Patents by Inventor James A. Glazier

James A. Glazier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7961329
    Abstract: A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multichannel sensor for detecting the presence of several targets with a single microchip sensor is described. A multichannel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: June 14, 2011
    Assignee: Indiana University Research & Technology Corporation
    Inventors: James A. Glazier, Dragos Amarie
  • Patent number: 7852482
    Abstract: A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single microchip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: December 14, 2010
    Assignee: Indiana University Research & Technology Corporation
    Inventors: James A. Glazier, Bogdan Dragnea, Dragos Amarie
  • Publication number: 20100290309
    Abstract: Disclosed is a method and apparatus for manipulating fluids. The apparatus may include a microfluidic structure including inlet channels (1 and 2) and outlet channels (306, 307, 308, 309, 310, 311, 312, 313, and 314) oriented among bifurcated (5), trifurcated (6) and merging junctions (7 and 8). The apparatus splits and merges fluids flowing in the channels to produce successive dilutions of the fluids within the outlet channels. Multiple apparatus may be combined in serial, parallel, combined serial and parallel and/or stacked configurations. One or more apparatus may be used alone or to provide various devices or chambers with the diluted fluids.
    Type: Application
    Filed: September 18, 2008
    Publication date: November 18, 2010
    Applicant: INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORA
    Inventors: James A. Glazier, Stephen C. Jacobson, Dragos Amarie
  • Publication number: 20100188663
    Abstract: A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single microchip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
    Type: Application
    Filed: March 31, 2010
    Publication date: July 29, 2010
    Inventors: James A. Glazier, Dragos Amarie
  • Publication number: 20100189603
    Abstract: A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single microchip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
    Type: Application
    Filed: March 31, 2010
    Publication date: July 29, 2010
    Inventors: James A. Glazier, Bogdan Dragnea, Dragos Amarie
  • Publication number: 20100188664
    Abstract: A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single micro-chip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
    Type: Application
    Filed: March 31, 2010
    Publication date: July 29, 2010
    Inventors: James A. Glazier, Dragos Amarie
  • Patent number: 7724373
    Abstract: A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprising a light transmissive substrate on which an array of surface plasmon resonant (SPR) elements is mounted is described. A multi-channel sensor for detecting the presence of several targets with a single micro-chip sensor is described. A multi-channel sensor including collections of SPR elements which are commonly functionalized to one of several targets is also described. The detectors sense changes in the resonant response of the SPR elements indicative of binding with the targets.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: May 25, 2010
    Assignee: Indiana University Research & Technology Corporation
    Inventors: James A. Glazier, Bogdan Dragnea, Dragos Amarie
  • Publication number: 20070153284
    Abstract: A sensor for detecting the presence of a target analyte, ligand or molecule in a test fluid, comprises a light transmissive substrate, an array of surface plasmon resonant (SPR) elements mounted thereon, a light source arranged to direct light into the SPR elements, and a detector arranged to detect light transmitted through the SPR elements. The SPR elements may include a dielectric polystyrene sphere having a spherical diameter of about 770 nm with a gold coating layer about 150 nm thick. The interface between the SPR elements and the substrate forms a pinhole with a diameter less than the wavelength of the light directed into the elements to produce a near-field coupling mode within the micro-sized SPR elements. In specific embodiments, the pinhole diameter ranges between 150-200 nm. The SPR elements are contained within a molded PDMS chip that may incorporate micro-fluidic components, such as a pump and valves, to control flow of the test fluid across the SPR elements.
    Type: Application
    Filed: December 15, 2006
    Publication date: July 5, 2007
    Inventors: James Glazier, Bogdan Dragnea, Dragos Amarie
  • Patent number: 5950463
    Abstract: A vehicle highly visible, convenient locking apparatus which locks all four wheels of a vehicle to prevent it from being driven or towed is disclosed. The apparatus which holds a brake pedal having a leg, close to a floor of a vehicle comprises: a mountable base having a lower side portion and an opposite side portion; and, a longitudinal member having a bottom end portion adapted to releasably engage in the opposite side portion of the base; a peddle holding/lock member carried by the longitudinal member. In use the base is mounted on the floor of the vehicle, beneath the brake pedal; the longitudinal member is releasably engaged in the base; the peddle is depressed, engaging the brakes; and the peddle holding/lock member is locked on the longitudinal member thereby holding the brake pedal in an engaged position and generally preventing the longitudinal member from turning.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: September 14, 1999
    Inventors: James Glazier, Ken Toole
  • Patent number: 5579894
    Abstract: A product transfer apparatus for transferring individual product from a rotary feeding station to downstream apparatus such as a cartoner conveyor in preselected count stacks for subsequent discharge at a cartoner machine. Stacks of product are formed by dropping the product into stacks on a transfer conveyor and from there dropping the stacks directly into buckets of a cartoner conveyor. A transfer bucket conveyor is disposed beneath and transverse to an axis of the rotary feeding station and includes an upper fill run and a lower discharge run of product transfer buckets. The cartoner conveyor is disposed beneath and aligned with the transfer bucket conveyor and includes a series of cartoner product buckets operating in speed register with the lower run of product transfer buckets for receiving the preselected count stacks from the lower discharge run.
    Type: Grant
    Filed: April 11, 1995
    Date of Patent: December 3, 1996
    Assignee: R. A. Jones & Co. Inc.
    Inventors: James A. Glazier, Frank G. Oliverio
  • Patent number: 5538159
    Abstract: A portable wood dispenser comprising a housing having parallel side walls, a back wall, a floor and a roof with legs depending from the floor for the support thereof; a plurality of horizontal divider members and a plurality of vertical divider members within the housing with the horizontal divider members parallel with the floor and the vertical divider members parallel with the side walls to thereby define a plurality of compartments in rows and columns adapted for the receipt of firewood; a plurality of doors, each door adapted to be pivotally secured with respect to an associated compartment, each door adapted to be opened to allow the placement of firewood within the compartment and for the dispensing of the firewood therefrom; a lock secured to each door with an associated locking plate secured to the vertical extent of each compartment remote from the hinge, the lock adapted to secure the door in the closed orientation; and a key positionable within each lock and adapted to unlock a door to allow its o
    Type: Grant
    Filed: November 7, 1994
    Date of Patent: July 23, 1996
    Inventors: Ted G. Snyder, James Glazier, Gerry Huggins
  • Patent number: 4578927
    Abstract: A barrel loader for a cartoner having a product conveyor and a carton conveyor. A plurality of pusher heads are carried on two spaced endless chains. A cam track between the chains cooperates with cam followers on the heads to cam the heads toward the product conveyor to thrust product into the cartons. A switch on the cam track diverts a pusher head from the cam track upon detecting the absence of a carton with which the pusher head is associated.
    Type: Grant
    Filed: November 12, 1982
    Date of Patent: April 1, 1986
    Assignee: R. A. Jones & Co. Inc.
    Inventors: Eric W. Scarpa, James A. Glazier