Abstract: An apparatus can be used to apply and remove fluid substances for processing biological samples. The fluid substances can be delivered between a first substrate and a second substrate. One substrate carries a specimen. A layer of the fluid substance is retained in a gap defined by the first and second substrates. One substrate is moved with respect to the second substrate to disperse the fluid substance in the gap.

Abstract: Described herein are truncated EGF receptor polypeptides, nucleic acids encoding them, and methods of using them to help select a method of treatment for an EGFR-related cancer, to predict clinical outcome, and to detect micrometastases or minimal residual disease. High EGFR expression and phosphorylated EGFR predicts poor survival in head and neck cancer patients, but does not correlate with advanced stage disease. In our studies, we determined that clinical biological correlates are likely to be more accurate when different aspects of EGFR are evaluated in combination. We analyzed EGFR phosphorylation, expression and mutations in 60 primary head and neck tumors. We not only found that head and neck tumors with either truncated or activated EGFR tend to have higher tumor and nodal stage, but also discovered three EGFR truncations.

Abstract: An apparatus can be used to apply and remove fluid substances for processing biological samples. The fluid substances can be delivered between a first substrate and a second substrate. One substrate carries a specimen. A layer of the fluid substance is retained in a gap defined by the first and second substrates. One substrate is moved with respect to the second substrate to disperse the fluid substance in the gap.

Abstract: A tire-condition-ascertaining cartridge (100) comprising a scaffoyer structure which performs both scaffolding and fluid-foyer-forming functions. The scaffoyer (600) includes planks and/or derricks which properly posture a first fitting (200), a second fitting (300), an electronics assembly (400), and a power source (500) during cartridge construction. The scaffoyer (600) also forms a fluid foyer to the sensing site and this foyer can be tested for fluid integrity (e.g., leaks) prior to creating the housing capsule (800).

Abstract: A diesel exhaust fluid (DEF) tank for an off-road vehicle including a first conduit channel molded into an exterior surface of the DEF tank, at a first depth, in which the first conduit channel is configured to guide a first conduit along the exterior surface of the DEF tank. The DEF tank further including a second conduit channel molded into the exterior surface of the DEF tank at a second depth, different than the first depth, in which the second conduit channel is configured to guide a second conduit, and the first depth and the second depth are selected to create a vertical gap between the first conduit and the second conduit at an intersection of the conduits.

Abstract: A tire-condition-ascertaining cartridge (100) comprising a scaffoyer structure which performs both scaffolding and fluid-foyer-forming functions. The scaffoyer (600) includes planks and/or derricks which properly posture a first fitting (200), a second fitting (300), an electronics assembly (400), and a power source (500) during cartridge construction. The scaffoyer (600) also forms a fluid foyer to the sensing site and this foyer can be tested for fluid integrity (e.g., leaks) prior to creating the housing capsule (800).

Abstract: Described herein are truncated EGF receptor polypeptides, nucleic acids encoding them, and methods of using them to help select a method of treatment for an EGFR-related cancer, to predict clinical outcome, and to detect micrometastases or minimal residual disease. High EGFR expression and phosphorylated EGFR predicts poor survival in head and neck cancer patients, but does not correlate with advanced stage disease. In our studies, we determined that clinical biological correlates are likely to be more accurate when different aspects of EGFR are evaluated in combination. We analyzed EGFR phosphorylation, expression and mutations in 60 primary head and neck tumors. We not only found that head and neck tumors with either truncated or activated EGFR tend to have higher tumor and nodal stage, but also discovered three EGFR truncations.

Abstract: An apparatus can be used to apply and remove fluid substances for processing biological samples. The fluid substances can be delivered between a first substrate and a second substrate. One substrate carries a specimen. A layer of the fluid substance is retained in a gap defined by the first and second substrates. One substrate is moved with respect to the second substrate to disperse the fluid substance in the gap.

Abstract: A thermo-magnetic actuator includes operative components, preferably in a sealed container, from which a rotatable or translatable shaft extends. The shaft is driven by supplying electrical power to a heater in a closed chamber containing a working fluid that expands upon being heated. The expansion of the fluid drives a piston that, in turn, slides a rack coupled to the shaft. A ferromagnetic target is connected to the rack and attracted by a magnetic field produced by an electromagnet that receives electrical power from the same source as the heater. The attraction of the target causes an end of the target to latch magnetically and mechanically and to open an electrical switch, disconnecting current flow to the heater, without disturbing current flow to the electromagnet. The target is released and the rack and target return to their original positions upon termination of current flow to the electromagnet.

Abstract: Systems and methods for guiding a vehicle and vehicle sensor bias determination methods are disclosed. A method for guiding a vehicle includes a primary antenna of a primary survey-grade GNSS-receiver and a secondary antenna of a secondary GNSS-receiver mounted to the vehicle, which are at least temporarily receiving GNSS-signals of a global positioning system. A plurality of physical sensors mounted to the vehicle generate physical data indicative of respective measured physical parameters of at least part of the vehicle. The method includes de-biasing the physical data and applying a recursive statistical estimator, such as a Kalman filter, to the de-biased physical data and an output of the primary and secondary GNSS-receivers to determine a position and velocity of the vehicle.

Abstract: A facility for distributing electronic coupons is described. The facility presents to a user indications of each of at least one coupon pack. Each coupon pack comprises a plurality of independently-redeemable electronic coupons. The facility receives user input selecting an indicated coupon pack, and uses payment information associated with the user to collect a price indicated for the selected coupon pack. The facility then makes the selected coupon pack available for use by the user such that the user may redeem any of the electronic coupons of the selected coupon pack.

Abstract: Systems and methods for guiding a vehicle and vehicle sensor bias determination methods are disclosed. A method for guiding a vehicle includes a primary antenna of a primary survey-grade GNSS-receiver and a secondary antenna of a secondary GNSS-receiver mounted to the vehicle, which are at least temporarily receiving GNSS-signals of a global positioning system. A plurality of physical sensors mounted to the vehicle generate physical data indicative of respective measured physical parameters of at least part of the vehicle. The method includes de-biasing the physical data and applying a recursive statistical estimator, such as a Kalman filter, to the de-biased physical data and an output of the primary and secondary GNSS-receivers to determine a position and velocity of the vehicle.

Abstract: Systems and methods for guiding a vehicle and vehicle sensor bias determination methods are disclosed. A method for guiding a vehicle includes a primary antenna of a primary survey-grade GNSS-receiver and a secondary antenna of a secondary GNSS-receiver mounted to the vehicle, which are at least temporarily receiving GNSS-signals of a global positioning system. A plurality of physical sensors mounted to the vehicle generate physical data indicative of respective measured physical parameters of at least part of the vehicle. The method includes de-biasing the physical data and applying a recursive statistical estimator, such as a Kalman filter, to the de-biased physical data and an output of the primary and secondary GNSS-receivers to determine a position and velocity of the vehicle.

Abstract: A flooring system for radiant heating includes a top floor portion and a subfloor portion. The top portion is releasably connectable to the subfloor portion in a vertical direction substantially perpendicular to a walking surface of the top portion. The top portion includes a bottom side and top channel portion downwardly depending from the bottom side. The subfloor portion includes a top side and a bottom channel portion extending upwardly from the top side. The top channel portion and the bottom channel portion bound a channel for receiving a heating conduit. The channel extends longitudinally relative to the top floor portion and the subfloor portion.

Abstract: A thermo-magnetic actuator includes operative components, preferably in a sealed container, from which a rotatable or translatable shaft extends. The shaft is driven by supplying electrical power to a heater in a closed chamber containing a working fluid that expands upon being heated. The expansion of the fluid drives a piston that, in turn, slides a rack coupled to the shaft. A ferromagnetic target is connected to the rack and attracted by a magnetic field produced by an electromagnet that receives electrical power from the same source as the heater. The attraction of the target causes an end of the target to latch magnetically and mechanically and to open an electrical switch, disconnecting current flow to the heater, without disturbing current flow to the electromagnet. The target is released and the rack and target return to their original positions upon termination of current flow to the electromagnet.

Abstract: Systems and methods for guiding a vehicle and vehicle sensor bias determination methods are disclosed. A method for guiding a vehicle includes a primary antenna of a primary survey-grade GNSS-receiver and a secondary antenna of a secondary GNSS-receiver mounted to the vehicle, which are at least temporarily receiving GNSS-signals of a global positioning system. A plurality of physical sensors mounted to the vehicle generate physical data indicative of respective measured physical parameters of at least part of the vehicle. The method includes de-biasing the physical data and applying a recursive statistical estimator, such as a Kalman filter, to the de-biased physical data and an output of the primary and secondary GNSS-receivers to determine a position and velocity of the vehicle.

Abstract: A wall covering system for radiant heating includes a first wall covering portion and a second wall covering portion. The first portion is releasably connectable to the second portion in a direction substantially perpendicular to an outer surface of the first portion. The first portion includes a bottom side and top channel portion downwardly depending from the bottom side. The second portion includes a top side and a bottom channel portion extending upwardly from the top side. The top channel portion and the bottom channel portion bound a channel for receiving a heating conduit. The channel extends longitudinally relative to the first portion and the second portion.

Abstract: A flooring system for radiant heating includes a top floor portion and a subfloor portion. The top portion is releasably connectable to the subfloor portion in a vertical direction substantially perpendicular to a walking surface of the top portion. The top portion includes a bottom side and top channel portion downwardly depending from the bottom side. The subfloor portion includes a top side and a bottom channel portion extending upwardly from the top side. The top channel portion and the bottom channel portion bound a channel for receiving a heating conduit. The channel extends longitudinally relative to the top floor portion and the subfloor portion.

Abstract: A multiple processor device stores a stream of data as a plurality of data segments, which includes multiplexed data fragments from at least one of a plurality of virtual channels. The data segments that comprise the stream of data correspond to the multiplexed data fragments from the virtual channels. The multiple processor device then decodes at least one data segment in accordance with one of a plurality of transmission protocols to produce a decoded data segment. The multiple processor device then stores the decoded data segment to align it in accordance with a data path segment size. The multiple processor device then interprets the stored decoded data segment with respect to a corresponding one of the plurality of virtual channels to determine a destination of the stored decoded data segment. The multiple processor device then stores the decoded data segment as part of reassembled data.

Abstract: A trailer lamp assembly has a moulded shell 9 closed by a red and amber lid 3, 4. A pair of raised wells 28 sit beneath the red and amber parts of the lid and each contains a multiple LED array 32 waterproofed by a pool of resin 36. A compartment 15 in the shell between the wells contains a downwardly directed further LED array 25. The incoming electric leads 42 pass through a plug of hardened resin 44 and enter a distributor box 38 likewise waterproofed by a pool of hardened resin 48.