Patents by Inventor James A. Hale

James A. Hale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6200974
    Abstract: The present invention provides a phenanthroline derivative of formula (I) wherein, for example, R1 is hydrogen, carboxy, cyano, nitro, (1-4C)alkyl, (1-6C)alkoxycarbonyl, (1-4C)alkylamino, (2-4C)alkanoyl, (1-4C)alkoxy-(2-4C)alkoxy-(2-4C)alkoxycarbonyl or N-[amino-(2-8C)alkyl]carbamoyl; R2 is, for example, hydrogen, carboxy, (1-6C)alkoxycarbonyl, carbamoyl, N-(1-8C)alkylcarbamoyl, N,N-di-(1-8C)alkylcarbamoyl, N-(1-4C)alkylcyclohexylcarbamoyl, 1,2,3,4-tetrahydro-isoquinolin-2-ylcarbonyl or N,N-[di-(1-4C)alkyl]thiocarbamoyl; R3 and R4, which may be the same or different, are, for example, hydrogen or halo; and R5 is, for example, hydrogen, di-(1-4C)alkylamino or halo; or a pharmaceutically-acceptable salt thereof. The invention further provides pharmaceutical compositions comprising phenanthroline derivatives, processes for making the same and their use in producing an anti-fibroproliferative effect.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: March 13, 2001
    Assignee: Zeneca Limited
    Inventors: Philip Neil Edwards, Michael Stewart Large, Neil James Hales
  • Patent number: 5916898
    Abstract: The present invention provides a phenanthroline derivative of formula (I) ##STR1## wherein, for example, R.sup.1 is hydrogen, carboxy, cyano, nitro, (1-4C)alkyl, (1-6C)alkoxycarbonyl, (1-4C)alkylamino, (2-4C)alkanoyl, (1-4C)alkoxy-(2-4C)alkoxy-(2-4C)alkoxycarbonyl or N-?amino-(2-8C)alkyl!carbamoyl;R.sup.2 is, for example, hydrogen, carboxy, (1-6C)alkoxycarbonyl, carbamoyl, N-(1-8C)alkylcarbamoyl, N,N-di-(1-8C)alkylcarbamoyl, N-(1-4C)alkylcyclohexylcarbamoyl, 1,2,3,4-tetrahydro-isoquinolin-2-ylcarbonyl or N,N-?di-(1-4C)alkyl!thiocarbamoyl;R.sup.3 and R.sup.4, which may be the same or different, are, for example, hydrogen or halo; andR.sup.5 is, for example, hydrogen, di-(1-4C)alkylamino or halo; or a pharmaceutically-acceptable salt thereof.The invention further provides pharmaceutical compositions comprising phenanthroline derivatives, processes for making the same and their use in producing an anti-fibroproliferative effect.
    Type: Grant
    Filed: October 24, 1997
    Date of Patent: June 29, 1999
    Assignee: Zeneca Limited
    Inventors: Philip Neil Edwards, Michael Stewart Large, Neil James Hales
  • Patent number: 5814411
    Abstract: The present invention provides a novel method of rendering a wallboard water-repellent comprising applying to the wallboard a water-repellent composition comprising a hydrogen siloxane component and a high molecular weight silicone.
    Type: Grant
    Filed: February 18, 1997
    Date of Patent: September 29, 1998
    Assignee: General Electric Company
    Inventors: James Hale Merrifield, Donna Ann Riccio
  • Patent number: 5328028
    Abstract: A drum assembly for the collection and disposal of hazardous waste includes an enclosure with an access hole for collecting the waste. After the waste has been collected, the drum is opened and an insert is positioned to cover the access hole. The drum is then closed to form a sealed container.
    Type: Grant
    Filed: August 18, 1993
    Date of Patent: July 12, 1994
    Assignee: Greif Bors. Corporation
    Inventors: James A. Hale, Jean Sawyer, John A. Plunkett, Lou A. Marinaccio
  • Patent number: 5320243
    Abstract: A metal drum and the method of making the same having a detachable lining removable therefrom after a first use to allow for the reuse or recycling of the drum.
    Type: Grant
    Filed: March 31, 1993
    Date of Patent: June 14, 1994
    Assignee: Greif Bros. Corporation
    Inventor: James A. Hale
  • Patent number: 5258086
    Abstract: A fiber drum and the method of making the same having a detachable lining fabricated therewith but removable therefrom after a first use to allow for the reuse or recycling of the drum.
    Type: Grant
    Filed: February 23, 1993
    Date of Patent: November 2, 1993
    Assignee: Greif Bros. Corporation
    Inventor: James A. Hale
  • Patent number: 5244108
    Abstract: A collapsible, fiber, bulk container which is made-up of a plurality of sidewalls joined by connectors to form a tubular body. The body is closed off by top and bottom members telescopically engaging said body. The bottom may be reinforced by a strut member to insure that the bottom does not warp and collapse. A reinforcing strap is also secured around the body.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: September 14, 1993
    Assignee: Greif Bros. Corporation
    Inventor: James A. Hale
  • Patent number: 5232117
    Abstract: A metal drum and the method of making the same having a detachable lining removable therefrom after a first use to allow for the reuse or recycling of the drum.
    Type: Grant
    Filed: April 13, 1992
    Date of Patent: August 3, 1993
    Assignee: Greif Bros. Corporation
    Inventor: James A. Hale
  • Patent number: 5137206
    Abstract: A fiber drum and the method of making the same having a detachable lining fabricated therewith but removable therefrom after a first use to allow for the reuse or recycling of the drum.
    Type: Grant
    Filed: October 17, 1991
    Date of Patent: August 11, 1992
    Assignee: Greif Bros. Corporation
    Inventor: James A. Hale
  • Patent number: 5044502
    Abstract: A fiber drum with an integral skid is made by providing a lower skirt on a drum body. The skirt has cutouts for engagement by mechanized drum handling apparatus. The drum may also include an upper skirt cooperating with the lower skirt to maintain several drums aligned vertically for stacking.
    Type: Grant
    Filed: March 1, 1990
    Date of Patent: September 3, 1991
    Assignee: 501 Greif Bros.
    Inventor: James A. Hale
  • Patent number: 5018641
    Abstract: A barrel or drum, preferably of fibre, with metal chimes responsive to longitudinal compressive forces is provided. The compressive forces urge a diagonal flange of the chimes towards the horizontal thereby expanding the outer circumference of the flange of the chime. The outer circumference of the flange of the chime has a looped or tear-drop shaped high strength hollow beam construction so as to increase the stiffness or "stretch resistance" of the flange.
    Type: Grant
    Filed: April 6, 1990
    Date of Patent: May 28, 1991
    Assignee: Greif Bros. Corp.
    Inventors: Herbert L. Carpenter, Jr., James A. Hale
  • Patent number: 4951833
    Abstract: A barrel or drum, preferably of fibre, with metal chimes responsive to longitudinal compressive forces is provided. The compressive forces urge a diagonal flange of the chimes towards the horizontal thereby expanding the outer circumference of the flange of the chime. The outer circumference of the flange of the chime has a rectangular high strength hollow beam construction so as to increase the stiffness or "stretch resistance" of the flange.
    Type: Grant
    Filed: March 10, 1989
    Date of Patent: August 28, 1990
    Assignee: Greif Brothers Corp.
    Inventors: Herbert L. Carpenter, Jr., James A. Hale
  • Patent number: 4909536
    Abstract: A vehicle leveling strut of the type having a direct-acting hydraulic shock absorber provided with a reciprocable piston rod having a dirt shield mounted thereon. A tubular rolling diaphragm member secured at one end to the shock absorber and to the opposite end to the dirt shield and defining therewith a variable volume chamber adapted to be selectively pressurized and de-pressurized for controlling the distance between the sprung and unsprung portions of an associated vehicle. Located interiorly of the pressurizable chamber and concentrically positioned between the shock absorber and fixedly mounted to the dirt shield is a generally tubular support member upon which is mounted at least one pair of electrical coil windings for sensing changes in the electromagnetic field of each coil winding.
    Type: Grant
    Filed: October 24, 1988
    Date of Patent: March 20, 1990
    Assignee: Monroe Auto Equipment
    Inventor: James A. Hale
  • Patent number: 4852792
    Abstract: A self locking cover/bottom for a fibre drum includes substantially perpendicular projections with inwardly tapered portions which, when in registry with notched portions in the fibre shell sidewall, engage the notched portions (which can bend inwardly) such that an airtight seal can be formed for the drum. An optional feature is the provision of a channel in the bottom to accommodate a tine of a fork lift truck.
    Type: Grant
    Filed: March 2, 1988
    Date of Patent: August 1, 1989
    Assignee: Greif Bros. Corporation
    Inventor: James A. Hale
  • Patent number: D288981
    Type: Grant
    Filed: September 21, 1984
    Date of Patent: March 31, 1987
    Inventor: James Hale