Abstract: A drug delivery system for injecting a medicament is provided. The system includes a container configured to receive a medicament; a drive assembly which, upon actuation, is configured to expel the medicament from the container; a needle for injecting the medicament to a patient; a fluid path assembly comprising a tube in fluid communication with the container and the needle for conducting fluid from the container to the needle; and a tube crimping arrangement configured to engage the tube to block fluid flow through the tube. The drive assembly causes the tube crimping arrangement to engage the tube after a dose of the medicament has been delivered to the patient through the needle.

Abstract: The invention features the use of a defined microbial consortia for the replacement of a gut microbiome associated with disease. In particular, the invention provides for the treatment of hyperammonemia, Clostridium difficile colitis, hepatic encephalopathy associated with cirrhosis, and inflammatory bowel disease.

Abstract: A fabricated part for a high temperature operation including a non-metallic substrate formed of a polymer fabric of woven non-absorbent polymer filament. The substrate is heat-resistant and heat set at a temperature that is above a predetermined operating temperature of an operation of the fabricated part. The heat setting pre-shrinks/heat stabilizes the material, thereby reducing failure during use in high temperature and/or wet applications. The substrate is useful as an endless belt and other applications. The invention further includes an apparatus with a heating device configured to operate at the predetermined operating temperature, and the fabricated part within or extending through the heating device.

Abstract: A railway vehicle parking brake that can provide the appropriate tension to the braking system using a motor, a brake chain drum interconnected to the motor to take up or release a brake chain, a load arm deflects in response to tension in the brake chain, and a switch that is closed by the load arm when it deflects. A movable sheave interconnects the brake chain and the load arm and is positioned between the brake chain drum and a fixed sheave over which the brake chain is looped. A control method considers the position of the first switch to determine whether to the motor off when applying the brakes and the amount of current being drawn by the motor to determine whether to the motor off because of a system failure.

Abstract: A container having a flow end with an associated hole in a surface that matches a cutout in a cover that is inserted in the flow end. Rotation of the cover with the container aligns the hole with the cutout in the cover; to allow fluid flow when the system is placed downwards into a liquid body. When the liquid level in the container matches that in the liquid body, a base is inserted within a resting end of the container thereby restricting liquid flow in or out of the system. As the container is removed from the liquid, the cover at the flow end is twisted so that the hole in the container is covered thereby creating a closed system, blocking any fluid movement. The system is placed on the resting base and stored to compare at a later time with the Liquid Containment System.

Abstract: A dynamic belt-tensioning apparatus for a treadmill includes a base having a first end and a second end spaced from the first end. A foot-striking platform is movably supported by the base so as to allow vertical movement of the platform during operation of the treadmill. A drive belt has a fixed circumference and is positioned above a top portion of the platform. A drive roller is pivotally mounted adjacent to the first end of the base and engages the drive belt. A tensioning roller is pivotally mounted to the base and is capable of a range of movement to provide substantially constant tension to the drive belt in response vertical movement of the platform.

Abstract: A treadmill has a base with a vertically displaceable platform. A mechanism is provided that resists the downward movement of the platform in response to a load applied to the platform. The mechanism also rebounds the platform upwardly with a force applied to the platform in response to a decrease of a load on the platform. A support structure enables stable vertical positioning of the platform with respect to the base.

Abstract: A system and method for communicating data between a first software and a second software located on first and second devices, respectively, has a hardware driver and memory associated with each device. Each communication of data from the first software to the second software allocates memory to manage data to be communicated from the first software to the second software, provides memory allocation information to the hardware driver associated with the first software, and transmits the data from the first hardware driver to the second hardware driver for delivery to the second software via the memory associated with the second software.

Abstract: A Dedicated Embedded Microcomputer Analyzer Sanitizer mounts a USB memory device or other non-volatile memory device on a dedicated microcomputer under restricted file permissions, and features a network connection for connecting said dedicated microcomputer to a network. The Analyzer Sanitizer displays its IP address or hostname when connected to the network, and hosts a web interface accessible by entering the IP address or hostname into a web browser of any computer connected to said network, thereby isolating said computer from any malicious self-executing software on the non-volatile memory. The web interface includes selectable options for downloading, uploading, wiping, recovering or analyzing data content on the non-volatile memory.

Abstract: The invention features the use of a defined microbial consortia for the replacement of a gut microbiome associated with disease. In particular, the invention provides for the treatment of hyperammonemia, Clostridium difficile colitis, hepatic encephalopathy associated with cirrhosis, and inflammatory bowel disease.

Abstract: A drug delivery device includes a piston rod which extends along a longitudinal axis of the drug delivery device, wherein the piston rod is adapted to apply an axial load in the distal direction to a cartridge bung in order to dispense a medicament contained in the cartridge. In order to improve the convenience of the injection process and to mitigate the risk of underdosing due to a blocked needle a cartridge bung load indicator is provided, located at the distal end of the piston rod and adapted to abut against the cartridge bung, wherein the cartridge bung load indicator comprises an indicator element that audibly, tangibly and/or visually indicates a load state of the piston rod to the user.

Abstract: There is disclosed a cache memory controller for storing cache data within a cache, the cache data comprising an unsecured version data to corresponding secured first data.

Abstract: A locking mechanism for a brake cylinder that has a tube surrounding the hollow shaft of the brake cylinder with a first set of teeth formed along an outer surface thereof. A gate having a second set of teeth corresponding to the first set of teeth is moveable in between a first position, wherein the first and second set of teeth are engaged to prevent movement of the brake cylinder piston, and a second position where the first and second set of teeth are disengaged to allow movement of the brake cylinder piston. A spring biases the gate into the locked position and a supplemental piston responsive to a source of brake pipe pressure can move the gate into the unlocked position so that the main piston is free to move.

Abstract: Identifying the interactions of a selected cell across a hierarchical diagram of an integrated circuit and mapping the ways in which the cell can interact with other structures in the hierarchy reduces the computational load for design rule checking (DRC) and design rules for manufacturing (DRM). To this end, a cell and multiple instances of the cell are identified within hierarchical design levels of the chip. The interactions between the cell and other cells within the hierarchy are subtracted from the cell boundary, and the results of the subtracting are merged in the cell boundary. By subtracting the results of the merging, identical interactions are identified across the multiple instances of the cell. The results of the subtracting are used to generate a virtual hierarchical layer identical (VHLi) which aids in the simulation and verification of the chip.

Abstract: A mold prevention or mitigation solution includes one or more humidity monitors installed in an indoor environment and operable to monitor a current relative therein, an alarm server communicable with said one or more humidity monitors over a data network, and a network connection by which the alarm server is communicable with one or more meteorological server that provides current weather data. The alarm server receives a current relative humidity value from the one or more humidity monitors, automatically obtains a current outdoor temperature from the meteorological server(s), automatically adjusts a humidity alarm set point based on the current outdoor temperature, and automatically compares the set point against the current relative humidity value to trigger an alert in the event that said current relative humidity value exceeds the humidity alarm set point.

Abstract: A locking mechanism for a brake cylinder that has a tube surrounding the hollow shaft of the brake cylinder with a first set of teeth formed along an outer surface thereof. A gate having a second set of teeth corresponding to the first set of teeth is moveable in between a first position, wherein the first and second set of teeth are engaged to prevent movement of the brake cylinder piston, and a second position where the first and second set of teeth are disengaged to allow movement of the brake cylinder piston. A spring biases the gate into the locked position and a supplemental piston responsive to a source of brake pipe pressure can move the gate into the unlocked position so that the main piston is free to move.

Abstract: Semiconductor designs are large and complex, typically consisting of numerous circuits called cells. To handle complexity, hierarchical structures are imposed on the semiconductor design to help accomplish analysis, simulation, verification, and so on. The hierarchical structures define architecture, behavior, function, structure, etc. of the semiconductor design. Virtual cells are constructed to compress cell geometries and ease the various design tasks. A cell and multiple instances of the cell are identified within the semiconductor design and the virtual hierarchical levels describing the design. Virtual hierarchical layer (VHL) data based on the cell is loaded. A virtual cell model representative of the cell is obtained. Interactions between cell data and VHL data are determined, and relevant portions of shapes are selected. Data within the virtual cell model is reduced based on the determined interactions.

Abstract: A virtual hierarchical layer (VHL) is constructed for a semiconductor design in order to reduce the computational requirement of design rules checking (DRC) and design rules for manufacture (DRM) procedures. In order to form the VHL, a negative plane is created. A cell and multiple instances of the cell are then identified in the semiconductor design and polygons which overlap the cell and its instances are determined. The polygons are pushed into the negative plane to create holes in the plane. Shapes overlapping other instances of the cell which fall onto holes in the solid virtual cell plane are ignored. The resulting holed solid virtual cell plane can then be inverted to create a VHL to be used for design simulation and verification.

Abstract: A flexible composite conveyor belt, such as for use as a belt wrapper in overlying combination with a metal belt in cooking or heating operations. The belt includes a protrusion attached to a flexible substrate. The protrusion includes an engagement surface adapted to secure the protrusion to a portion of the underlying metal belt to drive the belt at a same speed as the conveyor belt. Protrusions on opposing ends of the belt negate the need for conventional lacing in securing the ends of the belt together.

Abstract: A microcomputer-based controller has control outputs operably connected to a hydronic boiler of a building, a network connection for receiving weather forecast information from a meteorological server, and an input operably connected to an outside temperature transducer. The controller is configured to an appropriate set-point temperature for the boiler based on both the current outside temperature and a forecasted outdoor temperature from the meteorological server. Remote zone temperature sensors report zone temperatures to the controller, based on which further adjustment of the set point temperature are made if a notable number of zones all have temperatures notably shifted in a same direction from a normally expected zone temperature. The zone temperature sensors and controller are connected as nodes in a mesh network.