motor for axially rotating the helical drive member, a follower carried by the helical drive member, and a pointer coupled to the follower and movable relative to the guide for indicating a measured value, wherein axial rotation of the helical drive member in a clockwise rotation causes the follower and the pointer to move in a first direction relative to the guide and axial rotation of the helical drive member in a counterclockwise rotation causes the follower and the pointer to move in a second direction relative to the guide.

Abstract: Embodiments include systems and methods of detecting and assessing multiple types of risks related to mortgage lending. One embodiment includes a system and method of detecting and assessing risks including fraud risks, early payment default risks, and risks related to fraudulently stated income on loan applications. One embodiment includes a computerized method that includes creating a combined risk detection model based on a plurality of risk detection models and using the combined risk detection model to evaluate loan application data and generate a combined risk score that takes into account interaction of different types of risks individually and collectively detected by the plurality of risk detection models.

Abstract: A cooked and de-boned substantially intact slab of rib meat is provided. A process for preparing a de-boned rib meat product from a pork or beef rib cut is also provided. The process for preparing the rib meat product involves cooking a length of rib meat having rib bones embedded therein at a temperature and for a time sufficient to enable the removal of the rib bones from the length of rib meat, while maintaining a substantially intact length of rib meat.

Abstract: Various embodiments provide an electrosurgical instrument with a disposable electrosurgical cartridge. In one embodiment, the cartridge has first and second energy-delivery surfaces that carry first and second opposing polarity conductors coupled to a voltage source, together with first and second temperature-responsive variable impedance bodies exposed partly in the respective-delivery surfaces. The cartridge further carries a slidable blade member. The temperature-responsive variable impedance bodies are coupled to the voltage source by series and parallel circuitry. In use, the variable impedance bodies are adapted to modulate current flow and ohmic heating in engaged tissue by providing controlled current paths in the tissue and through the variable impedance bodies as the temperature-responsive bodies sense the temperature of adjacent engaged tissue.

Abstract: Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating acute wounds, chronic wounds and/or a wound or epithelial tissue surface that contains bacterial biofilm, including unexpected synergy between bismuth-thiol (BT) compounds and certain antibiotics, to provide topical formulations including antiseptic formulations, for management and promotion of wound healing and in particular infected wounds. Previously unpredicted antibacterial properties and anti-biofilm properties of disclosed BT compounds and BT compound-plus-antibiotic combinations are also described, including preferential efficacies of certain such compositions for treating gram-positive bacterial infections, and distinct preferential efficacies of certain such compositions for treating gram-negative bacterial infections.

Abstract: A method, a system, and a computer program for recapturing electronic devices no longer of use to their owners. The method, which is implemented by the computer program, broadly comprises the steps of identifying at least one electronic device no longer of use to the device's owner by managing one or more identification parameters; matching the device with a recapture offer so as to incentivize the owner to donate or sell the device; notifying the device owner of the recapture offer; and acquiring the device from the owner to complete recapture of the device.

Abstract: The invention provides a pyrimidine compound of formula (I): wherein R1 and R2 have any of the values defined herein; or a pharmaceutically acceptable salt thereof. The compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.

Abstract: A latching system including a latch assembly, a cup, and a keeper plate. The latch assembly includes a base, a lever, and a catch. The lever is pivotally connected to the base and the catch is pivotally connected to the lever. The base is pivotally attached to the cup such that it rotates about an axis of rotation that is perpendicular in direction in relation to the direction of the axis of rotation of the lever relative to the base. The keeper plate includes a keeper projection. The lever can be lifted and the latch assembly rotated about the axis of rotation of the base to clear the keeper from the catch and thereby allow the opening of a first closure member relative to a second closure member.