Patents by Inventor James A. Hale
James A. Hale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8425308Abstract: An approach is provided in which a disincentive is provided during the execution of a video game program that is operated by a current user. One or more disincentive factors are identified that correspond to the current user. The identified disincentive factors are compared with current time factors. Based on the comparison, one or more game characteristics are altered with the game characteristics being altered in order to provide a disincentive to continued operation of the video game program by the current user.Type: GrantFiled: September 7, 2011Date of Patent: April 23, 2013Assignee: International Business Machines CorporationInventors: Joel Duquene, Ollie James Hales, Morris Stanley Johnson, Jr., Adrienne Yvette Miller
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Publication number: 20130059666Abstract: An approach is provided in which a disincentive is provided during the execution of a video game program that is operated by a current user. One or more disincentive factors are identified that correspond to the current user. The identified disincentive factors are compared with current time factors. Based on the comparison, one or more game characteristics are altered with the game characteristics being altered in order to provide a disincentive to continued operation of the video game program by the current user.Type: ApplicationFiled: September 7, 2011Publication date: March 7, 2013Applicant: International Business Machines CorporationInventors: Joel Duquene, Ollie James Hales, Morris Stanley Johnson, JR., Adrienne Yvette Miller
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Patent number: 8003649Abstract: The invention concerns bicyclic compounds of Formula I wherein the integers X1, X2, X3, Ring A, R4, R5 and m are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of androgen-receptor associated conditions.Type: GrantFiled: December 18, 2008Date of Patent: August 23, 2011Assignee: AstraZeneca ABInventors: Robert Hugh Bradbury, Alfred Arthur Rabow, Neil James Hales
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Patent number: 7886945Abstract: A garment hanger comprises a header card and a clamp, the header card being preferably “free-floating” relative to the clamp to give a prospective purchaser a sense that the clamp is attached more to the garment than to the header card and that the card is thus disposable after purchase. In one embodiment, a hanger for displaying and holding an article such as a pair of gloves comprises a clothespin-like clamp comprising a pair of jaws resiliently biased about a pivot region to a closed, article-holding position, and a header defining an opening for receiving the pivot region of the clamp. Preferably, the opening in the header is larger than the pivot region of the clamp so as to provide for relative movement between the clamp and the header.Type: GrantFiled: January 25, 2007Date of Patent: February 15, 2011Assignee: Mechanix Wear, Inc.Inventors: Thomas Fitzgerald, John Caper, James Hale, Brian J. Lunniss
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Publication number: 20100137243Abstract: Compounds of Formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, and compounds as shown in Formula (I) wherein C is for example (D), (E), (F); wherein A and B are independently selected from (i) and (ii); R2a to R3b are independently selected from hydrogen and fluorine; R1a and R1b are independently selected from, for example, hydroxy, —NHC(?W)R4, (a) and (b); wherein W is O or S; R4 is, for example, hydrogen, amino, (1-4C)alkyl; HET-1 is, for example, a C-linked 5-membered heteroaryl ring; HET-2 is, for example, an N-linked 5-membered, fully or partially unsaturated heterocyclic ring; are useful as antibacterial agents; and processes for their manufacture and pharmaceutical compositions containing them are described.Type: ApplicationFiled: May 28, 2008Publication date: June 3, 2010Applicant: AstraZeneca ABInventors: Michael Barry Gravestock, Neil James Hales, Michael Lingrad Swaim, Sheila Irene Hauck, Stuart Dennett Mills
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Patent number: 7709503Abstract: Compounds of Formula (1) and their pharmaceutically acceptable salts are described: Formula (1) Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.Type: GrantFiled: September 10, 2004Date of Patent: May 4, 2010Assignee: AstraZeneca ABInventors: Oluyinka Morenike Green, Kenneth Gregory Hull, Haihong Ni, Sheila Irene Hauck, George Byron Mullen, Alexander Louis Breeze, Neil James Hales, David Timms
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Publication number: 20100016279Abstract: The invention concerns bicyclic compounds of Formula I wherein the integers X1, X2, X3, Ring A, R4, R5 and m are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the prevention or treatment of androgen-receptor associated conditions.Type: ApplicationFiled: December 18, 2008Publication date: January 21, 2010Applicant: AstraZeneca ABInventors: Robert Hugh Bradbury, Alfred Arthur Rabow, Neil James Hales
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Patent number: 7498350Abstract: A compound of the formula (I), or a pharmaceutically-acceptable salt, or in-vivo hydrolysable ester thereof: Wherein C is selected from (D) and (E), R2a, R6a, and R3a are independently selected from for example H, CF3, Me and Et; R2b and R6b are independently selected from for example H, F, CF3, Me and Et; R1b is for example optionally substituted diazolyl, triazolyl or tetrazolyl; R4 is for example an optionally substituted 5- or 6-membered heterocyclic ring system. Methods for making compounds of the formula (I), compositions containing them and their use as antibacterial agents are also described.Type: GrantFiled: November 24, 2003Date of Patent: March 3, 2009Assignee: AstraZeneca ABInventors: Michael Barry Gravestock, Neil James Hales, Folkert Reck, Fei Zhou
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Patent number: 7473699Abstract: Compounds of the formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, wherein —N-HET is, for example, (Ic) or (If) wherein R1 is (1-4C)alkyl; Q is selected from, for example, Q1 wherein R2 and R3 are independently hydrogen or fluoro; T is selected from a range of groups, for example, wherein m is 0, 1 or 2; are useful as antibacterial agents; and processes for their manufacture and pharmaceutical compositions containing them are described.Type: GrantFiled: February 25, 2003Date of Patent: January 6, 2009Assignee: AstraZeneca ABInventors: Michael Barry Gravestock, Neil James Hales, Folkert Reck, Fei Zhou, Paul Robert Fleming, Daniel Robert Carcanague, Marc Michel Girardot
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Patent number: 7396847Abstract: Compounds of the formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, and compounds as shown in (I) wherein C is for example wherein A and B are independently selected from R2a to R3b are independently selected from hydrogen and fluorine; R1a and R1b are independently selected from, for example, hydroxy, —NHC(?W)R4, wherein W is O or S; R4 is, for example, hydrogen, amino, (1-4C)alkyl; HET-1 is, for example, a C-linked 5-membered heteroaryl ring; HET-2 is, for example, an N-linked 5-membered, fully or partially unsaturated heterocyclic ring; are useful as antibacterial agents; and processes for their manufacture and pharmaceutical compositions containing them are described.Type: GrantFiled: September 9, 2002Date of Patent: July 8, 2008Assignee: AstraZeneca ABInventors: Michael Barry Gravestock, Neil James Hales, Michael Lingard Swain, Sheila Irene Hauck, Stuart Dennett Mills
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Publication number: 20070119880Abstract: A garment hanger comprises a header card and a clamp, the header card being preferably “free-floating” relative to the clamp to give a prospective purchaser a sense that the clamp is attached more to the garment than to the header card and that the card is thus disposable after purchase. In one embodiment, a hanger for displaying and holding an article such as a pair of gloves comprises a clothespin-like clamp comprising a pair of jaws resiliently biased about a pivot region to a closed, article-holding position, and a header defining an opening for receiving the pivot region of the clamp. Preferably, the opening in the header is larger than the pivot region of the clamp so as to provide for relative movement between the clamp and the header.Type: ApplicationFiled: January 25, 2007Publication date: May 31, 2007Applicant: MECHANIX WEAR, INC.Inventors: Thomas Fitzgerald, John Caper, James Hale, Brian Lunniss
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Patent number: 7199143Abstract: Compounds of the formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, wherein —N-HET is, for example, (Ic) or (If) wherein R1 is, for example, halogen or a (1–4C)alkyl group which is substituted by one substituent selected from, for example, hydroxy, (1–4C)alkoxy, amino, cyano or azido; Q is selected from, for example, Q1 wherein R2 and R3 are independently hydrogen or fluoro; T is selected from a range of groups, for example, wherein m is 0, 1 or 2; are useful as antibacterial agents; and processes for their manufacture and pharmaceutical compositions containing them are described.Type: GrantFiled: February 25, 2003Date of Patent: April 3, 2007Assignee: AstraZeneca ABInventors: Michael Barry Gravestock, Neil James Hales, Folkert Reck, Fei Zhou, Paul Robert Fleming, Daniel Robert Carcanague
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Patent number: 7192974Abstract: Compounds of the formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, (I) R1a is NH(C?W)R5 or (a); W is O or S; R2 and R3 are for example H or F; R1 is for example hydrogen, or halogen; R5 is selected from hydrogen, (2–6C)alkyl (optionally substituted); R6 and R7 are independently selected from hydrogen, and (1–4C)alkyl (optionally substituted); wherein R4 is either a hydroxymethyl substituent on C-4? of the isoxazoline ring; or R4 is a hydroxymethyl substituent on C-5? of the isoxazoline ring and the stereochemistry at C-5? of the isoxazoline ring and at C-5 of the oxazolidinone ring is selected, such that the compound of formula (I) is a single diastereomer; are useful as antibacterial agents; and processes for their manufacture and pharmaceutical compositions containing them are describedType: GrantFiled: February 24, 2004Date of Patent: March 20, 2007Assignee: AstraZeneca ABInventors: Michael Barry Gravestock, Daniel Robert Carcanague, Neil James Hales
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Patent number: 7186738Abstract: Compounds of the formula (I), or a pharmaceutically-acceptable salts, or in-vivo-hydrolysable esters thereo Formula (I): wherein N-HeT is for example triazolyl; Q is for example phenyl or pyridyl, substituted with: T is for example selected from (TAa1 to TAa12) such as (TAa1) and (TAa5): R4h, R5h, R6h are for example selected from hydrogen, (1–4C)alkyl, (1–4C)alkoxy-carbonyl, (1–4C)alkanoyl and carbamoyl; processes for making them, compositions containing them and their use as antibacterial agents are described.Type: GrantFiled: March 16, 2004Date of Patent: March 6, 2007Assignee: AstraZeneca ABInventors: Michael Barry Gravestock, Neil James Hale, Sheila Irene Hauck
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Patent number: 7157482Abstract: Compounds of the formula (I), or a pharmaceutically-acceptable salts, or in-vivo-hydrolysable esters thereof, wherein: N—HET is for example triazolyl substituted with R1; R1 is for example optionally substituted (1-4C)alkyl; Q is for example phenyl or pyridyl, substituted with T; T is for example selected from (TAa1 to TAa12) such as (TAa1 and TAa5); formula (II): R4h, R5h, R6h are for example selected from hydrogen, (1-4C)alkyl, (1-4C)alkoxycarbonyl, (1-4C)alkanoyl and carbamoyl; processes for making them, compositions containing them and their use as antibacterial agents are described.Type: GrantFiled: March 16, 2004Date of Patent: January 2, 2007Assignee: AstraZeneca ABInventors: Michael Barry Gravestock, Neil James Hale, Sheila Irene Hauck
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Patent number: 6806389Abstract: The invention relates to the use of an immobilized transition metal carbonyl complex as a catalyst in the Pauson-Khand reaction and to processes using such as catalyst.Type: GrantFiled: April 19, 2002Date of Patent: October 19, 2004Assignee: AstraZeneca ABInventors: Alex Christian Comely, Sue Elizabeth Gibson, Neil James Hales
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Publication number: 20010001101Abstract: The present invention provides a phenanthroline derivative of formula (I) 1Type: ApplicationFiled: December 20, 2000Publication date: May 10, 2001Applicant: Zeneca LimitedInventors: Philip Neil Edwards, Michael Stewart Large, Neil James Hales
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Patent number: D521976Type: GrantFiled: March 31, 2005Date of Patent: May 30, 2006Assignee: Motorola, Inc.Inventors: Robert B. Widmayer, David T. Andersen, Richard H. Burzynski, David M. Frendreiss, James A. Hale, James W. Turocy, Peter P. Walter, Horng L. Wang
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Patent number: D524800Type: GrantFiled: March 31, 2005Date of Patent: July 11, 2006Assignee: Motorola, Inc.Inventors: Richard H. Burzynski, James W. Turocy, Horng L. Wang, Robert B. Widmayer, James A. Hale
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Patent number: D524801Type: GrantFiled: March 31, 2005Date of Patent: July 11, 2006Assignee: Motorola, Inc.Inventors: Robert B. Widmayer, David T. Andersen, Richard H. Burzynski, David M. Frendreiss, James A. Hale, James W. Turocy, Peter P. Walter, Horng L. Wang